http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Kim, Su-Jung,Kim, Hong-Gyum,Kim, Byung-Chul,Kim, Kyunghoon,Park, Eun-Hee,Lim, Chang-Jin The Microbiological Society of Korea 2004 The journal of microbiology Vol.42 No.3
Transcriptional regulation of the Schizosaccharomyces pombe y-glutamylcysteine synthetase (GCS) gene was examined using the two GCS-lacZ fusion plasmids pUGCS101 and pUGCS102, which harbor 607 bp and 447 bp upstream regions, respectively. The negatively-acting sequence was located in the -607 - -447 bp upstream region of the GCS gene. The upstream sequence responsible for induction by menadione(MD) and L-buthionine-(S, R)-sulfoximine (BSO) resides in the -607 - -447 bp region, whereas the sequence which codes for nitric oxide induction is located within the -447 bp region, measured from the translational initiation point. Carbon source-dependent regulation of the GCS gene appeared to be dependent on the nucleotide sequence within -447 bp region. The transcription factor Papl is involved in the induction of the GCS gene by MD and BSO, but not by nitric oxide. Induction of the GCS gene occurring due to low glucose concentration does not depend on the presence of Pap1. These data imply that induction by MD and BSO may be mediated by the Pap1 binding site, probably located in the -607 - -447 region, and also that the nitric oxide-mediated regulation of the S. pombe GCS gene may share a similar mechanism with its carbon-dependent induction.
Kim Beom Joon,Choi Arum,Kim Hwan Soo,Oh Jin-Hee,Lee Jae-Young,Kim Sukil,Han Ji-Whan,Kim Kyunghoon,Kim Hyun Hee 대한의학회 2022 Journal of Korean medical science Vol.37 No.20
Background: The impact of the coronavirus disease 2019 (COVID-19) pandemic on Kawasaki disease (KD) has not yet been established. We investigated changes in the observed number and severity of KD cases and accompanying coronary artery complications during the COVID-19 pandemic in Korea. Methods: This retrospective observational study included patients aged < 18 years with acute-phase KD diagnosed between March 2018 and February 2021. Data were extracted from the Clinical Data Warehouse that houses data from five affiliated university hospitals in Korea. We analyzed changes in the number of patient admissions and clinical characteristics, including cardiac complications, before and after the onset of the COVID-19 pandemic. Results: A total of 475 admissions were included in the analysis. After March 2020, we observed a significant decrease of 33% in the number of hospitalizations for KD compared with the average number of hospitalizations during the previous 2 years. The number of admissions per month significantly decreased by 7.9 persons/month (95% confidence interval, −13.8 to −2.0; P < 0.05) compared with that before COVID-19. By contrast, the proportion of patients aged < 1 year with KD increased. The proportion of patients with refractory KD and the rate of cardiac complications did not change significantly. Conclusion: Since the onset of the COVID-19 pandemic, the total number of hospital admissions for KD has decreased in Korea. Although the proportion of admissions of infants aged < 1 year increased, no changes were observed in clinical courses and complications.
