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( Hyung Oh Kim ),( Chun Gyoo Ihm ),( Tae Won Lee ),( Kyung Hwan Jeong ),( Seul Ki Kim ),( Ji Yun Park ),( Jin Sug Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: We report a rare case of CAPD peritonitis caused by Ochrobacterium anthropi. Introductions: Among the continuous ambulatory peritoneal dialysis(CAPD) patients, peritonitis is one of the most commonly taken complications, and also the general cause of dialytic modality exchange to hemodialysis. Usual pathogens of CAPD peritonitis may be bacteria, fungi, mycobacteria. Coagulase negative staphylococci, S. aureus, campylobacter, pseudomonas are common reported pathogens among the bacteria, of CAPD peritonitis cases, meanwhile candida is among fungi. Ochrobacterium anthropi is one species of Brucellaceae, which is rare pathogen of human disease. Case (Methods and results): 73 years old female, who was on CAPD due to diabetic end stage renal disease visited Kyung-Hee University hospital with intermittent abdominal pain. Body fi uid analysis showed increased white blood cell(WBC) count of 26,750/mm3 with her peritoneal fi uid. Culture study with peritoneal fi uid suggested O. anthropi, and DNA sequencing with PCR was consistent with O. anthropi. Intraperitoneal ceftazidime and cefazolin were administrated as empirical antibiotics. Ceftazidime resistance was noted with the result of antibiotics sensitivity test at 7th day of hospitalization, and antibiotics were changed into intraperitoneal gentamicin, which showed sensitivity to the pathogen. CAPD catheter removal and antibiotics re-exchange into imipenem and cefazolin, which were other sensitive antibiotics by the sensitivity test, were done since clinical manifestation and peritoneal fi uid WBC count was repeatedly improved and aggravated. The patient discharged with improved lab test results and resolving clinical symptoms afterward. Conclusions: We presentators report rare case of CAPD peritonitis with pathogen of O. anthropi. The pathogen of the case confi rmed by classical microbiologic, and molecular biologic Methods: The patient was unable to treat only with antibiotics, thus CAPD catheter, which might be act as colonizing source, was removed, and the disease resolved.
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김재필(Jae Phil Kim),조대옥(Dae Ok Cho),고경식(Kyung Sik Ko),안재형(Jai Hyung Ahn),이태원(Tae Won Lee),임천규(Chun Gyoo Ihm),김명재(Myung Jae Kim) 대한내과학회 1995 대한내과학회지 Vol.49 No.1
N/A Objectives: Renal transplantation is a major therapeutic advance for patients with chronic renal failure. But recipients of renal transplantation are prone to infection with both common and unusual organisms. And infectious diseases remain a major cause of morbidity and mortality in renal transplant recipients. This study was to analyze the infections in renal transplant recipients; its occurrence according to sites and organisms; comparison among immunosuppressive agents; prognostic differences of urinary tract infections(UTI) between those developed during 1 month after transplantation and those not developed; graft outcome; and patients mortality. Mothods: 181 renal transplant recipients were examined. They received renal transplantion between january 1979 and December 1992 at the Kyung-Hee University Hospital. 158 of them received transplantation from living-related donors, 22 from living-unrelated donors, and 1 from cadaver donor. Their age at the time of transplantation ranged from 14 to 66 years(mean 35.6 years), and the male to female ratio was 2.3: 1. The observation period ranged from 1 to 144 months(41.26±31.71, mean±S. D.). Results: 1) 110 recipients(60.7% of total) had 232 episodes of infectious complications whereas 71(39.3% of total) had no infectious episodes. About half of infectious episodes(128 episodes, 55.2% ) occurred during 1 month after transplantation. 2) The most common site of infection was urinary tract(138 episodes, 59.2%) whth the next sites coming in this order, bacteremia(32 episodes, 13.8%), pulmonary(21 episodes, 9.1%), and skin(21 episodes, 9.1%). 3) The causative organisms of UTI ranked in this order E. coli 21.7%, staphylococcus spp 14.5%, and pseudomonas spp 13.0%. 4) The causative organisms of bacteremia ranked in this order E. coli 34.4% salmonella spp 18.8%, pseudomonas spp 12.5 %, and staphylococcus spp 12.5%. 5) There was no significant differences of infectious episodes among immunosuppressive regimens. 6) Early UTI group(UTI occurred during 1 month after transplantation) recorded significantly higher incidence of urinary tract infections after 1 month that followed than non-UTI group. But there was no differences between two groups on graft and patients outcome. 7) The major cause of death was life-threatening infections(63.2 %). Conclusion: Most infections due to various organisms may occur during 1 month after transplantation. And still they constitute a major cause of death in renal transplant recipients.
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S-470 Relationships between blood pressure and clinico-pathological findings in IgA nephropathy
( Hyung-seok Ihm ),( Da-rae Kim ),( Jin-sug Kim ),( Kyung-hwan Jeoung ),( Tae-won Lee ),( Chun-gyoo Ihm ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Objective: Several factors contribute to the development of hypertension in patients with IgA nephropathy (IgAN). This study was conducted to find the relationships between baseline blood pressure (BP) and clinico-pathological findings in patients with IgAN and normal renal function. Design and Method: Clinico-pathological findings were analyzed in a total of 163 patients with IgAN and serum creatinine ￡ 1.1 mg/dL from The Kyung-Hee Cohort of Glomerulonephritis. The glomerular surface area (GSA) was determined using imaging analysis software. The serum and urine angiotensinogen (AGT) concentrations were measured using human ELISA kits.?Results: Mean serum creatinine concentration was 0.86 (0.5~1.1) mg/dL. Systolic BP was ≥ 130 mmHg in 72 patients (44%) and ≥ 140 mmHg in 42 (26%). Patients with systolic BP ≥ 130 mmHg as compared with those <130 mmHg had higher GSA and tubulointerstitial fibrosis and showed worse follow-up clinical findings: higher concentrations of serum creatinine, larger amount of proteinuria and lower levels of GFR. Systolic BP was positively correlated with age, baseline and follow-up proteinuria, serum uric acid concentrations and IgM deposit and negatively with follow-up GFR and the slope of change in 1/serum creatinine for 2 years, while it has no significant relationships with serum and urine AGT and 24 hour urinary sodium excretion. Conclusions: This study showed that systolic BP was associated with renal progression and pathological findings, glomerulomegaly and tubulointerstitial fibrosis, in patients with IgAN.
