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한국 밀식사과원의 정지전정에 따른 수체생장과 생산성 및 경영효율 비교
정혜웅,김경훈,송태영,홍성일,한호균,김귀권,신종협,여덕환,김병철,박준권,Jung, H.W.,Kim, K.H.,Song, T.Y.,Hong, S.I.,Han, H.K.,Kim, K.K.,Shin, J.H.,Yeo, D.H.,Kim, B.C.,Park, J.K. 국립한국농수산대학교 교육개발센터 2017 현장농업연구지 = Journal of practical agricultural resear Vol.19 No.1
The present study conducted a comparison on tree growth and productivity of high-density apple orchards by several orchard management systems: making scaffolds by heading-back and thinning out pruning (T-1), maintaining scaffolds upward and bearing shoots downward (T-2), managing branches slightly upward without heading-back (T-3), keeping leaders downward and shoots pending (T-4), maintaining leaders high and branches horizontal with severe pinching (T-5), making leaders with lower branches vigorous and upper shoots pending (T-6), and controlling very high planting density with bending branches (T-7). In conclusion, the orchards of (T-5) and (T-6) management systems showed a superior performance in controlling tree growth, productivity, and quality of fruits. Also, superior management efficiency was obtained in the orchards of (T-5) and (T-6).
RF slice profile effects in magnetic resonance fingerprinting
Hong, T.,Han, D.,Kim, M.O.,Kim, D.H. Pergamon Press 2017 Magnetic resonance imaging Vol.41 No.-
The radio frequency (RF) slice profile effects on T1 and T2 estimation in magnetic resonance fingerprinting (MRF) are investigated with respect to time-bandwidth product (TBW), flip angle (FA) level and field inhomogeneities. Signal evolutions are generated incorporating the non-ideal slice selective excitation process using Bloch simulation and matched to the original dictionary with and without the non-ideal slice profile taken into account. For validation, phantom and in vivo experiments are performed at 3T. Both simulations and experiments results show that T1 and T2 error from non-ideal slice profile increases with increasing FA level, off-resonance, and low TBW values. Therefore, RF slice profile effects should be compensated for accurate determination of the MR parameters.
Shin, H. D.,Park, K. S.,Park, B. L.,Cheong, H. S.,Cho, Y. M.,Lee, H. K.,Lee, J.-Y.,Lee, J.-K.,Kim, H. T.,Han, B. G.,Kim, J. W.,Koh, I.,Kim, Y. J.,Oh, B.,Kimm, K.,Park, C. Blackwell Science Ltd 2006 Diabetic medicine Vol.23 No.1
<P>Abstract</P><P>Aims </P><P>Growing evidence supports the hypothesis that chronic low-grade inflammation related to innate immunity may play an important role in the pathophysiology of Type 2 diabetes mellitus (T2DM). The monocyte differentiation antigen CD14 gene (<I>CD14</I>) acts as the receptor for lipopolysaccharide (LPS) and augments monocyte/macrophage inflammatory responses.</P><P>Methods </P><P>We have sequenced the gene, including all exons, exon/intron boundaries, and the −1.5 kb of the 5′ flanking region. Two common loci (minor allele frequency > 0.05) were genotyped in 775 T2DM patients and 316 control subjects recruited in the Korean T2DM Study.</P><P>Results </P><P>Eight polymorphisms, including four non-synonymous forms, were identified in <I>CD14</I>. No polymorphisms were found in association with T2DM. However, one common promoter SNP (<I>−260T>C</I>) was significantly associated with both the serum triglyceride level (TG) and body mass index (BMI) in non-diabetic control subjects. Individuals who carried the minor allele (C) had higher TG levels (1.65 ± 0.81 vs. 1.46 ± 0.80 mmol/l; <I>P</I> = 0.0007) and BMI (23.96 ± 3.00 vs. 23.28 ± 3.22 kg/m<SUP>2</SUP>; <I>P</I> = 0.04) as compared with subjects carrying T/T genotypes.</P><P>Conclusion </P><P>Our data suggest that lipid metabolism and obesity, important pathophysiological elements of T2DM and the metabolic syndrome, are regulated by complex mechanisms that include the CD14 gene polymorphism-mediated genetic propensity to non-specific inflammatory responses.</P>
Rapid and label-free bioanalytical method of alpha fetoprotein detection using LSPR chip
Kim, D.,Kim, J.,Kwak, C.H.,Heo, N.S.,Oh, S.Y.,Lee, H.,Lee, G.W.,Vilian, A.T.E.,Han, Y.K.,Kim, W.S.,Kim, G.b.,Kwon, S.,Huh, Y.S. North-Holland Pub. Co 2017 Journal of crystal growth Vol.469 No.-
Alpha fetoprotein (AFP) is a cancer marker, particularly for hepatocellular carcinoma. Normal levels of AFP are less than 20ng/mL; however, its levels can reach more than 400ng/mL in patients with HCC. Enzyme linked immunosorbent assay (ELISA) and radioimmunoassay (RIA) have been employed for clinical diagnosis of AFP; however, these methods are time consuming and labor intensive. In this study, we developed a localized surface plasmon resonance (LSPR) based biosensor for simple and rapid detection of AFP. This biosensor consists of a UV-Vis spectrometer, a cuvette cell, and a biosensor chip nanopatterned with gold nanoparticles (AuNPs). In our LSPR biosensor, binding of AFP to the surface of the sensor chip led to an increasing magnitude of the LSPR signals, which was measured by an ultraviolet-visible (UV-Vis) spectrometer. Our LSPR biosensor showed sufficient detectability of AFP at concentrations of 1ng/mL to 1μg/mL. Moreover, the overall procedure for detection of AFP was completed within 20min. This biosensor could also be utilized for a point of care test (POCT) by employing a portable UV-Vis spectrometer. Owing to the simplicity and rapidity of the detection process, our LSPR biosensor is expected to replace traditional diagnostic methods for the early detection of diseases.
