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Development of machine learning-based early warning system
( Bo-gun Kho ),( In-jae Oh ),( Min-seok Kim ),( Tae-ok Kim ),( Cheol-kyu Park ),( Young-chul Kim ),( Soon Whan Kang ),( Jae Hoon Jung ),( Sung Hoon Baek ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
A rapid response system is a patient safety system that prevents unexpected mortality by providing immediate interventions. But there are also difficulties in costs and human resources for implementation. Machine learning is an application of artificial intelligence that provides systems the ability to automatically learn and improve from experience without being explicitly programmed. We try to develop an early warning system to predict intubation and cardiopulmonary resuscitation using machine learning. The training set was composed of all patients admitted to Chonnam National University Hwasun Hospital for two years (event group 277 vs. non-event group 3576 cases), and the test set was made from all patients admitted to Chonnam National University Hospital for four months (event group 61 vs. non-event group 2334 cases). The algorithm is developed using blood pressure, heart rate, body temperature, respiratory rate, and oxygen saturation. We compared the ensemble model with recurrent neural network (RNN), random forest, logistic regression, and modified early warning score (MEWS) using receiver operating characteristic area under curve (ROC AUC) and precision recall AUC (PR AUC) analyses. The ROC AUC value of the ensemble model was 0.9219 and the PR AUC was 0.0732. This values showed higher tendency than those of other models (RNN: 0.8806 and 0.0732, random forest: 0.9125 and 0.0566, logistic regression: 0.8734 and 0.0513, MEWS: 0.7253 and 0.0468). And the score of the event group rose above the threshold 36 hours before events in the ensemble model. Development of machine learning-based early warning system is feasible because the ensemble model showed high ROC AUC value than traditional models. However, the low PR AUC value suggests that more efforts are needed to use in practice.
Kho Sam il,Kim Min Su,Sohn Sun Young,Jung Dong Geun,Boo Jin Hyo,Jeong Seong Hoon,Park SangHee Ko The Korean Vacuum Society 2005 Applied Science and Convergence Technology Vol.14 No.4
For the longevity of OLEDs, passivation of OLEDs is an important process step since organic materials used in OLEDs are very vulnerable to moisture. In this work, the passivation effect of the plasma polymerized para-xylene (PP$\rho$X) layers was studied. The PPpX layers deposited by PECVD were formed on top of the cathode with various plasma powers of 50 - 90 W. Passivation effect of PP$\rho$X was significantly dependent upon the deposition plasma power of the PP$\rho$X film. The lifetime of OLEDs with the 70 W deposited PP$\rho$X passivation layer was about 5 times longer than that of the control device.
직접 적응 제어 기법을 이용한 혼돈 비선형 시스템의 신경 회로망 제어기 설계
고재원,박진배,주진만,오기훈,박광성 연세대학교 산업기술연구소 1996 논문집 Vol.28 No.2
This paper presented a design method of the neural network controller based on the direct adaptive control method, which has an advantage that the additional system identification is not necessary, for the intelligent control of chaotic nonlinear systems. In order to evaluate the performance of our proposed neural network controller, we applied it to the Duffing equation and the Lorenz equation and compares our controller with other neural network controllers through computer simulations. The simulation results show the effectiveness of our controller.
고인관,김남규,백광흠,신형식,김재민,김영수,고용,오성훈,오석전,김광명 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.2
Spontaneous epidural hematoma in the spinal canal is an uncommon entity and has usually caused progressive neurological deficits and surgical decompression should be required. A 27-year-old patient suffered from acutely developed back pain, associated with a wrenching movement of the back. Several hours later, the symptoms were exaggerated with severely radiating pain to the posterior thigh and calf. The diagnosis was made on CT scan. The patient's clinical manifestations improved completely over a few days with surgical intervention. We reviewed the literatures and discussed the etiological factors of spinal epidural hematoma and the utility of CT scan in differentiating other cause of back pain.
