효소를 이용한 식물성 식품가공부산물의 식품 소재화 탐색 연구

채희정,한민수,인만진 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.1

이트리아 첨가 붕규산염 유리로 제조한 알루미나-유리 복합체의 강도 평가

채민수,배태성,이주형,원대희,진영철 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.1

This study was performed to investigate the strength of dental alumina-glass composites. Four different brosilicacte glasses containing 1, 3, 6, 9 mol% Y₂O³ were prepared. Alumina compacts were prepared by pressing 150㎏/㎠ and sintering at 1100℃ for 2 hours. Dense composites were made by infiltrating partially sintered alumina with at 1200℃ for 6 hours. The obtained results were summarized as follows: 1. With increasing the amount of Y₂O₃ the peak of exothermic heat and softening point were shifted to the higher temperature. 2. Borosilicate glasses showed the coefficient of thermal expansion in the range of 6.36 to 6.56×10-6/℃. 3. The maximum biaxial strength of 385.7±34.4MPa was obtained with an addition of 6mol% Y₂O₃. 4. The observation of fracture surfaces showed the crack deflection and crack bridging and that appeared to be the principal strengthening mechanism in the alumina-glass composites.

明代後期關於角色體驗的戱曲表演論

蔡守民 中國語文硏究會 2002 中國語文論叢 Vol.22 No.-

명대 壽靖시기에 魏良輔가 昆山腔을 개량한 이후, 곤곡은 문인을 위시한 많은 관중들의 사랑을 받게 되고, 이와함께 희곡 공연도 흥성하였다. 희곡공연예술의 번성은 공연예술이론의 발전을 가져와, 明 後期에 이르면 희곡이론가들은 이전과 달리 淸唱의 연장이 아닌 하나의 연극으로서 희곡공연을 이식하고 희곡공연이론을 제기하게 된다. 이 공연이론 중에서 주의할 만한 것은 배우와 배역의 관계에 관한 연기이론으로, 탕현조, 반지항 등 명 후기 희곡이론가들은 배우가 그 맡은 배역 인물을 얼마나 잘 형상화해내는 가에 관심을 가졌으며, 특히 극중 인물의 감정을 정확히 체험하고 표현해낼 것을 주장하였다. 이들은 성공적인 배역 형상화의 관건이 극본의 주제사상 파악과 극중 인물에 대한 정확한 분석 등에 있다고 보고, 먼저 극본을 정확하게 이해할 것을 강조하였다. 또 극중인물의 형상화에 있어서는 "以情寫情" 즉 배역인물의 사상과 감정을 정확하게 체험하고 전달하는 것이 무엇보다 중요하다 여겼다. 明後期 희곡이론가들이 극본의 정확한 이해를 통한 배역의 감정에 대한 충분한 체험을 주장한 것은, 배우와 배역의 관계에 있어 배우가 무대 위에서 배역에 대한 體驗을 정확하게 體現해낼 것을 강조하는 중국희곡 연기이론 수립에 기본적인 틀을 제공한 것이다.

광중합형 수복용 복합레진의 인장강도에 미치는 thermal cycling과 시효 처리의 영향

백상현,채민수,이주형,김태조,배태성 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.1

The improvement in the mechanical properties of restorative composites has contributed to their increased use in recent years. In spite of their growing popularity, composites still have low resistance to fracture and wear in oral environments. This study was performed to examine whether the tensile strengths of light-cured restorative composites were affected by thermal cycling and aging in water. Five commerically available light-activated composites(Heliomolar : HM, Aelitefil : AF, Amelogen : AG, Clearfil AP-X : CF, Z100 : ZH) were used. Rectangular tension test specimens were fabricated in a teflon mold giving 5 mm in gauge length and 2mm in thickness. All samples were divided into 3 groups. Group 1 was stored in a desiccator for 10 days. Group 2 was immersed in a 37℃ distilled water for 10 days. Group 3 was subjected to 10,000 thermal cycles between 5℃ and 55℃, and the immersion time in each bath was 15 seconds per cycle. Tensile testing was carried out at a crosshead speed of 0.5 mm/min and fracture surfaces were observed with scanning electron microscope. The results obtained were summarized as follows; 1. The strength data fit to single-mode Weibull distribution(r²> 0.86) and Weibull parameters decreased after thermal cycling test. 2. The highest characteristics strength was observed in the CF group but the highest Weibull modulus was obtained in the AF group after thermal cycling test. 3. The highest tensile strength value of 83.92 MPa was obtained in the CF group and the lowest value of 13.91 MPa was obtained in the AG group. Tensile strengths showed no significant difference between HM and AG groups but other groups showed the significant differences in each group(p<0.05). 4. According to the microscopic observation of the fracture surfaces, fractures of large fillers were observed in the hybrid composites of the AF and CF groups.

