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      • SCOPUS

        Highly Porous Silica Nanoaerogels for Ultrafast Nonlinear Optical Applications

        Seo, Jae Tae,Ma, S.M.,Lee, K.,Brown, H.,Jackson, A.,Skyles, T.,Cubbage, N.M.,Tabibi, B.,Yoo, K.P.,Kim, Suk Young,Jung, S.S.,Namkung, M. Trans Tech Publications, Ltd. 2005 Key Engineering Materials Vol.287 No.-

        <P>Highly porous silica nanoaerogels with low apparent density of ~0.1 g/cm3 and ~0.07 g/cm3 were synthesized through two-step sol-gel processing and low temperature supercritical fluid drying. The nonlinear refraction (γ) of silica nanoaerogels was estimated to be ~ -3.4 x 10-16 m2/W for ~0.1 g/cm3 and ~0.07 g/cm3 apparent densities with a signal-beam femtosecond z-scan spectroscopy. The third-order nonlinear refraction coefficient of nanostructure silica nanoaerogels was almost four orders larger than that of bulk silica materials. The large nonlinearrefraction with high nonlinear figure of merit (γ/βλ, β~2×10-10 m/W for 0.07 g/cm3 apparent density, β~6×10-10 m/W for 0.1 g/cm3 apparent density, λ~0.775 µm) is an ideal optical property for nonlinear applications of homeland security, battlefield enhancement, and industrial uses.</P>

      • KCI등재

        RANGE EXTENDER MODULE TRANSMISSION TOPOLOGY STUDY

        Konrad Herold,Marius Böhmer,Rene Savelsberg,Alexander Müller,Jan Schröter,Jan Karthaus,Un-Jae Seo,Georg Jacbos,Kay Hameyer,Jakob Andert 한국자동차공학회 2018 International journal of automotive technology Vol.19 No.5

        Range extender modules are one option to compensate for short drive ranges of electric vehicles. The close interaction of combustion engine and generator poses new challenges in development. A key requirement for range extender systems is to be light and virtually imperceptible in operation. High-speed electrical machines aim at increasing power density. However, their introduction in a range extender requires a gearbox. The combustion engine torque fluctuations can lead to rattle in the gearbox. The rattle can be overcome by a dual mass flywheel. An interdisciplinary model is developed and used to analyse three different range extender systems: one with a low speed generator without gearbox, one with a high-speed generator, and one with a high-speed generator and a dual mass flywheel. The efficiency was found to be higher for the system with a low speed generator, whereas the power density and the costs are beneficial for the high-speed concept. A dual mass flywheel eliminates the changes of torque direction in the gearbox. It reduces the speed fluctuations of the gearbox and generator by over 90 % compared to the low speed setup. But it increases rolling moment and subsequently chassis excitation compared to a setup with only a gearbox.

      • IRAS 15099-5856: REMARKABLE MID-INFRARED SOURCE WITH PROMINENT CRYSTALLINE SILICATE EMISSION EMBEDDED IN THE SUPERNOVA REMNANT MSH15-5<i>2</i>

        Koo, Bon-Chul,McKee, Christopher F.,Suh, Kyung-Won,Moon, Dae-Sik,Onaka, Takashi,Burton, Michael G.,Hiramatsu, Masaaki,Bessell, Michael S.,Gaensler, B. M.,Kim, Hyun-Jeong,Lee, Jae-Joon,Jeong, Woong-Seo IOP Publishing 2011 The Astrophysical journal Vol.732 No.1

        <P>We report new mid-infrared (MIR) observations of the remarkable object IRAS 15099-5856 using the space telescopes AKARI and Spitzer, which demonstrate the presence of prominent crystalline silicate emission in this bright source. IRAS 15099-5856 has a complex morphology with a bright central compact source (IRS1) surrounded by knots, spurs, and several extended (similar to 4') arc-like filaments. The source is seen only at >= 10 mu m. The Spitzer mid-infrared spectrum of IRS1 shows prominent emission features from Mg-rich crystalline silicates, strong [Ne II] 12.81 mu m, and several other faint ionic lines. We model the MIR spectrum as thermal emission from dust and compare with the Herbig Be star HD 100546 and the luminous blue variable R71, which show very similar MIR spectra. Molecular line observations reveal two molecular clouds around the source, but no associated dense molecular cores. We suggest that IRS1 is heated by UV radiation from the adjacent O star Muzzio 10 and that its crystalline silicates most likely originated in a mass outflow from the progenitor of the supernova remnant (SNR) MSH 15-52. IRS1, which is embedded in the SNR, could have been shielded from the SN blast wave if the progenitor was in a close binary system with Muzzio 10. If MSH 15-52 is a remnant of Type Ib/c supernova (SN Ib/c), as has been previously proposed, this would confirm the binary model for SN Ib/c. IRS1 and the associated structures may be the relics of massive star death, as shaped by the supernova explosion, the pulsar wind, and the intense ionizing radiation of the embedded O star.</P>

