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      • KCI등재

        The branching patterns and termination points of the facial artery: a cadaveric anatomical study

        Vu Hoang Nguyen,Lin Cheng-Kuan,Tuan Anh Nguyen,Trang Huu Ngoc Thao Cai 대한두개안면성형외과학회 2024 Archives of Craniofacial Surgery Vol.25 No.2

        Background: The facial artery is an important blood vessel responsible for supplying the anterior face. Understanding the branching patterns of the facial artery plays a crucial role in various medical specialties such as plastic surgery, dermatology, and oncology. This knowledge contributes to improving the success rate of facial reconstruction and aesthetic procedures. However, debate continues regarding the classification of facial artery branching patterns in the existing literature. Methods: We conducted a comprehensive anatomical study, in which we dissected 102 facial arteries from 52 embalmed and formaldehyde-fixed Vietnamese cadavers at the Anatomy Department, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. Results: Our investigation revealed eight distinct termination points and identified 35 combinations of branching patterns, including seven arterial branching patterns. These termination points included the inferior labial artery, superior labial artery, inferior alar artery, lateral nasal artery, angular artery typical, angular artery running along the lower border of the orbicularis oculi muscle, forehead branch, duplex, and short course (hypoplastic). Notably, the branching patterns of the facial artery displayed marked asymmetry between the left and right sides within the same cadaver. Conclusion: The considerable variation observed in the branching pattern and termination points of the facial artery makes it challenging to establish a definitive classification system for this vessel. Therefore, it is imperative to develop an anatomical map summarizing the major measurements and geometric features of the facial artery. Surgeons and medical professionals involved in facial surgery and procedures must consider the detailed anatomy and relative positioning of the facial artery to minimize the risk of unexpected complications.

      • KCI등재

        High-Frequency Interdigitated Array Electrode-Based Capacitive Biosensor for Protein Detection

        Tuan Vu Quoc,Viet Nguyen Ngoc,Tung Thanh Bui,Chun-Ping Jen,Trinh Chu Duc 한국바이오칩학회 2019 BioChip Journal Vol.13 No.4

        This paper reports a study on developing of a protein detection biochip based on interdigitated array electrodes (IDAEs) capacitive immunosensor. The protein after being preconcentrated in a detection region will be selectively captured and detected by the capacitive immunosensor. Using electrical impedance spectroscopy operated at high-frequency in the range of 100 kHz–1 MHz, the capacitance of the gold electrode is determined and the antibody surface modification steps can be also monitored. The experiment results show the capacitance changes in accordance with the adding biochemical layer on gold electrodes for each step of the antibody surface modification. In particular, the total impedance operated at 1 MHz frequency has been seen to change from 2.1 kΩ of bare chip (before antibody surface modification) to 8 kΩ after antibody surface modification process while the serial capacitance is recorded to reduce steadily from 450 pF to 55 pF. Also, the efficiency of protein chip was investigated by implementing the measurement of 10 µM BSA with and without preconcentration process. The measurement results have shown the sensitivity increasing significantly after the protein is preconcentrated in this chip. The results demonstrate high efficiency of protein detection can be achieved by operating high frequency capacitive measurement on IDAEs capacitive immunosensor.

      • KCI등재

        Effectiveness Analysis of Spin Motion in Reducing Dispersion of Sounding Rocket Flight due to Thrust Misalignment

        Vu Dan Thanh Le,Anh Tuan Nguyen,Lac Hong Nguyen,Ngoc Thanh Dang,Ngoc Doan Tran,한재흥 한국항공우주학회 2021 International Journal of Aeronautical and Space Sc Vol.22 No.5

        This paper explores the effectiveness of spin motion in mitigating the flight dispersion of a two-stage solid-propellant rocket model due to thrust misalignment. The aerodynamic coefficients of the rocket model are obtained by the use of a panel method and semi-empirical equations. A simulation program is developed to solve the equations of motion while considering the variations of the inertial parameters. Monte Carlo simulation techniques are applied to provide statistical data that are used to analyze the relationship between the spin motion and flight dispersion. The spin motion is generated by canting the fins to generate the axial aerodynamic moment. The results show that thrust misalignment at the first stage of the rocket has a great impact on the dispersion of rocket flight. By canting the first-stage fins at a relatively large angle to create the spin motion right after launch, the dispersion area of the payload-release location can be minimized considerably. However, thrust misalignment as well as the fin cant angle at the second stage appear to have insignificant effects on the rocket flight trajectory. On the other hand, canting the fins of the second stage at a large angle may lead to an increase in the spin rate, which may be harmful to the rocket operation. The paper also shows the variation of the dispersion characteristics of rocket flight when the fin size is modified.

