제왕절개 분만율의 지역간 변이와 관련요인에 대한 연구

김혜경,이정운,박강원,문옥륜,Kim, Hye-Kyung,Lee, Jeon-Un,Park, Kang-Won,Moon, Ok-Ryun 대한예방의학회 1992 Journal of Preventive Medicine and Public Health Vol.25 No.3

The purpose of this study is to estimate cesarean section rate in Korea and analyze the socioeconomic variables and health resources which affect regional variation in the rate. Samples were drawn from the record of vaginal and cesarean section deliveries based upon insurance claim bills which have been submitted to the National Federation of Medical Insurance for the first three months, January through March, 1991. The results are obtained as follows : It was found that. cesarean section rate was increasing rapidly up to 23.1% in 1991. Cesarean section per 10 thousand insured people was 4.8 and the number of cesarean section per 10 thousand insured eligible($15{\sim}49$ years old) female was 7.6. The fee for normal delivery was 109,489 won and that for cesarean section was 390,024 won. The average days of hospitalization in normal delivery was 2.3 days, and those in cesarean section was 7.6 days. On the average cesarean section has a longer of stay as much as by 4.3 days and cost 3.6 times more than normal deliveries. Cesarean section rates vary among medical facilities 19.8% at clinics 37.6% in small-scale hospitals, and 29.1% in general hospitals. The regional variation of cesarean section rates was also fairly prominent. The South Cheju Gun has the highest rate of cesarean section, 56.2%. Meanwhile no cesarean section cases has been reported in Sunchang Gun during the period of this study. The variation is noted among provinces. The rate for Cheju province has been 3.4 times higher than that for Chunnam. The number of cesarean section per 10 thousand insured people vary greatly among regions, too. This study has found that there exists significant regional variations among various geographic units in terms of average length of stay, average cost, number of obsretricians and number of beds. Multiple regression analysis was done to identify factors explaining the regional variance of various cesarean section rates : In the urban areas, no significant explaining variables were noted except the number of beds for the dependent variable of cesarean section cases per 10 thousand insured eligible females. The smaller the number of bed, the more cases of cesarean section was noted for an urban area. The is mostly because the rate of cesarean section is higher in medium-size hospitals than in large general hospitals. In the rural areas, the factor of education has been found significant for all three deplendent variables. The higher the educational level, the rate of cesarean section is most likely to rise. An income variable measured by the amount of monthly insurance contribution has been identified a powerful predictor in explaining the valiance of cesarean section rates. The same has been noted for the number of obstetricians. Similar findings are observed for the country as a whole. The income level has veen found as the most powerful explaining factor in the regional variance of cesarean section rates. In general the rate is higher in the urban areas, and lower in the area with more small hospitals. As this is the initial attempt to identify the factors relevant to the regional difference in the rates of cesarean section, more elaborated study is urgently required.

Development of T-cell Based Reporter Assay System to Identify Immunomodulators from Herbal Medicine

Jeon, Won-Kyung,Hwang, Ji-Sun,Kwon, Ho-Keun,Lee, Chung-Gu,Im, Sin-Hyeog,Ko, Byoung-Seob The Korean Society for Applied Biological Chemistr 2009 Applied Biological Chemistry (Appl Biol Chem) Vol.52 No.6

To evaluate immunomodulators from herbal medicines that affect the expression of IL-10 and TNF-${\alpha}$, we developed a cell-based high throughput screening system and tested 17 kinds of herbal medicine. We found that extracts of Coptidis Rhizoma can be used to stimulate TNF-${\alpha}$ and IL-10 expression.

The Analysis on the Deformation of Electrostrictive Polymer Film with respect to Time under Constant Voltage

Kyung Chul Park,Ji Won Yun,Jae Wook Jeon,Hyoukryueol Choi,Hunmo Kim,Jae-Do Nam 제어로봇시스템학회 2001 제어로봇시스템학회 국제학술대회 논문집 Vol.2001 No.10

Design of 32-bit RISC Processor with Reconfigurable Coprocessor

Jeon, Seung-Ryong,Kim, Nam-sub,Kim, Jin-Sang,Cho, Won-Kyung 경희-다반 ASIC 설계교육센터 2002 경희-다반 ASIC센터 논문집 Vol.3 No.-

For newly growing multimedia applications, the architecture of traditional RISC microprocessors is not sufficient. In this thesis, an architecture which integrates a DSP functional reconfigurable unit into a pure RISC architecture is studied and designed to improve the ability of processing multimedia data. Special RISC instructions are included for reconfigurable processor functions.