      • KCI등재후보

        Tc-99m Sestamibi Scintigraphy를 이용한 부갑상선과 갑상선 결절의 감별진단

        서승원<SUP>1<,SUP>,주재균<SUP>1<,SUP>,윤정한<SUP>1<,SUP>,제갈영종<SUP>1<,SUP>,범희승<SUP>2<,SUP>,Seung Won Seo,M,D,<SUP>1<,SUP>,Jae Kyun Joo,M,D,<SUP>1<,SUP>,Jung Han Yoon,M,D,<SUP>1<,SUP>,Young Jong Jaegal,M,D,<SUP> 대한갑상선-내분비외과학회 2002 The Koreran journal of Endocrine Surgery Vol.2 No.1

        Purpose: Differentiation of parathyroid and thyroid nodule is often difficult even with aids of ultrasonography and computed tomography. Tc-9m sestamibi (MIBI) scintigraphy is useful in the detection of hyperfuntioning parathyroid nodules. However, its role in the differentiation between parathyroid and thyroid nodules including malignancies is not well studied. Therefore, the purpose of this study is to evlauate the role of Tc-99m MIBI imaing in the differentiation of parathyroid adenoma from thyroid malignancy. Methods: Six patients (4 women, 2 men, mean age 43 years) with parathyroid adenoma and 4 patients (2 women, 2 men, mean age 56 years) with thyroid papillary cancer were enrolled. Ten and 180 minutes after injection of 740 MBq Tc-99m MIBI, pinhole image of the anterior neck was obtained. Nodule-to-thyroid ratio (N:T) was measured from same sized region of interests over nodule and normal thyroid bed. Retention Index (RI) was calculated as N:T 10 minus N:T 180 divided by N:T 10. Results: Patients with parathyroid adenoma showed similar N:T 10 as those with thyroid cancer (1.09 ⁢/⁣ 0.35, 1.24⁢/⁣ 0.36, respectively, P>0.05 ). However, RI of parathyroid patients was higher than thyroid cancer patients (0.64 ⁢/⁣ 0.29, ⁣0.12⁢/⁣ 0.20, respectively, P<0.05). Conclusion: Parathyroid adenoma showed higher retention rate of Tc-99m MIBI than thyroid cancer. Therefore, differntiation of parathyroid and thyroid nodule could be possible using Tc-99m MIBI scintigraphy. (Korean J Endocrine Surg 2002;2:15-18)

      • Large-Area Fabrication of Patterned ZnO-Nanowire Arrays Using Light Stamping Lithography

        Hwang, Jae K.,Cho, Sangho,Seo, Eun K.,Myoung, Jae M.,Sung, Myung M. American Chemical Society 2009 ACS APPLIED MATERIALS & INTERFACES Vol.1 No.12

        <P>We demonstrate selective adsorption and alignment of ZnO nanowires on patterned poly(dimethylsiloxane) (PDMS) thin layers with (aminopropyl)siloxane self-assembled monolayers (SAMs). Light stamping lithography (LSL) was used to prepare patterned PDMS thin layers as neutral passivation regions on Si substrates. (3-Aminopropyl)triethoxysilane-based SAMs were selectively formed only on regions exposing the silanol groups of the Si substrates. The patterned positively charged amino groups define and direct the selective adsorption of ZnO nanowires with negative surface charges in the protic solvent. This procedure can be adopted in automated printing machines that generate patterned ZnO-nanowire arrays on large-area substrates. To demonstrate its usefulness, the LSL method was applied to prepare ZnO-nanowire transistor arrays on 4-in. Si wafers.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2009/aamick.2009.1.issue-12/am900580v/production/images/medium/am-2009-00580v_0007.gif'></P>