高炳勳,金聖子 고려대학교 의과대학 1977 고려대 의대 잡지 Vol.14 No.3
This study focusing on family planning, induced abortion, delivery milieu including prenatal care, places of delivery, attendants at delivery and tools used to cut umbilical cord, and registration of birth was conducted on 1,198 women aged 20-44 who had experienced deliveries and 1,138 deliveries done during the period of 5 years from 1970 to 1974. The results obtained from the study for 2 months of June and July in 1975, in Keum-San Gun, Chungeheongnam Do were abstracted as follow. 1) Of all respondents the group aged 35-39 years was the most frequent one (27.5%) and the one aged 20-24 years was the least (5.7%). 2) Regarding the respondents' and their husbands' educational back ground, the majority (62.4% and 55.8% respectively) had received primary school. The mean educational level of respondents' husbands was a little higher than that of respondents. 3) Most of the respondents' husbands (80.4%) in the study area were engaged in agriculure. 4) The ideal number of sons and daughters averaged 2.1 and 1.6 respectively. However the average number of pregnancies was 4.7. 5) The mean general fertility rate of the period of 5 years from 1970 to 1974 was 190.0. 6) The proportion approving of family planning was 84.7% and among them the current contraceptive use rate was 49.6%. 7) The largest proportion (30.5%) of respondents currently used contraception used IUDs. 8) Of all respondents who had experienced pregnancy in the past, 19.8% stated that they had experienced induced abortion. 9) The percentage of deliveries received prenatal care at medical facilities was 33.4% (16.5% at health center, 10.9% at clinics and 6.0% at midwife's home). 10) The rate of receiving prenatal care was increased in accordance with educational level of the respondents. 11) Of all deliveries, 97.3% was reported to have been delivered at home, while only 2.7% were delivered at a hospital of a midwife's home. 12) The percentage of deliveries attended by medical personnel was 9.8% (5.8% by physicians and 3.8% by midwives). 13) For severing the umbilical cord, sterilized scissors were used by 37.5% of respondents. Unsterilized sewing scissors were most frequently used (by 52.4%) as a tool for cutting umbilical cord. 14) Only 29.2% of parents registered the birth of their children within 14 days after birth and 51.3% within a month. 15) The rate of registration of birth was not correlated with the educational level of respondents and their husbands.
카드미움과 鉛의 同時投與가 白鼠臟器內의 含量과 酵素活性度 變化에 미치는 影響
高炳勳,車喆煥 고려대학교 의과대학 1981 고려대 의대 잡지 Vol.18 No.3
In order to study interaction of cadmium (Cd) and lead (Pb) when exposed at the same time, 1㎎/㎏ body weight of Cd and/or 1㎎/㎏ body weight of Pb were simultaneously inject into 78 adult rats of Spregue-Dswley Species intraperitonially every day for 10 to 60 days and their contents in liver, kidney and bone of the rats were measured at every 10 day-interval. The results were summarized as follows; 1. Kidney and liver which were the target organs of Cd were seemed to have been damaged since from 30th day after combined injection of Cd with Pb when maximum or critical concentration was shown, whereas it was shown from 60th day after injection of Cd only. 2. In case of Cd-Pb combined administration, concentration of Cd in bone tissue started increasing from 50th after initial administration, whereas it started from 30th day after in case of injection of Cd only. It was thought that Cd contained in liver and kidney would be transported to bone tissue after decreasement of accummulation rate in the kidney & liver. 3. The similar phenomena were also shown in case Pb accummulation showing remarkable decreasement of it after 40th day of combined injection of Cd and Pb. 4. Concentration of iron in liver of rats exposed to Cd and/or Pb became lower and lower as time went by compared with that of control group. Degree of decreasement was more severe in the group exposed to both of Cd and Pb at the same time. 5. Activity of LDH decreased from 10th day after the simultaneous injection of Cd with Pb, and it increased again at 50th day of experiment. And activity of alkaline-phosphatase started decreasing from 20th day after exposure of Cd and Pb.
뇌실내에 발생한 거대 석회화를 지닌 희돌기 교세포종 1례
고인관,김재민,백광흠,신형식,김영수,고용,오성훈,오석전,김남규,김광명 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.1
Primary intraventricular oligodendroglioma is uncommon and radiological calcification at that location is quite rare. We are reporting a case of hge primary calcified intraventricular oligodendroglioma in the trigone and occipital horn of the left lateral ventricle totally removed through a left parieto-occipital transcortical approach. The clinical, radiological and surgical details of the case are presented with review of literature.