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Jingjing Lin,Song Yan,Xiaojie Zhang,Yueran Liu,Jun Lian,Hualin Lin,Wei Wei,Deli Lu,Sheng Han 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.4
Holey Fe-Anderson-type polyoxometalate/polyaniline/graphene (PPG) hybrid materials were first prepared by anchoring Anderson-type polyoxometalates [FeMo6O24H6]3- (FeMo6) onto graphene modified with polyaniline via a facile hydrothermal treatment. The as-prepared materials exhibited an excellent electrochemical performance with a high specific capacitance of 1366 F g -1 at 1 A g -1 and outstanding cycling stability (97.6% capacitance retention after 5000 cycle times). The uptake of polyaniline/FeMo6 nanoparticles on graphene not only provided the pseudocapacitance but also weakened the aggregation between the graphene layers, resulting in a higher surface area compared with pure graphene. In addition, the AC//PPG-15 asymmetric supercapacitor device showed a high energy density of 24.65 W h kg -1 at a low power density of 326.25 W kg -1 and good cycling stability (94.82% capacitance retention after 5000 cycles). Hence, the as-prepared PPG hybrid materials in this work possess tremendous potential as electrodes for high-performance supercapacitors.
Yinghao Song,Changxi Li,Jingjing Guan,Cheng Li,Haisheng Wu,Xinzhi Cheng,Bingyu Ling,Jinglang Zhang 대한통증학회 2022 The Korean Journal of Pain Vol.35 No.1
Background: Percutaneous transforaminal endoscopic discectomy (PTED) has been widely used in the treatment of lumbar degenerative diseases. Epidural injection of steroids can reduce the incidence and duration of postoperative pain in a short period of time. Although steroids are widely believed to reduce the effect of surgical trauma, the observation indicators are not uniform, especially the long-term effects, so the problem remains controversial. Therefore, the purpose of this paper was to evaluate the efficacy of epidural steroids following PTED. Methods: We searched PubMed, Embase, and the Cochrane Database from 1980 to June 2021 to identify randomized and non-randomized controlled trials comparing epidural steroids and saline alone following PTED. The primary outcomes included postoperative pain at least 6 months as assessed using a visual analogue scale (VAS) and the Oswestry Disability Index (ODI). The secondary outcomes included length of hospital stay and the time of return to work. Results: A total of 451 patients were included in three randomized and two nonrandomized controlled trials. The primary outcomes, including VAS and ODI scores, did not differ significantly between epidural steroids following PTED and saline alone. There were no significant intergroup differences in length of hospital stay. Epidural steroids were shown to be superior in terms of the time to return to work (P < 0.001). Conclusions: Intraoperative epidural steroids did not provide significant benefits, leg pain control, improvement in ODI scores, and length of stay in the hospital, but it can enable the patient to return to work faster.
The technology and properties of sponge city permeable bricks prepared using refractory waste
Jieguang Song,Xueqing Yang,Ping Chen,Rongjin Liu,Deping Luo,Yuxuan Wei,Wenjin Yao,Jingjing Liu,Qing Zeng 한양대학교 세라믹연구소 2021 Journal of Ceramic Processing Research Vol.22 No.4
With the widespread development of sponge city projects across the country, the use of industrial permeable bricks hasincreased dramatically. My country produces a large amount of refractory waste and pollutes the environment seriously. Wasterefractory insulation bricks are used as the main raw materials, and a small amount of auxiliary raw materials are added toprepare sponge urban permeable bricks through forming and sintering processes. Through performance tests, such asporosity, flexural strength, and water permeability coefficient, the effect of process parameters on the performance ofpermeable bricks is studied, the process parameters of using refractory waste are comprehensively optimized to preparesponge urban permeable bricks, and permeable bricks are prepared for the industrialization of high-quality industrial solidwaste. Brick provides reference. Through the experimental results and analysis, the following conclusions are drawn: the rawmaterial ratio of refractory brick waste: binder: foaming agent: sintering aid is 80:10:1:9. Slurry water mill foaming occurswhen the water to material ratio is 0.5, the ball milling speed is 80 r/min, and the ball milling time is 2 h; the foaming effectand molding performance are better. In the drying stage, drying at 45 oC for 12 h has the best molding effect. The sinteringsystem at 1,300 oC and holding time of 1 h has the best sintering performance. After optimizing the process, the porosity ofthe permeable bricks can reach 48.4%, the water permeability coefficient is 2.1×10^-2 cm/s, the national permeable brick hasA-level standard, and the compressive strength is 26.8 MPa.
Impact of Various Charge States of Hydrogen on Passivation of Dislocation in Silicon
Lihui Song,Jingjing Lou,Jiayi Fu,Zhenguo Ji 대한금속·재료학회 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.5
Dislocation, one of typical crystallographic defects in silicon, is detrimental to the minority carrier lifetime of silicon wafer. Hydrogen passivation is able to reduce the recombination activity of dislocation, however, the passivation efficacy is stronglydependent on the experimental conditions. In this paper, a model based on the theory of hydrogen charge state control isproposed to explain the passivation efficacy of dislocation correlated to the peak temperature of thermal annealing and illuminationintensity. Experimental results support the prediction of the model that a mix of positively charged hydrogen andnegatively charged hydrogen at certain ratio can maximise the passivation efficacy of dislocation, leading to a better powerconversion efficiency of silicon solar cell with dislocation in it.