      • KCI등재

        Clinical Utility of Quantitative CT Analysis for Fissure Completeness in Bronchoscopic Lung Volume Reduction: Comparison between CT and Chartis™

        Sei Won Lee, M.D., Ph.D,So Youn Shin,Tai Sun Park,Yoon Young Choi,Jong Chun Park,Jina Park,오상영,Namkug Kim,Se Hee Lee,Jae Seung Lee, M.D,Joon Beom Seo,오연목,Sang-Do Lee, M.D., Ph.D.,이상민 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.7

        Objective: The absence of collateral ventilation (CV) is crucial for effective bronchoscopic lung volume reduction (BLVR) with an endobronchial valve. Here, we assessed whether CT can predict the ChartisTM results. Materials and Methods: This study included 69 patients (mean age: 70.9 ± 6.6 years; 66 [95.7%] males) who had undergone CT to assess BLVR eligibility. The ChartisTM system (Pulmonox Inc.) was used to check CV. Experienced thoracic radiologists independently determined the completeness of fissures on volumetric CT images. Results: The comparison between the visual and quantitative analyses revealed that 5% defect criterion showed good agreement. The ChartisTM assessment was performed for 129 lobes; 11 (19.6%) of 56 lobes with complete fissures on CT showed positive CV, while this rate was significantly higher (40 of 49 lobes, i.e., 81.6%) for lobes with incomplete fissures. The size of the fissure defect did not affect the rate of CV. Of the patients who underwent BLVR, 22 of 24 patients (91.7%) with complete fissures and three of four patients with incomplete fissures (75%) achieved target lobe volume reduction (TLVR). Conclusion: The quantitative analysis of fissure shows that incomplete fissures increased the probability of CV on ChartisTM, while the defect size did not affect the overall rates. TLVR could be achieved even in some patients with relatively large fissure defect, if they showed negative CV on ChartisTM.

      • KCI등재후보

        갑상선 미세유두상암의 임상적 특성

        안재현,최재영<SUP>1<.SUP>,박원서,송정윤,김용호,이상목,고석환,Jae Hyun Ahn,M.D.,Jae Young Choi,M.D.<SUP>1<.SUP>,Won Seo Park,M.D.,Jeong Yoon Song,M.D.,Yong Ho Kim,M.D.,Sang Mok Lee,M.D. and Suck Hwan Koh,M.D. 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.2

        <B>Purpose:</B> PTMC is defined as a papillary thyroid cancer smaller than 10 mm in its greatest diameter. It is the most common form of differentiated thyroid cancer and its prognosis is known to be very favorable. The aim of this study is to identify its biologic behavior and to formulate a reasonable therapeutic strategy for the treatment of PTMC. <B>Methods:</B> 379 patients with papillary thyroid cancer were analyzed. Each patient was diagnosed preoperatively or postoperatively and treated between Jan. 2000 and Dec. 2007. Among these patients, 143 had been identified as having PTMC (37.7%) with a mean tumor size of 0.72 cm in diameter. <B>Results:</B> There were no significant differences of the clinical characteristics such as gender, age, the operative methods, or multicentricity between the PTMC group and the non-PTMC group, except for LN metastases. Also, there were fewer symptoms of palpable neck mass and preoperative findings such as capsular invasion and microcalcification in the PTMC group. We performed unilateral lobectomy with or without central compartment neck node dissection for the early stage diseases, but for the later stages of disease we performed near-total or total thyroidectomy with routine central compartment neck node dissection. And for the patients with lateral node enlargement, we performed ipsilateral modified radical neck dissection (MRND). <B>Conclusion:</B> This study shows that PTMC is quite similar to conventional papillary thyroid cancer in its biological behavior, and we conclude that total thyroidectomy with central compartment neck node dissection is the proper therapeutic strategy to treat PTMC. However, further study is necessary for identifying the low-risk and high-risk patients with PTMC. <B>(Ko</B><B></B><B>rean J Endocrine Surg 2008;8:101-105)</B>

