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Energy Efficiency Assessment in Plunge-Face Grinding of Cemented Tungsten Carbide Cutting Inserts
Luan Carreira,Amauri Hassui,Carlos Ventura 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.6
Due to the high demand for electricity in the manufacturing industry and the efforts to reduce environmental impact, investigations to increase energy efficiency in machining processes have been increasingly carried out. However, information on the behavior of insert grinding process is rarely found. Within this context, this work presents results related to the influence of grinding parameters and abrasive tool characteristics on the energy efficiency during plunge-face grinding of cemented tungsten carbide cutting inserts. For this, grinding forces and consumed electrical energy were measured during the process and sustainability indexes to analyze the relation between insert quality (surface and edge roughness) and consumed energy were calculated in different process conditions. As a result, it was observed that grinding parameters had little influence on insert quality, but an increase in the axial feed speed reduced the consumed energy in approximately 60%, leading to sustainability indexes next to one, i.e., to a greater equilibrium between energy consumption and quality properties.
Luan, Yun-Yan,Liu, Zi-Min,Zhong, Jin-Yi,Yao, Ru-Yong,Yu, Hong-Sheng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Vasculogenic mimicry (VM) refers to the unique ability of highly aggressive tumor cells to mimic the pattern of embryonic vasculogenesis, which was associated with invasion and metastasis. The grape seed proanthocyanidins (GSPs) had attracted much attention as a potential bioactive anti-carcinogenic agent. However, GSPs regulation of VM and its possible mechanisms in a triple-negative breast cancer cells (TNBCs) remain not clear. Therefore, we examined the effect of GSPs on VM information in HCC1937 cell model. In this study, we identified the VM structure via the three-dimensional (3D) matrix in vitro. Cell viability was measured using the CCK8 assay. The effects of GSPs on human triple-negative breast cancer cells (TNBCs) HCC1937 in terms of related proteins of VM information were determined using western blot analysis. In vitro, the tubular networks were found in highly invasive HCC1937 cells but not in the non-invasive MCF-7 cells when plated on matrigel. The number of vascular channels was significantly reduced when cells were exposed in GSPs ($100{\mu}g$/ml) and GSPs ($200{\mu}g/mL$) groups (all p<0.001). Furthermore, we found that treatment with GSPs promoted transition of the mesenchymal state to the epithelial state in HCC1937 cells as well as reducing the expression of Twist1 protein, a master EMT regulator.GSPs has the ability to inhibit VM information by the suppression of Twist1 protein that could be related to the reversal of epithelial-to-mesenchymal (EMT) process. It is firstly concluded that GSPs may be an p otential anti-VM botanical agent for human TNBCs.
Luan, Qinmeng,Britton, T. Benjamin,Jun, Tea-Sung Elsevier 2018 Materials science & engineering. properties, micro Vol.734 No.-
<P><B>Abstract</B></P> <P>Titanium alloys are widely used in light weight applications such as jet engine fans, where their mechanical performance under a range of loading regimes is important. Titanium alloys are mechanically anisotropic with respect to crystallographic orientation, and remarkably titanium creeps at room temperature. This means that the strain rate sensitivity (SRS) and stress relaxation performance are critical in predicting component life. In this work, we focus on systematically exploring the macroscopic SRS of Grade 1 commercially pure titanium (CP Ti) with varying grain sizes and texture using uniaxial compression. Briefly, we find that Ti samples had positive SRS and samples compressed along the sheet rolling direction (RD) (i.e. soft grains dominant) were less rate sensitive than bars compressed along the sheet normal direction (ND) (i.e. hard grains dominant). We attribute this rate sensitivity to the relative activity of slip and twinning. Within the grain size range of ~ 317 ± 7 μ m , we observe an increase in the rate sensitivity, where volume fraction of { 10 1 ̅ 2 } < 10 1 ̅ 1 > T1 tensile twins was low, and the twin width at different strain rates were similar. These observations imply that the macroscopic rate sensitivity is controlled by the ensemble behaviour of local deformation processes: the amount of slips accumulated at grain boundaries affects the SRS, which is grain size and texture dependent. We hope that this experimental study motivates mechanistic modelling studies using crystal plasticity, including strain rate sensitivity and twinning, to predict the performance of titanium alloys.</P>
Gene Expression Profiling in the Pituitary Gland of Laying Period and Ceased Period Huoyan Geese
Luan, Xinhong,Cao, Zhongzan,Xu, Wen,Gao, Ming,Wang, Laiyou,Zhang, Shuwei Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.7
Huoyan goose is a Chinese local breed famous for its higher laying performance, but the problems of variety degeneration have emerged recently, especially a decrease in the number of eggs laid. In order to better understand the molecular mechanism that underlies egg laying in Huoyan geese, gene profiles in the pituitary gland of Huoyan geese taken during the laying period and ceased period were investigated using the suppression subtractive hybridization (SSH) method. Total RNA was extracted from pituitary glands of ceased period and laying period geese. The cDNA in the pituitary glands of ceased geese was subtracted from the cDNA in the pituitary glands of laying geese (forward subtraction); the reverse subtraction was also performed. After sequencing and annotation, a total of 30 and 24 up and down-regulated genes were obtained from the forward and reverse SSH libraries, respectively. These genes mostly related to biosynthetic process, cellular nitrogen compound metabolic process, transport, cell differentiation, cellular protein modification process, signal transduction, small molecule metabolic process. Furthermore, eleven genes were selected for further analyses by quantitative real-time PCR (qRT-PCR). The qRT-PCR results for the most part were consistent with the SSH results. Among these genes, Synaptotagmin-1 (SYT1) and Stathmin-2 (STMN2) were substantially over-expressed in laying period compared to ceased period. These results could serve as an important reference for elucidating the molecular mechanism of higher laying performance in Huoyan geese.
The Experimental Animation and Contemporary Art
Luan Weili 중앙대학교 영상콘텐츠융합연구소 2014 TechArt :Journal of Arts and Imaging Science Vol.1 No.2
It is not enough to focus only on the development of mainstream animation and commercial animation, when China tries its best to develop animation education and industry. It ignores the vitality which the experimental and pioneering efforts bring to animation art. The media material experiments and the expressive languages of the experimental animation are suitable for animation education and therefore, call for dynamic application and promotion. Combination, collage, imitation and conversion are the same features of styling language which the experimental animation shares with the contemporary art. I recommend that we study the creative approaches and the expressive languages in the experimental animation and contemporary art and then gradually establish the complete theoretical system and practical principles.
Luan Shi,Zhuqing Liu,Wei Yang,Yaojun Li,Xiaodong Liu,Ran Tao 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.10
If a centrifugal impeller is in deep stall, it requires a large amount of additional energy to break free. As such, it is crucial to study the prediction method of impeller stall and establish its relationship with force and torque. This study employs a computational fluid dynamics numerical simulation method to analyze the flow field within the impeller of a centrifugal pump, while monitoring the changes in hydraulic torque of the blades. By examining the impeller’s internal flow field characteristics and external (energy performance) characteristics curves under different working conditions, the stall process was classified into three stages: germination, transition and stabilization. The evolution of stall cells under different stall stages was also analyzed. We utilized time-frequency conversion and analysis to extract characteristic parameters from instantaneous hydraulic torque results generated under different working conditions. A more effective model for predicting impeller stall stages was built by virtue of support vector machine algorithm. The proposed model exhibits improved feasibility and effectiveness in comparison to traditional prediction methods. It is expected to have significant implications for stable operation monitoring and safety protection of centrifugal pumps.