Conception and case studies of underachievement and Iearning disa bilities among the gifted

JEON, KYUNG-WON 광주대학교 사회과학연구소 1991 社會科學硏究 Vol.1 No.-

미성취영재와(Gifted Underachiever) 학습장애영재(Learning Disabled)는 아주 애매모호한 개념이다. NACHC정의에 의하면 학습장애아란 이해하는데 가장 기초적인 심리과정에서 혼란을 보이며, 이러한 현상은 듣거나, 생각하거나, 말하거나, 읽거나, 쓰거나, 철자법에 있어서나, 산수계산을 할 때 명백하게 나타난다고 했다. 학습장애 영재란 위와 같이 학습 장애적인 면을 지니고 있다. 반면에 미성취 영재란 지적인 능력이 뛰어나고, 학습 장애적인 면은 나타나지 않으나 능력만큼 성취를 제대로 못하는 경우이다. 본 연구에서는 학습장애영재와 미성취 영재의 특성과 원인을 두명의 학습장애영재와 한명의 미성취 영재에 관한 사례연구를 통해 알아보고자 했다. 두명의 학습장애 영재는 미국의 Rimm 박사가 운영하는 가족성취 임상 연구소(Family Achievement Clinic Center) 에서 치료를 받았던 사례이고, 한명은 한국의 미성취 영재로서 연구자와 몇 차례의 상당과 인터뷰에 응했던 사례로서 그들의 지능의 양상, 성취도, 가족배경, 출생배경등을 고찰했다. 연구결과 미성취 영재의 경우는 학습장애의 현상이 전혀 없는 경우로 그 원인은 가족간의 문제나 학업성취에 관한 부모의 기대가 높았을 경우이며, 학습장애영재의 경우는 두뇌손상, 두뇌 최소기능 장애, 난독증 등이 그 원인으로 밝혀졌다. 지능적인 측면에서는 학습장애의 경우 언어적 지능(Vebal IQ)과 동작성 지능 (Performance IQ)간에 차이가 있음에 반해 미성취 영재의 경우는 그 차이가 별로 없었다. 또한, 2명의 학습장애 영재는 기호화(Coding) 영역에서 낮은 점수를 보였는데, 이는 Silverman(1989)과 Schiff, Kaufman, kaufman (1981)등의 선행연구등과 같은 결과였다. 이 연구결과 몇가지 시사점을 살펴보면 다음과 같다. 첫째, 학습장애 영재가 학업이나 창의적인면에서 의례히 미성취 현상을 나타낸다고 볼수는 없다. 에디슨이나 아인슈타인과 같이 학습장애 이면서 위대한 업적을 남긴 사례는 많이있다. 그러므로 학습장애 영재가 미성취 영재로 잘 못 판별되는 일이 없도록 해야한다. 둘째, 학습장애 영재와 미성취 영재의 원인은 각기 다르지만 두 그룹이 보이는 특성은 공통적인 측면이 있다. 낮은 자아개념, 사회적 고립적인 성격, 주위산만적인 성격등이 그 특성이다. 그러므로 외형적인 특성만으로 학습장애아라고 판정하는것는 바람직하지 못하다. 셋째, 미성취 영재인 경우는 학습 장애적인 면에 있는지 사고과정 중 심적인(Process-oriented) 검사를 거쳐야 한다. Illinois Test of Psycholinguistic Abilities(ITPA)나 Marianne Frostig Developmental Test of Visual Perception(DTVP)같은것을 사용하는것이 좋다. 넷째, 영재를 담당하는 교사와 특수학급 교사와는 밀접한 대화가 이루어져야한다. 영재를 담당하는 교사는 학생중에 학습장애가 있다는 것을 그리고, 특수아를 지도하는 교사는 장애학생중에 영재가 있다는 것을 간과하는 경우가 많으므로 긴밀한 대화가 필요하다. 끝으로, 학습장애성이 있는 미성취아나, 학습장애성이 없는 미성취아나 또는 학습장애가 있으면서 뛰어난 성취를 하는 경우이든, 이들에게는 개별화된 학습(Individualized Instruction)이 되야한다.

