3분과 : 가선집재작업에서의 작업 생산성 및 비용 분석

한원성 ( Won Sung Han ),한한섭 ( Han Sup Han ),김남훈 ( Nam Hun Kim ),차두송 ( Du Song Chu ),조구현 ( Koo Hyun Cho ),민도홍 ( Do Hong Min ),권기철 ( Ki Cheol Kwon ) 한국임학회 2014 한국산림과학회지 Vol.103 No.1

본 연구에서는 임목수확작업에 사용되는 집재기계의 작업효율성을 분석하여 경사가 급한(20° 이상) 작업조건에 적합한 가선계 집재기계를 선정하는데 기초 정보를 제공하고자, 타워야더(RME-300T), 트랙터부착형 집재기(일명: 춘천집재기), 트랙터윈치(FARMI) 등에 의한 집재작업에서의 작업생산성 및 비용을 비교 분석하였다. 평균 흉고직경이 20 cm, 집재거리 60 m, 가로집재거리 10 m, 그리고 기계이용률이 70%인 동일한 작업 조건에서 작업이 이루어질 경우, 타워야더의 1일 집재작업 생산성은 33.04 m3/일, 트랙터부착형 집재기는 38.47 m3/일, 그리고 트랙터윈치는 14.17 m3/일으로 분석되었으며, 이에 따른 집재작업비용은 각각 25,105원/m3, 20,520원/m3, 37,835원/m3으로 나타났다. 동일한 작업조건에서 집재거리에 따른 각 집재기계별 작업효율성을 비교하였을 경우, 집재거리가 40 m 이내로 짧을 경우에는 트랙터윈치에 의한 집재작업이 효율적이며, 40~140 m의 집재거리에서는 춘천집재기가, 140 m 이상의 장거리 집재작업에서는 타워야더가 가장 효율적인 것으로 나타났다. This study was conducted to provide field-based harvesting study information which can be used to select an optimal cable system for certain work conditions on steep grounds (>20° ground slope) in Korea. Toaccomplish this study objectives, we evaluated three cable yarding systems (RME-300T tower-yarder, Chuncheontower-yarder, FARMI tractor winch) working in typical work conditions for their yarding productivity and operational efficiency. Those yarders are commonly used for removing logs or trees on steep grounds in Korea. Under the same work conditions (average DBH of tree to be cut, 20 cm; yarding distance, 60 m; lateral yardingdistance, 10 m; and machine utilization rate, 70%), the average productivities were 33.04 m3/day, 38.47 m3/day, and 14.17 m3/day for RME-300T, Chuncheon tower-yarder, and FARMI, respectively. Our standardized cost comparison study also showed that the yarding cost was highest at 37,835 won/m3 with FARMI, followed byRME-300T at 25,105 won/m3 for the same work conditions. We found the lowest yarding cost with the Chuncheon tower-yarder at 20,520 won/m3 which was resulted primarily from high yarding productivity at theyarding distance (60 m). Our analysis suggested that a small machine such as FARMI could be a low-costyarding machine option for a cable yarding job with a short yarding distance (40 m or less). The Chuncheontower-yarder is well suited for a mid-range yarding distance job in Korea, ranged between 40 to 140 m. Ifyarding distance were longer than 140 m, the RME-300T tower yarder appears to be most cost-effective.

석탄 가스화를 통한 전력 생산과 DME 병산 공정에 대한 기초 경제성 분석

유영돈 ( Young Don Yoo ),김수현 ( Su Hyun Kim ),조원준 ( Won Jun Cho ),모용기 ( Yong Gi Mo ),송용택 ( Tae Kyong Song ) 한국화학공학회 2014 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.52 No.6

