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      • Calculations of AC magnetic losses from the experimental field profiles in various types of coated conductors under applied fields

        Yoo, J,Lee, S,Jung, Y,Lee, J,Youm, D,Ha, H,Kim, H,Ko, R-K,Oh, S Institute of Physics 2008 Journal of physics. Conference series Vol.97 No.1

        <P>We measured the field profiles, <I>H</I>(<I>x,H</I><SUB>a</SUB>) s, near the surface of coated conductors (CCs) by using the scanning Hall probe method. The samples were SmBCO-CC tape fabricated by co-evaporation method and YBCO-CC tape fabricated by PLD method. The applied fields, <I>H</I><SUB>a</SUB>s, were decreased from <I>H</I><SUB>peak</SUB>to -<I>H</I><SUB>peak</SUB> stepwise. From the values of <I>H</I>(<I>x,H</I><SUB>a</SUB>), we calculated the current profiles, <I>J</I>(<I>x,H</I><SUB>a</SUB>) s, by the inversion method. From the values of <I>J</I>(<I>x,H</I><SUB>a</SUB>) and the corresponding flux densities, we calculated the hysteretic energy losses per cycle, <I>Q</I><SUB>M</SUB>s, for various <I>H</I><SUB>peak</SUB>s. From the values of <I>Q</I><SUB>M</SUB>, we calculated the characteristic functions, <I>g</I>s, by using the relation, <I>g</I>= π<I>Q</I><SUB>M</SUB>/μ<SUB>0</SUB><I>I</I><SUP>2</SUP><SUB>c</SUB>. Here, <I>I</I><SUB>c</SUB> is the critical current. For the range of <I>H</I><SUB>peak</SUB>/<I>H</I><SUB>c</SUB>≤ 3, the <I>g</I>-values of SmBCO CC tape were larger than those of YBCO CC tape. However, for the range of <I>H</I><SUB>peak</SUB>/<I>H</I><SUB>c</SUB> ≥ 3, the <I>g</I>-values of SmBCO CC tape were smaller than those of YBCO CC tape. When <I>H</I><SUB>peak</SUB>/<I>H</I><SUB>c</SUB> = 3, both sample show almost same value of <I>g.</I>However we found qualitatively different <I>J–B</I> hysteretic curves for both samples. We also compared our <I>g</I>-values with other <I>g</I>-values, which were directly measured by energy loss experiments. Our <I>g</I>-values of YBCO CC tapes were basically similar to the Brandt's theoretical values of <I>g</I> in the most range of <I>I</I><SUB>peak</SUB> in our measurements.</P>

      • Integrin αvβ3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line

        Kim, D.S.,Jeon, O.H.,Lee, H.D.,Yoo, K.H.,Kim, D.S. Academic Press 2008 Biochemical and biophysical research communication Vol.377 No.2

        We have previously reported that a disintegrin inhibits solid tumor growth and metastasis in mouse model [I.C. Kang, Y.D. Lee, D.S. Kim, A novel disintegrin salmosin inhibits tumor angiogenesis, Cancer Res. 59 (1999) 3754-3760; S.I. Kim, K.S. Kim, H.S. Kim, D.S. Kim, Y. Jang, K.H. Chung, Y.S. Park, Inhibitory effect of the salmosin gene transferred by cationic liposomes on the progression of B16BL6 tumors, Cancer Res. 63 (2003) 6458-462]. In this study, we have investigated the modulatory effect of a disintegrin, saxatilin, on the balance between MMP-9 and tissue inhibitor of metalloproteinase-1 (TIMP-1) in human ovarian cancer cell line MDAH 2774. Functional mechanism of the disintegrin-mediated transcriptional regulation of MMP-9 and TIMP-1 was examined in the ovarian cancer cell line. Saxatilin strongly induced TIMP-1 expression in dose- and time-dependent manners, while the disintegrin suppressed MMP-9 expression. Further analyses clearly indicated that interaction of the disintegrin and integrin αvβ3 results in the TIMP-1 promoter activation via c-fos to suppress TNF-α-induced cancer cell invasion. These results demonstrate that integrin αvβ3-mediated transcriptional regulation of MMP-9 and TIMP-1 is critical for suppressing the ovarian cancer cell invasion.

