Synthesis of Co(II), Ni(II) and Cu(II) Complexes from Schiff base Ligand and Reactivity Studies with Thermosetting Epoxy Resin

B. Lakshmi,Krishna Reddy K. Rama,Gouda Avaji Prakash,K. N. Shivananda,K. N. Mahendra 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.5

A hybrid thermosetting maleimido epoxy compound 4-(N-maleimidophenyl) glycidylether (N-MPGE) containing Co(II), Ni(II) and Cu(II) ions was prepared by curing N-MPGE and tetradentate Schiff base Co(II),Ni(II) and Cu(II) complexes. The curing polymerization reaction of N-MPGE with metal complexes as curing agents was studied. The cured samples were studied for thermal stability, chemical (acid/alkali/solvent) and water absorption resistance and homogeneity of the cured systems. The tetradentate Schiff base, 3-[(Z)-2-piperazin-1-yl-ethylimino]-1,3-dihydro indol-2-one was synthesized by the condensation of Isatin (Indole-2, 3-dione) with 1-(2-aminoethyl)piperazine (AEP). Its complexes with Co(II), Ni(II) and Cu(II) have been synthesized and characterized by microanalysis, conductivity, Uv-Visible, FT-IR, TGA and magnetic susceptibility measurements. The spectral data revealed that the ligand acts as a neutral tetradentate Schiff base and coordinating through the azomethine nitrogen, two piperazine nitrogen atoms and carbonyl oxygen

Synthesis of Co(II), Ni(II) and Cu(II) Complexes from Schiff base Ligand and Reactivity Studies with Thermosetting Epoxy Resin

Lakshmi, B.,Shivananda, K.N.,Prakash, Gouda Avaji,Rama, Krishna Reddy K.,Mahendra, K.N. Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.5

A hybrid thermosetting maleimido epoxy compound 4-(N-maleimidophenyl) glycidylether (N-MPGE) containing Co(II), Ni(II) and Cu(II) ions was prepared by curing N-MPGE and tetradentate Schiff base Co(II), Ni(II) and Cu(II) complexes. The curing polymerization reaction of N-MPGE with metal complexes as curing agents was studied. The cured samples were studied for thermal stability, chemical (acid/alkali/solvent) and water absorption resistance and homogeneity of the cured systems. The tetradentate Schiff base, 3-[(Z)-2-piperazin-1-yl-ethylimino]-1,3-dihydro indol-2-one was synthesized by the condensation of Isatin (Indole-2, 3-dione) with 1-(2-aminoethyl)piperazine (AEP). Its complexes with Co(II), Ni(II) and Cu(II) have been synthesized and characterized by microanalysis, conductivity, Uv-Visible, FT-IR, TGA and magnetic susceptibility measurements. The spectral data revealed that the ligand acts as a neutral tetradentate Schiff base and coordinating through the azomethine nitrogen, two piperazine nitrogen atoms and carbonyl oxygen.

Mathematical Modeling on AC Pollution Flashover Performance of Glass and Composite Insulator

N.B.Prakash,M.Parvathavarthini,R.Madavan 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.4

While considering the current scenario, in this world power demand goes on increases day by day. Frequent power outages occur in high voltage transmission line due to the deprived performance of polluted insulators; this affects overall operation of power system and may indirectly impinge on the growth of production sector. Many researchers are keenly taking efforts to provide highly reliable and stable power to neediest. In this paper, A.C pollution flashover performance of disc type glass insulator and composite long rod insulators investigation under various artificial pollutions by varying Equivalent Salt Density Deposition (ESDD) levels. Here, we use different types of pollution methods like binding method, dipping method and spraying methods with different types of pollutants concentration. Based on dimensional analysis, four different Mathematical models have been developed to predict the A.C pollution Flashover Voltage (FOV) of insulators. Both the experimental and mathematically modeled results are compared; it’s observed that mathematical model 3 yields better results.

Mathematical Modeling on AC Pollution Flashover Performance of Glass and Composite Insulator

Prakash, N.B.,Parvathavarthini, M.,Madavan, R. The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.4

While considering the current scenario, in this world power demand goes on increases day by day. Frequent power outages occur in high voltage transmission line due to the deprived performance of polluted insulators; this affects overall operation of power system and may indirectly impinge on the growth of production sector. Many researchers are keenly taking efforts to provide highly reliable and stable power to neediest. In this paper, A.C pollution flashover performance of disc type glass insulator and composite long rod insulators investigation under various artificial pollutions by varying Equivalent Salt Density Deposition (ESDD) levels. Here, we use different types of pollution methods like binding method, dipping method and spraying methods with different types of pollutants concentration. Based on dimensional analysis, four different Mathematical models have been developed to predict the A.C pollution Flashover Voltage (FOV) of insulators. Both the experimental and mathematically modeled results are compared; it's observed that mathematical model 3 yields better results.