석탄가스화를 기반으로 한 발전(IGCC 발전) 및 화학원료 제조공정의 상업화 관건은 화석연료인 원유 또는 천연가스를 기반으로 생산되는 경우와 비교하여 경제성을 확보할 수 있는지 여부이다. 경제성 확보를 위한 가장 현실적인 방법으로는 석탄 가스화를 통해 얻어진 합성가스로부터 2개 이상의 생산물(예: 발전과 화학원료를 동시 생산)을 병산(coproduction또는 poly-generation)하는 것이다. 본 연구에서는 석탄 가스화를 기반으로 하여 발전과 수송용, 발전용 및 가정용 연료로 사용이 가능한 DME(dimethyl ether)를 병산하는 공정에 대한 경제성 분석을 실시하였다. 경제성 분석을 위한 병산 공정에서는 250 MW 전력생산 연간 30만 톤의 DMZ 생산을 기준으로 하였다. 병산 공정에서 DME 판매가격이 50만원/ton인 경우, 전기 생산원가는 34.8~58.4원/kWh으로 SMP(계통한계가격) 가중평균인 150.69원/kwh(2013년 1월~12월까지의 평균값)의 33~58% 수준으로 산정되었다. 따라서, DME 판매가격이 적정하게 유지될 경우 석탄IGCC+DME 병산공정은 IGCC 단독 발전과 비교하여 경제성을 확보할 수 있을 것으로 판단된다. 현재 중국에서 DME판매가격이 900,000원/톤 내외이므로, 전력과 DME를 병산할 경우, IGCC 단독으로 전력을 생산할 경우와 비교하여 전력 생산 원가를 월등하게 낮출 수 있음을 알 수 있다. 이와 같이 석탄 가스화를 기반으로 한 병산 공정을 통해 전력과 DME를 병산하는 시스템에서, 시장 여건에 따라 전력과 DME 생산비율 제어가 가능하고, 석탄 가스화기 및 정제 시스템을 공통 설비로 활용함으로써, 개별적으로 생산하는 것보다 생산 원가를 낮출 수 있다는 결과를 얻었다. The key for the commercial deployment of IGCC power plants or chemical (methanol, dimethyl ether, etc.) production plants based on coal gasification is their economic advantage over plants producing electricity or chemicals from crude oil or natural gas. The better economy of coal gasification based plants can be obtained by co-production of electricity and chemicals. In this study, we carried out the economic feasibility analysis on the process of co-producing electricity and DME (dimethyl ether) using coal gasification. The plant’s capacity was 250 MW electric and DME production of 300,000 ton per year. Assuming that the sales price of DME is 500,000 won/ton, the production cost of electricity is in the range of 33~58% of 150.69 won/kwh which is the average of SMP (system marginal price) in 2013, Korea. At present, the sales price of DME in China is approximately 900,000 won/ton. Therefore, there are more potential for lowering the price of co-produced electricity when comparing that from IGCC only. Since the co-production system can not only use the coal gasifier and the gas purification process as a common facility but also can control production rates of electricity and DME depending on the market demand, the production cost of electricity and DME can be significantly reduced compared to the process of producing electricity or DME separately.

FCT 5 : Fractional laser-assisted topical imiquimod 5% cream treatment for recalcitrant common warts in children

( Hyun Chang Ko ),( Jeong Min Kim ),( Hyun Ho Cho1 ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Conventional destructive modalities for warts like cryotherapy or laser ablation have some limitations that are excruciating pain during procedure, in especially pediatric patients. Imiquimod is a topical immune response modifier that was approved for treating genital and perianal warts. But, thick stratum corneum of common warts may act as a barrier against drug permeation via the skin. Objectives: To evaluate efficacy and safety of above treatment. Methods: Eleven pediatric patients (6 female and 5 male, mean age 12.5 years) were included in this study. The lesions were treated by fractional 2940 nm Er:YAG laser for achieving the penetration of stratum corneum with 1 or 2 weeks intervals. Then, imiquimod 5% cream was self-applied once daily for 5 days a week. Assessment of response and adverse effects was performed every 2 weeks until complete clearance or up to maximum of 48 weeks. Pain during procedure was checked by VAS (0-10). Results: 8 out of 11 (72.7%) patients experienced complete clearance of all warts lesions. Mean duration of total treatment was 29.7 (16-48) weeks. Mean number of fractional laser treatment was 17.5 (8-37) times. No significant adverse effect was observed. VAS score of the pain during fractional laser treatment was 2.4 (1-4), comparing with 6.2 (5-8) during cryotherapy. Conclusion: Fractional ErYAG laser-assisted topical 5% imiquimod cream is an effective and safe treatment option for recalcitrant common warts of the children do not tolerate pain well.

