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- 저자 : Song Xing (검색결과 94 건)
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Effects of SRBSDV-infected rice plants on the fitness of vector and non-vector rice planthoppers
Hong-Xing Xu,Hong-Xing Xu,Xu-Song Zheng,Yajun Yang,Jue-Feng Zhang Zhang,Zhong-Xian Lu 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.3
Southern rice black-streaked dwarf virus (SRBSDV) is a new member of the genus Fijivirus and transmitted by whitebacked planthopper (WBPH), Sogatella furcifera (Horváth). The rice area affected by SRBSDV and the subsequent damages are increasing rapidly. In current study, we evaluated the effects of SRBSDV-infected plants on the ecological fitness and the tolerance to adverse environmental factors of vector WBPH and non-vector brown planthopper (BPH), Nilaparvata lugens (Stål). Our study revealed that the fitness of WBPH and BPH were both influenced by feeding on SRBSDV-infected rice. Fecundity ofWBPH feeding on the SRBSDV-infected rice plants were higher than those on healthy plants, nymphal duration of male WBPH prolonged markedly by 0.77 d (P b 0.05), while the weight of brachypterous female adults significantly decreased (P b 0.05), and the average survival time shortened both at 26 °C and 31 °C, respectively. Median lethal time of WBPH on SRBSDV-infected and healthy rice plants were 80 h and 112 h at 26 °C, 64 h and 88 h at 31 °C, respectively. As for non-vector BPH, nymph survival rate decreased significantly by 11.22% (P b 0.05) and the longevity of female adults also shortened (P b 0.05), while hatchability of BPH eggs increased (P b 0.05). Survival time of BPH feeding on healthy rice at 26 °Cwas significant longer than those feeding on healthy and infected rice at 31 °C. The above results imply that the vectorWBPH suffers much stronger effects than non-vector BPH fromfeeding on SRBSDVinfected rice plants.
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Identification of Specific Gene Modules in Mouse Lung Tissue Exposed to Cigarette Smoke
Xing, Yong-Hua,Zhang, Jun-Ling,Lu, Lu,Li, De-Guan,Wang, Yue-Ying,Huang, Song,Li, Cheng-Cheng,Zhang, Zhu-Bo,Li, Jian-Guo,Xu, Guo-Shun,Meng, Ai-Min Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10
Background: Exposure to cigarette may affect human health and increase risk of a wide range of diseases including pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), asthma, lung fibrosis and lung cancer. However, the molecular mechanisms of pathogenesis induced by cigarettes still remain obscure even with extensive studies. With systemic view, we attempted to identify the specific gene modules that might relate to injury caused by cigarette smoke and identify hub genes for potential therapeutic targets or biomarkers from specific gene modules. Materials and Methods: The dataset GSE18344 was downloaded from the Gene Expression Omnibus (GEO) and divided into mouse cigarette smoke exposure and control groups. Subsequently, weighted gene co-expression network analysis (WGCNA) was used to construct a gene co-expression network for each group and detected specific gene modules of cigarette smoke exposure by comparison. Results: A total of ten specific gene modules were identified only in the cigarette smoke exposure group but not in the control group. Seven hub genes were identified as well, including Fip1l1, Anp32a, Acsl4, Evl, Sdc1, Arap3 and Cd52. Conclusions: Specific gene modules may provide better understanding of molecular mechanisms, and hub genes are potential candidates of therapeutic targets that may possible improve development of novel treatment approaches.
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Lenalidomide in Treating Patients with Castration-Resistant Prostate Cancer
Xing, Dong-Liang,Song, Dong-Kui,Zhang, Li-Rong Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Background: This analysis was conducted to evaluate the efficacy and safety of lenalidomide based regimen in treating patients with castration-resistant prostate cancer. Materials and Methods: Clinical studies evaluating the efficacy and safety of lenalidomide based regimens on response and safety for patients with castration-resistant prostate cancer were identified using a predefined search strategy. A pooled response rate (rate of PSA level decline of ${\geq}50%$) to treatment was calculated. Results: In lenalidomide based regimen, 3 clinical studies which including 98 patients with castration-resistant prostate cancer were considered eligible for inclusion. These lenalidomide based regimens included cisplatin, doxorubicin, or GM-CSF. Pooled analysis suggested that, in all patients, the pooled PSA level decline of ${\geq}50%$ was 13.3% (13/98) in lenalidomide based regimens. Fatigue, nausea and vomitting were the main side effects. No grade III or IV renal or liver toxicity were observed. No treatment related death occurred in patients with lenalidomide based regimens. Conclusions: This evidence based analysis suggests that lenalidomide based regimens are associated with mild response rate and acceptable toxicities for treating patients with castration-resistant prostate cancer.