A study on self-concept, intelligence, and achievement of scientifically gifted high snhool boys(SGB) and girls(SGG0

Jeon, Kyung-Won 광주대학교 사회과학연구소 1991 社會科學硏究 Vol.1 No.-

영재의 자아개념(self-concept)과 성(gender)의 관계와 관련된 연구결과는 일관성이 없고, 한국은 물론 외국에서도 과학영재 고등학생을 대상으로 한 연구는 실로 드물다. 그러므로 본 연구의 목적은 과학고등학교 여학생과 남학생간의 자아개념, 지능, 성취도에 차이가 있는가, 그리고 자아개념, 지능, 성취도 세 변인들 사이에 상관관계를 알아보고자 했다. 자아개념검사, 지능검사, 표준화, 성취도검사를 평균 IQ 145인 과학고등학교 1, 2, 3학년 학생중 남학생 34명, 여학생 34명에게 실시했다. 자아개념 검사도구지는 자아평가, 총자아긍정, 자아긍정, 자아수용, 자아행동, 신체적자아, 도덕적자아, 성격적자아, 가정적자아, 사회적자아 등 10개 요인으로 구성되어 있다. 연구결과는 자아개념의 10개 하위요인 중에서 자아평가(self-criticism) 영역에서 남녀간에 유의한 차이를 보였다 : 남학생이 여학생보다 자아비판적 특성이 높았다.(t=1.99, p<0.05). 지능 총점수 (t=3.84, p<0.001) 뿐 아니라, 하위요인인 공간지각력(t=3.51, p<0.001)과 수학 (t=2.67, p<0.01)에도 남녀간에 유의한 차이를 보였다. 그러나 성취도는 남녀간에 유의한 차이가 발견되지 않았다. 총 표집대상 68명 (M=34, F=34)에게 자아개념과 지능변인간에 관계를 분석하기 위하여 상괸계수를 구해본 결과 총지능점수와 개인적자아(Personal self)와 가족적인 자아(Family self)에서 alpha=0.01 수준에서 의미있는 관계를 보여주었다. 자아개념과 성취도, 지능과 성취도 변인간에 상관관계는 통계적으로 의미있는 관계를 보여주지 못했다. 세 변인간의 낮은 상관관계는 지능이 높다고해서 긍정적 자아개념을 갖고 있거나 높은 성취도를 보이는것도 아니라는것을 보여주고있다. 본 연구를 통해서, 과학고등학교 프로그램은 남녀 학생들의 긍정적인 자아개념을 증진하기 위해서 각각 다른 자아개념 영역에서 노력을 기울여야 한다고 제안되어졌다. The relationship between gender and self-concept of the gifted youngsters was found somewhat controversial, and research is minimal in the area of self-concept of scientifically gifted high school students in Korea as well as in other countries. Therefore, the purpose of this study is to discover whether or not there are significant differences between scientifically gifted high school boys (SGB) and girls (SGG), in relation to self-concept, intelligence, and achievement, and whether or not there are relations among intelligence, achievement, and self-concept. The Korean adapted self-concept instrument, a group intelligence test and standardized achievement test were administered to 68, 10th through 12th grade scientifically gifted high school students of superior intelligence who have high IQ scores of 145. There was only one significant sex difference for the subscale of self-criticism out of 10 measures of self-concept: SGB have a higher score on self-criticism subscale than SGG (t = 1.99, p.0<0.05). There were also sex differences for the total intelligence (t=3.64, p<0.001), Spacial ability (t=3.51, p<0.001), and Math (t=2.67, p<0.01). However, no sex-differences on achievement were found between SGB and SGG. Two significant correlations between self-concept and intelligence referred to the positive relationship of a total score of intelligence with Personal self (r=0.3097^*) and Family Self (r=0.2847^*) for the total population. There were no significant correlations between self-concept and achievement and no correlations were significant between intelligence and achievement for the total population, SGB and SGG. Implications are suggested for school programmins designed to facilitate the positive self-concept of gifted high school boys and girls differently.