광중합형 수복용 복합레진의 강도에 미치는 Thermal Cycling의 영향

백상현,채민수,배태성 대한치과기재학회 1996 대한치과재료학회지 Vol.23 No.1

This study was performed to investigate the effects of thermal cycling on the strength of light cured restorative composite resins. Five commerically available light-activated composite resins(Photo Clearfil A : CA. Lite-Fil A : LF, Clearfil Photo Posterior : CP, Prisma AP.H. : PA, Z100 : ZH) were used. The specimens of 12mm in diameter and 0.7mm in thickness were made, and a thermal cycling test of 1000 cycles at 15 seconds dwell time each in 5℃ and 55℃ baths was performed. In order to investigate the deterioration of composite resins in the thermal cycling test, the bi-axial flexure strengths were measured, and the surface after thermal cycling test were examined by SEM. The results obtained were summarized as follows; 1. Biaxial flexure strength significantly decreased due to the thermal cycling(P<0.01). 2. Biaxial flexure strengths showed the maximum value of 125.65MPa for ZH group and the minimum value of 64.86MPa for ZA group, after thermal cycling test, Biaxial fleure strengths of ZH and CP group were higher then those of PA, CF, and CA groups after thermal cycling test(p<0.05). 3. Fracture surfaces showed that the composite resin failure developed along the matrix and the filler/resin interface region, and the cracks propagated in the conical shape from the maximum tensile stress zone.

광중합형 복합레진 제조시의 압축강도에 관한 실험적 연구

배태성,추용호,채민수 大韓齒科器材學會 1995 대한치과재료학회지 Vol.22 No.2

This study was performed to elaluate the effect of matrix resins and fillers on the compressive strength of light-activated composite resins. Four different types of composites were made by mixing the inorganic fillers of armorphous spherical silica and crushed quartz with resins of BisGMA/TEGDMA and UTeMA/TEGDMA. The specimens of 3mm in diameter and 6mm in length were prepared. Compressive test was subjected to a crosshead speed of 0.5mm/min and fracture surfaces were examined by SEM. The results obtained were summarized as follows; 1. Compressive strength of the UTeMA-based composite resin with spherical filler was superior to the other composite resins(p<0.01). 2. Compressive strength of the BisGMA-based composite resins with significantly decreased after immersion in water for 7 days(p<0.05). 3. UTeMA-based composite resins showed the aspect of decrease in compressive strength after cold storage at 5℃.

필러의 종류가 UTMA 계 광중합형 복합레진의 강도에 미치는 영향

배태성,최진용,최규형,채민수 大韓齒科器材學會 2000 대한치과재료학회지 Vol.27 No.3

This study was performed to evaluate the effect of resin and filler type on the strength of light-activated composites. Experimental composites were prepared using the four types of urethane tetramethacrylate monomers(HM-4M, TM-4M, XY-4M and DC-4M) and three different shapes of silica fillers. Cylindrical specimens of 3㎜ in diameter and 6㎜ in length and rectangular specimens of 2×2×24㎜ were prepared for the compressive test and 3-point bend test, respectively. All specimens were immersed in distilled water at 37℃ for 24 hours. Compressive and 3-point bend tests were carried out at a crosshead speed of 0.5 ㎜/min and fracture surfaces were observed with scanning electron microscope. The results obtained were summarized as follows : 1. When the size distribution of fillers was same, composites containing the spherical fillers showed the relatively higher loading rate of fillers and compressive strength than those containing the crushed fillers. 2. Compressive strength values of the composites based on UTMA monomers containing the aliphatic UTMA monomers (HM-4M and TM-4M) showed the relatively higher strength values than those of the composites based on UTMA monomers containing the aromatic or cyclohexane ring in their chemical structure(XY-4M and DC-4M). 3. The compressive and transverse strength values of UTMA-based composites were higher than those of Bis-GMA-based composites. 4. According to the microscopic observation of fracture surfaces, composite failure developed along the matrix resin and resin/filler interface region.