      • SCIESCOPUSKCI등재

        Effect of the Length of Feed Withdrawal on Weight Loss, Yield and Meat Color of Broiler

        Kim, D.H.,Yoo, Y.M.,Kim, S.H.,Jang, B.G.,Park, B.Y.,Cho, S.H.,Seong, P.N.,Hah, K.H.,Lee, J.M.,Kim, Y.K.,Hwang, I.H. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.1

        The current study was conducted to determine the optimum length of feed withdrawal for pre-harvest broilers. A total of three hundred broilers were sampled from an industrial population, and 30 chicks for each weight group (e.g., 1.5 and 2.5 kg) were randomly assigned to feed withdrawal treatments for 0, 3, 6, 9 and 12 h. Weight loss, yield, muscle pH, objective meat color and weights of gastro intestinal contents, crop, gizzard, provenriculus, small intestine, caecum, and rectum were determined. Live weight loss was significantly (p<0.05) increased as length of feed withdrawal extended. A significant (p<0.05) carcass yield for both 1.5 and 2.5 kg groups coincided after 9 and 6 h feed withdrawal, respectively. Net weights of intestinal contents for crop and gizzard were significantly (p<0.05) reduced by 6 h, and the reduction for proventriculus and small intestine occurred from 3 h. A noticeable effect of feed withdrawal on pH for breast muscle at 3 h postmortem occurred only when chicks were fasted for 3 h of which pH (6.05) was significantly (p<0.05) higher than that for other groups including the control (5.74). There was a linear tendency of higher lightness (Hunter L* value) numerically for chicks fasted for longer periods. The highest coefficient of determinations of regression models to estimate weight loss as a function of fasting period and body weights were achieved, when the models included both linear and quadratic terms for fasting period, and linear term for both 1.5 ($R^2=0.76$) and 2.5 kg ($R^2=0.78$) body weight groups. Given the practical aspect, approximately 1.5 kg of body weight is dominant, weight loss could be predicted by the following function; live weight $loss=26.6-0.28{\times}(fasting period)^2+12.34{\times}pasting\;period-0.012{\times}body\;weight$, $R^2=0.76$. Current data implied that the optimum fasting time for pre-slaughter chicks varied depending on slaughter weight; 6 and 9-h fasting were recommendable for 2.5 and 1.5 kg chicks, with little effect on objective meat color.

      • SCIESCOPUSKCI등재

        Effects of Egg Yolk Antibodies Produced in Response to Different Antigenic Fractions of E. coli O157:H7 on E. coli Suppression

        Chae, H.S.,Singh, N.K.,Ahn, C.N.,Yoo, Y.M.,Jeong, S.G.,Ham, J.S.,Kim, D.W. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.11

        The objective of this research was to provide the characterization and method for producing anti-E. coli O157:H7 antibodies in egg-laying hens and to determine if the antibody can restrain the proliferation of E. coli O157:H7 in-vitro. Selected antigenic fractions (whole cell, outer membrane protein and lipopolysaccharide (LPS)) from E. coli O157:H7 were injected to hens in order to produce anti-E. coli O157:H7 antibodies. The immune response and the egg yolk antibodies of laying hens against the whole cell, outer membrane protein and LPS antigens were monitored by ELISA. The level of antibodies against whole cell antigen monitored through ELISA sharply increased after the initial immunization, and it was found to be maximum on day 49 however, the level was maintained up to day 70. Antibodies (5 mg/ml) directed against the whole cell inhibited E. coli proliferation 10-13 times more than outer membrane protein or LPS. The antibody response against the whole cell antigens appeared to have higher activity in restraining the proliferation of E. coli O157:H7 than antibody against outer membrane protein or LPS. Results reflected that increasing the IgY's in the egg yolk could prevent greater economic losses due to human and animal health from pathogenic bacteria i.e. E. coli O157:H7.

