KERI 2005 한국경제 분기 거시모형

허찬국(Huh Chan-Guk),김창배(Kim Chang-bae),이연호(Yeonho Lee) 한국경제연구원 2005 한국경제연구원 연구보고서 Vol.2005-19 No.-

The purpose of this study was to revise and supplement the ‘KERI-1997’ macroeconomic model in order to reflect changes in the internal and external environments of the Korean economy, particularly since in the foreign exchange crisis in 1997. The new model ‘KERI-2005’ created from this study is to be utilized in the future quarterly economic projections and policy analyses. The characteristics of the revised macroeconomic model are, first, it enables us to identify the way that taxation policy - income tax, corporate tax, tax exemptions on investments, etc. - spreads through the real economy and financial sectors via private consumption, investment, etc. and also to estimate its effects. Second, it enables us to predict the impact of government expenditure on the private sector differentially in terms of current expenditure and capital expenditure. Third, it makes it possible to analyze effects of monetary policy changes in terms of call interest rate rather than monetary aggregates on the real economy and the financial sector, reflecting the 1998 change in the Bank of Korea’s monetary policy procedure. Fourth, the external sector has a more rich specification. Especially by including the Chinese economy, which has emerged as the largest trading partner for Korea, we can gauge the impact of changes in China’s economic growth or yuan currency exchange rates on Korea. Some important policy implications obtained in the course of developing this model and policy simulation are as follows. First, lowering corporate tax rates is an effective countermeasure to the recent sharp investment slowdown. Policy simulations show that 1 percentage point cut in the tax rate would increase real GDP by up to 0.36% through facility expansion. Second, in the case of fiscal expenditure, the effect of capital expenditure appeared far greater than that of current expenditure. To enhance the efficiency of fiscal expenditure, therefore, the expenditure must be focused intensively on R&D or SOC investment, which are conducive to expansion of the growth potential, rather than on temporary pump-priming. Third, simulations show that a 0.25 percentage point cut in call interest rate increases real GDP by about 0.08~0.12% and consumer prices by 0.01~0.08%. This suggests that the BOK needs to be cautious in raising the short-term policy rate hike in the current situation where economic recovery is uncertain. Finally, the Chinese yuan’s appreciation appears to be disadvantageous to Korea's exports on the whole. Like many, our model is a somewhat fragile caricature of the complex economic system. Further improvements are in order in terms of estimation methodology (least squares) and the conceptual framework that is subject to the Lucas critique. We plan to make frequent revisions and upgrades. Also, results of policy analyses will be carefully interpreted.

Improved resolution in single-molecule localization microscopy using QD-PAINT

Chang Yeonho,Kim Do-Hyeon,Zhou Kai,Jeong Min Gyu,Park Soyeon,Kwon Yonghoon,Hong Triet Minh,Noh Jungeun,Ryu Sung Ho 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

Single-molecule localization microscopy (SMLM) has allowed the observation of various molecular structures in cells beyond the diffraction limit using organic dyes. In principle, the SMLM resolution depends on the precision of photoswitching fluorophore localization, which is inversely correlated with the square root of the number of photons released from the individual fluorophores. Thus, increasing the photon number by using highly bright fluorophores, such as quantum dots (QDs), can theoretically fundamentally overcome the current resolution limit of SMLM. However, the use of QDs in SMLM has been challenging because QDs have no photoswitching property, which is essential for SMLM, and they exhibit nonspecificity and multivalency, which complicate their use in fluorescence imaging. Here, we present a method to utilize QDs in SMLM to surpass the resolution limit of the current SMLM utilizing organic dyes. We confer monovalency, specificity, and photoswitchability on QDs by steric exclusion via passivation and ligand exchange with ptDNA, PEG, and casein as well as by DNA point accumulation for imaging in nanoscale topography (DNA-PAINT) via automatic thermally driven hybridization between target-bound docking and dye-bound complementary imager strands. QDs are made monovalent and photoswitchable to enable SMLM and show substantially better photophysical properties than Cy3, with higher fluorescence intensity and an improved resolution factor. QD-PAINT displays improved spatial resolution with a narrower full width at half maximum (FWHM) than DNA-PAINT with Cy3. In summary, QD-PAINT shows great promise as a next-generation SMLM method for overcoming the limited resolution of the current SMLM.

온침이 만성요통에 미치는 효과에 대한 무작위배정 대조군 예비 임상연구 프로토콜

서연호 ( Yeonho Seo ),김태오 ( Taeoh Kim ),조휘성 ( Whisung Cho ),고준혁 ( Junhyuk Ko ),안종현 ( Jonghyun Ahn ),김수전 ( Soo Jeon Kim ),이한솔 ( Hansol Lee ),장호경 ( Hokyung Chang ),김형석 ( Hyungsuk Kim ),김고운 ( Koh-woon Kim ) 한방재활의학과학회 2020 한방재활의학과학회지 Vol.30 No.4

Objectives This study is aimed to evaluate the feasibility of further clinical research of warm needle acupuncture as an effective and safe treatment for chronic low back pain. Methods Thirty participants will be randomly assigned to the Warm needle acupuncture group (n=15) and Dry needle acupuncture group (n=15). All patients will receive acupuncture therapy twice a week for 6 weeks, but only the experimental group will receive thermal stimulation. The primary outcome will be measured using the visual analogue scale for bothersomeness of low back pain, and the secondary outcome will be measured using the VAS for pain intensity, Oswestry disability index, 36-Item Short Form Health Survey, Beck's depression inventory, and amount of analgesics used. Conclusions The results of this study will be used to determine the feasibility of a future large-scale randomized controlled trial that provides clinical evidence for the efficacy and safety of warm needle acupuncture in the treatment of patients with chronic low back pain. (J Korean Med Rehabil 2020;30(4):155-164)