Cytogenetic endpoints and Xenobiotic gene polymorphism in lymphocytes of hospital workers chronically exposed to ionizing radiation in Cardiology, Radiology and Orthopedic Laboratories

Vellingiri, B.,Shanmugam, S.,Subramaniam, M.D.,Balasubramanian, B.,Meyyazhagan, A.,Alagamuthu, K.,Prakash, V.,Shafiahammedkhan, M.,Kathannan, S.,Pappuswamy, M.,Raviganesh, B.,Anand, S.,Shahnaz N, D.,C Academic Press 2014 Ecotoxicology and environmental safety Vol.100 No.-

Ionizing radiation (IR) is known as a classical mutagen capable of inducing various kinds of stable and unstable chromosomal aberrations (CA) including the possibility of increasing the incidence of DNA damage. This study aims to assess occupationally induced CA in workers chronically exposed to low doses of IR in Radiology (RL), Cardiology (CL) and Orthopedic (OL) Laboratories in hospitals of Tamil Nadu. We performed the analysis of CA by trypsin G-banding, micronucleus (MN) assay, Comet assay and Xenobiotic-metabolizing gene polymorphisms (GSTM1, GSTT1 and GSTP1) in 56 exposed and 56 control subjects who were matched for gender and age (+/-2 years). Higher degree of CA and MN frequencies were observed in exposed groups, especially in CL subjects compared to other exposed groups and controls (p<0.05). Higher frequency of DNA tail length and tail moment was observed in the CL exposed subjects compared to the RL and OL subjects. The frequencies of GSTM1 and GSTT1 null genotypes were 39.3 percent and 14.3 percent, respectively. No significant difference in allele frequencies between exposed subjects and controls were observed (p=0.0128). Using multiple linear regression analysis, statistical significance was determined for work duration and age for the CL, RL and OL workers and the examination of the possible impact by confounding factors showed few significant influences on the radiation exposure, as a specific biomarker. However, the findings from the present study suggest that, awareness should be created among the personnel exposed to radiations in hospital laboratories, highlighting the necessity of applying radiation protection principles against medical radiation exposure.

Interrelationships Between Follicular Size, Estradiol-17β, Progesterone and Testosterone Concentrations in Individual Buffalo Overian Follicles

Palta, P.,Bansal, N.,Manik, R.S.,Prakash, B.S.,Madan, M.L. Asian Australasian Association of Animal Productio 1998 Animal Bioscience Vol.11 No.3

This study was undertaken to measure the concentrations of estradiol-$17{\beta}$, progesterone and testosterone, and to study their relationship with each other and with follicular size in individual buffalo ovarian follicles categorized as small (4 to 5 mm diameter), medium (6 to 9 mm diameter) and large (${\geq}10mm$ diameter). Steroid hormone concentrations varied markedly within follicles of each size category. Estradiol-$17{\beta}$ concentrations (pmol/ml) were positively related to follicular diameter (R = 0.34, n = 308, p < 0.001) and were significantly higher (p < 0.001) in large (1$118.46{\pm}30.25$), compared to those in medium follicles ($50.32{\pm}8.29$) which, in turn were significantly higher (p < 0.001) than those in small follicles ($19.70{\pm}$5.57). Progesterone and testosterone concentrations (pmol/ml) were not related to follicular diameter and were not different among small ($330.99{\pm}27.32$ and $17.68{\pm}2.44$ respectively), medium ($384.84{\pm}26.20$ and $36.47{\pm}4.55$, respectively) and large follicles ($253.25{\pm}32.23$ and $22.57{\pm}4.48$, respectively). Estradiol-$17{\beta}$ and progesterone concentrations were positively related (R = 0.39, n = 47, p < 0.01) in small, unrelated in medium and negatively related in large follicles (R = -0.59, n = 23, p < 0.01). There was no relationship between estradiol-$17{\beta}$ and testosterone concentrations in follicles of all the three size categories. Progesterone and testosterone concentrations were positively related in large follicles (R = 0.57, n = 18, p < 0.02). There was no relationship between the two hormones in small and medium sized follicles. When the follicles with estradiol-$17{\beta}$/progesterone molar ratios of > 1.00 were considered non-atretic, and the rest at different stages of atresia, 197/208(95%) follicles were found to be atretic.

