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Ortho-Chlorobenzylidene Malononitrile(CS) 이 흰쥐 피부조직에 미치는 조직학적 영향에 관한 연구
이우용,최봉근,김잉곤,엄기일,정호삼,정호삼,류재만 한양대학교 의과대학 1998 한양의대 학술지 Vol.18 No.1
This study was undertaken to describe the fine structural changes of cytoplasmic organelles in epidermal cells, and the changes of volume and localization of collagen type Ⅰ in the dermis of rat skin by CS(Ortho-chlorobenzylidene malononitrile) application. The experimental animals, 100∼150gm of body weight rats(Sprague-Dawley strain), were sacrificed at 12 hours, 24 hours, 3 day and 5 day after CS application on the hair-shaved back skin. The specimens were prepared for ultrastructural findings, ultrathin sections were stained with uranyl acetate and lead citrate double stain and observed with Hitachi-600 electron microscrope. The others were incubated with rabbit anti rat type Ⅰ collagen antibody as primary antibody, and Goat anti rabbit IgG antibodies as secondary antibody And advidin-biotin-conjugated(ABC) peroxidase procedure was used. All of specimens for immune reactions were observed with light microscope. The results obtained were as follows. 1 Keratinocytes appeared fully necrotized after 3 days of CS application. The epidermis showed degeneration of basal lamina, enlargement of intercellular spaces and necrotic keratinocytes with vacuole and vesicles. And large keratohyalin granules were seen in the shrunken epidermal cells. 2 At 3 or 5 day after CS treatment, the normal cytoplasmic organelles of keratinocytes began to appear on the basal and prickel cells. 3 At 12 hour an 24 hour after CS treatment. The immune reaction of type Ⅰ collagen showed weak reaction in reticular layer of dermis. But at 3 day and 5 day after CS treatment, moderate immune reaction were seen in throughout the dermis. These results suggest that CS application to rak skin may induce changes of keratinocytes and reductive changes of type Ⅰ collagen in the dermis.
Pascal 프로그램을 위한 Syntax Tree의 설계및 구현
심재찬,이만호 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.1
Program transformation in source level is a base for parallel programming environment which helps programmer make good parallel programs. Abstract syntax tree is very good intermediate representation of source program to keep the syntax structure of source program. We design and implement the abstract syntax tree for Pascal program, and show the designed abstract syntax tree is good to use as an intermediate representation of Pascal source program by generating Pascal program with same syntax as source program from abstract syntax tree.
박세진,김희규,김봉준,이천우,옥철호,정만홍 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2
우리나라에서 인기 있는 게장등의 섭취로2) 성인뿐만 아니라 소아에서도 지속적으로 보고되고 있는 폐흡충증은 다양한 임상양상을 보일 수 있다. 저자들은 방사선 소견상 만성 호산구성 폐렴과 유사하였고, 반복적인 치료로 호전된 폐흡충증 1예를 경험하였기에 보고하는 바이다. Paragonimiasis mostly occurs by ingestion of raw or undercooked freshwater crabs or crayfish. Recently, re-emergence of paragonimiasis is reported because of ingestion of raw food such as freshwater fish and Gejang (marinated raw crabs). As the radiological features as well as the laboratory findings are similar to those of chronic eosinophilic pneumonia, the diagnosis of pulmonary paragonimiasis is often difficult and delayed. A 43 year-old female was visited our hospital for migrating and new developing consolidative lung lesions and peripheral blood eosinophilia. The eosinophil profile of leukocyte was 32% (absolute count 2,690 /mm3). Histologic finding was organizing pneumonia pattern with severe infiltration of eosinophils. Parasite specific antibody IgG forParagonimus westermani was positive (titer:0.61, normal range<0.20). After treatment with praziquantel (75mg/Kg once a day for 2days), the chest x-ray was clearly resolved. Follow-up study showed right pleural effusion, newly developed focal infiltration, and several nodules. After retreatment, we couldn't find any recurrent evidence.
A Study on a Page Replacement Algorithm by Page Transition Matrix
Lee, Mann-Ho,Park, Suk-Yoon 충남대학교 자연과학연구소 1983 忠南科學硏究誌 Vol.10 No.2
가상기억장치를 사용하는 운영체제에서는 프로그램이 수행될 때 페이지의 치환이 필요하게 된다. 본 논문에서는 페이지 치환이 필요할 때 치환되어질 페이지를 선정하기 위해서 페이지 전이행렬을 이용하였다. 여기서 사용되어지는 페이지 전이행렬은 한 페이지가 사용된 후 다른 페이지가 사용되어질 확율을 나타내고 있어서, 가까운 장래의 working set을 예측하는데 이용될 수 있다.
Design and Implementation of Mix Simulator for a MIni Computer
Lee, Mann-Ho,Lee, Young-Dae 충남대학교 자연과학연구소 1983 忠南科學硏究誌 Vol.10 No.2
Mix Simulator는 MIX 어셈블리어로 작성한 프로그램을 PERKIN-ELMER 미니컴퓨터를 이용하여 assembling 및 execution 할 수 있도록 개발되었다. 본 논문에서는 MIX Simulator 중 Assembler에서 Lexical Scanning 및 Syntax check routine의 Transition diagram과 Matrix를 다루었고, Execution routine에서는 자주 인용되는 FORTRAN의 Language extension operation들과 어셈블리어 프로그램의 FORTRAN 프로그램과의 링크에 관해 설명하였다.
A Study on Memory Management Policy
Lee, Mann Ho 충남대학교 자연과학연구소 1980 學術硏究誌 Vol.7 No.2
In virtual memory system, the memory management policies affect the total performance of the system with very large variety. Especially the page replacement algorithm is a critical factor in performance evaluation. Am LRU stack algorithm is considered as page replacement. And devise the hardware structure for implementing the stack algorithm by using associative memory.
Sharing Resources by Using Semaphores
Lee, Mann Ho 충남대학교 자연과학연구소 1982 忠南科學硏究誌 Vol.9 No.1
Denning Dennis 는 busy bit, count, head, tail을 내용으로 가지고 있는 semaphore word를 사용하여, semaphore와 그에 관계된 queue에 행해지는 연산 부담을 최소화 하기위한 방법을 제시하였다. 그리고 Weatherly에 Leathrum은 read/modify/write 기억장치를 사용하여, semaphore에 행해지는 연산중 배타적으로 수행되어야만 하는 중요한 부분을 수행하는데 소요되는 시간을 줄이기 위한 방법을 제시하고 있다. 그러나 후자가 제시한 방법은 계수성 semaphore의 성질을 가지고 있지 않기 때문에, 이제까지 사용해 오던 중요한 개념을 상실하고 있다. 본 연구에서는 계수성 semaphore를 이용 가능하도록 이러한 결점을 보완하였다.