Pollen Viability of Common Buckwheat (Fagopyrum esculentum Moench.) in in vitro Germination and its Application to Male Gametophyte Isolation

Woo, Sun-HeeㆍKeun-Yook ChungㆍHeung-Tae, KimㆍYong-Gu, ChoㆍHong-Sig, KimㆍBeom-Heon, Songㆍ Chul-Won, Lee and Seung-Keun Jong 忠北大學校 農業科學硏究所 2004 農業科學硏究 Vol.21 No.-

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Cucurbitacin B suppresses adipocyte differentiation through inhibition of STAT3 signaling

Cho-Rong Seo,No-Joon Song,Woo-Seok Jang,Kye Won Park 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

Relationship between ganglioside expression and anti-cancer effects of a plant-derived antibody in breast cancer cells

Won Seok Ju,Ilchan Song,Se-Ra Park,Sang Young Seo,Jin Hyoung Cho,Sung-Hun Min,Dae-Heon Kim,Ji-Su Kim,Sun-Uk Kim,Soon Ju Park,Kisung Ko,Young-Kug Choo 한국식물생명공학회 2019 JOURNAL OF PLANT BIOTECHNOLOGY Vol.46 No.3

Production of therapeutic monoclonal antibodies (mAbs) using a plant platform has been considered an alternative to the mammalian cell-based production system. A plant-derived mAb CO17-1AK (mAbP COK) can specifically bind to various types of cancer cell lines. The target protein of mAbP COK is the epithelial cell adhesion molecule (EpCAM) highly expressed in human epithelial cancer cells, including breast and colorectal cancer cells. It has been hypothesized that its overexpression supports tumor growth and metastasis. A ganglioside is extended well beyond the surfaces of the various cell membranes and has roles in cell growth, inflammation, differentiation, and carcinogenesis. However, the regulation of EpCAM gene expression in breast cancers and the role of gangliosides in oncogenesis are unclear. Here, the purpose of this study was to determine the effects of mAbP COK on human breast cancer cell proliferation, apoptosis, and ganglioside expression patterns. Our results show that treatment with mAbP COK suppressed the growth of breast cancer cells and induced apoptotic cell death. It also upregulated the expression of metastasis-related gangliosides in breast cancer cells. Thus, treatment with mAbP COK may have chemo-preventive therapeutic effects against human breast cancer.

Evaluation of the carbon dioxide (CO₂) emission factor from lime applied in temperate upland soil

Cho, Song Rae,Jeong, Seung Tak,Kim, Gun Yeob,Lee, Jeong Gu,Kim, Pil Joo,Kim, Gil Won Elsevier 2019 Geoderma Vol.337 No.-

