한국인 정상교합자의 3차원 디지털 모형을 이용한 순,협측 치면 곡률

채지현,송진욱,차정열,최정수,박영철 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.2

본 연구는 한국인의 치아형태에 적합한 브라켓 베이스를 만들기 위해 임상 치관의 순, 협측 곡률을 3차원적으로 계측하여 치관의 곡률 자료를 얻고자 하였다. 정상적인 해부학적 형태를 가지는 구강모형 30쌍을 3차원 디지털 모델로 제작한 후, FA점을 기준으로 수평 기준면과 수직 기준면을 설정하였다. 이 기준면에 대한 치면의 곡선을 형성한 후, 곡률을 이차방정식의 계수로 표현하였다. 수평면과 수직면의 곡률과 FA점을 기준으로 근심과 원심, 치은측과 교합면측의 곡률을 측정한 결과, 상악견치와 상악 제2소구치 외에는 남녀간 치면 곡률의 유의한 차이가 없었다. 하악 측절치, 상악 견치, 상하악 제1, 2소구치와 제1대구치에서 근원심 또는 치은교합면측 치면 곡률의 유의한 차이가 관찰되었다 (P < 0.05). 본 연구에서 얻어진 순, 협측 치면의 곡률 자료는 한국인의 치아 형태에 적합한 Straight Wire Appliance 개발의 기초 자료로 활용될 수 있다. Objective: This study was performed to investigate the labio/buccal clinical crown curvatures of Korean permanent teeth and to obtain the curve-ratio data in an attempt to fabricate bracket bases fit for each individual Korean permanent tooth. Methods: Three-dimensional digital models were made from 30 sets of dental casts with normal anatomic structures. According to the FA points, horizontal and vertical reference planes were established and lines were drawn on the tooth surfaces in reference to these planes. The curvature was expressed as the coefficient of a quadratic equation. Lines mesial, distal, gingival and occlusal to the horizontal, vertical reference planes and the FA point were drawn. Results: The curvature measured for each line revealed that there are no significant differences between male and female, except for maxillary canines and maxillary second bicuspids (P > 0.05). There were notable differences in the mesio-distal or gingivo-occlusal curvatures among the mandibular lateral incisors, maxillary canines, maxillary and mandibular first and second bicuspids and first molars (P < 0.05). Conclusions: The labial & buccal crown curvatures of teeth in Korean normal occlusion were measured on the mesial and distal, gingival and occlusal sides respectively in this study. Based on these data, a SWA can be developed to fit the individual features of Korean tooth crowns.

Skeletal and dentoalveolar changes after miniscrewassisted rapid palatal expansion in young adults

Jung Jin Park,Young-Chel Park,Kee-Joon Lee,Jung-Yul Cha,Ji Hyun Tahk,Yoon Jeong Choi 대한치과교정학회 2017 대한치과교정학회지 Vol.47 No.2

Objective: The aim of this study was to evaluate the skeletal and dentoalveolar changes after miniscrew-assisted rapid palatal expansion (MARPE) in young adults by cone-beam computed tomography (CBCT). Methods: This retrospective study included 14 patients (mean age, 20.1 years; range, 16–26 years) with maxillary transverse deficiency treated with MARPE. Skeletal and dentoalveolar changes were evaluated using CBCT images acquired before and after expansion. Statistical analyses were performed using paired t -test or Wilcoxon signed-rank test according to normality of the data. Results: The midpalatal suture was separated, and the maxilla exhibited statistically significant lateral movement (p < 0.05) after MARPE. Some of the landmarks had shifted forwards or upwards by a clinically irrelevant distance of less than 1 mm. The amount of expansion decreased in the superior direction, with values of 5.5, 3.2, 2.0, and 0.8 mm at the crown, cementoenamel junction, maxillary basal bone, and zygomatic arch levels, respectively (p < 0.05). The buccal bone thickness and height of the alveolar crest had decreased by 0.6–1.1 mm and 1.7–2.2 mm, respectively, with the premolars and molars exhibiting buccal tipping of 1.1o–2.9o. Conclusions: Our results indicate that MARPE is an effective method for the correction of maxillary transverse deficiency without surgery in young adults.