      • KCI등재후보

        수술자가 시행하는 수술 전 갑상선 초음파 검사의 유용성

        장재훈,최재영<SUP>1<.SUP>,박원서,송정윤,고석환,Jae Hoon Jang,M.D.,Jae Young Choi,M.D.,Ph.D.<SUP>1<.SUP>,Won Seo Park,M.D.,Jeong Yoon Song,M.D.,Ph.D. and Suck Hwan Koh,M.D.,Ph.D. 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.1

        <B>Purpose: </B>Although the diagnostic accuracy of thyroid cancer by fine needle aspiration cytology (FNAC) is increasing, there are some nodules for which ultrasonography and FNAC show indeterminant. The purpose of this study was to determine the usefulness of thyroid ultrasonography by the surgeon prior to operation <B>Methods:</B> Forty-nine patients who underwent thyroid operations between June 2006 and January 2007 were selected for this study. Thyroid ultrasonography was performed on each patient.And we recorded and analyzed the shape and the margin of the nodule, internal echogeneiety, heterogeneiety, the presence of microcalcification, height versus width, and the presence of level VI lymph node larger than 3 mm, assigning each a score of 1, 2 or 3. <B>Results: </B>The average score was 17.1. Assuming an average score over 14 is considered to be malignant, the sensitivity, specificity, positive predictive value, and negative predictive value were 95.6%, 88.9%, 91.7%, 94.1% respec</B>tively. Statistically significant characteristics of malignancy were the shape and the margin of the nodule, internal echogeneiety, microcalcification, taller than wide shape and the presence of enlarged VI lymph nodes. The heterogeneiety had no significant P value. <B>Conclusion: </B>When malignancy cannot be confirmed even after repeated FNAC, preoperative ultrasonograpy performed by surgeons can be a reliable test and helpful for operations. <B>(Ko</B><B>rean J Endocrine Surg 2008;8:28-32)</B>

      • Comparative Assessment of Parametric Neuroreceptor Mapping Approaches Based on the Simplified Reference Tissue Model Using [<sup>11</sup>C]ABP688 PET

        Seo, Seongho,Kim, Su J,Kim, Yu K,Lee, Jee-Young,Jeong, Jae M,Lee, Dong S,Lee, Jae S SAGE Publications 2015 Journal of cerebral blood flow and metabolism Vol.35 No.12

        <P> In recent years, several linearized model approaches for fast and reliable parametric neuroreceptor mapping based on dynamic nuclear imaging have been developed from the simplified reference tissue model (SRTM) equation. All the methods share the basic SRTM assumptions, but use different schemes to alleviate the effect of noise in dynamic-image voxels. Thus, this study aimed to compare those approaches in terms of their performance in parametric image generation. We used the basis function method and MRTM2 (multilinear reference tissue model with two parameters), which require a division process to obtain the distribution volume ratio (DVR). In addition, a linear model with the DVR as a model parameter (multilinear SRTM) was used in two forms: one based on linear least squares and the other based on extension of total least squares (TLS). Assessment using simulated and actual dynamic [<SUP>11</SUP>C]ABP688 positron emission tomography data revealed their equivalence with the SRTM, except for different noise susceptibilities. In the DVR image production, the two multilinear SRTM approaches achieved better image quality and regional compatibility with the SRTM than the others, with slightly better performance in the TLS-based method. </P>

      • SCISCIESCOPUS

        Hierarchical and Multifunctional Three‐Dimensional Network of Carbon Nanotubes for Microfluidic Applications

        Seo, Jeongeun,Lee, Tae Jae,Ko, Seungbin,Yeo, Haegu,Kim, Suhawn,Noh, Taeyong,Song, Simon,Sung, Myung M.,Lee, Haiwon WILEY‐VCH Verlag 2012 Advanced Materials Vol.24 No.15

        <P><B>Three‐Dimensional network of carbon nanotubes:</B> The 3D network of CNTs have hierarchical structures comprised of interconnected SWNTs between Si pillars in microfluidic channels. The Al<SUB>2</SUB>O<SUB>3</SUB> coated 3D networks were used for size different nanoparticles filtration and streptavidin capturing in very diluted solution. The 3D network of SWNTs systems will provide a robust multifuncitonal platform for a variety of biomedical and environmental applications.</P>

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