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Naeem Saddique,Christian Bernhofer,Rico Kronenberg,Muhammad Usman 한국기상학회 2019 Asia-Pacific Journal of Atmospheric Sciences Vol.55 No.4
In this study, statistical downscaling models were used to project possible future patterns of precipitation and temperature in the Jhelum River basin shared by Pakistan and India. In-situ meteorological data were used to downscale precipitation and temperature using different General Circulation Models (i.e., CanESM2, BCC-CSM1–1, and MICROC5) relative to baseline (1961– 1990) under the Representative Concentration Pathway (RCP) scenarios RCP4.5 and RCP8.5. The downscaling models used were the Statistical Downscaling Model (SDSM), which uses multiple linear regression and weather generator methods, and the Long Ashton Research Station Weather Generator (LARS-WG), which uses weather generators. The results showed that the SDSM performance was slightly better than that of LARS-WG during validation and that the representation of the simulated mean monthly precipitation was more correct than that of monthly precipitation. The results also revealed that BCC-CSM1–1 performed better than CanESM2 and MICROC5 in the study region. The future annual mean temperature and precipitation are expected to rise under both RCP scenarios. The changes in the annual mean temperature and precipitation with LARS-WG were relatively higher than those with SDSM. Out of four seasons, winter and autumn are expected to be more diverse with regard to precipitation changes. However, although both models yielded non-identical results, it is certain that the basin will face a hotter climate in the future.
Ground state opto-electronic and thermoelectric response of cubic XSnO3 (X = Ba, Sr) compounds
M. Bilal Saddique,Muhammad Rashid,Adnan Afzal,Shahid M. Ramay,Farooq Aziz,Asif Mahmood 한국물리학회 2017 Current Applied Physics Vol.17 No.8
The density functional has been implemented to deliberate the cubic perovskite XSnO3 (X ¼ Ba, Sr) for their elastic, electronic, optical as well as thermoelectric characteristic. The XSnO3 (X ¼ Ba, Sr) illustrates good pact of lattice parameter for these iso-structural compounds having cubic perovskite structure. The generalized gradient approximation based on the exchange-correlation functional is applied for computing structural and mechanical characteristic, whereas the electronic, optical and thermoelectric properties have been studied by the functional suggested by Tran and Blaha that is termed as of modified Becke-Johnson (mBJ) functional. The thermodynamics stability is recognized through the expression of enthalpies of formation, which is further verified from the calculated structural properties of cubic perovskite XSnO3 (X ¼ Ba, Sr). Moreover, various elastic parameters such has bulk modules B, Cij, shear modulus G, Young's modulus Y, anisotropy factor, B/G ratio and Poisson's ratio n have also been reported. It has been observed by band structure computation that the studied compounds exhibit an indirect band gap between the unoccupied Ba/Sr 6s/5s and the occupied O 2p orbitals. Detailed study of optical properties is presented under the incident photon energy upto 28 eV. Our computed static dielectric constant ε2(0) and refractive index n(0) are comparable with other theoretical and experimental values. Thermoelectric properties are presented in terms of computed Seebeck coefficient, electrical and thermal conductivities and their variation with the rise in temperature suggest that the studied compounds may find applications in the construction of various thermo-electric devices.
Indigenous Radiosynthesis of [131I]Iodobenzylguanidine ([131I]mIBG) for Neuroblastoma Imaging
Nadeem Ahmed Lodhi,Muhammad Irfan,Muhammad Nasir Saddique,Kahkshan Bashir Mir,Naseer Ahmed,Shazia Fatima,Mumtaz Khan,Muhammad Wasim,Samina Roohi 대한방사성의약품학회 2022 Journal of radiopharmaceuticals and molecular prob Vol.8 No.2
Indigenous diagnostic dose of 131I-labeled meta-iodobenzylguanidine ([131I]mIBG) was prepared via Cu+ catalyzed isotope exchange reaction generated in situ by sodium metabisulfite for imaging of neuroblastoma tumor. [131I]mIBG was produced in overall 85-90% radiochemical yield. The average amount of radioactivity of [131I]mIBG was 2164 MBq (1998-2331MBq) with an average specific activity > 1000 MBq/mg at the end of synthesis. The radiochemical purity was ≥ 99.9% after purification through Dowex-1 × 8 ion exchange resin (100-150 mesh) at the date of preparation. The stability of [131I]mIBG at concentration 480-555 MBq/mL was > 97% at 4 °C after 4 days. The room temperature (25 °C) stability of [131I]mIBG was > 98% after 24 h. Biodistribution of [131I]mIBG in patient showed uptake in salivary glands, liver, spleen and excreted though urinary bladder. Neuroendocrine medicated uptake into tumor lesion and metastatic sites were noted which strongly correlate with the morphological abnormalities of patient.