      • KCI등재

        Improvement of Tomato Seedling Quality under Low Temperature by Application of Silicate Fertilizer

        Ngoc-Thang Vu(넉탕부),Anh-Tuan Tran(안추안트란),Thi-Tuyet-Cham Le(띠투엣참리),Jong-Kuk Na(라종국),Si-Hong Kim(김시홍),Jong-Man Park(박종만),Dong-Cheol Jang(장동철),Il-Seop Kim(김일섭) (사)한국생물환경조절학회 2017 시설원예‧식물공장 Vol.26 No.3

        규산 시비가 토마토 플러그 묘소질에 미치는 영향과 묘의 저온저장시 규산의 저온장해 경감효과를 검토하였다. ‘Rapito’품종을 공시하여 30일간 32구 규격의 플러그 트레이에서 육묘한 뒤, 여섯 개의 규산 처리농도구 (8, 16, 32, 64, 128 및 256mM)를 설계하여 20일 동안 주 2회 관주 처리한 뒤, 묘소질을 대조구와 비교하였다. 처리 농도는 16mM과 32mM 처리가 초장, 엽면적, 생체중, T/R율 및 근권부 발육 등 대부분의 생육지표에서 타 처리구에 비해 양호했으며, 특히 16mM의 농도에서 가장 좋은 묘소질을 보였으나, 64mM 이상의 고농도에서는 대조구에 비해 전반적으로 생육이 억제되는 경향을 보였다. 토마토 묘의 생리적 반응에서 엽온에서는 처리구별 차이가 나타나지 않았으나, 증산율은 32mM이상의 농도 처리구에서 기공확산 저항이 증가하면서 증산율이 감소되는 경향을 보였다. 또한, 처리 횟수에 따른 효과를 검토하기 위해 16mM농도의 규산을 20일 동안 6, 10, 20회 관주처리 한 결과, 대부분의 생육지표에서 처리 횟수간에는 큰 차이가 없었으나, 무처리구에 비해 묘소질이 향상되었으며, 특히 뿌리표면적, 근장, root tip수등 근권부의 생육이 현저히 증가하였다. 아울러 규산처리가 저온저장시 토마토 묘의 저온장해를 감소시키는 효과가 있음을 확인하였다. The object of this study was to improve tomato seedling quality in low temperature(below 7, 10℃ during night time or daily mean air temperature was 18℃) by application of silicate fertilizer. Six different silicate fertilizer concentrations (8, 16, 32, 64, 128, and 256mM) or water as the control were applied to tomato seedlings twice a week for 20 days. Positive effects were observed in the growth parameters of the seedlings treated with 16 and 32mM silicate fertilizer; the most effective concentration of silicate at which seedlings showed the best performance was 16mM. However, a high concentration of silicate (256mM) caused negative effects on the growth. The transpiration rate decreased alongside with the increase of silicate concentration up to 32mM, possibly due to the increased stomatal diffusive resistance. Silicate stimulated the growth and development of tomato seedlings, resulting in increased growth parameters and root morphology. However, no significant differences were observed among treatment numbers of soil-drenching wuth the silicate (6, 10, or 20 times with 16mM) for 20 days, suggesting that silicate treatment with 6 times may be sufficient to induce the silicate effects. The application of 16mM of silicate fertilizer reduced relative ion leakage and chilling injury during low temperature storage. In addition, the seedlings treated with silicate fertilizer recovered faster than those without silicate treatment after low temperature storage.

      • KCI등재SCOPUS

        Facial artery: anatomical variations in the perioral region in cadavers

        Vu Hoang Nguyen,Lin Cheng-Kuan,Tuan Anh Nguyen,Trang Huu Ngoc Thao Cai Korean Cleft Palate-Craniofacial Association 2023 Archives of Craniofacial Surgery Vol.24 No.6

        Background: In recent years, there has been an increase in reports of perioral vascular complications resulting from filler injections, such as necrosis of the lip or alar rim, occlusion, and in severe cases, blindness. Conversely, the use of perioral arterial flaps is becoming more prevalent in the treatment of cleft lips, cancer, and trauma. A thorough understanding of perioral arteries is essential to minimize complications and maximize the success of these flaps. However, the course of the facial artery (FA) in the perioral region remains incompletely understood. The aim of this study was to describe the variations of the FA in the perioral region. Methods: We dissected 52 embalmed and formaldehyde-fixed Vietnamese cadavers. We then studied the size and distribution of perioral arteries in 102 specimens. Results: The superior labial artery (SLA) was the most common branch, occurring in 87.25% of cadavers, followed by the inferior labial artery (ILA) at 78.43%. The SLA primarily originated above the mouth corner (cheilion), accounting for 91.01% of cases, and predominantly exhibited a tortuous course within the submucosa (78.65%). The ILA's branching pattern varied, but it was primarily located below the cheilion (91.25%). The ILA also followed a twisted path, generally within the submucosa. The ILA exhibited two patterns: the typical pattern, distributed at the vermilion border of the lower lip (8.82%), and the horizontal labiomental artery pattern, which ran horizontally in the middle of the lower lip area (69.61%). At their origin, the SLA and ILA had average external diameters of 1.29 mm and 1.28 mm, respectively. Conclusion: Numerous anatomical variations in the FA in the perioral region were found. A detailed anatomic description, suggested landmarks, and angiography before the procedure will be useful to help doctors avoid complications.