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Acute Energy Expenditure to Concurrent Aerobic and Hydraulic Resistance Exercise in Obese Women
( Kyung Hee Kim ),( Hyun Min Choi ),( Ho Sung Nho ),( Won Il Park ),( Jong Mok Chun ),( Chan Ho Kim ),( Chan Ho Park ),( Jong Kyung Kim ) 한국운동영양학회 2010 Physical Activity and Nutrition (Phys Act Nutr) Vol.14 No.4
It has been reported that combining both hydraulic resistance exercise and aerobic exercise (PACE) improves cardiorespiratory fitness and muscular strength in non-obese individuals. This study examined the effect of PACE training in obese women on energy expenditure during moderate self-selected intensity exercise. We tested the hypothesis that PACE training would elicit greater energy expenditure than stationary cycle exercise. Ten obese women completed a maximal exercise test. On separate days, all participants performed a submaximal PACE and a stationary cycle exercise trial. Submaximal energy expenditure (6.2±0.4 vs. 5.5±0.4 kcal/min), oxygen uptake (20.3±0.75 vs. 18.1+0.57 ml/kg/min), heart rate (142±5 vs. 136±6 bpm), percentage of oxygen uptake reserve (64.5+5 vs. 55.4±3%), and percentage of maximal heart rate 79±4 vs. 76±4%) were significantly higher during PACE compared to cycling exercise. Results suggest that self-selected PACE training optimizes energy expenditure during submaximal intensity exercise in obese individuals.
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Effect of Red Pepper Seeds Powder on Lipid Composition in Rats Fed High-FatㆍHigh-Cholesterol Diets
Won-Young Song,Sung-Sik Chun,Kyung-Hyung Ku,Jeong-Hwa Choi 한국식품영양과학회 2010 Preventive Nutrition and Food Science Vol.15 No.3
The purpose of the present study was to evaluate the effects of red pepper seeds powder on lipid metabolism in rats fed high fatㆍhigh cholesterol diet. Rats were divided into five experimental groups: normal diet group, high fatㆍhigh cholesterol diet group, high fatㆍhigh cholesterol diet with 5% red pepper seeds powder supplemented group (SA group), high fatㆍhigh cholesterol diet with 10% red pepper seeds powder supplemented group (SB group) and high fatㆍhigh cholesterol diet with 15% red peeper seeds powder supplemented group (SC group). The serum triglyceride (TG) and cholesterol contents, and LDL-cholesterol and atherogenic index (AI) of the red pepper seed powder supplemented groups were significantly decreased compared to the HF group. The serum HDL-cholesterol contents of the red pepper seed powder supplemented groups were increased compared to the HF group. However, there was no significant difference in the serum HDL-cholesterol among all experimental groups. The hepatic TG and cholesterol contents of the red pepper seed powder supplemented groups were significantly decreased compared to the HF group. The fecal total cholesterol and triglyceride contents of the red pepper seeds powder supplemented groups were significantly increased compared to the HF group. These results suggest that supplementation of red pepper seed powder may have a pronounced impact on markers of lipid metabolism in serum and liver of rats fed high fatㆍhigh cholesterol diets.
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Fracture patterns in the maxillofacial region: a four-year retrospective study
Kyung-Pil Park,Seong-Un Lim,Jeong-Hwan Kim,Won-Bae Chun,Dong-Whan Shin,Jun-Young Kim,Ho Lee 대한구강악안면외과학회 2015 대한구강악안면외과학회지 Vol.41 No.6
Objectives: The facial bones are the most noticeable area in the human body, and facial injuries can cause significant functional, aesthetic, and psy- chological complications. Continuous study of the patterns of facial bone fractures and changes in trends is helpful in the prevention and treatment of maxillofacial fractures. The purpose of the current clinico-statistical study is to investigate the pattern of facial fractures over a 4-year period. Materials and Methods: A retrospective analysis of 1,824 fracture sites was carried out in 1,284 patients admitted to SMG-SNU Boramae Medical Center for facial bone fracture from January 2010 to December 2013. We evaluated the distributions of age/gender/season, fracture site, cause of injury, duration from injury to treatment, hospitalization period, and postoperative complications. Results: The ratio of men to women was 3.2:1. Most fractures occurred in individuals aged between teens to 40s and were most prevalent at the middle and end of the month. Fractures occurred in the nasal bone (65.0%), orbital wall (29.2%), maxillary wall (15.3%), zygomatic arch (13.2%), zygomaticomaxillary complex (9.8%), mandibular symphysis (6.5%), mandibular angle (5.9%), mandibular condyle (4.9%), and mandibular body (1.9%). The most common etiologies were fall (32.5%) and assault (26.0%). The average duration of injury to treatment was 6 days, and the average hospitalization period was 5 days. Eighteen postoperative complications were observed in 17 patients, mainly infection and malocclusion in the mandible. Conclusion: This study reflects the tendency for trauma in the Seoul metropolitan region because it analyzes all facial fracture patients who visited our hospital regardless of the specific department. Distinctively, in this study, midfacial fractures had a much higher incidence than mandible fractures.
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