제주물을 이용한 기능성 및 혼합음료의 개발방향 설정에 관한 연구

고성보(Ko, Seong-Bo),현창석(Hyun, Chang-Seok),강경원(Kang, Kyung-Won) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.5

세계적으로 건강기능식품의 주변 환경은 매우 빠르게 변하고 있다. 2012년 세계기능성 음료시장은 269억달 러 규모, 아태지역 시장은 136억달러 규모가 될 것으로 전망하고 있다. 국내 먹는 샘물 시장은 2008년 4,400억원 규 모를 형성하고 있고, 제주삼다수의 매출액은 891억원이다. 그러나 “제주삼다수”라는 브랜드는 한계성을 지니고 있다. 이에 대한 방안으로 제주물의 품질 우수성을 알리는 포괄적인 광고가 필요하며, 제주 물을 이용한 기능성 음료 및 혼 합음료 개발의 성공 가능성을 높이기 위해서 제주워터(Jeju Water)라는 글로벌 통합브랜드 개발이 필요하다. 기능성 및 혼합음료 제품개발시 제주지역의 농산물의 기능성을 적극 활용해 물산업과 제주의 1차산업을 연계해 농산물의 과 잉생산 처리와 고부가가치화를 촉진시킬 필요가 있다. The environment of the health food in the world has been changed very rapidly. The world market volume of functional drinks in 2012 will be estimated at $ 26.9 billion, and Asia-Pacific market is expected to be $ 13.6 billion. The domestic market volume of bottled water in 2008 was 440 billion won, and "Jeju Samdasu" sales was 89.1 billion won. But the brand of "Jeju Samdasu" has the limits. As a solution, the comprehensive advertising of the excellence quality of Jeju water is required. To increase the likelihood of success in development of functional and mixed drinks by the water is necessary to develop a global integrated brand. In developing the functional and mixed drinks by the water, we apply the functionality of the Jeju agricultural products actively, and connect Jeju Water industry with Jeju agricultural industry, which promote the overproduction control and the high value- added agricultural products.

Simone Weil의 不幸의 意識에 관한 考察 : 工場生活의 經驗을 中心으로

高元禧 제주대학교 1977 논문집 Vol.9 No.1

Il ne suffit pas a` Simone Weil de donner des conseils et d’e´laborer une doctrine sociale; elle veut partager le malheur d’une classe opprime´e. Consciente de l’importance du travial manuel, elle de´cide d’en faire l’expe´rience. Simone Weil a de´nonce´ dans le travail mort un mode d’activite´ essentiellement inhumain et me^me anti-humain. Dans le travail mort, l’homme n’est plus un e^tre pensant, mais un objet comme ceux qu’il est condamne´ a `produire. Et il produit uniquement pour ne pas mourir do faim; il n’est Pas question pour lui de participer consciemment a` l’effort immense de production auquel collaborent en face tous les travailleurs de toutes les spe´cialistes. Le travailleur mort est coupe´ de son ouvrage, coupe´ de ses compagnons et de leur ouvrage, coupe´ de l’humanite´, de lui-m^eme et de l’univers; il est donc coupe´ de la vie et du vrai bonbeur. Et derrie`re lui, c’est toute la masse des hommes qui est coupe´e d’elle-me^me, du monde re´el et des fins re´elles. Au travail mort, qui laisse l’ouvrier ignorant de son ro^le propre dans l’ensemble de la production, Simone Weil envisage de substituer co qu’elle appelle le travaille conscient. Sa manie`re de vivre, son tempe´rament supra-intellectuel, sa gaucherie sur le plan manuel, autant d’e´le´ments qui aggravent pour Simone Weil la durete´ de la vie ouvrie´re. Nous no voulons pas nier le caracte´re inhumain du travail en usine, mais il nous faut remarquer qu’il est conside´rablement majore´ pour Simone Weil. Ses jugements subirent aussi le centre-coup de son inadaptation personnelle. Simone Weil n’ignorait point le malheur, elle en e´tait obse´de´e, mais ce contact avec la masse anonyme lui donne un sens aigu de la souffrance. Pour elle, aussi, c’e´tait l’amour des malheureux qui dominait. Cette compassion des malheureux est un des traits essentiels do sa vie profonde. Cependant, Simone Weil e´tait loin de se sentir satisfaite; a`qui aime vraiment, la compassion est un tourment. En 1934 elle de´cida de prendre, dans toute sa durete´, la condition ouvrie`re. Elle y connut la faim, la fatigue, les rebuffades, l’oppression du travail a` la chai^ne, l’a´ngoisse du cho^mage. Pour elle, co n’e´tait pas une expe´rience, mais une incarnation re´elle et totale, Son journal d’usine est un te´moignage poignant. L’e´preuve surpassa ses forces: son a^me fut comme e´crase´e par cette conscience du malheur; elle en restera marque´e toute sa vie. Bien entendu, il est aise´ de trouver chez Simone Weil des constantes, nous dirions des constantes essentielles dans le sens de la charite´ et du sacrifice, dans l’ordre surtout d’une direction d’existence voue´e l’Absolu. La frame est identique, seul ledessin change, mais le dessin pout masquer la frame. Ce qui forme l’essence de la vie de Simone Weil, c’est son amour de la ve´rite´.