      • KCI등재

        Phytochemical and pharmacological properties of Myristica fragrans Houtt.: an updated review

        HAMANH TUAN,Ngoc Khanh Vu,Thu Huong Tran,Jeong Ah Kim,Mi Hee Woo,Byung Sun Min 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.11

        Myristica fragrans Houtt. (Myristicaceae), anaromatic evergreen tree, is well known as a commercialsource of mace (aril) and nutmeg (seed), which have longbeen widely used as spices in the culinary field. In addition,various parts of M. fragrans have been used in folk medicinefor treating several diseases. Since its extensive uses inthe culinary sector and folk medicine, M. fragrans has longattracted a great deal of attention from pharmacologists andchemists. Numerous studies have indicated that M. fragranscontains diverse phytochemicals such as lignans, neolignans,diphenylalkanes, phenylpropanoids, and terpenoids, whichexhibit many of pharmacological activities. Among them,macelignan (1), meso-dihydroguaiaretic acid (2), myristicin(111), and malabaricone C (Mal C, 104) are the most activecompounds. The aim of this review is to comprehensivelysummarize the phytochemical and pharmacological propertiesof M. fragrans that have reported to date.

      • KCI등재

        Evaluating Load-Carrying Capacity of Short Composite Beam Using Strain-Hardening HPFRC

        Duy-Liem Nguyen,Vu-Tu Tran,Ngoc-Thanh Tran,Tri-Thuong Ngo,Manh-Tuan Nguyen 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.4

        The main goal of this study was to develop the short composite beams using strain-hardening fiber-reinforced concrete (S_HPFRC) and conventional concrete (CC) together. Firstly, the sensitivity of the hybrid fiber system to the enhancement of mechanical properties of plain high performance concrete (P_mortar) was experimentally studied. The ranking of the mechanical properties in terms of sensitive coefficient was observed as follows: direct tensile > splitting tensile > compressive. Next, the responses of short composite beams with various thicknesses of S_HPFRC were investigated under a three-point bending test (3PBT). Six beams with no reinforcement (type A) and six beams with reinforcement were tested (type B) with their identical dimensions of 150 × 150 × 300 mm (depth × width × span length). The compressive strength of S_HPFRC and CC were about 80.65 MPa and 21.12 MPa, respectively. Most of the composite beams were observed to fail in shear mode. And, there was a favorable effect on enhancing the load-carrying capacity of a beam as S_HPFRC was placed at a critical tensile zone. Finally, based on the test data, the analytical equations were proposed for the purpose of predicting shear resistance of the S_HPFRC - CC beam.

      • Tobacco Control Policies in Vietnam: Review on MPOWER Implementation Progress and Challenges

        Hoang, Van Minh,Tran, Thu Ngan,Vu, Quynh Mai,Nguyen, Thi Tuyet My,Le, Hong Chung,Vu, Duy Kien,Tran, Tuan Anh,Nguyen, Bao Ngoc,Vu, Van Giap,Nguyen, Manh Cuong,Pham, Duc Manh,Kim, Bao Giang Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1

        In Vietnam, the WHO Framework Convention on Tobacco Control (WHO FCTC) took effect in March 2005 while MPOWER has been implemented since 2008. This paper describes the progress and challenges of implementation of the MPOWER package in Vietnam. We can report that, in term of monitoring, Vietnam is very active in the Global Tobacco Surveillance System, completing two rounds of the Global Adult Tobacco Survey (GATS) and three rounds of the Global Youth Tobacco Survey (GYTS). To protect people from tobacco smoke, Vietnam has issued and enforced a law requiring comprehensive smoking bans at workplaces and public places since 2013. Tobacco advertising and promotion are also prohibited with the exception of points of sale displays of tobacco products. Violations come in the form of promotion girls, corporate social responsibility activities from tobacco manufacturers and packages displayed by retail vendors. Vietnam is one of the 77 countries that require pictorial health warnings to be printed on cigarette packages to warn about the danger of tobacco and the warnings have been implemented effectively. Cigarette tax is 70% of factory price which is equal to less than 45% of retail price and much lower than the recommendation of WHO. However, Vietnam is one of the very few countries that require manufacturers and importers to make "compulsory contributions" at 1-2% of the factory price of cigarettes sold in Vietnam for the establishment of a Tobacco Control Fund (TCF). The TCF is being operated well. In 2015, 67 units of 63 provinces/cities, 22 ministries and political-social organizations and 6 hospitals received funding from TCF to implement a wide range of tobacco control activities. Cessation services have been starting with a a toll-free quit-line but need to be further strengthened. In conclusion, Vietnam has constantly put efforts into the tobacco control field with high commitment from the government, scientists and activists. Though several remarkable achievements have been gained, many challenges remain. To overcome those challenges, implementation strategies that take into account the contextual factors and social determinants of tobacco use in Vietnam are needed.