Rapid Origin Determination of the Northern Mauxia Shrimp (Acetes chinensis) Based on Allele Specific Polymerase Chain Reaction of Partial Mitochondrial 16S rRNA Gene

Kang, Jung-Ha,Noh, Eun-Soo,Park, Jung-Youn,An, Chel-Min,Choi, Jung-Hwa,Kim, Jin-Koo Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.4

Acetes chinensis is an economically important shrimp that belongs to the Sergestidae family; following fermentation, A. chinensis' economic value, however, is low in China, and much of the catch in China is exported to Korea at a low price, thus leading to potential false labeling. For this reason, we developed a simple method to identify A. chinensis' origin using allele-specific polymerase chain reaction (PCR). Ten single nucleotide polymorphisms (SNPs) were identified from partial (i.e., 570 bp) DNA sequence analysis of the mitochondrial 16s rRNA gene in 96 Korean and 96 Chinese individual shrimp. Among 10 SNP sites, four sites were observed in populations from both countries, and two sites located in the middle with SNP sites at their 3'-ends were used to design allele-specific primers. Among the eight internal primers, the C220F primer specific to the Chinese A. chinensis population amplified a DNA fragment of 364 bp only from that population. We were able to identify the A. chinensis population origin with 100% accuracy using multiplex PCR performed with two external primers and C220F primers. These results show that the 16S rRNA gene that is generally used for the identification of species can be used for the identification of the origin within species of A. chinensis, which is an important finding for the fair trade of the species between Korea and China.

CMCIS 시스템 개발을 위한 국내외 동향 분석

정현철(Hyon-Chel Jung),김태군(Tea-Koon Kim),김진문(Jin-Mun Kim),유재영(Jae-Young Yoo),진호(Ho Jin),김홍삼(Hong-Sam Kim),박명철(Myeong-Chul Park),전재훈(Jea-Hoon Jun) 한국컴퓨터정보학회 2016 한국컴퓨터정보학회 학술발표논문집 Vol.24 No.1

본 연구에서는 표준 게이트웨이 기반의 다중 생체계측 장비 및 CMCIS(Central Monitoring and Cardiology Information System) 기반의 통합 시스템을 개발하기 위한 타당성 분석을 위한 국내외 동향을 분석한 연구이다. 개발의 필요성을 타진하기 위하여 기술, 사회, 경제적 중요성과 국내외 관련기술의 현황을 분석하였다. 분석한 결과, 대부분 해외의 다국적 기업에 의존하는 실정이며 심혈관계 질환의 지속적 증가로 효율적인 의료 서비스를 위한 기술개발의 필요성이 높게 평가되었다. 또한 표준 게이트웨이 기술의 확보로 진단용 심전계 표준 게이트웨이를 적용함으로써 다양한 HIS 인터페이스가 가능하며, 편의성이 증대되어 활용성이 높아질 것으로 예상된다.

Prognostic Value of Pre-Treatment SCC-Ag Level in Patients with Cervical Cancer

( Jung Joo An ),( Yoo Young Lee ),( Jin Young Park ),( Chel Hun Choi ),( Tae Joong Kim ),( Jeong Won Lee ),( Byoung Gie Kim ),( Duk Soo Bae ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.8

The purpose of this study is to investigate the prognostic role of pre-treatment squamous cell carcinoma-related antigen (SCC-Ag) level in patients with squamous cell carcinoma of the uterine cervix. Methods In this study, we retrospectively enrolled patients with squamous cell carcinoma of the uterine cervix (FIGO stage IB to IVA) who were treated at Samsung Medical Center, Seoul, Korea, from 1996 to 2007. Results We retrospectively enrolled 788 patients. Median SCC-Ag level was 1.6 ng/mL (reference range, 0.1-362.0) in all patients. Four hundred seven out of 788 patients had elevating pre-treatment SCC-Ag level (51.6%). When we divided the cohort based on the stage (early cervical carcinoma; IB1 and IIA vs. locally advanced cervical carcinoma [LACC]; IB2 and IIB to IVA) and performed multivariate analysis, pre-treatment SCC-Ag entailed prognostic significance only in LACC (progression-free survival: hazard ratio [HR], 1.007; 95% confidential interval [CI], 1.003-1.010; overall survival: HR, 1.005; 95% CI, 1.001-1.009). Among patients who showed recurrence disease and had the result of SCC-Ag before recurrence (n=94), 79 patients (84.0%) had the elevation of SCC-Ag level at the time of recurrence. Conclusion Pre-treatment SCC-Ag level is an independent prognostic factor for survival in patients with LACC. Measuring pre-treatment serum SCC-Ag may be a cost-effective method to predict prognosis in patients with LACC.