과도 절삭에서의 절삭 공정 시뮬레이션

고정훈,조동우,윤원수,김주한 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

In most of the existing mechanistic models, the cutting process simulation is often restricted to a single path machining operation under a fixed cutting condition. Complex cutting processes such as die or mold manufacturing, however, are performed under two- or three-dimensional multiple tool paths. Since the tool paths in CNC machining are composed of line and arc segments, transient cuts are frequently occured due to the multiple paths. Even in steady cuts, the width of cut is varied with each segment. In this regard, this paper deals with the development of process simulation system for transient cuts, where continuously changing cutting configuration is computed, and then the cutting forces are predicted.

朱震亨의 中風論에 관한 考察

고경덕,이동원,정승현,신길조,이원철 동국대학교 한의학연구소 1997 東國韓醫學硏究所論文集 Vol.6 No.1

朱震亨은 金元四大家중 가장 후대의 인물로서 朱子學의 철학적 배경에 근거하여 劉河間, 張子和, 李??의 장점을 흡수하여 醫論을 펼쳤으므로, 金元四大家의 中風 內因論을 인식하는데 있어 그 의미가 크다. 朱震亨 中風論의 특징은 그가 거처한 純域的 特性에 근거하여 肥瘦人과 半身不遂의 左右에 따라 각각 治法을 달리하였으나, 中風 病因病理를 濕痰生熱로 보고 內因의 주요소로 痰을 중시하여 中風入方藥物은 治痰한다는 원칙에 기준하여 藥物을 사용하였다. 이러한 독특한 中風論은 후대 中風 內因論의 발전에 지대한 영향을 주었으므로, 이에 관한 연구는 中風 內因論 측면에서 韓醫學發展에 寄與할 것으로 恩慮된다. We inquired into the origins, pathologies, theraphies and prescriptions of Jungpung(中風) especially on the ground of Keokchiyeron(格致餘論)ㆍDangeosimbub(丹溪心法) written by JuJinHyoung(朱震亨) as modical blocks, from this study we could get that conclusions. 1. According to special feature of the theroies of JuJinHyoung's(朱震亨) Jungpung(中風) he thought pathologies of Jungpung(中風) as 「sub seong dam dam seong yeol yeol seong puns 濕疾痰痰生熱 熱生_風」through studying stress on regional characteristics and thought much of dam(疲) as one of major elements of internal causes. 2. He suggested chi-dam(治痰) in the first place in the treatment of Jungpung(中風) and emphasises the treatment using Succus Pyllostachyos(竹瀝), waterly extracted Rhizoma Zingiberis(鐘汁) in that they had the virtues of sodam-ganghwa(消痰降火), geo-gyeongrak(開經絡), haeng-heolgi(行血氣). 3. He treated differently whether a man in fat and thin, and have right or left hemiplegia, but he prescribed herb-medications on the principle that medications should have the virtues of chi-dam(治痰).

觀光客 動機에 關한 理論的 考察 : 動機理解와 方法論을 中心으로

高元圭 진주여자전문대학 1989 論文集 Vol.11 No.-

"Why do people travel?", This question is difficult to answer because the deeper psychological reasons. The answer pose a number of difficulties steming from two sources:Fist, individual and their cultural conditioning. Second. The possibility that "what the traveler says are 'his motivation for travelling may only be reflection of deeper needs, needs which he himself does not understand nor wish to articullate." The first point is largely definitional, and the second is epistemological and methodological. In many respects, this thesis has raises more questions than it has proposed solutions. But, having surveyed a number of view points in the study of tourist motivation, definition has not been supplied. That would be too ambition a project. Instead a description of tourist motivation has been offered, together with its possible advantages and methodological ramification. The elements of the discription, it is maintained, constitute the broad lines wherein the possibility of pluralist acceptance resides.

