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- 저자 : Ma Yupeng (검색결과 5 건)
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Ma Chao,Zhu Haoyu,Liang Shikai,Chang Yuzhou,Mo Dapeng,Jiang Chuhan,Zhang Yupeng 대한영상의학회 2024 Korean Journal of Radiology Vol.25 No.1
Objective: Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology associated with venous sinus stenosis. This study aimed to develop a magnetic resonance venography (MRV)-based radiomics model for predicting a high trans-stenotic pressure gradient (TPG) in IIH patients diagnosed with venous sinus stenosis. Materials and Methods: This retrospective study included 105 IIH patients (median age [interquartile range], 35 years [27– 42 years]; female:male, 82:23) who underwent MRV and catheter venography complemented by venous manometry. Contrast enhanced-MRV was conducted under 1.5 Tesla system, and the images were reconstructed using a standard algorithm. Shape features were derived from MRV images via the PyRadiomics package and selected by utilizing the least absolute shrinkage and selection operator (LASSO) method. A radiomics score for predicting high TPG (≥ 8 mmHg) in IIH patients was formulated using multivariable logistic regression; its discrimination performance was assessed using the area under the receiver operating characteristic curve (AUROC). A nomogram was constructed by incorporating the radiomics scores and clinical features. Results: Data from 105 patients were randomly divided into two distinct datasets for model training (n = 73; 50 and 23 with and without high TPG, respectively) and testing (n = 32; 22 and 10 with and without high TPG, respectively). Three informative shape features were identified in the training datasets: least axis length, sphericity, and maximum three-dimensional diameter. The radiomics score for predicting high TPG in IIH patients demonstrated an AUROC of 0.906 (95% confidence interval, 0.836– 0.976) in the training dataset and 0.877 (95% confidence interval, 0.755–0.999) in the test dataset. The nomogram showed good calibration. Conclusion: Our study presents the feasibility of a novel model for predicting high TPG in IIH patients using radiomics analysis of noninvasive MRV-based shape features. This information may aid clinicians in identifying patients who may benefit from stenting.
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Coactosin-like protein 1 inhibits neuronal migration during mouse corticogenesis
Guohong Li,Yupeng Yin,Jiong Chen,Yanle Fan,Juhong Ma,Yingxue Huang,Chen Chen,Pengxiu Dai,Shulin Chen,Shanting Zhao 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.1
Coactosin-like protein 1 (Cotl1), a member of the actin-depolymerizing factor (ADF)/cofilin family, was first purified from a soluble fraction of Dictyostelium discoideum cells. Neuronal migration requires cytoskeletal remodeling and actin regulation. Although Cotl1 strongly binds to F-actin, the role of Cotl1 in neuronal migration remains undescribed. In this study, we revealed that Cotl1 overexpression impaired migration of both early- and late-born neurons during mouse corticogenesis. Moreover, Cotl1 overexpression delayed, rather than blocked, neuronal migration in late-born neurons. Cotl1 expression disturbed the morphology of migrating neurons, lengthening the leading processes. This study is the first to investigate the function of Cotl1, and the results indicate that Cotl1 is involved in the regulation of neuronal migration and morphogenesis.
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Reliability analysis based on the principle of maximum entropy and Dempster–Shafer evidence theory
Qiu Jiwei,Zhang Jianguo,Ma Yupeng 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.2
The Probability density functions (PDFs) of some uncertain parameters are difficult to determine precisely due to insufficient information. Only the varying intervals of such parameters can be obtained. A method of reliability analysis based on the principle of maximum entropy and evidence theory was proposed to address the reliability problems of random and interval parameters. First, the PDFs and cumulative distribution functions of interval parameters were obtained on the basis of the principle of maximum entropy and Dempster– Shafer evidence theory. Second, the normalized means and standard deviations of interval parameters were obtained using the equivalent normalization method. Third, two explicit iteration algorithms of reliability analysis were proposed on the basis of the advanced firstorder and second-moment method to avoid solving the limit state function and obtain the reliability index. Finally, the accuracy and efficiency of the proposed methods were verified through a numerical example and an engineering case.
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Investigation of temperature sensitivity of actuation performance for piezoelectric fiber composites
Lin, Xiujuan,Chen, Haiyan,Ma, Yupeng,Fisher, John G.,Huang, Shifeng,Zhang, Dou,Cheng, Xin Elsevier 2017 CERAMICS INTERNATIONAL Vol.43 No.13
<P><B>Abstract</B></P> <P>Piezoelectric fiber composites (PFCs) suffer an extremely wide range of temperatures when used in various aerospace structures where temperature effects on the mechanical properties of PFCs are important. In this paper, the actuation performances of PFCs were studied when they were exposed to environmental temperatures from −15°C to 80°C. The results showed that the actuation performance of PFCs was greatly dependent on the environmental temperature. The free strain values and the calculated piezoelectric coefficients d<SUB>33</SUB> and d<SUB>31</SUB> were initially enhanced with the increase of temperature due to the restricted movement of epoxy molecule in the glassy state. The glass transition temperature range of the composite was broadened due to a large number of small pores on the surface of the Pb(Zr,Ti)O<SUB>3</SUB> (PZT) fibers, when the epoxy molecules inside the pores had different transition behaviors compared with those outside the pores. The actuation performance including free strain performance and actuation capability, as well as the piezoelectric coefficients d<SUB>33</SUB> and d<SUB>31</SUB> decreased as the temperature increased above room temperature, since the deformation of epoxy molecules in the viscoelastic state was irreversible.</P>
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Haiyan Wang,Chen Yu,Wanghui Xu,Yupeng Zhang,Yanyi Ma,Yan Lin 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12
An experimental study is performed on the microstructure transformation induced by rapid laser welding in the differentregions of Zr61.4Cu27.8Al4Ni6Y0.8bulk metallic glass (BMG). The laser input energy has a remarkable influence on themicrostructure and microhardness of the Zr-based BMGs. The microstructures in different regions of as-welded joints arediverse. Crystallization happens in heat-affected zone (HAZ) with crystalline dendritic phase of CuZr, which results in thedeterioration of the microhardness to 434.9 ± 17.1 HV in HAZ, much lower than that of parent material as 517 ± 5.0 HV. Meanwhile, the element profiles indicate that intragranular segregation of Cu element occurs during the crystallization process. In the center of molten zone (MZ), the structure is fully amorphous and its hardness is close to that of parent material. In the region transiting from MZ to HAZ, some nano-grains with an average size of 20–50 nm are identified. In addition,several flower-like nanostructured grains of Y2O3phase with a size ranging from 50 to 80 nm are formed in MZ’s matrix. The nanocrystallization is believed to be responsible for the enhancement of the Vickers hardness up to 560.1 ± 8.4 HV inthis region.
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