도로변 초미세먼지의 실시간 질량농도 및 부피농도 측정을 이용한 시간별 밀도 분석-광흡수 eBC에 대한 OPS 보정 중심
김은영(Eunyoung Kim),서석준(Seokjun Seo),김선문(Sunmoon Kim),정성운(Sungwoon Jung),이용민(Yongmin Lee),오세호(Sea-Ho Oh),박규태(Gyutae Park),김경훈(Kyunghoon Kim),김정화(Jounghwa Kim),홍유덕(Youdeog Hong),이태형(Taehyoung Lee),배민석(Mi 한국대기환경학회 2018 한국대기환경학회지 Vol.34 No.6
Engineering nanowrinkled microfibers composed of eggshell membrane and graphene
Park, Sunho,Choi, Kyoung Soon,Kim, Woochan,Lee, Dohyeon,Kim, Daun,Kim, Myung-Sun,Kim, Kyunghoon,Kim, Jangho Elsevier 2018 Materials letters Vol.229 No.-
<P><B>Abstract</B></P> <P>We present a facile method for designing and manipulating eggshell membrane-based nanowrinkled microfibers (EMNMs) using graphene and a spin-coating technique. Graphene is simply spin-coated on the eggshell membrane to form multiscale structures of nanowrinkled microfibers. We demonstrate that the EMNMs combine the unique properties of the raw eggshell membrane and graphene, such as micro- and nanoscale hierarchical morphologies, specific crystalline structures, and surface wettability. We also show that the properties of the EMNMs can be controlled by adjusting the concentration of graphene.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Nanowrinkled microfibers composed of eggshell membrane and graphene are fabricated. </LI> <LI> The properties of the prepared nanowrinkled microfibers are investigated. </LI> <LI> The microfiber properties can be controlled by adjusting the graphene concentration. </LI> </UL> </P>
( Kyunghoon Kim ) 정보통신정책학회 2019 정보통신정책연구 Vol.26 No.3
This study is concerned with factors affecting start-ups’ survival, and with predicting their survival probability. A new proportional hazard model is proposed for analyzing the survival of information and communications technology (ICT) start-ups. This model overcomes the limitations of existing survival models in their utilization of information about firms’ activities, stemming from the fact that those models manipulate observations only in a continuous-time horizon. A discrete-time proportional hazard model is proposed to account exhaustively for firms’ activities within the study period. To show the superiority of the proposed discrete-time proportional hazard model over a benchmark continuous-time proportional hazard model, both models are applied to a clinical dataset and their log-likelihood values are compared. The proposed model is found to be better in terms of goodness-of-fit and predictive performance.
Kim Hong-Gyum,Kim Byung-Chul,Kim Kyunghoon,Park Eun-Hee,Lim Chang-Jin The Microbiological Society of Korea 2004 The journal of microbiology Vol.42 No.4
In a previous study, a gst gene was isolated from the fission yeast Schizosaccharomyces pombe. This gene was dubbed gstI, and was characterized using the gstI -lacZ fusion plasmid pYSH2000. In this work, four additional fusion plasmids, pYSHSDl, pYSHSD2, pYSHSD3 and pYSHSD4, were constructed, in order to carry (respectively) 770, 551, 358 and 151 bp upstream regions from the translational initiation point. The sequence responsible for induction by aluminum, mercury and hydrogen peroxide was located in the range between -1,088 and -770 bp upstream of the S. pombe gstI gene. The same region was identified to contain the nucleotide sequence responsible for regulation by Papl, and has one putative Papl binding site, TTACGTAT, located in the range between $-954\~-947$ bp upstream of the gstI gene. Negatively acting sequences are located between -1,088 and -151 bp. These findings imply that the Papl protein is involved in basal and inducible transcription of the gstI gene in the fission yeast S. pombe.
Kim, Minseong,Shim, Jaehun,Yu, Kyunghoon,Kim, Jiwon korean Academy of Physical Therapy Rehabilitation 2016 Physical therapy rehabilitation science Vol.5 No.4
Objective: The purpose of this study was to compare the effect of ball kicking dual task gait training with the addition of a cognitive task with general treadmill gait training (TGT) on gait speed, gait endurance, functional gait, balance and balance confidence in patients with chronic hemiparetic stroke. Design: Randomized controlled trial. Methods: Fourteen stroke patients who volunteered to participate in this study were randomly divided into two groups with seven patients in each group: ball kicking dual task training (DTT) group and TGT group. The DTT group received ball kicking DTT with cognitive tasks consisted of three stages and the TGT group received TGT using normal walking speed, respectively, for 30 minutes per day 3 days per week for 4 weeks. Outcome assessments were made with the 10-meter walking test (10MWT), 6-minute walking test (6MWT), functional gait assessment (FGA), Berg balance scale (BBS), timed up and go test (TUG), and the activities-specific balance confidence (ABC) scale. Results: The DTT group showed more significant improvement in the 10MWT, 6MWT, FGA, BBS, TUG, and ABC than the TGT group (p<0.05). In addition, within groups comparison showed significant improvement in all variables (p<0.05). Conclusions: The findings suggest that both ball kicking dual task gait training and TGT improve gait performance and balance in patients with chronic hemiparetic stroke. However, ball kicking dual task gait training results showed more favorable outcomes than TGT for chronic hemiparetic stoke patients.