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Geng Yan-Bo,Ding Zhao-Hua,Xiao Jing-Lin 한국물리학회 2021 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.79 No.1
In this work, the effect of parabolic potential on the properties of strongly coupled polaron in an asymmetric Gaussian quantum well (QW) has been studied. Relations of the frequency vibration and the strongly coupled polaron’s ground-state energy in an asymmetric Gaussian QW for RbCl crystals at different confinement strengths along the x and the y directions, the asymmetric Gaussian QW barrier heights, and the Gaussian confinement potential widths and temperatures have been studied using the Lee–Low–Pines unitary transformation and the linear combination operator methods. Calculations show that the absolute value of ground-state energy increased with increasing confinement strengths along the x and the y directions and asymmetric Gaussian QW barrier height, and derease with increeasing Gaussian confinement potential width, and temperature. In addition, vibrational frequency was found to decrease with increasing Gaussian confinement potential width and to increase with increasing confinement strengths along the x and the y directions, asymmetric Gaussian QW barrier height, and temperature. The five parameters involved in this paper are important physical quantities for studying the properties of Gaussian QWs, and have important physical significance for the study of nanomaterials.
Isoprenaline Induces Periostin Expression in Gastric Cancer
Lin Chen,Guo-Xiao Liu,Hong-Qing Xi,Xiao-Yan Sun,Zhi-Jun Geng,Shao-Wei Yang,Yan-Jie Lu,Bo Wei 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.3
Purpose: Periostin mediates critical steps in gastric cancer and is involved in various signaling pathways. However, the roles of periostin in promoting gastric cancer metastasis are not clear. The aim of this study was to investigate the relevance between periostinexpression and gastric cancer progression and the role of stress-related hormones in the regulation of cancer development and progression. Materials and Methods: Normal, cancerous and metastatic gastric tissues were collected from patients diagnosed with advanced gastric cancer. The in vivo expression of periostin was evaluated by in situ hybridization and immunofluorescent staining. Meanwhile,human gastric adenocarcinoma cell lines MKN-45 and BGC-803 were used to detect the in vitro expression of periostin by using quantitative real-time polymerase chain reaction (PCR) and western blotting. Results: Periostin is expressed in the stroma of the primary gastric tumors and metastases, but not in normal gastric tissue. In addition,we observed that periostin is located mainly in pericryptal fibroblasts, but not in the tumor cells, and strongly correlated to the expression of α-smooth muscle actin (SMA). Furthermore, the distribution patterns of periostin were broader as the clinical staging of tumors progressed. We also identified a role of stress-related signaling in promoting cancer development and progression,and found that isoprenaline upregulated expression levels of periostin in gastric cancer cells. Conclusion: These findings suggest that the distribution pattern of periostin was broader as the clinical staging of the tumor progressedand found that isoprenaline upregulated expression levels of periostin in gastric cancer cells.