<P><B>Abstract</B></P> <P>Agricultural liming materials are broadly utilized in the world to ameliorate soil acidity. Crushed limestone (CaCO<SUB>3</SUB>) and dolomite (MgCO<SUB>3</SUB>·CaCO<SUB>3</SUB>) are most common liming materials. The CO<SUB>2</SUB> emission coefficient was proposed as 0.12 Mg C per Mg for CaCO<SUB>3</SUB> by the Intergovernmental Panel on Climate Change (IPCC), which indicates that 100% of C in CaCO<SUB>3</SUB> is eventually released to the atmosphere in the form of CO<SUB>2</SUB>. However, this assumption appears unlikely based on current knowledge of the very low solubility of CaCO<SUB>3</SUB> and carbonate transport through soil. To develop the direct CO<SUB>2</SUB> emission factor from the C-containing liming materials applied in moderately acidic soil, CaCO<SUB>3</SUB> was applied in a typical temperate upland soil at different levels (0–2 Mg ha<SUP>−1</SUP> yr<SUP>−1</SUP>), and the CO<SUB>2</SUB> emission rates were determined using the closed chamber method for two years. The direct CO<SUB>2</SUB> emission factor from CaCO<SUB>3</SUB> was estimated using <SUP>13</SUP>CO<SUB>2</SUB> fluxes from <SUP>13</SUP>C-CaCO<SUB>3</SUB> applied soils. Approximately 0.026 Mg C per Mg of CaCO<SUB>3</SUB> was emitted as CO<SUB>2</SUB> from CaCO<SUB>3</SUB> in cropping lands. This value was much lower than the IPCC default value (0.12 Mg C per Mg of CaCO<SUB>3</SUB>). The current CO<SUB>2</SUB> emission coefficient was comparable with the United States Environmental Protection Agency (EPA) emission factor (0.046 Mg C per Mg of CaCO<SUB>3</SUB>) from the agricultural field. If the EPA emission factor from the ocean (0.013 Mg C per Mg of CaCO<SUB>3</SUB>) is added to the currently developed CO<SUB>2</SUB> emission factor of the inner agricultural field, the total CO<SUB>2</SUB> emission factor from lime may be close to 0.039 Mg C per Mg of CaCO<SUB>3</SUB> in the selected upland soil. Therefore, we propose that the current IPCC guideline value of the CO<SUB>2</SUB> emission factor from lime should be revised as 0.039 Mg C per Mg of CaCO<SUB>3</SUB> for Korean upland soils.</P> <P><B>Highlights</B></P> <P> <UL> <LI> IPCC proposed 0.12 Mg CO<SUB>2</SUB>-C per Mg CaCO<SUB>3</SUB> as the CO<SUB>2</SUB> emission factor from CaCO<SUB>3</SUB> in soil. </LI> <LI> 0.026 Mg CO<SUB>2</SUB>-C per Mg CaCO<SUB>3</SUB> was emitted from CaCO<SUB>3</SUB> during maize cultivation. </LI> <LI> EPA estimated 0.013 Mg CO<SUB>2</SUB>-C per Mg CaCO<SUB>3</SUB> of CO<SUB>2</SUB> emission factor released from agricultural field. </LI> <LI> CO<SUB>2</SUB> emission factor of CaCO<SUB>3</SUB> should be revised with 0.039 Mg CO<SUB>2</SUB>-C per Mg CaCO<SUB>3</SUB> in Korean upland soil. </LI> </UL> </P>

A Study on Soil Suitability Criteria for Liriopis Platyphylla

Cho, Hyun-Jun,Hyun, Byung-Keun,Sonn, Yeon-Kyu,Park, Chan-Won,Chun, Hyen-Chung,Song, Kwan-Cheol,Noh, Dae-Cheol,Yun, Kwan-Hee 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6

Soil properties and yields of liriopis platyphylla were investigated to establish soil suitability of Korean liriopis platyphylla at 116 farms in Korea. Morphological and physical properties of the soils were investigated along with the average yield of 2~3 years. The impact factors of soil properties to the yield of liriopis platyphylla were selected based on standard error of each factor. The yields of liriopis platyphylla showed the greatest values when the morphology was alluvial plains, when the drainage was well or moderately well, when the slope was 0-2%, the texture was coarse loamy, when the gravel content was less than 15% and when the available soil depth was more than 100 cm. Contribution factors of soil properties to the yields were 0.15 by morphology, 0.15 by drainage level, 0.13 by slope, 0.18 by texture, 0.16 by gravel content and 0.23 by available soil depth, respectively. Soil suitability classes were set as follows; the best suitable land if score was greater than 92, suitable land if score ranged from 91 to 86, the possible land if the score ranged from 85 to 83, and low productive land if score was less than 82. According to the criteria, 17.8% of the production area was the best suitable land, 43.1% was suitable land, 17.3% was possible land, and 21.8% was low productive land. The sum of both the best and suitable lands were 60.9% of the farm area of Miryang in Gyeongsangnam-do.