Han, T H,Tang, Y,Park, Y H,Maynard, J,Li, P,Akbulut, H,Petersen, L,Deisseroth, A Macmillan Publishers Limited 2010 Bone marrow transplantation Vol.45 No.3
We have developed a vaccine, which is designed to induce tumor-associated antigen (TAA)-specific T cells and antibodies in the setting of profound lymphopenia induced by myeloablative therapy and T-cell-depleted bone marrow transplantation. Test mice were injected subcutaneously (sc) with the 32DP210Bcr-Abl cell line, which is positive for the p210Bcr-Abl protein (Group 1). In Group 2, 7 days after injection of the 32DP210Bcr-Abl positive cell line, the mice received 900 cGy total body irradiation (TBI) followed in 1 h by the intravenous infusion of 10 million T-cell-depleted syngeneic bone marrow cells (TCDBMT) (Group 2). The leukemia-bearing group received an intravenous injection of 10 million spleen cells (donor lymphocyte infusions) from unvaccinated (Group 3) and TAA/ecdCD40L-vaccinated (Group 4) syngeneic mice 3 days after completion of the TBI and TCDBMT. Groups 3 and 4 mice received three additional sc vaccinations at 7-day intervals with the TAA/ecdCD40L vaccine, in which the TAA was taken from the junctional peptide of the P210bcr-Abl protein. The survival of Groups 3 and 4 mice was significantly longer than that in Groups 1 and 2 mice. Vaccinated mice from Group 4, which developed complete responses, survived up to 350 days post-injection of the leukemia cells without any evidence of leukemia regrowth.
대학생들의 건강에 대한 인식 : 의료, 비의료 관련학과를 중심으로
김태영,양지영,이지연,이혜수,조은수,최기쁨,최희원,한보영 이화여자대학교 간호과학대학 2012 이화간호학회지 Vol.- No.46
Purpose: This study has been done to use as basic information for health training program through surveying the perception level for health focusing on medical and non-medical students, and to compare and analyze knowledge, attitude and conduct toward health among them. Method: This study’s investigated by selecting 4 universities in Seoul to look into not only the difference for the perception level for health between medical and non-medical major but the difference of that between male and female. Sampling is 135 of medical-related university and 145 of non-medical. Analyzed by t-test using SPSS 19.0. Result: There isn’t a distinct difference among them in health behavior on the whole but medical-related students showed high score in safety education, environmental health, exercise and individual habit of hygiene. In attitude for health, it showed clear distinction in every areas. Overall, it shows remarkable contrast in knowledge for health. Medical-related students showed high score in consumer health, nutrition, weight-control, exercise and individual habit of hygiene. Conclusion: Results in comparison of the level of living, manner and knowledge level for health between medical and non-medical majors didn’t show any difference in the level of living for health and showed clear distinction in attitude and knowledge.
김태헌(T.H.KIM),김하수(H.S.KIM),한승룡(S.Y.HAN),강희용(H.Y.KANG),양성모(S.M.YANG) 한국자동차공학회 1994 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
In general rear axle for automobiles. which is divided into velocity or power type ratio has been made use of in the same type of engine and T/M.<br/> In the case of either the development of a new automobile or the appropriate alteration of ratio for a new power performance, the precisive estimation through tests of the stability and reliability of rear axle located in the last section of power transmission has been accompanied by the waste of a lot of time and money.<br/> Before this wasteful experimental confirmation a data base can be made with the use of conventional design spec and data, then by the use of which a simulation can be carried out with the variation of design parameters and consequently the results can be applied to the design of a new rear axle.<br/>