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      • Network Security in Embedded System Using TLS

        Vivek Negi,Himanshu Verma,Ipsita Singh,Aditya Vikram,Kanika Malik,Archana Singh,Gaurav Verma 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.2

        Security in terms of Networks have turn out to be more significant to Organizations, Military and personal computer user’s. Since various kinds of threats are for data from sending it from sender side over internet till it reaches to receiver. Here we will focus on SSL it is a technique used to give client and server authentication, data confidentiality and data integrity. It transform our data into unintelligible form, data which we will be sending can be text or no text form, by encrypting our data we can save it from attacks like eavesdropping, in which interception of communication by unauthorized person, he can either listen or can add malicious information in our data which can lead to catastrophic results. This technique of secure data transmission is very useful in securing the integrity of data sent by the Unmanned Aerial Vehicles in military application to commercially used Electricity meter. Since the above mentioned devices uses microcontroller to send data through internet hence this data is always going to be susceptible to above mentioned threats so it is important to ensure that it doesn’t fall in wrong hands, our objective is that our microcontroller sends the data to remote location has authenticity, confidentiality and integrity. First we will send some meaningful text already stored in controller of STM3240G Eval-board then that data will be sent to server. These encrypted packets will be sending to remote server through Ethernet. At the receiver end this data will be received and decrypted to get the original captured data.

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        Leptin DNA Methylation and Its Association with Metabolic Risk Factors in a Northwest Indian Obese Population

        Sadashiv,Anupama Modi,Manoj Khokhar,Praveen Sharma,Rajnish Joshi,Sudhanshu Shekhar Mishra,Rajay N Bharshankar,Sunita Tiwari,Pankaj Kumar Singh,Vivek Vidyadhar Bhosale,Mahendra Pal Singh Negi 대한비만학회 2021 The Korean journal of obesity Vol.30 No.3

        Background: It is well established that obesity is a major health risk in diabetes and associated diseases. Epigenetic changes, specially DNA methylation, play an important role in regulation of adipokines. The objective of the present study was to evaluate the DNA methylation status at the promoter region of the leptin gene in obese individuals and its association with metabolic risk factors. Methods: The study included obese (n=100) and non-obese (n=75) individuals aged 25–45 years, and measured their physical, biochemical parameters (glucose, insulin, and lipid profiles) and leptin, DNA methyltransferase 1 (DNMT1), and DNA methyltransferase 3 beta (DNMT3b) mRNA expressions with real-time reverse transcription-polymerase chain reaction (qRT-PCR). DNA methylation of the leptin gene at the promoter region was analyzed by methyl-specific qPCR . Results: The study found that the DNA methylation level at the promoter area of the leptin gene was negatively associated with weight in obese subjects. Furthermore, study findings showed that the DNA methylation level was negatively associated with fasting insulin, glucose, homeostatic model assessment for insulin resistance, and total cholesterol. There was also a higher expression of DNMT1 and DNMT-3b in obese subjects as compared with non-obese subjects. Conclusion: The leptin epigenetic profile may be associated with obesity and its associated metabolic risk factors.

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