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요통(腰痛) 환자에 대한 침치료(針治療)와 직접구(直接灸) 병행치료(竝行治療)에 대한 비교(比較) 연구(硏究)
위종성,원승환,황정수,선승호,안영민,손승현,박기철,박희수,We, Jong-sung,Won, Seung-hwan,Hwang, Jung-soo,Sun, Seung-ho,Ahn, Young-min,Sohn, Seung-hyun,Park, Ki-chul,Park, Hee-soo 대한침구의학회 2004 대한침구의학회지 Vol.21 No.6
Objective : The purpose of this report is to examine the effects of direct moxibustion in the Low back pain patient. Methods : Clinical studies were done 30 patients who were treated with low back pain to Dept. of Acupuncture & Moxibustion, of Oriental Medical Sang-Ji University from September 1, 2003 to August 31, 2004. We treated them by Oriental medical therapy(including direct moxibustion)for 10 days. The evaluation was performed five times(admission day, before and after each twice). Results : 1. VAS was decreased after direct moxibustion for 10 days significantly(p<0.01). 2. After direct moxibustion, S.L.R. T angle of patients were increased. ConclUsions : We brought to the conclusion that direct moxibustion has possibility to the efficient to cure the Low back pain. So we suggest the possibility to use this treatment for Low back pain.
Sung, Hwa Jung,Hong, Soon Cheol,Yoo, Ji Hyun,Oh, Jee Hyun,Shin, Hye Jin,Choi, In Young,Ahn, Ki Hoon,Kim, Sun Haeng,Park, Yong,Kim, Byung Soo The Korean Academy of Medical Sciences 2010 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.25 No.10
<P>This study was done to evaluate the stemness of human mesenchymal stem cells (hMSCs) derived from placenta according to the development stage and to compare the results to those from adult bone marrow (BM). Based on the source of hMSCs, three groups were defined: group I included term placentas, group II included first-trimester placentas, and group III included adult BM samples. The stemness was evaluated by the proliferation capacity, immunophenotypic expression, mesoderm differentiation, expression of pluripotency markers including telomerase activity. The cumulative population doubling, indicating the proliferation capacity, was significantly higher in group II (<I>P</I><0.001, 31.7±5.8 vs. 15.7±6.2 with group I, 9.2±4.9 with group III). The pattern of immunophenotypic expression and mesoderm differentiation into adipocytes and osteocytes were similar in all three groups. The expression of pluripotency markers including ALP, SSEA-4, TRA-1-60, TRA-1-81, Oct-4, and telomerase were strongly positive in group II, but very faint positive in the other groups. In conclusions, hMSCs from placentas have different characteristics according to their developmental stage and express mesenchymal stemness potentials similar to those from adult human BMs.</P>
Hyun-Min Ahn,Young-Ha Kwon,Nak-Jin Seong,Kyu-Jeong Choi,Chi-Sun Hwang,Sung-Min Yoon 대한금속·재료학회 2022 ELECTRONIC MATERIALS LETTERS Vol.18 No.3
The effect of two strategic approaches, such as modification of active layer geometry and control of active channel composition,were investigated to improve the on/off ratio (ION/IOFF) and field-effect mobility (μFE) of mesa-shaped nanoscalevertical-channel thin-film-transistor (VTFT). The SiO2spacer was deposited by using plasma-enhanced chemical vapordeposition and patterned via plasma etching process with Ar/CF4 gas mixtures to form a vertical sidewall, correspondingto a channel length of 170 nm. The gate-stack structures including an In–Ga–Zn–O (IGZO) active layer were depositedby atomic layer deposition with a complete conformality along the spacer sidewall. The ION/IOFF of the IGZO VTFT wassignificantly enhanced from 6.7 × 103to 2.1 × 109by lowering the off-state current when the layout geometry of active layerwas properly designed to eliminate the uncontrolled current path between the vertically separated source and drain (S/D)electrodes. Furthermore, the μFE was improved from 0.3 to 2.2 cm2/Vs by enhancing the IONwhen the In/Ga ratio increasedto 1.4 by controlling the In contents within the IGZO active channel. The device also showed robust stabilities under positive/negative gate-bias stresses at 2 MV/cm for 104s. However, still low a μFE was suggested to originate from two detrimentalissues of back-channel effects on spacer sidewall and contact resistance between the channel and S/D electrodes. Alternatively,it was confirmed that the increase in indium contents within the IGZO channel could be a useful way to reduce the contactresistance between the channel and S/D electrodes.