Subsethood Measure and Entropy of Interval-valued Intuitionistic Fuzzy Sets

Jin Han Park,Ki Moon Lim,Young Chel Kwun,Mi Jung Son 한국지능시스템학회 2007 한국지능시스템학회 학술발표 논문집 Vol.17 No.2

A Generalized Intuitionistic Fuzzy Soft Set Theoretic Approach to Decision Making Problems

Jin Han Park,Young Chel Kwun,Mi Jung Son 한국지능시스템학회 2011 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.11 No.2

The problem of decision making under imprecise environments are widely spread in real life decision situations. We present a method of object recognition from imprecise multi observer data, which extends the work of Roy and Maji [J. Compu. Appl. Math. 203(2007) 412-418] to generalized intuitionistic fuzzy soft set theory. The method involves the construction of a comparison table from a generalized intuitionistic fuzzy soft set in a parametric sense for decision making.

Multi-person Multi-attribute Decision Making Problems Based on Interval-valued Intuitionistic Fuzzy Information

Jin Han Park,Young Chel Kwun,Mi Jung Son 한국지능시스템학회 2010 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.10 No.4

Based on the interval-valued intuitionistic fuzzy hybrid geometric (IIFHG) operator and the interval-valued intuitionistic fuzzy weighted geometric (IIFWG) operator, we investigate the group decision making problems in which all the information provided by the decision-makers is presented as interval-valued intuitionistic fuzzy decision matrices where each of the elements is characterized by interval-valued intuitionistic fuzzy numbers, and the information about attribute weights is partially known. A numerical example is used to illustrate the applicability of the proposed approach.

Metabolic phenotyping of human atherosclerotic plaques: Metabolic alterations and their biological relevance in plaque-containing aorta

Jung, Sunhee,Song, Suk-Won,Lee, Sak,Kim, Se Hoon,Ann, Soo-jin,Cheon, Eun Jeong,Yi, Gijong,Choi, Eui-Young,Lee, Seung Hyun,Joo, Hyun-Chel,Ryu, Do Hyun,Lee, Sang-Hak,Hwang, Geum-Sook Elsevier 2018 Atherosclerosis Vol.269 No.-

<P><B>Abstract</B></P> <P><B>Background and aims</B></P> <P>Atherosclerosis is a chronic inflammatory disease characterized by thickening of the arterial wall. However, a limited number of studies have been conducted on metabolic profiling of human aortic tissue.</P> <P><B>Methods</B></P> <P>We applied liquid chromatography/mass spectrometry to perform global and targeted profiling of plaque-containing aortic tissue. The aorta samples included plaque-containing (n = 18) and control plaque-free (n = 24) aortic tissue from patients undergoing aortic surgery.</P> <P><B>Results</B></P> <P>The metabolic patterns of atherosclerotic and control vessels were significantly different. Metabolites in the purine and glutathione pathways showed dysregulation of oxidative stress in plaques, and levels of glucosylceramide, tryptophan, and kynurenine, which are related to inflammation, were also altered. Interestingly, an increased level of quinic acid was observed in plaques (<I>p</I> < 0.000), and we demonstrated an inhibitory effect of quinic acid on inflammatory activation and oxidative stress in macrophages.</P> <P><B>Conclusions</B></P> <P>Our study provides insight into the disease mechanism and potential markers of atherosclerosis through comprehensive metabolic profiling of human aortic tissue samples containing plaque.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Metabolic profiling in plaque-containing and plaque-free aortic tissue was applied. </LI> <LI> The metabolic patterns of atherosclerotic and control vessels were significantly different. </LI> <LI> Metabolites related to oxidative stress and inflammation were altered in atherosclerotic aorta. </LI> <LI> Quinic acid level in plaques was increased and its biological effects were demonstrated. </LI> <LI> Metabolic profiling provides an overview of the metabolic dysregulation in atherosclerotic aorta. </LI> </UL> </P>

Primary ovarian choriocarcinoma mimicking ectopic pregnancy

( Eun Jin Heo ),( Chel Hun Choi ),( Jung Min Park ),( Jeong Won Lee ),( Duk Soo Bae ),( Byoung Gie Kim ) 대한산부인과학회 2014 Obstetrics & Gynecology Science Vol.57 No.4

Nongestational ovarian choriocarcinoma is an exceedingly rare and highly aggressive tumor. Although early diagnosis and timely initiation of therapy is important, it is difficult in reproductive aged patients because of the frequent elevation of human chorionic gonadotropin. We report a primarily nongestational ovarian choriocarcinoma in a 12-year-old virgin female. Initial diagnosis based on abdominopelvic computed tomography and pelvis magnetic resonance imaging was ectopic pregnancy with hemoperitoneum. A diagnostic laparoscopy of the ovarian tumor revealed choriocarcinoma. Unilateral salpingo-oophorectomy and omental sampling revealed surgical stage of IA. Six courses of adjuvant combination chemotherapy (bleomycin, etoposide, and cisplatin) followed surgery.