http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
The effect of LAMA and LABA on lung function in bronchiectasis patients
( Suyeon Lee ),( Yeon Mok Oh ),( Sei Won Lee ),( Jae Seung Lee ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Background: Bronchiectasis is a chronic lung disease characterized by coughing, sputum, and repeated bronchial infections with permanent bronchial dilatation. One of the treatment goal for bronchiectasis is maintaining or improving lung function. In practice, long-acting muscarinic antagonist (LAMA) or beta-agonist (LABA) inhaled bronchodilators are often used to treat bronchiectasis, but there is very low evidence to recommend their use. So the aim of this study is to evaluate the effectiveness of LAMA or LABA in bronchiectasis patients by comparing lung function before and after LAMA or LABA treatment. Methods: This study was a retrospective, observational study comparing lung function, before and after LAMA or LABA treatment. We analyzed the data of 230 bronchiectasis patients who were treated with LAMA or LABA for at least one month without any history of asthma or cigarette smoking. We similarly analyzed the data of 97 patients, after excluding those treated with antibiotics, steroids, or mucolytics. We identified the factors relating to the increase in FEV1 values after the treatment of LAMA or LABA with linear regression analysis. Results: Of 230 patients, 32.5% were male, and the median age was 60 years. Mean FEV1 was 53.5% of predicted value. After treatment with LAMA or LABA, we found improvement of FEV1 (P<0.001). The mean change in FEV1 was 5%±8.9% of the predicted value. After excluding the patients treated with antibiotics, steroids or mucolytics, we also found improvement of FEV1 (P<0.001), with a mean change of 5.7%±7.8%. The factors relating to the increase in FEV1 were mMRC dyspnea grade and baseline FEV1 value. The lower the mMRC dyspnea grade, the greater the change of FEV1 (P=0.005); the lower the baseline FEV1 value, the greater the change of FEV1 (P=0.0001). Conclusions: LAMA or LABA treatment might improve lung function in bronchiectasis patients.
Lee, Suyeon Korea Music Therapy Education Association 2005 인간행동과 음악연구 Vol.2 No.1
The purpose of this study was to investigate the effect of music listening, autogenic training, and music-assisted autogenic training on the quality of life, physiological and psychological relaxation responses, and daily living in a population of migraine patients. Forty migraine patients, ranging 20 to 60 years, were referred to the researcher by their physicians and participated in the study. A convenience control-group pretest-posttest design was employed. The participants were randomly assigned to one of four groups: music listening (ML), autogenic training (AT), music-assisted autogenic training (MAT), or a control group participants, with n = 10 participants per group. The participants in experimental groups received four 30-minute sessions with an assigned treatment, once a week during a 4-week experiment period. The participants in the control group continued their regular medical treatment as prescribed by the doctor without receiving any other relaxation treatment. However, they were still aware of the research and their responsibilities for the study. The Migraine Assessment (MIDAS) and Migraine-Specific Quality of Life (MSQOL) questionnaire were used to investigate a migraine patients' quality of life collected before and after the 4-week experiment for all subjects. The physiological and psychological relaxation responses of migraine patients were measured by relaxation levels and forehead temperature recorded before and after each treatment session for the participants in three treatment conditions. The effect of the relaxation treatments on daily living of migraine patients was examined through the frequency and intensity of migraine headaches, and the amount of medication taken for migraine headaches during the 4-week experiment as recorded in participants' diary for all participants. The results found significant differences from pre- to posttest on the MIDAS, MSQOL, and relaxation levels while no significant was found among the groups. The analysis of forehead temperature showed no significant difference from pre- to posttest and among the groups. A one-way ANOVA was performed on the frequency, intensity, and amount of medication taken for migraine headaches during the 4-week experiment period. While results yielded no significant difference among the groups, the data indicate that the participants in the three treatment groups reported fewer migraine headaches, lower degrees of headache intensity, and less medication taken for migraine headaches than participants in the control group. A conclusion drawn from this study is that music listening itself as a relaxation treatment, or as an adjunct to other relaxation techniques can be effective in the treatment of migraine headaches.
Lee, Suyeon,Han, Hye Seong,Seong, Dong Gi The Korean Society for Composite Materials 2022 Composites research Vol.35 No.3
Owing to advantages of polymeric materials for hydrogen tank liner like light-weight property and high specific strength, polymer based composites have gained much attention. Despite of many benefits, polymeric materials for fuel cell tank cause problems which is critical to applications as low gas barrier property, and poor processability when adding fillers. For these reasons, improving gas barrier property of polymer composites is required to study for expanding application fields. This work presents impermeable polymer nanocomposites by introducing thin barrier coating using layer by layer (LBL) deposition method. Also, bi-layered and quad-layered nanocomposites were fabricated and compared for identifying relationship between deposition step and gas barrier property. Reduction in gas permeability was observed without interrupting mechanical property and processability. It is discussed that proper coating conditions were suggested when different coating materials and deposition steps were applied. We investigated morphology, gas barrier property and mechanical properties of fabricated nanocomposites by FE-SEM, Oxygen permeation analyzer, UTM, respectively. In addition, we revealed the mechanism of barrier performance of LBL coating using materials which have high aspect ratio.
Suyeon Lee,Woo Sik Kim 한국세라믹학회 2019 한국세라믹학회지 Vol.56 No.6
Recently, E-glass fiber is the one of most widely used ceramic fiber for aerospace fields. Recycling technology for waste of wind power blades is arising issue for reasons of low manageability and high cost of wastes. Though glass fiber is perfectly dissolved in hydrofluoric acid, low cost for recycling and harmless to human is important for recycling of blades. Chemically melted glass fiber will be used as different purpose like accelerator of hardening for shotcrete. In this study, dissolution process of glass fiber is tested in NaOH solution at low temperatures. In addition, difference in diameter reduction of glass fiber is observed by various alkali concentration and reaction times, treatment temperatures using FE-SEM.
Lee, Suyeon,Kim, Kyoohyun,Kim, Hyunjin,Yeo, Sang-Yeob Korean Society of Environmental Biology 2013 환경생물 : 환경생물학회지 Vol.31 No.1
Oil spills have occurred throughout the years of industrialization and represent a global challenge as they affect vast areas of the ocean. The toxicity of crude oil to aquatic organisms has been extensively investigated, but the potential impacts of crude oil on vertebrate development remain largely unknown. Here, we investigated the effects of dispersants used in treating a recent oil spill, as well as that of crude oil, on vertebrates by using the zebrafish (Danio rerio) model species, which has been widely used in empirical studies of both early embryonic development and adult physiology. Chronic exposure to crude oil resulted in marked developmental abnormalities, including pericardial edema, abnormal trunk vessel development, retardation of axonal branching, and abnormal jaw development. Embryonic development was affected more severely by exposure to the oil-dispersant combination than to the oil alone. Thus, the zebrafish in vivo model system suggests that dispersant treatment can have detrimental developmental effects on vertebrates and its potential impact on marine life, as well as humans, should be carefully considered in clean-up efforts at the site of an oil spill.