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Risk factors and outcomes of acute renal infarction
( Jihyun Yang ),( Jun Yong Lee ),( Young Ju Na ),( Sung Yoon Lim ),( Myung Gyu Kim ),( Sang Kyung Jo ),( Wonyong Cho ) 대한신장학회 2016 Kidney Research and Clinical Practice Vol.35 No.2
Background: Renal infarction (RI) is an uncommon disease that is difficult to diagnose. As little is known about clinical characteristics of this disease, we investigated its underlying risk factors and outcomes. Methods: We performed a retrospective single-center study of 89 patients newly diagnosed with acute RI between January 2002 and March 2015 using imaging modalities. Clinical features, possible etiologies, and long-term renal outcome data were reviewed. Results: The patients`` mean age was 63.5 ± 15.42 years; 23.6% had diabetes and 56.2% had hypertension. Unilateral and bilateral involvements were shown in 80.9% and 19.1% of patients, respectively; proteinuria and hematuria were reported in 40.4% and 41.6%, respectively. Cardiovascular disease was the most common underlying disease, followed by renal vascular injury and hypercoagulability disorder. Fourteen patients had no specific underlying disease. At the time of diagnosis, acute kidney injury (AKI) was found in 34.8% of patients. Univariate analysis revealed diabetes mellitus (DM), leukocytosis, and high C-reactive protein (CRP) as significant risk factors for the development of AKI. On multivariate analysis, DM and high CRP levels were independent predictors for AKI. During follow-up, chronic kidney disease developed in 27.4% of patients. Univariate and multivariate Cox regression analyses showed old age to be an independent risk factor for this disease, whereas AKI history was a negative risk factor. Conclusion: DM patients or those with high CRP levels should be observed for renal function deterioration. Clinicians should also monitor for RI in elderly patients.
( Jihyun Yang ),( Geun Eog Ji ),( Myeong Soo Park ),( Yeong-je Seong ),( Yoon Sook Go ),( Hee Young Lee ),( Yina Fang ),( Myung-gyu Kim ),( Se Won Oh ),( Won Yong Cho ),( Sang-kyung Jo ) 대한신장학회 2021 Kidney Research and Clinical Practice Vol.40 No.4
Background: A healthy microbiome helps maintain the gut barrier and mucosal immune tolerance. Previously, we demonstrated that acute kidney injury (AKI) provoked dysbiosis, gut inflammation, and increased permeability. Here, we investigated the renoprotective effects of the probiotic Bifidobacterium bifidum BGN4 and the underlying mechanisms thereof. Methods: C57BL/6 mice were subjected to bilateral renal ischemia-reperfusion injury (IRI) or sham operation. In the probiotic-treated group, BGN4 was administered by gavage once daily, starting 2 weeks before injury. Results: Administration of BGN4 significantly increased gut microbiome diversity and prevented expansion of the Enterobacteriaceae and Bacteroidetes that were the hallmarks of AKI-induced dysbiosis. Further, BGN4 administration also significantly reduced other IRI-induced changes in the colon microenvironment, including effects on permeability, apoptosis of colon epithelial cells, and neutrophil and proinflammatory macrophage infiltration. Mononuclear cells co-cultured with BGN4 expressed significantly increased proportions of CD103<sup>+</sup>/ CD11c<sup>+</sup> and CD4<sup>+</sup> CD25<sup>+</sup> Treg cells, suggesting a direct immunomodulatory effect. BGN4 induced Treg expansion in colon, mesenteric lymph nodes (MNL), and kidney. BGN4 also reduced CX<sub>3</sub>CR<sub>1</sub><sup>intermediate</sup>Ly6C<sup>high</sup> monocyte infiltration and interleukin (IL)-17A suppression in the small intestine, which may have attenuated AKI severity, kidney IL-6 messenger RNA expression, and AKI-induced liver injury. Conclusion: Prior supplementation with BGN4 significantly attenuated the severity of IRI and secondary liver injury. This renoprotective effect was associated with increased Foxp3 and reduced IL-17A expression in the colon, MNL, and kidney, suggesting that BGN4-induced immunomodulation might contribute to its renoprotective effects. Probiotics may therefore be a promising strategy to reduce AKI severity and/or remote organ injury.
