말기환자 관리에 대한 의사들의 태도

최윤선,김장욱,신승욱,이영미,이태호,홍명호 가톨릭대학교 가톨릭대학교 간호대학 호스피스 교육연구소 1998 호스피스논집 Vol.3 No.-

Background : Nowadays, it is possible to prolong the life. And to improve the quality of life of the dying patients, they need to receive not only the physical, pscychological, social and spiritual care but also comprehensive and continuous care. Also, doctors have to consider many ethical issues especially in the dying patients. The purpose of this study is to analyze the doctors' attitude of those ethical issues and emphasize the importance of hospice. Methods : During September 1996, doctors who worked for a university hospital participated in this study by responding to the pre-made questionnaire. It dealt with the most suffering pain, the preferred death place, the use of life maintaining equipments, the application of cardiopulmonary resuscitation(CPR) to terminal patients and the doctors' experience and attitude euthanasia. Results : ① The most suffering symptom in dying patients was pain(60.0%). ② The death place was recommended by doctors was home(58.8%) and hospital (15.4%) in order. ③ 56.9% of doctors answered 'the life maintaining equipments isn't needed', 29.2% of doctors answered' according to the case', and 'needed' was 12.3%. ④ The application of CPR to the terminal patients, without the DNR chart, the only 15.4% of doctors answered "Do not CPR." But with the DNR chart, the percents of 'Do not CPR' was increased to 69.2%. The resident group did more CPR than specialist group(p<0.01). ⑤ The 50.8% of doctors agreed with the passive euthanasia. Conclusions : Many doctors follow the family member's opinion in the ethical issues of the dying patients. Euthanasia is forbidden by the law in Korea, but many doctors agree with the passive euthanasia. Hospice can solve the debating ethical issues including the euthanasia.

국내 여성복 브랜드 그레이딩의 연령별 비교에 관한 연구Ⅰ

최윤선,김소라,송미령 服飾文化學會 2002 服飾文化硏究 Vol.10 No.4

The purpose of this study was to research grading work to the targets of women's wear manufacturers in Korea. For the questionnaire, 91 women's wear brands, which were in higher ranking of sales, were selected, and the age groups were separated into 3: 29's 30's, and 40's & 50's, according to their customers. The graders of each brand were questioned about 20 items for this research. The results of the questionnaire were as follows: 1. The brands for older women manufactured more sizes and cared more about somatotypes for grading than other brands did. 2. For upper garments on the basis of bust girth, the numbers of dimensional increments were different depending on the age groups: 9 for 20's, 7 for 30's, and 7 for 40's & 50's. 3. For lower garments on the basis of hip girth, the number of dimensional increments were different depending on the age group: 9 for 20's, 6 for 30's, and 5 for 40's & 50's. 4. As a model size of grading, many brands used the smallest size, but the brands for 40's & 50's also used the second size. 5. the parts needed to be corrected after grading were sleeve ease, armhole, shoulder line, neckline, crotch curve, etc. The grading with CAD system had more correction after grading than hand grading.

국내 여성복 브랜드 그레이딩의 연령별 비교에 관한 연구 Ⅱ

최윤선,김소라,송미령 服飾文化學會 2002 服飾文化硏究 Vol.10 No.5

The purpose of this study was to research specific dimensional increments of grading and to support to establish a grading system according to the targets of women's wear manufacturers in Korea. For the questionnaire, 91 women's wear brands, which were in higher ranking of sales, were selected, and the age groups were separated into 3: 20's, 30's, and 40's & 50's, according to their customers. The graders of each brand were questioned about specific dimensional increments of grading for this research. The results of the study were as follows: 1. Using the most common dimensional increments, 3.81cm(1½ inch) and 5.08cm(2 inch) for upper garments and lower garments, the modes of increments and reference increments for each garment section were suggested. 2. For upper garments, the brand for older women made larger increments of waist girth than for bust girth. This was to cover abdominal obesity. Also, the brands mede larger increments of girth than for shoulder breadth. 3. For lower garments, the brands for older women made larger increments of waist girth than for hip girth. It mean the drop value of hip girth minus waist girth was smaller. The breadths of front and back crotch were also wider.