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Xing Fan,Jisu Seo,YueLin Li,Ahyun Ryu,Kyoungok Joo,Moonkyoung Park,Rhayun Song 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10
Aim(s): Physical and cognitive functioning are both indicators of aging process. Older adults experience abnormal declines in physical and cognitive functioning that increase their risk of dependence, subsequently quality of life. This study aims to explore the relationship between physical and cognitive functioning, and mediation effect of cognitive functioning on the relationship of physical functioning and health-related quality of life among older adults with mild cognitive impairment. Method(s): Seventy-nine older adults living in community participated in the study. Measurements included the self-reported questionnaire for physical functioning consisted of grip strength, one leg standing with eyes open (balance), and Timed Up and Go (mobility). Cognitive functioning was measured by Korean version of MOCA. SF-12 was used to assess physical and psychological components of quality of life (QOL). Data were using multiple regression and a simple mediation model applying the PROCESS macro for mediation. Result(s): Physical functioning explained 14.5% of variance in cognitive functioning. Physical and cognitive functioning together explained 22.4% of variance in physical component of QOL, 18.7% of variance in mental component of QOL. Indicators of physical functioning significantly related with cognitive functioning with balance (B=0.41, p=.02). Cognitive functioning had significant indirect effects B= 0.19, 95%CI (.491~.008) between balance and physical component of QOL, while the indirect effects was not significant with mental component of QOL (B=0.06, 95%CI -.107~0.332). Conclusion(s): The findings showed cognitive functioning had a significant mediating effects between the physical functioning and physical components of QOL. These findings have suggested that nursing intervention to improve physical functioning such as balance, mobility and grip strength may also improve cognitive functioning, consequently improving physical component of QOL for older adults with mild cognitive impairment. Further studies are warranted to explore the effects of health promotion programs designed to enhance physical and cognitive functioning in this population.
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Estimating Mobile-Friendliness Scores of Web Pages
SONG, Jihwan,XIE, Xing,LEE, Yoon-Joon,WEN, Ji-Rong The Institute of Electronics, Information and Comm 2010 IEICE transactions on information and systems Vol.93 No.11
<P>Mobile devices such as cell phones and personal digital assistants (PDAs) are becoming increasingly popular tools to access the Internet. Unfortunately, the experience of users attempting to access web pages with these mobile devices has been less than satisfactory because of their small display areas, slow communications links and low computing power. In this paper, we propose a trained scorer to estimate the mobile-friendliness scores of web pages, providing an indication of their suitability for mobile devices. These scores help mobile-friendly pages receive higher ranks in search results when mobile users seek information on the web. Our experiments show that the search results re-ranked by our mobile-friendliness scores increase mobile user satisfaction.</P>
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Song, Li-Jie,Zhang, Wei-Jie,Chang, Zhi-Wei,Pan, Yan-Feng,Zong, Hong,Fan, Qing-Xia,Wang, Liu-Xing Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Invasion and metastasis is the major cause of tumor recurrence, difficulty for cure and low survival rate. Excavating key transcription factors, which can regulate tumor invasion and metastasis, are crucial to the development of therapeutic strategies for cancers. PU.1 is a master hematopoietic transcription factor and a vital regulator in life. Here, we report that, compared to adjacent non-cancerous tissues, expression of PU.1 mRNA in metastatic hepatocellular carcinoma (HCC), but not primary HCC, was significantly down-regulated. In addition, levels of PU.1 mRNA in metastatic hepatoma cell lines MHCC97L and MHCC97H were much lower than in non-metastatic Hep3B cells. Transwell invasion assays after PU.1 siRNA transfection showed that the invasion of hepatoma cell lines was increased markedly by PU.1 knockdown. Oppositely, overexpression of PU.1 suppressed the invasion of these cells. However, knockdown and overexpression of PU.1 did not influence proliferation. Finally, we tried to explore the potential mechanism of PU.1 suppressing hepatoma cell invasion. ChIP-qPCR analysis showed that PU.1 exhibited a high binding capacity with miR-615-5p promoter sequence. Overexpression of PU.1 caused a dramatic increase of pri-, pre- and mature miR-615-5p, as well as a marked decrease of miR-615-5p target gene IGF2. These data indicate that PU.1 inhibits invasion of human HCC through promoting miR-615-5p and suppressing IGF2. These findings improve our understanding of PU.1 regulatory roles and provided a potential target for metastatic HCC diagnosis and therapy.
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Variable Coefficient Inductance Model-Based Four-Quadrant Sensorless Control of SRM
Song-Yan Kuai,Xue-Feng Li,Xing-Hong Li,Jinyang Ma 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.6
The phase inductance of a switch reluctance motor (SRM) is significantly nonlinear. With different saturation conditions, the phase inductance shape is clearly changed. This study focuses on the relationship between coefficient and current in an inductance model with ignored harmonics above the order of 3. A position estimation method based on the variable coefficient inductance model is proposed in this paper. A four-quadrant sensorless control system of the SRM drive is constructed based on the relationship between variable coefficient inductance and rotor position. The proposed algorithms are implemented in an experimental SRM test setup. Experimental results show that the proposed method estimates position accurately in operating two/four-quadrants. The entire system also has good static and dynamic performance.
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