저온진공건조 공정에 제습제 적용을 위한 타당성 연구

심연호(Yeonho Sim),강지수(Jisu Kang),변시예(Siye Byun),장영수(Young Soo Chang),강병하(Byung Ha Kang) 대한설비공학회 2016 설비공학 논문집 Vol.28 No.5

This study was conducted to improve the performance of low-temperature vacuum dryer by applying desiccant to cold trap. Performance evaluation was carried out using several desiccants. The amounts of absorption and diffusivity were measured based on analytic model. Results of desiccant performance evaluation revealed that silica-gel had the most excellent performance for conditions of low-temperature vacuum drying process. Silica-gel was applied to cold trap for evaluating the drying performance. The experiment results showed that the drying time was extended as the thickness of sample was increased due to increased heat and mass transfer resistance of drying sample. In addition, as heating plate temperature was increased, drying time was decreased due to increased evaporation pressure of drying sample. Furthermore, drying time with desiccant was decreased approximately 20% than that without desiccant.

고용탄력성을 통해 살펴본 성장과 고용의 관계: 충북 사례를 중심으로

이연호(Yeonho Lee),이창민(Chang Min Lee) 한국경제연구학회 2020 한국경제연구 Vol.38 No.1

본 연구는 고용탄력성을 통하여 고용 없는 성장의 실태를 분석하고, 고용 창출 역량확충을 위한 정책적 시사점을 도출하였다. 1989∼2016년 16개 광역시․도 패널 자료를 이용하여 고용탄력성을 추정하고, 산업 간의 차이를 분석하였다. 추정모형은 패널 ARDL 공적분 모형을 이용하였으며, 시변(time varying) 계수 추정 기법을 적용해 고용없는 성장 문제가 일시적인 현상인지 구조적인 현상인지를 판단하여 보았다. 외환위기와 글로벌 금융위기 이후의 경제구조 변화가 고용탄력성에 미친 영향을 분석하였으며, 충북을 대상으로 지역별 차이에 대한 사례 연구도 진행하였다. 추정 결과, 서비스업이 제조업보다 장단기 고용탄력성 모두 훨씬 더 높았다. 장기 고용탄력성은 서비스업이 0.5970, 제조업이 0.3838이며, 단기 고용탄력성은 각각 0.5821, 0.3742로 추정되었다. 고용 없는 성장은 1990년대 중후반 제조업과 2000년대 초중반 전체 산업에서 특히 두드러지게 나타났던 문제였다. 하지만 최근에는 일자리가 성장에 민감하게 반응하는 등 고용탄력성이 높게 나타나고 있는데, 이는 저성장 시대 성장전략을 통한 일자리 창출이 여전히 중요한 과제임을 시사한다. This study analyzes the status of jobless growth based on employment elasticity and derives policy implications for expanding job creation capacity. Employment elasticity and its differences between industries were estimated with panel ARDL cointegration model applied to 16 metropolitan data from 1989 to 2016. The paper investigates whether the jobless growth problem is temporary or structural by applying time varying coefficients estimation. The study takes into account the effects of structural breaks in the aftermath of the Asian financial crisis and the global financial crisis on employment elasticity. Estimates show that service sector has far higher employment elasticity than manufacturing sector. The long-term employment elasticity was estimated to be 0.5970 for the service sector and 0.3838 for the manufacturing sector. Jobless growth is found to be a temporary problem in the manufacturing sector in the mid-to-late 1990s and in the entire industries in the early to mid-2000s. In recent years, however, employment elasticity has been rising, suggesting that job creation through growth strategies is still important in the era of low growth.

Dynamic-Simulation을 통한 영구자석형 횡자속 회전기의 인덕턴스 추정

김광운(KwangWoon Kim),김지원(JiWon Kim),정연호(YeonHo Jung),이지영(JiYoung Lee),강도현(DoHyun Kang),장정환(JungHwan Chang) 대한전기학회 2010 전기학회논문지 Vol.59 No.4

This paper presents Dynamic-Simulation to estimate the inductance of a permanent magnet type transverse flux rotating motor by applying the real-time parameter estimation theory. As transverse flux rotating motor has the complex structure, it can be happen to some errors between real value and designed one with respect to the inductance. To reduce this kinds of errors, the real-time parameter estimation theory was applied to dynamic-simulation. And then, By comparing the estimated inductance and designed one, it is realized that the real-time parameter estimation theory can be applied in the permanent magnet type transverse flux rotating motor.

Analysis of transient membrane protein interactions by single-molecule diffusional mobility shift assay

Jeong Min Gyu,Zhou Kai,Park Soyeon,An HyeongJeon,Kwon Yonghoon,Chang Yeonho,Kim Do-Hyeon,Ryu Sung Ho 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

Various repertoires of membrane protein interactions determine cellular responses to diverse environments around cells dynamically in space and time. Current assays, however, have limitations in unraveling these interactions in the physiological states in a living cell due to the lack of capability to probe the transient nature of these interactions on the crowded membrane. Here, we present a simple and robust assay that enables the investigation of transient protein interactions in living cells by using the single-molecule diffusional mobility shift assay (smDIMSA). Utilizing smDIMSA, we uncovered the interaction profile of EGFR with various membrane proteins and demonstrated the promiscuity of these interactions depending on the cancer cell line. The transient interaction profile obtained by smDIMSA will provide critical information to comprehend the crosstalk among various receptors on the plasma membrane.