상피종양의 keratin 생성능에 대한 전자현미경적 연구

이길선,이명주,장정수,이민전,노광을,서재홍 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Keratins are characteristically present in all keratinizing and nonkeratinizing epithelial cells and their neoplasms. They consist of at least 19 different polypeptides ranging from 40 to 69 kilodaltons, which are developmentally related to specific epithelial cell types. Keratins of high and intermediate molecular weights are readily demonstrated in squamous cell carcinomas, which are characteristically rich in tonofilaments and tonofilament-desmosome complexes. Keratins of low molecular weights are expressed in adenocarcinoma including renal cell carinoma, hepatocellular carcinoma, small cell carcinoma, and carcinoid tumor. These tumors do not reveal any tonofilaments and sacrcely show discrete filaments on electron microscopy. An immunoperoxidase technique employing antibody to keratin was used to study distribution and staining pattern of keratin filaments in benign and malignant epithelial tumors (20 squamous cell carcinomas, 20 gastric adenocarcinomas, 20 transitional cell carcinomas and 15 non-neoplastic epithelia). These immunohistochemical results were compared with ultrastructural features of neoplastic diagnosis of squamous cell carcinoma, adenocarcinoma and transitional cell carcinoma, and estimation of degree of differentiation. The results are as follows : 1. The squamous epithelium, glandular epithelium and transitional epithelium disclosed the positive reaction for keratin. 2. Squamous cell carcinoma and transitional cell carcinoma exhibited positive reaction for keratin. 3. Gastric adenocarcinoma showed uniformly negative or weakly positive reaction for keratin. 4. On electron microscopy, heavy bundles of tonofilaments and desmosomes were more frequently encountered in well differentiated squamous cell carcinoma, In poorly differentiated squamous cell carcinoma, a few tonofibrils and desmosome were noted. 5. In the adenocarcinomas, the intermediate filaments were arranged randomly as nonaggregated, short filaments spread throughout the cytoplasm, although occasionally they formed a perinuclear whorl. These filaments did not become aggregated to form tonofilaments. 6. On the immunogold labeling for keratin of low molecular weight areas in gastric adenocinoma, in tense labeling of intermediate filaments for keratin was noted. From the above result, ultrastructural and immunohistochemical study on malignant epithelial cell were useful in differential diagnosis of squamous cell carcinoma, adenocarcinoma and transitional cell carcinoma, and estimation of degree of differentiation. It was also proved that immunogold labeling technique was especially valuable for diagnosis of vague case which showed negative or weakly positive reaction in immunohistochemical stain.

고농도 산소 공급이 노인의 인지 능력과 혈중 산소 포화도에 미치는 영향

김지혜(Ji-Hye Kim),신채호(Chae-Ho Shin),최윤정(Yoon-Jeong Choi),최미현(Mi-Hyun Choi),이수정(Su-Jeong Lee),양재웅(Jae-Woong Yang),민병찬(Byung-Chan Min),박세진(Se-Jin Park),정순철(Soon-Cheol Chung) 대한인간공학회 2010 대한인간공학회 학술대회논문집 Vol.2010 No.10

This study investigated changes in cognitive task performance and blood oxygen saturation (SpO2) of old people when the concentration and supply rate of oxygen administration were varied (21% (1L/min), 93% (1L/min), and 93% (5L/min)). It recruited totally 20 elderly subjects including 9 males (75.1±4.2 years) and 11 females (73.1±4.3 years). The experiment consisted of 1-back task performed under three conditions (21% (1L/min), 93% (1L/min), and 93% (5L/min)). Each run consisted of three phases: Adaptation of oxygen administration (3 min), Control (2 min), and 1-bak task (2 min). SpO2 [%] was measured during each phase. Higher concentration and supply rate of oxygen administration were associated with more pronounced increase in SpO2 and decrease in response time of 1-back task.

Regulation of Interferon Stimulated Genes (ISG)-12, 15, and MX1 and MX2 by Conceptus Interferons (IFNTs) in Bovine Uterine Epithelial Cells

Min-Su Kim,Chae-Won Park,Tsevelmaa Nanjidsuren,Eun-Bi Seo,Kazuhiko Imakawa,Kwan-Sik Min 한국동물생명공학회(구 한국동물번식학회) 2013 Reproductive & Developmental Biology(Supplement) Vol.37 No.2s