Inhibitory Effect of Proanthocyanidin on Ultraviolet B Irradiation-Induced Melanogenesis

Cho, Ho-Song,Kwak, Dong Hoon,Choi, Im Seup,Park, Hyung Kook,Kang, Sang Jin,Yoo, Hwan Soo,Lee, Moon Soon,Oh, Ki-Won,Hong, Jin Tae Informa UK (TaylorFrancis) 2009 Journal of toxicology and environmental health. Pa Vol.72 No.21

<P>Repetitive exposure of the skin to ultraviolet (UV) radiation induces various adverse effects, including skin thickening, wrinkle formation, inflammation, and pigmentation. Various natural and synthetic compounds were studied to determine whether they might prevent UV induction of these adverse effects. In particular, naturally occurring antioxidants were used for regulating skin damage induced by UV radiation since several antioxidants were found to inhibit photoaging through prevention of collagen synthesis via inhibition of matrix metalloproteinases (MMP) and/or decrease of melanin synthesis. The L values in pigmented skin were lower at 4 wk (52.97 +/- 2.09) than at the start of this study (0 wk, 62.89 +/- 0.56) in the control. In the proanthocyanidin mixture group, the L value was increased (56.83 +/- 1.71) similar to the control (52.97 +/- 2.09). Proanthocyanidin also suppressed the expression levels of tyrosinase by 20-40%, and blocked the expression of MITF, TRP-1, and TRP-2, which are factors implicated in the control of melanogenesis. Taken together, these data indicate that proanthocyanidin may be useful to attenuate UVB-induced melanogenesis.</P>

Validation of tissue-specific promoter-driven tumor-targeting trans-splicing ribozyme system as a multifunctional cancer gene therapy device in vivo

Song, M-S,Jeong, J-S,Ban, G,Lee, J-H,Won, Y-S,Cho, K-S,Kim, I-H,Lee, S-W Nature Publishing Group 2009 Cancer gene therapy Vol.16 No.2

A trans-splicing ribozyme that can specifically reprogram human telomerase reverse transcriptase (hTERT) RNA was previously suggested as a useful tool for tumor-targeted gene therapy. In this study, we applied transcriptional targeting with the RNA replacement approach to target liver cancer cells by combining a liver-selective promoter with an hTERT-mediated cancer-specific ribozyme. To validate effects of this system in vivo, we constructed an adenovirus encoding for the hTERT-targeting trans-splicing ribozyme under the control of a liver-selective phosphoenolpyruvate carboxykinase promoter. We observed that intratumoral injection of this virus produced selective and efficient regression of tumors that had been subcutaneously inoculated with hTERT-positive liver cancer cells in mice. Importantly, the trans-splicing reaction worked equally well in a nude mouse model of hepatocarcinoma-derived peritoneal carcinomatosis, inducing the highly specific expression of a transgene, and moreover, the efficient regression of the hTERT-positive liver tumors with minimal liver toxicity when systemically delivered with the adenovirus. In addition to the observed hTERT-dependent therapeutic gene induction, significant reductions in the levels of hTERT RNA (∼75%) were also observed. In conclusion, this study demonstrates that a cancer-specific RNA replacement approach using trans-splicing ribozyme with a tissue-selective promoter represents a promising strategy for cancer treatment.Cancer Gene Therapy (2009) 16, 113–125; doi:10.1038/cgt.2008.64; published online 29 August 2008