( Jihyun Yu ),( Yunmi Shin ),( Dasom Kim ),( Il-hyun Jo ) 한국교육공학회 2017 Educational Technology International Vol.18 No.2
This study attempted to collect learners’ emotion and state motivation, analyze their inner states, and measure state motivation using a non-self-reported survey. Emotions were measured by learning segment in detailed learning situations, and they were used to indicate total state motivation with prediction power. Emotion was also used to explain state motivation by learning segment. The purpose of this study was to overcome the limitations of video-based learning environments by verifying whether the emotions measured during individual learning segments can be used to indicate the learner’s state motivation. Sixty-eight students participated in a 90-minute to measure their emotions and state motivation, and emotions showed a statistically significant relationship between total state motivation and motivation by learning segment. Although this result is not clear because this was an exploratory study, it is meaningful that this study showed the possibility that emotions during different learning segments can indicate state motivation.
최지현 ( Jihyun Choi ),조삼섭 ( Samsup Jo ) 한국PR학회 2017 PR연구 Vol.21 No.1
The purpose of the study was to examine the dimensions of government-public relationship that reflects Korean societal and cultural contexts. This research has an ample significance in reorganizing the Korean organization-public relationship which is the core research topic in the public relations field. In order to achieve the purpose of study, the central government was recognized as a targeting subject organization. Following the conventional measurement development procedure, in-depth review of the literature, pilot survey, and main survey were conducted. Finally, data were analyzed thoroughly according to the common practices to isolate measurement scale. The results showed that Korean government-public relationship contained two dimensions consisting of twelve measurement items. The two construct dimensions were labeled as (a) competency of policy administration; (b) competency of government communication. The results could help Korean government to regain friendly relationship between government and public as well as increase public`s trust toward government.
Yoon, Jihyun,Oh, In-Hwan,Seo, Hyeyoung,Kim, Eun-Jung,Gong, Young-hoon,Ock, Minsu,Lim, Dohee,Lee, Won Kyung,Lee, Ye-Rin,Kim, Dongwoo,Jo, Min-Woo,Park, Hyesook,Yoon, Seok-Jun The Korean Academy of Medical Sciences 2016 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.31 No.suppl2
<P>This study is part of a 5-year research project on the national burden of diseases, injuries, and risk factors in Korea. Using disability-adjusted life years (DALYs), a metric introduced by the 1990 Global Burden of Disease (GBD) project, we performed a comprehensive and detailed assessment of the magnitude and distribution of both fatal and non-fatal health problems in the Korean population. The concept and general approach were consistent with the original GBD study, with some methodological modifications to make the study more suitable for Korea. We computed DALYs for 313 causes in both sexes and nine age groups using the entire population's medical records and newly generated Korean disability weights. In 2012, the dominant disease burden was non-communicable diseases, which accounted for 85.21% of total DALYs, while injuries accounted for 7.77% and communicable, maternal, neonatal, and nutritional disorders for 7.02%. Of the total DALYs, 88.67% were from years lived with disability and 11.32% were from years of life lost due to premature mortality. Diabetes mellitus was the leading cause of DALYs, followed by low back pain, chronic obstructive pulmonary disease, ischemic heart disease, ischemic stroke, cirrhosis of the liver, falls, osteoarthritis, motorized vehicle with three or more wheels, and self-harm. The results reported here identify key health challenges and opportunities for future health interventions and policy changes, and provide information that will help assess the major public health issues in Korea, a nation faced with one of the world's most rapidly ageing populations.</P>
조희영 ( Jo Heeyeong ),김지현 ( Kim Jihyun ) 한국화법학회 2020 화법연구 Vol.0 No.50
The purpose of this study is to categorize the various expressions used in an awards ceremony as part of an “award acceptance speech” to examine their characteristics and establish a pragmatic system of awards impressions. This study revealed the overall characteristics and systems of awards acceptance speeches that were not discussed in the existing literature on speech acts. First, we classified the award acceptance speeches in the speech act and identified the characteristics through the object, purpose, and content. Subsequently, 132 awards acceptance speeches of three broadcasting companies in 2019, Drama Acting Awards, Entertainment Awards, and Blue Dragon Film Awards, were analyzed to identify the actual impressions of Korean speakers’ award acceptance speeches. Through these analyses, the impressions of the award acceptance speech were classified and the pragmatic characteristics of the speeches were summarized.