      • Valeriana officinalis extract and its main component, valerenic acid, ameliorate d-galactose-induced reductions in memory, cell proliferation, and neuroblast differentiation by reducing corticosterone levels and lipid peroxidation

        Nam, S.M.,Choi, J.H.,Yoo, D.Y.,Kim, W.,Jung, H.Y.,Kim, J.W.,Kang, S.Y.,Park, J.,Kim, D.W.,Kim, W.J.,Yoon, Y.S.,Hwang, I.K. Pergamon Press ; Elsevier Science Ltd 2013 Experimental Gerontology Vol.48 No.11

        Valeriana officinalis is used in herbal medicine of many cultures as mild sedatives and tranquilizers. In this study, we investigated the effects of extract from valerian root extracts and its major component, valerenic acid on memory function, cell proliferation, neuroblast differentiation, serum corticosterone, and lipid peroxidation in adult and aged mice. For the aging model, d-galactose (100mg/kg) was administered subcutaneously to 6-week-old male mice for 10weeks. At 13weeks of age, valerian root extracts (100mg/kg) or valerenic acid (340μg/kg) was administered orally to control and d-galactose-treated mice for 3weeks. The dosage of valerenic acid (340μg/kg), which is the active ingredient of valerian root extract, was determined by the content of valerenic acid in valerian root extract (3.401+/-0.066mg/g) measured by HPLC. The administration of valerian root extract and valerenic acid significantly improved the preferential exploration of new objects in novel object recognition test and the escape latency, swimming speeds, platform crossings, and spatial preference for the target quadrant in Morris water maze test compared to the d-galactose-treated mice. Cell proliferation and neuroblast differentiation were significantly decreased, while serum corticosterone level and lipid peroxidation in hippocampus were significantly increased in the d-galactose-treated group compared to that in the control group. The administration of valerian root extract significantly ameliorated these changes in the dentate gyrus of both control and d-galactose-treated groups. In addition, valerenic acid also mitigated the d-galactose-induced reduction of these changes. These results indicate that valerian root extract and valerenic acid enhance cognitive function, promote cell proliferation and neuroblast differentiation, and reduce serum corticosterone and lipid peroxidation in aged mice.

      • CAN통신을 이용한 H-브릿지 멀티레벨 인버터의 PWM 동기화 및 위상전이 방법

        박영민(Y.M.Park),유한승(H.S.Yoo),장성영(S.Y.Jang),이현원(H.W.Lee),이세현(S.H.Lee),서광덕(K.D.Seo) 전력전자학회 2004 전력전자학술대회 논문집 Vol.- No.-

        H-브릿지 멀티레벨 인버터는 여러 개의 단상 Power Cell을 직렬로 연결함으로써 저전압 전력용 반도체를 사용하여 고전압을 얻을 수 있고, 정현파에 가까운 출력전압 파형을 얻을 수 있는 멀티레벨 인버터 토폴로지이다. 본 토폴로지는 출력전압 레벨에 비례하여 Power Cell의 수가 증가하므로, 주제어기의 연산능력에 대한 부담증가와 신호선의 많아지는 단점이 있다. 따라서 Power Cell제어를 직접적인 PWM 신호가 아닌 통신을 사용함으로써 이러한 단점을 극복할수 있으며, 신뢰성 측면이나 보수/유지 측면에서도 유리하다. 본 논문은 산업현장에서 신뢰성을 인정받아 많이 사용되고 있는 직렬통신 방식의 일종인 CAN통신 인터럽터를 이용한 H-브릿지 멀티레벨 인버터 Power Cell의 PWM 동기화 및 위상전이 방법에 관한 것이다. 제안된 방법의 주요 장점은 주제어기와 셀 제어기 사이에 직렬통신(CAN)을 사용함으로써 주제어기와 셀 제어기의 신호선의 단순화, 주제어기의 부담 감소, Power Cell의 모듈화, 셀 단위의 보호동작 용이, 확장성 향상 그리고 제어 신호 및 Power Cell의 신뢰성을 향상에 있다. 13레벨로 구성된 H-브릿지 멀티레벨 인버터 시험을 통해 제안된 방법의 타당성과 신뢰성을 입증하였다.

