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      • SCIESCOPUSKCI등재
      • SCOPUSKCI등재

        방사선조사가 설의 개방성창상치유에서 섬유아세포의 재형성에 미치는 영향에 관한 연구

        최순철,박태원,유동수,이진구 大韓口腔顎顔面 放射線學會 1997 Imaging Science in Dentistry Vol.27 No.1

        Radiation-impaired wound healing in animal experiments was believed to be an another logical experimental model to understand the wound healing mechanism in patients. The purpose of this study was to reveal the block point which would result in impaired healing. Twenty four rats(Sprague-Dawley strains) were divided into two groups according to the time interval between irradiation and wounding. Group I, observing the healing effect on the lst day and GroupⅡ are the healing effects on the 7th days after irradiation to the wound of the rat tongue. Experimental animals were sacrificed 3, 6, 12, and 24 hours after wounding. The specimens were examined by the light microscope and transmission electron microscope. The following results were obtained 1. Fibroblasts in both groups showed degenerative changes which were dilated mitochondria and rER, reduced microorganelle, vacuoles and little cytoplasmic process. 2. Average length between bands and quantity of the newly produced collagen fibers around fibroblasts remained unchanged against control group. 3. The severity of degenerative change of the fibroblast and impairment of wound healing including shortening of the thickness of collagen fibers were more severe in the group Ⅱ than in the group I.

      • 음양오행의 공학적 해석에 의한 체질 분류 및 섭생법

        최혜선,김혜숙,신미수,장동순 忠南大學校 環境問題硏究所 1997 環境硏究 Vol.15 No.-

        This paper describes the application of Yin-Yang & Five Element Theory for the prevention and diagnosis of diseases due to environmental pollution by the scientific interpretation of the basic properties of five elements. The five elements considered are Mok(木,wood), Hwa(火,fire), To(土,soil), Geum(金,metal), SU(水,water). The basic properties of these are explained as warm energy, explosively dispersive heat, agglomerating force, tension or crystallization force, and finally cool & soft energy respectively. Utilizing these basic properties, the constitution classification can be modeled by the shape of face, which is attributed by the relative strength of the major organs, that is, five elements. Further, the vulnerable disease according to the constitution are briefly described together with the therapy method by diet, especially emphasizing the taste of food.

      • SCOPUSKCI등재

        측두하악관절내장증에서 하악과두운동과 측두하악관절조영상의 상호관계

        최순철,박태원,유동수,이은숙 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

        Arthrography of the temporomandibular joint is a useful method of demonstrating the soft tissue abnormalities related to disc dysfunction. In this study, 19 asymptomatic joints, 31 joints with anterior disc displacement with reduction, 31 joints with anterior disc displacement without reduction which were classified by arthrotomography under fluoroscopy were evaluated to determine the linear measurement of anterior recess of inferior joint space and the relationship between the condylar anterior translation and the severity of the internal derangements. Their fluoroscopic images were also evaluated to describe the characteristics of condylar paths in internal derangements of the temporomandibular joints. The results were as follows; 1. The mean lengths of the anterior recess in asymptomain group, reduction group, and non-reduction group were 8.7±1.6㎜, 11.2±1.7㎜, 12.8±1.7㎜ respectively. The length of the anterior recess was increased according to the severity of the internal derangements(p<0.05). 2. Linear measurements of anterior movement of condyle on maximum mouth opening were 13.1±4.2㎜, 15.9±4.1㎜, 5.0±3.7㎜ in asymptomatic group, reduction group, and non-reduction group respectively. Compared with aymptomatic group, reduction group showed hypermobolity of the condyle and non-reduction group showed hypomobility. 3. Condyles moved beyond the crest of articular eminence in 80% of reduction group and did not reach it in 70% of non-reduction group. 4. The condyle moved mainly superiorly in reduction group(66%) and horizontally in asymptomatic group(47%). There were no cases to move superiorly in non-reduction group.

      • SCOPUSKCI등재

        서울대학교 치과대학 구강악안면방사선학교실

        최순철,고재희,박태원,유동수,이삼선 大韓口腔顎顔面 放射線學會 1997 Imaging Science in Dentistry Vol.27 No.1

        The aneurysmal bone cyst is a nonmalignant reactive bone lesion. Developing rarely in the craniofacial region, and more commonly affecting the long bones and the spine, the lesion has variable etiopathogenic characteristics. The authors diagnosed a 33-year-old female as aneurysmal bone cyst after undergoing clinical, radiological and histological examinations. The characteristics were as followed: 1. The patient complained of pain and swelling of the right preauricular area. 2. The conventional radiograms showed a relatively well defined radiolucent lesion with partially scalloping margin. The cortical bone of the right condyle was thinned and expanded by the lesion. 3. Bone scintigraphy with ?Tc demonstrated ring-like or doughnut-pattern accumulation of radioactivity. 4. On T1-weighted imaging of MRI, the lesion on the right condyle had middle signal intensity. T2-weighted MRI demonstrated multiple high signal intensities separated by septa which had low signal intensity. Finger in ballon appearance was seen. 5. Histologically, the lesion was composed of large sinusoidal blood spaces lined by fibroblasts and histiocytes. Its fibrous stroma consisted of fibroblstic element, multinucleated giant cells, extravasated erythrocytes and focal hemosiderin pigmentation. New bone formation was also observed around larger sinusoidal spaces.