Diallyl Biphenyl-Type Neolignans Have a Pharmacophore of PPARα/γ Dual Modulators
( Yujia Han ),( Jingjing Liu ),( Sungjin Ahn ),( Seungchan An ),( Hyejin Ko ),( Jeayoung C. Shin ),( Sun Hee Jin ),( Min Won Ki ),( So Hun Lee ),( Kang Hyuk Lee ),( Song Seok Shin ),( Won Jun Choi ),( 한국응용약물학회 2020 Biomolecules & Therapeutics(구 응용약물학회지) Vol.28 No.5
Adiponectin secretion-promoting compounds have therapeutic potentials in human metabolic diseases. Diallyl biphenyl-type neolignan compounds, magnolol, honokiol, and 4-O-methylhonokiol, from a Magnolia officinalis extract were screened as adiponectin- secretion promoting compounds in the adipogenic differentiation model of human bone marrow mesenchymal stem cells (hBM-MSCs). In a target identification study, magnolol, honokiol, and 4-O-methylhonokiol were elucidated as PPARα and PPARγ dual modulators. Diallyl biphenyl-type neolignans affected the transcription of lipid metabolism-associated genes in a different way compared to those of specific PPAR ligands. The diallyl biphenyl-type neolignan structure provides a novel pharmacophore of PPARα/γ dual modulators, which may have unique therapeutic potentials in diverse metabolic diseases.
Synthesis and properties of ultrafine YAG powder via low-temperature microwave hydrothermal method
Yue Liu,Jieguang Song,Lin Chen,Huihui Luo,Guojian Lin,Peng Chen,Chenhui Wei,Jingjing Liu 한양대학교 세라믹연구소 2020 Journal of Ceramic Processing Research Vol.21 No.4
Yttrium aluminum garnet (YAG) has good optical properties and has been widely used in engineering. The preparation ofconventional YAG powder is costly due to its high synthesis temperature, so lowering the synthesis temperature is the mosteffective way to save cost. The ultrafine oxide composite powder was rapidly synthesized using the microwave hydrothermalmethod at a low temperature. The effect of temperature and its performance. Differential thermal analysis and XRD phaseanalysis showed the mixed solution of Al(NO3)3 and Y(NO3)3 at pH=9 and C(Al3+)=0.42 mol·L−1. SEM, zeta potential, andparticle size analysis revealed that the microwave hydrothermal reaction temperature was 170 oC, and the high-purityultrafine YAG powder was calcined at 928 oC, which was lower than conventional calcination temperature. The synthesizedultrafine spherical YAG powder had a small particle size and a uniform distribution.
Volume Compatibility of Interlayer Treatment Materials with Roller-Compacted Concrete
Xiaoliang Zhu,Yuxin Gao,Wenjing Song,Jingjing Xu,Chengyang Li,Zhaoheng Guo,Fang Chen,Rui Zhang 대한토목학회 2022 KSCE Journal of Civil Engineering Vol.26 No.3
Interlayer is the weakest plane of the entire roller-compacted concrete (RCC) structure and is easily deteriorated under the pressure of water and other environmental factors. Shearing force induced by the different shrinkage in interlayer part is the main reason for that poor performance of the RCC. In this paper, the deformation of RCC concrete and interlayer treatment mortar with supplementary cementitious materials (SCMs, including fly ash and silica fume) and double expansive resources admixtures (HME, containing calcium sulphoaluminate (CSA) and CaO) were studied. Deformation of concrete (produced RCC) and interlayer treatment materials was modeled and compared. Porosity characters of interlayer treatment materials and water absorption of interlayer-treated RCC samples were tested. Results showed that the HME significantly reduced the shrinkage of mortar and the deformation difference degree between layers was shortened. Modified interlayer treatment materials with HME could modify the macroscopic properties of RCC, the low porosity of interlayer and water absorption of interlayer-treated RCC was resulted. The suitable HME content is necessary in interlayer treatment materials and which could improve the performance of RCC.
MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis
Yang Yang,Rongfang Qiu,Qiaoyou Weng,Ziwei Xu,Jingjing Song,Siyu Zhao,Miaomiao Meng,Dengke Zhang,Chunli Kong,Hailin Wang,Min Xu,Zhongwei Zhao,Jiansong Ji 대한암학회 2023 Cancer Research and Treatment Vol.55 No.3
Purpose Mixed-lineage leukemia protein 4 (MLL4/KMT2D) is a histone methyltransferase, and its mutation has been reported to be associated with a poor prognosis in many cancers, including lung cancer. We investigated the function of MLL4 in lung carcinogenesis. Materials and Methods RNA sequencing (RNA-seq) in A549 cells transfected with control siRNA or MLL4 siRNA was performed. Also, we used EdU incorporation assay, colony formation assays, growth curve analysis, transwell invasion assays, immunohistochemical staining, and in vivo bioluminescence assay to investigate the function of MLL4 in lung carcinogenesis. Results We found that MLL4 expression was downregulated in non–small cell lung cancer (NSCLC) tissues compared to adjacent normal tissues and tended to decrease with disease stage progression. We analyzed the transcriptomes in control and MLL4- deficient cells using high-throughput RNA deep sequencing (RNA-seq) and identified a cohort of target genes, such as SOX2, ATF1, FOXP4, PIK3IP1, SIRT4, TENT5B, and LFNG, some of which are related to proliferation and metastasis. Our results showed that low expression of MLL4 promotes NSCLC cell proliferation and metastasis and is required for the maintenance of NSCLC stem cell properties. Conclusion Our findings identify an important role of MLL4 in lung carcinogenesis through transcriptional regulation of PIK3IP1, affecting the PI3K/AKT/SOX2 axis, and suggest that MLL4 could be a potential prognostic indicator and target for NSCLC therapy.