      • Iron oxide/porous carbon as a heterogeneous Fenton catalyst for fast decomposition of hydrogen peroxide and efficient removal of methylene blue

        Yoo, S.,Jang, D.,Joh, H. I.,Lee, S. Royal Society of Chemistry 2017 Journal of Materials Chemistry A Vol.5 No.2

        <P>A high performance Fe3O4/Fe/Fe3C@PCNF heterogeneous Fenton catalyst was synthesized for aqueous H2O2 decomposition and was utilized to remove methylene blue in water. Surprisingly, Fe3O4/Fe/Fe3C@PCNF showed an extremely fast decomposition rate; this rate ranked as the highest value reported to date. Furthermore, it showed efficient removal of methylene blue in water which was tested at different H2O2 concentrations and solution temperatures. Based on detailed characterization, several unique features of this catalyst were presumed to be responsible for its remarkable catalytic activity for H2O2 decomposition as follows: (1) the presence of Fe-0 and delocalized pi-electrons of graphitic layers promotes the reduction of Fe3+ to Fe2+; (2) the catalyst particles were partially covered with a few defective graphitic layers, and H2O2 decomposition could occur through these defects; (3) the defective graphitic layers partially covered the catalyst particle to force the decomposition reaction to occur only in the vicinity of carbon and Fe3O4. Finally, this presumption was proved through experiments by changing the activation time of Fe3O4/Fe/Fe3C@PCNF. After H2O2 decomposition was completed, Fe3O4/Fe/Fe3C@PCNF could be efficiently separated by an external magnetic field because of its ferromagnetic behavior. Fe3O4/Fe/Fe3C@PCNF showed high removal activity of aqueous methylene blue tested under various conditions.</P>

      • 임상 각과에서 의뢰된 환자의 염색체 검사분석에 관한 고찰

        유훈,이권해,조태호,이동화,문원실,차상헌 순천향대학교 1989 논문집 Vol.12 No.3

        The karyotypes were obtained from 200 cases who had been referred for suspected chromosomal abnormalities to cytogenetic laboratory in Soonchunhyang University Hospital from January. 1987 to June. 1989. Out of 200 cases, 36 cases had the abnormal karotypes and the others had normal karyotypes. Among the 36 chromosomal anomalies, there were the autosomal anomalies in 14 cases(38.9%), the sex chromosomal anomlies in 10 cases(27.8%) and normal autosomal variation in 12 cases(33.3%). The results were obtained as follows: 1. Autosomal anomalies 1) 21 trisomy 7 cases 2) 18 trisomy 2 cases 3) Philadelphia chromosome 1 case 4) 45, XX, t(14q 21q) 2 cases 5) 46, XX, t(7:15)(q36:23) 2 cases 2. Sex chromosomal anomalies 1) 47, XXY 1 case 2) 45, X/ 46, XY 1 case 3) 45, X 2 cases 4) 45, X/ 46, Xi(Xq) 2 cases 5) 46, X,i(Xq) 1 case 6) T. F. Syndrome 2 cases 7) del(X)(q25) 1 case 3. Normal Autosomal variation 1) inv 9(p11 q21) 5 cases 2) 1 qh+ 1 case 3) 13 p+ 2 cases 4) 14 p+ 2 cases 5) 22 p+ 2 cases

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