      • 3-Amidino-3-Aza-A-home-5-α-cholestane의 합성

        崔舜圭,成大東 東亞大學校 1981 東亞論叢 Vol.18 No.1

        The intermediate, 3-Aza-A-homo-5α-cholestane required for the synthesis of 3-Amidino-3-Aza-A-homo-5α-cholestane was obtained through a reaction of 3-Aza-A-homo-5α-chlestane-4-one with Lithium aluminium hydride. The reaction of 3-Aza-A-homo-5α-cholestane with 2-methy-2-pseudothioureasulfate provided the title compound at ca. 150∼180℃ under slightly reduced prossure for 75 min. without any solvents. The Aza-steroid containing an amidine moiety was prepared in this study. The amidine group is active species of antihypertensive thus the title compound is expected antihypertensive activity.

      • Nucleophilic Substitution Reaction of Dabsyl Chloride with p-Substituted Anilines

        嚴泰燮,崔舜圭,成大東,韓性彬 東亞大學校 大學院 1985 大學院論文集 Vol.10 No.-

        염화답실과 치환아닐린과의 친핵성 치환반응을 여러 용매계에서 진행시키고 이때의 반응속도 상수를 결정하였다. Br?nsted β값과 Hammett ρ?값들의 결과로부터 전이상태에서 결합파괴보다 결합형성이 우선함을 알 수 있었다. 분광용매화 상관관계식으로부터 용매의 수소결합주게(HBD) 산도 값(α)의 기여도 보다 용매의 편극-극성값(π?)의 기여도가 더 크게 작용함으로서 전이상태에서 결합 형성에 용매의 작용이 큼을 알았다. 또한 Dansyl과 Bansyl의 산 염화물보다 속도상수값이 크게 관측되어지는데 이것은 친핵체가 반응기질의 평면에 수직되게 공격함으로써 전이상태가 더욱 안정화되기 때문이며 이느 Marcus의 전이상태이론에서 concerted mechanism이 작용함을 의미한다 하겠다.

      • 결핵균체 단백항원에 대한 항결핵균 IgG 항체에 관한 연구

        최대경,백태현,권지순,심운택,이동배 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

        In order to study the level of IgG antibody binding to sonicate antigen of Mycobacteriumn tuberculosis H_34Rv for ammonium sulfate 30∼40 fraction in sera isolated from 209 patients and. 135 controls were measured by plastic tube enzyme-linked immunosorbent assay (ELISA). The levels of IgG antibody binding to Mycobacterium tuberculosis H_37Rv antigen in sera from all patients and controls were measured after absorption of 1 : 400 diluted sera with ,Wycobacteriuez bovis and dMlycobacterium Kansasii for ammonium sulfate 30∼40 fraction. The authors conducted the survey from August 1984 to January 1985. The results obtained were as follows : 1. At the serum dilution of 1:400, the mean ELISA values of IgG antibody to Mycobacterium tuberculosis H_37Rv after absorption with Mycobacterium kansasii antigen from far advanced patients and control were 0.8666±0.4903 and 0.2058±0.1353, respectively. 2. The mean ELISA value of IgG antibody to Mycobacterium tuberculosis H_37Rv afer absorption with Mycobacterium kansasii antigen from moderate patients was 0.6488±0.3918, the ratio of ammonium sulfate fraction 30∼40 in sera from patients and controls was 3.153. 3. The mean ELISA value of IgG antibody to Mycobacterium tuberculosis H_37Rv after absorption with Mycobacterium kansasii antigen from minimal patients was 0.4205±0.3155, the ratio of ammonium sulfate fraction 30∼40 in sera from patients and controls was 2.043.

      • 松果體芽細胞腫 1例

        崔淳官,李仁洙,李東華,姜得龍 순천향의과대학 1979 Journal of Soonchunhyang Medical Science Vol.2 No.3

        Neoplasms of the pineal gland are collectively rare, comprising from 0.4 to 1% of all tntracranial tumors, among them the number of pinealoblastoma is extremely small. A case of pinealoblastoma is reported. A 25-year old female with headache, Parinaud's syndrome and voiding disturbance of 1 month's duration is presented. Neurological findings were the vilateral papilledemas and the bilateral pareses of upward gaze. Vertebral angiography, Conray ventriculography and C-T brain scan revealed a posterior 3rd ventricle tumor. Through the right occipital approach a soft pinkish-grey mass on the pineal region was detected, and biopsy was kone. At the same time ventriculoperitoneal shunt was applied. The pathological finding of the specimen was pinealoblastoma. The patient underwent the radiation therapy with good result.

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