2,4-D 處理가 'Harcot' 살구와 '美白' 복숭아의 果實 成熟과 品質에 미치는 影響

윤철구,김영호,임상철,김학현,이철희,최관순,김선규 충북대학교 농업과학기술연구소 1999 農業科學硏究 Vol.16 No.-

Effect of 2,4- D application on the fruit maturity and quality of 'Harcot' apricot and 'Mibaek' peach was examined. Leaf area of 'Harcot' apricot was not affected by 2,4-D while that of 'Mibaek' peach was increased by 35mg · L-1 2,4-D. Application of 2,4-D at 35mgㆍL-1 increased the fruit weight of both species, and that of 'Harcot' was doubled. Soluble solids content of 'Harcot' was decreased by 2,4-D while that of 'Mibaek' was not affected. Fruit maturity of 'Harcot' and 'Mibaek' was enhanced for respective 4 and 1 day by 2,4-D application. Percent fruit cracking of 'Harcot' apricot was decreased by 35mg · L-1 2,4-D.

환경 오염물질의 진보된 독성 평가 기법

류재천,최윤정,김연정,김형태,방형애,송윤선 한국환경독성학회 1999 환경독성보건학회지 Vol.14 No.1

Recently, several new methods for the detection of genetic damages in vitro and in vivo based on molecular biological techniques were introduced according to the rapid progress in toxicology combined with cellular and molecular biology. Among these methods, mouse lymphoma thymidine kanase (tk) gene forward mutation assay, single cell gel electrophoresis (comet assay) and transgenic animal and cell line model as a target gene of lac I (Big Blue) and lac Z (Muta Mouse) gene mutation are newly introduced based on molecular toxicological approaches. The mouse lymphoma tk^(+/-) gene assay (MOLY) using L5178Y tk+i- mouse lymphoma cell line is one of the mammalian forward mutation assays, and has many advantages and more sensitive than hprt assay. The target gene of MOLY is a heterozygous tk^(+/-) gene located in 11 chromosome, so it is able to detect the wide range of genetic changes like point mutation, deletion, rearrangement, and mitotic recombination within tk gene or deletion of entire chromosome 11. The comet assay is a rapid, simple, visual and sensitive technique for measuring and analysing DNA breakages in mammalian cells. Also, transgenic animal and cell line models, which have exogenous DNA incorporated into their genome, carry recoverable shuttle vector containing reporter genes to assess endogenous effects or alteration in specific genes related to disease process, are powerful tools to study the mechanism of mutation in vivo and in vitro, respectively. Also in vivo acridine orange supravital staining micronucleus assay by using mouse peripheral reticulocytes was introduced as an alternative of bone marrow micronucleus assay. In this respect, there was an International workshop on genotoxicity procedure (IWGTP) supported by OECD and EMS (Environmental Mutagen Society) at Washington D, C, in March 25-26, 1999. The objective of IWGTP is to harmonize the testing procedures internationally, and to extend to finalization of OECD guideline, and to the agreement of new guidelines under the International Conference of Harmonization (ICH) for these methods mentioned above. Therefore, we introduce and review the principle, detailed procedure, and application of MOLY, comet assay, transgenic mutagenesis assay and supravital staining micronucleus assay.

化學反應蒸着에 의한 CdS 多結晶 薄膜制作 및 그 特性硏究 (Ⅰ)

강현식,남궁윤,최선우,홍광준,최용대 全北大學校 敎育大學院 1986 敎育論叢 Vol.6 No.-

CdS thin film was fabricated by chemical bath deposition method and polycrystallined by the proper heat treatment. The physical properties of the amorphous and polycrystal of CdS thin film were observed and calculated by measuring the X-ray diffraction patterns, optical absorption, transmission and photoconductivity. From the present experiments, we obtained the energy band gap of the CdS polycrystal thin film to be 2.42eV and the In donor impurity level to be 0.025 eV below the conduction band : Another result was to be a_o=4.13Å and c_o=6.75Å for lattice constants of the hexagonal structure. Also, we attempted it to find the possibility of the application to photosensor. To apply cds this film to the photosensor more sufficiently, further experiments are required to accumulate data on such problems.

