http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
An Evaluation of Assessing the Functional Movement Screen™ from Video Playback
Matthew D Portas,Daniel Meek,Warren Gregson,Barry Drust 한국코칭능력개발원 2015 International Journal of Coaching Science Vol.9 No.2
The study aimed to evaluate the method comparison and intra-rater test-retest reliability of the Functional Movement Screen when assessed by real-time and video playback. Eighteen participants (Age: 22 ± 2 years, Height: 1.77 m ± 0.10 m, Weight: 78.2 ± 11.5 kg, 15 males and 3 females), participated. Participants were scored during the screen in real-time by an experienced coach. Each screen was also video recorded in the frontal and sagittal plane. The coach then scored each FMS via video, in a randomised order, 3 days (video-1) and 7 days later (video-2). Median and interquartile range were calculated for the group score in each assessment. The weighted kappa statistic, percentage of agreement and bias were then calculated for each FMS test.. The median (interquartile ranges) for the group FMS score was 16.0 (15.0 and 17.0) for the live assessment; 16 (14.0 and 17.0) for video-1 and 16 (13.8 and 17.0) for video-2. The mean (SD) agreement across all tests live compared to video was 87.4% (11.1) with a weighted kappa statistic of 0.9 (0.1) (almost perfect). These results provide guidance for the interchangeably of these techniques in practice and confirm the legitimacy of the approach for the previous work that used video to assess reliability of measurement.
Neurotoxic chemicals in adipose tissue : A role in puzzling findings on obesity and dementia
Lee, Duk-Hee,Porta, Miquel,Lind, Lars,Lind, P. Monica,Jacobs Jr., David R. Ovid Technologies (Wolters Kluwer) - American Acad 2018 Neurology Vol.90 No.4
<P>Midlife obesity is associated with increased risk of dementia, whereas late-life obesity is commonly associated with a lower risk of dementia. Although methodologic issues are often discussed in this apparent risk reversal, chronic exposure to low-dose organochlorine pesticides (OCPs), an emerging risk factor for dementia in general populations, may contribute to a direct explanation for these differences. OCPs are strong lipophilic chemicals with very long half-lives (several years), primarily stored in adipose tissue and very slowly released and metabolized over years. As serum concentrations of neurotoxic OCPs strongly correlate with brain OCPs (<I>r</I> = 0.95), any condition enhancing the release of OCPs from the adipose tissue into circulation would increase the risk of dementia. Increased release of OCPs from adipose tissue typically occurs in (1) dysfunctional adipocytes accompanied by uncontrolled lipolysis and (2) weight loss. Weight gain may help sequester circulating OCPs in adipose tissue. As obesity is the most common reason that adipocytes become dysfunctional, midlife obesity can increase dementia risk through the chronic release of OCPs into circulation. However, late-life obesity potentially decreases dementia risk because weight loss after midlife will increase the release of OCPs while weight gain may actually decrease the release. These countervailing forces may underlie paradoxical associations with dementia of obesity in midlife vs late life which is influenced by weight change after midlife. This hypothesis should be tested in future experimental and human studies on obesity and dementia.</P>
Soft biometrics through hand gestures driven by visual stimuli
Nahumi Nugrahaningsih,Marco Porta 한국통신학회 2019 ICT Express Vol.5 No.2
We present a novel biometric solution which exploits hand gestures, tracked by the Microsoft Kinect sensor, performed in response to a circle randomly appearing in five predefined screen positions. Features of both hand and screen pointer are used for classification purposes, considering both the whole 20-path trajectory and shorter routes. In particular, we search for the “optimal” trajectory length which assures a good trade-off between precision and user effort. For identification, the approach achieves classification accuracies ranging from 0.748 to 0.942. For verification, accuracy is still satisfactory (always higher than 0.962), despite moderate specificity values.
Ida Palazzo,Marialuigia Raimondo,Giovanna Della Porta,Liberata Guadagno,Ernesto Reverchon 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.90 No.-
Supercritical emulsions extraction (SEE-C) technology was used to produce PMMA/diglycidyl ether ofbisphenol A microcapsules acting as a health-monitoring element. A comparison between SEE-C andsolvent evaporation was carried out. Best results were obtained using SEE-C: spherical microcapsuleswith a smooth surface and a mean size of 220 nm, with an encapsulation efficiency up to 79%, wereobtained. SEE-C capsules preserve their stability for the entire time frame analyzed (30 days). Impact tests were carried out on strips of carbonfiber reinforced composites coated with an aqueouspaint in which capsules were previously dispersed: dye leaking associated with capsules breaking wasevidenced.