      • KCI등재

        Outcomes of laparoscopic choledochotomy using cholangioscopy via percutaneous-choledochal tube for the treatment of hepatolithiasis and choledocholithiasis: A preliminary Vietnamese study

        Loi Van Le,Quang Van Vu,Thanh Van Le,Hieu Trung Le,Khue Kim Dang,Tuan Ngoc Vu,Anh Hoang Ngoc Nguyen,Thang Manh Tran 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1

        Backgrounds/Aims: Hepatolithiasis and choledocholithiasis are frequent pathologies and unfortunately, with the current treatment strategies, the recurrence incidence is still high. This study aimed to assess the outcomes of laparoscopic choledochotomy using cholangioscopy via the percutaneous-choledochal tube for the treatment of hepatolithiasis and choledocholithiasis in Vietnamese patients. Methods: A cross-sectional study of patients with hepatolithiasis and/or choledocholithiasis who underwent laparoscopic choledochotomy using intraoperative cholangioscopy via percutaneous-choledochal tube at the Department of Hepatopancreatobiliary Surgery, 108 Military Central Hospital, from June 2017 to March 2020. Results: A total of 84 patients were analyzed. Most patients were females (56.0%) with a median age of 55.56 years. Among them, 41.8% of patients had previous abdominal operations, with 33.4% having choledochotomy. All patients underwent successful laparoscopic common bile duct exploration followed by T-tube drainage without needing to convert to open surgery. Most patients (64.3%) had both intrahepatic and extrahepatic stones. The rate of stones ≥ 10 mm in diameter was 64.3%. Biliary strictures were observed in 19.1% of patients during cholangioscopy. Complete removal of stones was achieved in 54.8% of patients. Intraoperative complications were encountered in two patients, but there was no need to change the strategy. The mean operating time was 121.85 ± 30.47 minutes. The early postoperative complication rate was 9.6%, and all patients were managed conservatively. The residual stones were removed through the T-tube tract by subsequent choledochoscopy in 34/38 patients, so the total success rate was 95.2%. Conclusions: Laparoscopic choledochotomy combined with cholangioscopy through the percutaneous-choledochal tube is a safe and effective strategy for hepatolithiasis and/or choledocholithiasis, even in patients with a previous choledochotomy.

      • SCOPUSKCI등재

        α-Glucosidase Inhibitory Activity of Phenolic Compounds Isolated from the Stems of Caesalpinia decapetala var. japonica

        Le, Thi Thanh,Ha, Manh Tuan,Hoang, Le Minh,Vu, Ngoc Khanh,Kim, Jeong Ah,Min, Byung Sun The Korean Society of Pharmacognosy 2022 Natural Product Sciences Vol.28 No.3

        In our study, sixteen known phenolic compounds, including quercetin (1), methyl gallate (2), caesalpiniaphenol C (3), 8S,8'S,7'R-(-)-lyoniresinol (4), 7,3',5'-trihydroxyflavanone (5), sappanchalcone (6), sappanone A (7), taxifolin (8), fisetin (9), fustin (10), (+)-catechin (11), brazilin (12), 3,4,5-trimethoxyphenyl β-ᴅ-glucopyranoside (13), 1-(2-methylbutyryl)phloroglucinol-glucopyranoside (14), (+)-epi-catechin (15), and astragalin (16) and one mixture of two conformers of protosappanin B (17/18) were isolated from the stems of Caesalpinia decapetala var. japonica. Their structures were elucidated based on a comparison of their physicochemical and spectral data with those of literature. To the best of our knowledge, this represents the first isolation of compounds 3, 4, 8, 9, and 10 from C. decapetala and compounds 13 and 14 from the Caesalpinia genus. All the isolated compounds were evaluated for their inhibitory effect against the α-glucosidase enzyme. Among them, two flavonols (1 and 9), one chalcone (6), and one homoisoflavanone (7) exhibited an inhibitory effect on α-glucosidase action with an IC<sub>50</sub> range value of 5.08-15.01 μM, stronger than that of the positive control (acarbose, IC<sub>50</sub> = 152.22 μM). Kinetic analysis revealed that compounds 1 and 9 showed non-competitive α-glucosidase inhibition, while the inhibition type was mixed for compounds 6 and 7.

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