Complementary and Alternative Medicine Use among Cancer Patients at the End of Life: Korean National Study

Choi, Jin-Young,Chang, Yoon-Jung,Hong, Young-Seon,Heo, Dae-Seog,Kim, Sam-Yong,Lee, Jung-Lim,Choi, Jong-Soo,Kang, Ki-Mun,Kim, Si-Young,Jeong, Hyun-Sik,Lee, Chang-Geol,Choi, Youn-Seon,Lim, Ho-Yeong,Yun, Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objectives: To investigate in depth the use of complementary and alternative medicines (CAMs) by cancer patients at the end-of-life (EOL) and how they communicate with physicians about them. Design and location: In 17 hospitals in Korea between January and December 2004 we identified 4,042 families of cancer patients. Results: The prevalence of CAM use among cancer patients at the EOL was 37.0%, and 93.1% had used pharmacologic types of agents. The most frequent motive for CAM use was the recommendation of friends or a close relative (53.4%) or a physician (1.6%). Only 42.5% discussed CAM use with their physicians. Satisfaction with CAMS was recalled for 37.1%. The most common reason given for that satisfaction was improvement of emotional or physical well-being, while ineffectiveness was the most common reason given for dissatisfaction. The average cost of CAM during the last month of life was $US 900. CAM use was associated with longer disease periods, primary cancers other than liver, biliary, and pancreatic, and need of support from physicians or religion. Conclusions: CAM use among cancer patients at the EOL was common, not discussed with physicians, and associated with expectation of cure. Expectations were generally unmet while the treatments were a financial burden. Further studies evaluating the effects of CAM at the EOL and factors that enhance communication with the physician are needed.

Change in Patients' Satisfaction with Pain Control After Using the Korean Cancer Pain Assessment Tool in Korea

Choi, Youn Seon,Kim, Su Hyun,Kim, Jun Suk,Lee, Juneyoung,Kang, Jin Hyoung,Kim, Sam Yong,Kim, Si Young,Kim, Chul Soo,Song, Hong Suk,Lim, Ho Yeong,Yim, Chang Yeol,Chung, Ik Joo,Cho, Goon Jae,Lee, Myung Elsevier 2006 Journal of pain and symptom management Vol.31 No.6

<P><B>Abstract</B></P><P>Appropriate pain assessment is very important for managing cancer pain. This study was designed to evaluate the utility of the Korean Cancer Pain Assessment Tool (KCPAT) by assessing changes in the management of cancer pain. The changes in pain intensity, the pattern of drug prescriptions, and the patients' satisfaction with pain control were analyzed after using the KCPAT. The results indicated that pain medicine prescriptions were changed in 194 (51.5%) cases after using the KCPAT, and 69.5% of these changes were affected by the KCPAT. After using the KCPAT, pain intensity as assessed by the Visual Analogue Scale (VAS, 0–10cm) decreased (4.31±2.35 vs. 3.60±2.45, <I>P</I><0.0001), and the presence of associated symptoms and psychosocial items was significantly reduced. The patients' satisfaction with pain control was improved. Forty-four physicians (89.8%) thought that the KCPAT was useful. The KCPAT improved patients' satisfaction with pain control and was a useful tool for evaluating and managing cancer pain.</P>

삼황탕(三黃湯)이 LPS로 유도된 RAW 264.7 대식세포에서 항산화 및 항염증에 미치는 영향

최윤선 ( Youn-seon Choi ),김이화 ( Ee-hwa Kim ),이평재 ( Pyeong-jae Lee ),김용민 ( Yong-min Kim ) 대한미용학회(구 대한미용과학회) 2018 대한미용학회지 Vol.14 No.2

Samhwangtang (SHT) is being widely used in Korea and China for hundreds of years to treat inflammatory skin diseases. However, the mechanisms associated with SHT’s anti-oxidant and anti-inflammatory effects are still not clear. In the present study, we prepared aqueous extracts from SHT and performed cell viability, DPPH scavenging ability, nitric oxide(NO) production assay, real-time PCR and western blot (iNOS and COX-2). Results showed that cell viability in SHT did not decrease significantly compared to the normal group. Furthermore, the production ofNO decreased with SHT compared to the control group with LPS-stimulated RAW 264.7 macrophage cells. The amounts of iNOS and COX-2 expression decreased with SHT compared to the control group with LPS-stimulated RAW 264.7 macrophage cells. Moreover, we observed that SHT showed high DPPH free radical scavenging capability. In conclusion, SHT may be used as a new material of anti-oxidant and anti-inflammatory skin diseases.

Sero-epidemiological surveillance of Newcastle disease virus in wild birds in Korea during 2016-2018

Jong-Seon Jang,Hyun-Jeong Lee,So-Youn Youn,Hyun-Ah Kim,Kang-Seuk Choi,Yong-Kuk Kwon,Ji-Youn Lee 한국가금학회 2018 한국가금학회 정기총회 및 학술발표회 Vol.2018 No.10