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Prognosis of early mucinous gastric carcinoma
Ryu, Seong Yeob,Kim, Ho Gun,Lee, Jae Hyuk,Kim, Dong Yi The Korean Surgical Society 2014 Annals of Surgical Treatment and Research(ASRT) Vol.87 No.1
<P><B>Purpose</B></P><P>Little is known about the clinicopathological features of early mucinous gastric carcinoma (MGC). The purpose of this study was to compare the clinicopathological features and prognosis between patients with early MGC and those with early nonmucinous gastric carcinoma (NMGC).</P><P><B>Methods</B></P><P>We reviewed the records of 2,732 patients diagnosed with gastric carcinoma who were treated surgically. There were 14 patients (0.5%) with early MGC and 958 with early NMGC.</P><P><B>Results</B></P><P>Early MGC patients had a higher prevalence of elevated type (71.4%) compared with early NMGC patients (29.5%). More early MGC patients had submucosal carcinoma, compared with early NMGC patients (78.6% <I>vs.</I> 64.1%). The overall 5-year survival of the patients with early MGC was 97.2% as compared with 92.7% for the patients with early NMGC (P < 0.01). The statistically significant prognostic parameters influencing the 5-year survival rate according to Cox's proportional hazard regression model were: age (risk ratio, 2.22; 95% confidence interval [CI], 1.62-3.04; P < 0.01); sex (risk ratio, 1.97; 95% CI, 1.42-2.73; P < 0.01); and lymph node metastases (risk ratio, 1.88; 95% CI, 1.28-2.77; P < 0.01).</P><P><B>Conclusion</B></P><P>Patients with early MGC had a better prognosis than those with early NMGC. Mucinous histology itself appears not to be an independent prognostic factor. Therefore, early detection is important for improving the prognosis for patients with gastric carcinoma regardless of tumor histology.</P>
Prognosis of early mucinous gastric carcinoma
Seong Yeob Ryu,Ho Gun Kim,Jae Hyuk Lee,Dong Yi Kim 대한외과학회 2014 Annals of Surgical Treatment and Research(ASRT) Vol.87 No.1
Purpose: Little is known about the clinicopathological features of early mucinous gastric carcinoma (MGC). The purpose of this study was to compare the clinicopathological features and prognosis between patients with early MGC and those with early nonmucinous gastric carcinoma (NMGC). Methods: We reviewed the records of 2,732 patients diagnosed with gastric carcinoma who were treated surgically. There were 14 patients (0.5%) with early MGC and 958 with early NMGC. Results: Early MGC patients had a higher prevalence of elevated type (71.4%) compared with early NMGC patients (29.5%). More early MGC patients had submucosal carcinoma, compared with early NMGC patients (78.6% vs. 64.1%). The overall 5-year survival of the patients with early MGC was 97.2% as compared with 92.7% for the patients with early NMGC (P < 0.01). The statistically significant prognostic parameters influencing the 5-year survival rate according to Cox’s proportional hazard regression model were: age (risk ratio, 2.22; 95% confidence interval [CI], 1.62?3.04; P < 0.01); sex (risk ratio, 1.97; 95% CI, 1.42?2.73; P < 0.01); and lymph node metastases (risk ratio, 1.88; 95% CI, 1.28?2.77; P < 0.01). Conclusion: Patients with early MGC had a better prognosis than those with early NMGC. Mucinous histology itself appears not to be an independent prognostic factor. Therefore, early detection is important for improving the prognosis for patients with gastric carcinoma regardless of tumor histology.
Parametric Study on Design Factors of the Shutdown Cooling Heat Exchanger Using the Taguchi Method
Kim Seong Hoon,Ryu Seung Yeob,Choi Byung Seon,Yoon Juhyeon,Bae Yoon Yeong,Zee Sung Kyun Korean Nuclear Society 2003 Nuclear Engineering and Technology Vol.35 No.3
The Taguchi method was applied to investigate the effect of design factors on the performance of the shutdown cooling heat exchanger in the SMART-P. This method provided the simulation matrix for the KDESCENT program and an efficient tool for analyzing the simulation results. Levels of the design factors were selected by the effectiveness-NTU method. From 18 runs with the KDESCENT program, it was found that the performance of the system was greatly influenced by the inlet temperature at the shell side and the mass flow rate of the reactor coolant at the tube side. After applying the Taguchi method, we identified the important design factor that should be controlled and designed carefully. This method provides an efficient way to estimate the influence of each design factor on a system performance.
Preoperative predictors of malignant gastric submucosal tumor
Ho Goon Kim,Seong Yeob Ryu,Sang Kwon Yun,Jae Kyoon Joo,Jae Hyuk Lee,Dong Yi Kim 대한외과학회 2012 Annals of Surgical Treatment and Research(ASRT) Vol.83 No.2
Purpose: The preoperative prediction of malignant potential in patients with gastric submucosal tumors (SMTs) plays an important role in decisions regarding their surgical management. Methods: We evaluated the predictors of malignant gastric SMTs in 314 patients with gastric SMTs who underwent surgery in Chonnam National University Hospital. Results: The malignant SMTs were significantly associated with age (odds ratio [OR], 1.067; 95% confidence interval [CI], 1.042 to 1.091; P < 0.0001), presence of central ulceration (OR, 2.690; 95% CI, 1.224 to 5.909; P = 0.014), and tumor size (OR, 1.791; 95% CI, 1.483 to 2.164; P < 0.0001). Receiver operating characteristic curve analysis showed that tumor size was a good predictor of malignant potential. The most relevant predictor of malignant gastric SMT was tumor size with cut-offs of 4.05 and 6.40 cm. Conclusion: Our findings indicated that age, central ulceration, and tumor size were significant preoperative predictors of malignant SMTs. We suggest that 4 cm be selected as a threshold value for malignant gastric SMTs. In patients with a gastric SMT larger than 4 cm with ulceration, wide resection of the full thickness of the gastric wall or gastrectomy with adequate margins should be performed because of its malignant potential.