방선균 분리주가 생산하는 Phospholipase C 저해물질인 MT2617-2B의 분리 및 특성

고학룡,이현선,오원근,안순철,김보연,강대욱,민태익,안종석 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1

방선균 분리주 MT2617-2의 배양액으로 부터 phospholipase C (PLC) 저해물질인 MT2617-2B를 n-butanol 추출 및 column chromatography 법을 이용하여 분리하였다. MT2617-2B는 IR ^13C- 및 ^1H-NMR 그리고 ESI-MS에 의한 구조분석 결과, 한 개의 hemiketal ring, polyhydroxyl 및polymethyl groups으로 구성되었으며 side chain으로 한 개씩의 malonate 및 guanidine group을 가지는 분자량 1057의 macrolide 화합물이었다. 따라서, MT2617-2B를 기존의 macrolide 항생제인 copiamycin 및 niphithricin A로 동정하였다. 한편, MT2617-2B는 methanol 용액에서 실온에서 방치하였을 때 도일한 분자량을 가진 두 개의 이성질체를 생성하였다. PLC γ1과 -β1에 대해 각각 25 및 50㎍/㎖의 IC_50 값을 가지며, Staphylococcus aureus 와 Candida albicans에 대해서는 항균활성을 나타내지만 Escherichia coli에는 나타내지 않았다. A phospholipase C (PLC) inhibitor (MT2617-2B) was isolated from the culture broth of actionmycetes isolate MT2617-2 by the extraction with n-butanol and column chromatographic techniques. The molecular weight of the inhibitor was 1057, by the spectroscopic analyses of IR ^13C- and ^1H-NMR and ESI-MS. The chemical structure of MT2617-2B was found to be a macrolide compound consisted of a hemiketal ring, polyhydroxyl and polymethyl groups, which had a malonate and guanidine group as its side chain. MT2617-2B produced its two isomers having the same molecular weight by standing in methanol solution at room temperature. Therefore, MT2617-2B was identified as copiamycin and niphithricin A, macrolide antibiotics. The values of IC_50 against PLC γ1 and PLC-β1 were 25 and 50㎍/㎖, respectively. MT2617-2B had antimicrobial activities against Staphylococcus aureus and Candida albicans, but not against Escherichia coli.

뼈흡수유도호르몬이 ROS17/2.8세포로부터 Nitric Oxide 형성에 미치는 영향

고선일,김민성,한원정,김세원,김정근 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.3

Purpose : We performed the present study to investigate whether osteotropic hormomes play roles on the nitric oxide (NO) production in culture of ROS17/2.8 osteoblastic cells. Materials and Methods : The osteoblastic cell line ROS17/2.8 cells were cultured in F12 medium supplemented with 5% fetal bovine serum (FBS) at 37?C in a humidified atmosphere of 5% CO₂ in air. ROS17/2.8 cells were plated in 96-well plates at a density of 2-3×10³ cells/well and grown to confluence. Then the cells were pretreated with osteotropic hormones (parathyroid hormone (PTH) 20-500 ng/mL, 1,25 dihydroxycholecalciferol (1,25[OH]₂D₃) 1-100 nM; prostaglandin E₂ (PGE₂) 20-500 ng/mL) in the medium supplemented with 0.4% FBS for 72 hours and the cells were treated with cytokines (TNFα and IFNγ) in phenol red-free F12 medium for an additional 48 hours. NO synthesis was assessed by measuring the nitrite anion concentration, the reaction product of NO, in the cell culture medium using Griess reagent. Results : PTH and 1, 25[OH]₂D₃ pretreatment induced a significant increase in NO production in the presence of TNFα and IFNγ. PGE₂ slightly induced NO production compared to the control group. But, PGE2 pretreatment did not affect in NO production in the presence of TNFα and IFNγ. Conclusions : These results suggest that the actions of osteotropic hormones in bone metabolism may be partiallymediated by NO in the presence of cytokines.

混合 Starter Culture를 利用한 醱酵 Sausage 製造에 관한 硏究 : 分離菌株의 生育特性 및 培養條件 Growth Characteristics and Culture Conditions of Isolated Strains

고명수,윤원호 건국대학교 1989 論文集 Vol.29 No.2

Micrococcus varians, Staphylococcus carnosus, Lactobacillus plantarum and Pediococcus acidilactici were isolated from mixed smarter cultures for the fermented meat products, and then their growth characteristics and cultural conditions were investigated. The optimum temperature and pH for the growth of all the isolated strains were around 30∼ 35℃ and pH 6.0∼ 7.0, respectively, except optimum temperature (40℃) of Pediococcus acidilactici All the isolated strains were grown on the NaCl concentration of 8.0%, particularly Staphylococcus carnosus was grown on the NaCl concentration of 14.5%. Micrococcus varians and Staphylococcus carnosus grew with glucose under anaerobic condition and showed positive reaction to catalase production and nitrate reduction. Lactobacillus plantarum and Pediococcus acidilactici showed homo fermentative type which was not produced CO2 with glucose, and showed positive reaction to acetoin production, All the isolated strains produced acid with fructose, glucose and mannose. On the other hand, there was no strain that produced acid with inositol and inulin.

