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Cu-Mn-Al 합금에서 Al 이 Mn 원자의 확산에 미치는 영향
김동의 대한금속재료학회(대한금속학회) 1980 대한금속·재료학회지 Vol.18 No.6
Cu-Mn-Al 삼원계합금의 FCC-γ 상영역에서, 기체-고체접촉방법에 의하여 Mn의 상호확산계수 D~_(Mn)을 Mn과 Al의 함수로 구하였다. Mn의 확산 계수는 Mn 함량이 증가하면 증가하고, 불순물로서 Al이 증가하면 오히려 감소하는 경향을 보였다. 즉, Cu-Mn의 2원계 합금에서, 10a/o Mn일 경우 D~_(Mn)은 0.50×10^(-9) ㎠/sec, 20a/o Mn에서는 0.93×10^(-9) ㎠/sec 이였으나, 0.5a/o Al이 첨가되므로서, 10a/o Mn일 경우 D~_(Mn)은 0.43×10^(-9) ㎠/sec, 20a/o Mn에서는 0.82×10^(-9) ㎠/sec로 감소하였다. Interdiffusion coefficients of manganese D~_(Mn) were investigated as the functions of solute atoms of manganese and impurity atoms of aluminum in FCC-γ phase of Cu-Mn-Al ternary alloy at 800℃ by using the vapor-solid couple method. Diffusivity of manganese are gradually increased by the addition of manganese, but decreased by the addition of aluminum. D~_(Mn) in Cu-Mn binary alloy is 0.50×10^(-9) ㎠/sec at 10a/o Mn, 0.93×10 D~_(Mn) ㎠/sec at 20a/o Mn, but it is decreased by the addition of 0.5a/o Al to 0.43×10^(-9) ㎠/sec at 10a/o Mn, 0.82×10^(-9) ㎠/sec at 20a/o Mn.
기능성 위장장애 환자의 소화불량 제증상 치료에 있어서 콤비짐^(�)정의 임상효과
김동의,주재환,추상우,김형륵,조철균,김영진,김현종,김신곤 中央醫學社 1996 中央醫學 Vol.61 No.12
Functional dyspepsia has been considered, until recently, to be a nebulous syndrome, in part because of the lack of a structural explanation for the symptoms and because of the apparent heterogeneity of the patients labeled with this diagnosis. Although many definitions have been offered, there is now reasonable consensus that dyspepsia refers to persistent or recurrent pain or discomfort that is centered on the upper abdomen ; the discomfort may be characterized by postprandial fullness, early satiety, nausea or upper abdominal bloating. The diagnosis of dyspepsia must not be restricted to those with meal-related symptoms because there is no clinical condition, including chronic peptic ulceration, in which the symptoms are exclusively confined to the postprandial period. The majority of the patients with chronic or recurrent dyspepsia do not have a peptic ulcer or any other recognized structural or biochemical abnormality that definitely explains the symptoms ; these patients are classified as having functional dyspepsia. Ideally, therapy for functional dyspepsia should be targeted at correcting an individual's underlying pathophysiologic disturbances. However, the mechanisms that produce symptoms in patients with functional dyspepsia remain poorly understood. A polyvalent digestive product Combizym� has a powerful combination of enzymes with broad activity and broad pH spectrum. It acts from the stomach to the small intestine and has a complete digestive effect on protein, carbohyrate and fat. We treated Combizym� in patients with functional dyspepsia with open, noncomparative study. The results are as follows ; 1. The improvement of the symptoms were 96.4 % in nausea and vomiting, 92.6 % in bloating, other symptoms were also improved over 75 %. 2. There was only mild pruritus in a patient and others were well tolerated during the experiment. 3. Overall improvement rate was 86.7 % of 30 patients. In conclusion, Combizym� is a safe and effective digestive drug in patients with functional dyspepsia.
김동의 대한금속재료학회(대한금속학회) 1985 대한금속·재료학회지 Vol.23 No.2
The diffusion of silicon and carbon atoms was studied in γphase of Fe-Si-C ternary alloy at 1000℃ under the steady-state condition. Diffusion cell assembly, essentially, consisted of a thin sheet of pure iron and a silicon powder (60 mesh) which was packed on one side of the membrane, while the other side was packed with manganese powder. Both sides of the pure iron membrane, were packed with 0.7 mm φcarbon rods to maintain the equal carbon potentials. Atomic rnobilitics of silicon were measured along each of the steady-state diffusion concentration profiles. Diffusion coefficient of silicon D_(22) was found to be, 39∼5.79×10^(-11) ㎠/s in Fe-2.8∼1.5 at. pct Si-2.2∼1.5 at, pct C system, where the diffusivity of silicon was increased by the addition of silicon and carbon atoms. Interstitial carbon atoms diffuse more rapidly than the substitutional silicon atoms. The carbon atoms on the gradient of slow moving component, will easily become a state of a transient equilibrium. The ratios of diffusivity of carbon D_(11) and cross term D_(12) were calculated by D_(12)/D_(11) ∼ 0.1∼0.19 at Yc=0.019∼0.021 in a Fe-Si-C alloy.