An Efficient Approach for Inter-Process Synchronization Problem

B. Srinuvasu Kumar,K. Kondaiah,L. Rohit,K. V. Sowmya,N. Sri Prakash 보안공학연구지원센터 2014 International Journal of Software Engineering and Vol.8 No.12

For efficient utilization of CPU and speed up the process done by CPU inter-process synchronization became most important feature in operating system. But no operating system will directly provide support for Inter-Process Synchronization. Inter-Process Synchronization means two or more processes accessing a shared resource and performing some operation at the same time, it also provides concurrent computing among processes. In such instance, data inconsistency may occur because of updating the same shared data item by two processes at the same time. This is the standard problem which occur in any operating system. To avoid such problems some of the synchronization primitives need to be followed. Many solutions have been provided to solve the standard problem such as Blocking Mechanisms, Non-Blocking Mechanisms etc. But those mechanisms are not able to provide an optimal solution. Our idea is to develop an agent which will run in background and automatically detects Inter Process Synchronization problem and solve it without any human intervention. In this paper we are going to provide an agent based solution and develop algorithms for that which ensures smoothly execution of multiple processes without any synchronization problems and increase the performance of the CPU.

Synthesis and Characterization of Schiff Base Metal Complexes and Reactivity Studies with Malemide Epoxy Resin

B. Lakshmi,K. N. Shivananda,Gouda Avaji Prakash,Arun M Isloor,K. N. Mahendra 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.2

A novel malemide epoxy containing Co(II), Ni(II) and Cu(II) ions have been synthesized by curing malemide epoxy resin (MIEB-13) and Co(II), Ni(II) and Cu(II) complexes of macrocyclic bis-hydrazone Schiff base. The Schiff base was synthesized by reacting 1,4-dicarbnyl phenyl dihydrazide with 2,6-diformyl-4-methyl phenol. The Schiff base and its Co(II), Ni(II) and Cu(II) complexes have been characterized by elemental analyses,spectral (IR, 1H NMR, UV-vis., FAB mass, ESR), thermal and magnetic data. The curing reaction of maleimide epoxy compound with metal complexes was studied as curing agents. The stability of cured samples was studied by thermo-gravimetric analyses and which have excellent chemical (acid/alkali/solvent) and water absorption resistance. Further, the scanning electron microscopy (SEM) and definitional scanning colorimetric (DSC) techniques were confirmed the phase homogeneity of the cured systems.

Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits

B. H. Pavithra,K. Jayakumar,N. Prakash 대한수의학회 2009 JOURNAL OF VETERINARY SCIENCE Vol.10 No.4

Investigation was carried out in adult New Zealand white rabbits to study the influence of curcumin pre-treatment on pharmacokinetic disposition of norfloxacin following single oral administration. Sixteen rabbits were divided into two groups of eight each consisting of either sex. Animals in group-I were administered norfloxacin (100 mg/kg body weight p.o), while animals in group-II received similar dose of norfloxacin after pre-treatment with curcumin (60 mg/kg body weight per day, 3 days, p.o). Blood samples were drawn from the marginal ear vein into heparin-coated vials at 0 (zero time), 5, 10, 15, 30 min and 1, 2, 4, 6, 12 and 24 h post-treatment. Plasma norfloxacin concentrations were determined by high performance liquid chromatography. The plasma concentration-time profile of norfloxacin was adequately described by a one-compartment open model. The pharmacokinetic data revealed that curcumin-treated animals had significantly (p ≤ 0.05) higher area under the plasma concentrationtime curve and area under the first moment of plasma drug concentration-time curve. Prior treatment of curcumin significantly (p ≤ 0.05) increased elimination half-life and volume of distribution of norfloxacin. Further treatment with curcumin reduced loading and maintenance doses by 26% and 24% respectively.

Synthesis and Characterization of Schiff Base Metal Complexes and Reactivity Studies with Malemide Epoxy Resin

Lakshmi, B.,Shivananda, K.N.,Prakash, Gouda Avaji,Isloor, Arun M.,Mahendra, K.N. Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.2

A novel malemide epoxy containing Co(II), Ni(II) and Cu(II) ions have been synthesized by curing malemide epoxy resin (MIEB-13) and Co(II), Ni(II) and Cu(II) complexes of macrocyclic bis-hydrazone Schiff base. The Schiff base was synthesized by reacting 1,4-dicarbnyl phenyl dihydrazide with 2,6-diformyl-4-methyl phenol. The Schiff base and its Co(II), Ni(II) and Cu(II) complexes have been characterized by elemental analyses, spectral (IR, $^1H$ NMR, UV-vis., FAB mass, ESR), thermal and magnetic data. The curing reaction of maleimide epoxy compound with metal complexes was studied as curing agents. The stability of cured samples was studied by thermo-gravimetric analyses and which have excellent chemical (acid/alkali/solvent) and water absorption resistance. Further, the scanning electron microscopy (SEM) and definitional scanning colorimetric (DSC) techniques were confirmed the phase homogeneity of the cured systems.