Effect of Annurca Apple Polyphenols on Human HaCaT Keratinocytes Proliferation
Stefania D’Angelo,Raffaele La Porta,Maria Napolitano,Patrizia Galletti,Lucio Quagliuolo,Mariarosaria Boccellino 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.11
Polyphenols have been demonstrated to have clear antioxidant activities in vitro. However, in complex biological systems, they exhibit additional properties, which are yet poorly understood. The apple is among the most consumed fruits worldwide, and several studies suggest that apple polyphenols could play a role in the prevention of degenerative diseases. The present study aimed at evaluating the Annurca apple polyphenol extract (APE) effects both proliferation and apoptosis on HaCaT cells. The data indicate that apple polyphenolic compounds had significant antiproliferative action on HaCaT cells. The fluorescence-activated cell-sorting analysis showed that APE induced cell apoptosis in a dose-dependent manner. Moreover, apple polyphenols induced apoptosis in epithelial cells by triggering a death receptor-associated extrinsic pathway p53-independent. APE was also capable of inducing morphological changes as evidenced by nuclear condensation. The cellular, morphological, and molecular data unequivocally demonstrated that induction of cellular apoptosis was mainly responsible for the previously observed antiproliferation-induced APE on HaCaT keratinocytes. Our experimental results suggest that apple polyphenols are a promising source from which a natural-based topical agent could be developed for skin diseases treatment.
La Inserción Argentina en las Cadenas Globales de Valor
Daniel Schteingart,Juan Santarcangelo,Fernando Porta 한국라틴아메리카학회 2017 라틴아메리카연구 Vol.30 No.3
The aim of this paper is to analyze how Argentina is currently involved in Global Value Chains. First we make a comparison between the country’s current position (strictly speaking, the year 2011) in GVC and the situation registered in the mid-1990s. Second, we analyze which sectors and countries/regions contribute most to Argentina’s participation in the GVC. Finally, we study the implications of the current degree of participation for economic development. The novelty of this study is based on the use of data relatively unexplored: Trade in Value Added OECD; it allows us to make a general analysis of all the chains in which Argentina participates.
Comprehensive Characterization of Cancer Driver Genes and Mutations
Bailey, Matthew H.,Tokheim, Collin,Porta-Pardo, Eduard,Sengupta, Sohini,Bertrand, Denis,Weerasinghe, Amila,Colaprico, Antonio,Wendl, Michael C.,Kim, Jaegil,Reardon, Brendan,Kwok-Shing Ng, Patrick,Jeon Elsevier 2018 Cell Vol.174 No.4
OH, WILLIAM K.,McDERMOTT, DAVID,PORTA, CAMILLO,LEVY, ANTONIN,ELAIDI, REZA,SCOTTE, FLORIAN,HAWKINS, ROBERT,CASTELLANO, DANIEL,BELLMUNT, JOAQUIM,RHA, SUN YOUNG,SUN, JONG-MU,NATHAN, PAUL,FEINBERG, BRUCE D.A. Spandidos 2014 International journal of oncology Vol.44 No.1
<P>The aim of this study was to assess the treatment patterns and safety of sunitinib, sorafenib and bevacizumab in real-world clinical settings in US, Europe and Asia. Medical records were abstracted at 18 community oncology clinics in the US and at 21 tertiary oncology centers in US, Europe and Asia for 883 patients ≥18 years who had histologically/cytologically confirmed diagnosis of advanced RCC and received sunitinib (n=631), sorafenib (n=207) or bevacizumab (n=45) as first-line treatment. No prior treatment was permitted. Data were collected on all adverse events (AEs) and treatment modifications, including discontinuation, interruption and dose reduction. Treatment duration was estimated using Kaplan-Meier analysis. Demographics were similar across treatment groups and regions. Median treatment duration ranged from 6.1 to 10.7 months, 5.1 to 8.5 months and 7.5 to 9.8 months for sunitinib, sorafenib and bevacizumab patients, respectively. Grade 3/4 AEs were experienced by 26.0, 28.0 and 15.6% of sunitinib, sorafenib and bevacizumab patients, respectively. Treatment discontinuations occurred in 62.4 (Asia) to 63.1% (US) sunitinib, 68.8 (Asia) to 90.0% (Europe) sorafenib, and 66.7 (Asia) to 81.8% (US) bevacizumab patients. Globally, treatment modifications due to AEs occurred in 55.1, 54.2 and 50.0% sunitinib, sorafenib and bevacizumab patients, respectively. This study in a large, global cohort of advanced RCC patients found that angiogenesis inhibitors are associated with high rates of AEs and treatment modifications. Findings suggest an unmet need for more tolerable agents for RCC treatment.</P>