Isolation of a Calcium-binding Substance from Anchovy

Jeon, So-Jeong,Kim, Won-Gon,Song, Kyung-Bin The Korean Society for Applied Biological Chemistr 2010 Applied Biological Chemistry (Appl Biol Chem) Vol.53 No.4

Dried anchovy (Engraulis japonica) was extracted using hot water and filtered with a YM-3 membrane to isolate a calcium binding substance. The membrane filtered solution was fractionated using gel permeation chromatography, ion exchange chromatography, reverse-phase high performance liquid chromatography, and fast protein liquid chromatography to detect calcium-binding substances. The isolated substance was identified as adenosine by nuclear magnetic resonance spectroscopy.

Development of Transgenic Tall Fescue Plants Expressing 2-Cys Prx Gene and Their Performance in Response to Oxidative Stresses

Kyung-Hee Kim,Choong-Hoon Park,Iftekhar Alam,Ki-Won Lee,Dong-Gi Lee,Chan-Ho Jeon,Sang-Soo Kwak,Byung-Hyun Lee 한국초지조사료학회 2008 한국초지조사료학회 학술대회논문집 Vol.2008 No.09

Antifungal miconazole induces cardiotoxicity via inhibition of APE/Ref-1-related pathway in rat neonatal cardiomyocytes.

Won, Kyung-Jong,Lin, Hai Yue,Jung, Soohyun,Cho, Soo Min,Shin, Ho-Chul,Bae, Young Min,Lee, Seung Hyun,Kim, Hyun-Jung,Jeon, Byeong Hwa,Kim, Bokyung Academic Press 2012 Toxicological sciences Vol.126 No.2

<P>Effects of miconazole, an azole antifungal, have not been fully determined in cardiomyocytes. We therefore identified the transcriptome in neonatal rat cardiomyocytes responding to miconazole using DNA microarray analysis and selected a gene and investigated its role in cardiomyocytes. Miconazole dose-dependently increased the levels of superoxide (O(2)(-)) and apoptosis in cardiomyocytes; these increases were inhibited by treatment with antioxidants. The DNA microarray revealed that 4163 genes were upregulated and 4829 genes downregulated by more than threefold in miconazole-treated cardiomyocytes compared with the vehicle-treated control. Moreover, redox homeostasis-, oxidative stress-, and reactive oxygen species (ROS)-related categories of genes were strongly affected by miconazole treatment. Among genes overlapped in all these categories, apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1), a redox-related gene, was prominent and was diminished in the miconazole-treated group. Changes in the O(2)(-) production and apoptosis induction in response to miconazole were inhibited in cardiomyocytes transfected with adenoviral APE/Ref-1. Overexpression of APE/Ref-1 reversed the reduction in beating frequency induced by miconazole. Our results demonstrate that miconazole may induce rat cardiotoxicity via a ROS-mediated pathway, which is initiated by the inhibition of APE/Ref-1 expression. This possible new adverse event in cardiomyocyte function caused by miconazole may provide a basis for the development of novel antifungal agents.</P>

Anti-platelet Activity of Tissue-cultured Mountain Ginseng Adventitious Roots in Human Whole Blood

Won Kyung Jeon,Bo Kyung Yoo,Yeong Eun Kim,Sun Ok Park,Eun-Joo Hahn,Kee-Yoeup Paek,Byoung Seob Ko 한국식품과학회 2008 Food Science and Biotechnology Vol.17 No.6

Present study investigated the effects of the 70% ethanol extracts of tissue-cultured mountain ginseng (TCMG), Korean red ginseng (KRG), and Panax ginseng (PG) on agonist-induced platelet aggregation and activation in human whole blood. The IC?? values for TCMG, KRG, and PG were 1.159, 3.695, and 4.978 ㎎/㎖ for collagen-induced aggregation, 0.820, 2.030, and 4.743 ㎎/㎖ for arachidonic acid-induced aggregation, and 1.070, 2.617, and 2.954 ㎎/㎖ for ADPinduced aggregation, respectively. Also, this study assessed the effects of the most active extract, TCMG, on markers of platelet activation by determining receptor expression on platelet membranes in healthy subjects, including expression of GPIIb/IIIa-like (PAC-1) and P-selectin (CD62), by flow cytometry. A significant decrease in PAC-1 expression (p=0.018) was observed in the presence of TCMG. These results show that TCMG has potent anti-platelet activity.