Simone Weil의 종교관에 대한 고찰(I)

고원희 濟州大學 敎養學部 1975 論文集 Vol.4 No.-

Certains ont pens? et e'crit que le christianisme de Simone Weil e'tait, ou tendait a' e'tre, une abstraction philosophique de type platonicien, et que son Christ ressemblait aux id?es de Platon. Je le sais qu'elle a souvent une manie're a' elle de parler du Christet surtout de Dieu, qui fait penser a' un e'tre plut?t impersonnel; I'Absolu, dont elle est dans le monde un des meilleurs t?moins, mais qu'elle exprime Souvent avec maladresse, avec des informations parfois erron?es ou h?tives, dans une forme empreinte d'esprit math?matique et de spinozisme, est celui de la foi catholique. Par la compassion aux malheureux, Simone Weil, quelques dix ans plus tard, devait faire la decouverte de Dieu et de son Christ. L'amour de l'homme et le besoin de partager r?ellement la peine du plus malheureux ?tait l'un des traits marquants de son ?tre spirituel. La m?me attraction et le m?me vertige de l'Absolu se retrouvent dans l'attitude de Simone Weil ? l'?gard de l'?glise catholique.

알베르 까뮈와 시몬 베이유와의 比較硏究

高元禧 제주대학 1978 논문집 Vol.10 No.1

Camus a souvent évoqué l'auteur de l'ateur de l'Enracinement. Il ne la découvrit pourtant qu'au lendemain de la Libération de la Libération. Il eut alors la charge d'éditer, non sans difficultés ㅣ'essentiel de son oeuvre. Il appréciait son indépendance d'éditer, non sans difficultés l'essentiel de son oeuvre. Il appréciait son indépendance d'esprit l'esprit l'intransigeance qui la poussait à l'engagement total. La sympathie qu'il portait à Simone Weil et à son oeuvre a sans doute contribué à rapprocher Camus des milieux syndicalistes revolutionnaires oú elle avait longtemps évolué et où il retrouvait la même flmme intransigeante. On trouvera ici la présentation de l'Enracinement écrite par Camus pour le Bulletin de la N. R. F. (juin 1949 ) et un texte plus long, retrouvé en manuscrit; il s'agit là, semble-t-il, d'un projet de préface qu'il renonça à rédiger définitivenment, à la suite de devergences avec certains porches de Simone Weil. Voici ce que Camus dit: Simone Weil n'était prévenue contre rien sinon contre la cruauté ou la bassesse, ce qui revient au même. Elle n'a jamais rien méprisé sinon le mépris lui-même et, à la lire, on se dit que la seule chose dont fût incapabel sa surprenante intelligence était la frivolité. On lui demande en 1940 un rapport sur la situation morale de la France et elle écrit le livre publié aujourd'hui sous le titre l'Enracinement, véritable traité sur la civilisation. Tel set le personnage qui allait toujours, et comme naturellement, à l'ssentiel. L'Enracinement contient piusieurs des clés qui permettent de comprendre Simone Weil. Mais ce livre, un des plus importants, à mon sens, qui aient paru depuis la guerre, jette aussi une lumière puissante sur l'abandon où se débat l'Europe. Et il fallait peut-être la défaite, l'hébétude qui l'a suivi et la méditation taciturne que tout un peuple a poursuice dans les annéesobscures pour que des idées 면냐 inopportunes, des jugements qui renversent tant d'idées reçues, qui ignorent tant de préjugés, puissent trouver enfin chez onus leur exact retentissement. A. Camus a écrit qu'il me paralt impossible d'imaginer pour l'Europe une renaissance qui ne tienne pas compte des exigences que Simone Weil a définies. Simone Weil examine les rapports entre l'indivi여 et la collectivité. Elle montre les failles du monde moderne, la décomposition de la société contemporaine et esquisse les conditions d'une intégration harmonieuse de l'homme-et avant tout de l'ouvrière-dans un ensemble équilibré.