Frontal Assessment Battery to Evaluate Frontal Lobe Dysfunction in ALS Patients
Ahn, Suk-Won,Kim, Su-Hyun,Kim, Jee-Eun,Kim, Sung-Min,Kim, Seung Hyun,Sung, Jung-Joon,Lee, Kwang-Woo,Hong, Yoon-Ho Cambridge University Press 2011 The Canadian journal of neurological sciences Vol.38 No.2
<B>Background:</B><P>Assessment of frontal lobe impairment in amyotrophic lateral sclerosis (ALS) is a matter of great importance, since it often causes ALS patients to decrease medication and nursing compliance, thus shortening their survival time.</P><B>Methods:</B><P>The frontal assessment battery (FAB) is a short and rapid method for assessing frontal executive functions. We investigated the applicability of the FAB as a screening method for assessing cognitive impairments in 61 ALS patients. Depending on the results of the FAB, we classified patients into two subgroups: FAB-normal and FAB-abnormal. We then performed additional evaluations of cognitive function using the Korean version of the mini-mental state examination (K-MMSE), a verbal fluency test (COWAT), and a neuropsychiatric inventory (NPI). Results of these tests were compared between the two groups using Mann-Whitney U-tests, and Spearman correlation analyses were used to investigate the relationships between FAB score and disease duration and severity.</P><B>Results:</B><P>Of the 61 sporadic ALS patients included in this study, 14 were classified as FAB-abnormal and 47 were classified as FAB-normal. The FAB-normal and FAB-abnormal patients performed significantly differently in all domains of the COWAT. There was no difference in behavioral disturbance, as assessed by the NPI, between the two groups. The FAB scores were found to significantly correlate with both disease duration and severity.</P><B>Conclusions:</B><P>The FAB shows promise as a method of screening for frontal lobe dysfunction in ALS, as it is not only quick and easy, but also reliable. Additional studies should examine how FAB performance changes as ALS progresses.</P>
Ahn, Sung Il,OHk, Chang Woo,Kim, Jae Hyun,Zin, Wang-Cheol Wiley Subscription Services, Inc., A Wiley Company 2009 Journal of polymer science Part B, Polymer physics Vol.47 No.22
<P>The continuous-multilayer model introduced in our previous study for the T<SUB>g</SUB> behavior of thin films is adapted to nanocomposite systems. T<SUB>g</SUB> enhancement in both thin films and nanocomposites with attractive interfacial interactions can be explained by the same model. Various shapes of nanoparticles are proposed to rationalize the adaptation of the one-dimensional model for the T<SUB>g</SUB> behavior of thin film to three-dimensional system such as nanocomposite. The tendency of predicted T<SUB>g</SUB> enhancements in poly(methyl methacrylate) and P2VP nanocomposites with silica particles are qualitatively fit to experimental data in literatures. For the further quantitative fitting, the model is partially modified with the consideration for other factors affecting T<SUB>g</SUB> deviation in nanocomposite. © 2009 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 47: 2281–2287, 2009</P>
The Expression Profile and Function of Satb2 in Zebrafish Embryonic Development
Ahn, Hyun-Jong,Park, Yoo-Jin,Kim, Su-Hyun,Park, Hae-Chul,Seo, Su-Kyoung,Yeo, Sang-Yeob,Geum, Dong-Ho Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.30 No.4
The present study shows the expression profile and function of the homeobox gene, satb2 during zebrafish embryonic development. Satb2 was ubiquitously expressed from the 1 cell stage to the 10-somite stage in zebrafish embryos. Satb2 showed stage-specific expression profiles such as in the pronephric duct at 24 hpf, the branchial arches at 36 hpf, and the ganglion cell layer of the retina and fins at 48 hpf. Additionally, satb2 knockdown embryos were arrested at 50-60% epiboly, and transplantation experiments with satb2 knockdown cells showed migration defects. Interestingly, satb2 knockdown cells also exhibited down-regulation of dynamin II and VAMP4, which are involved in exocytosis and endocytosis, respectively. Furthermore, satb2 knockdown cells have a disorganized actin distribution and an underdeveloped external yolk syncytial layer, both of which are involved in epiboly. These results suggest that satb2 has a functional role in epiboly. This role may potentially be the regulation of endo-exocytic vesicle transport-dependent cell migration and/or the regulation of the development of the yolk syncytial layer.
Sang Hyub Lee,Jae Sung Ahn,Joo Won Lim,Seung Hyun Jeon,Hyung-Lae Lee,Sung-Goo Chang 대한비뇨기종양학회 2010 대한비뇨기종양학회지 Vol.8 No.3
Purpose: We analyzed the differences between the patients who were diagnosed with prostate cancer after a previous negative biopsy and the patients who were diagnosed as nodular hyperplasia by a repeat biopsy to find out the difference between the cancer group and the negative group and to identify the useful predictors of prostate cancer on repeat biopsies. Materials and Methods: 43 patients received a repeat TRUS-guided biopsy of the prostate due to the persistent elevation of PSA after a negative initial prostate biopsy. All of the patients were classified either as cancer group or negative group. We reviewed their TRUS findings, PSAV, PSAD and %fPSA. Statistical analysis was performed using the Mann-Whitney U test, Fischer’s exact test and ROC curve. Results: Prostate cancer was detected in 7 of the 43 patients (16.3%) on repeat biopsy. PSAD of prostate cancer group was higher than that of the negative biopsy group (0.38±0.16 vs. 0.21±0.13). %fPSA level of the prostate cancer group was lower than that of the negative group (9.61±2.65 vs. 19.93±10.71). However, there was no difference within PSAV statistically and no relation between the hypoechoic lesion on TRUS and the prostate cancer proven by repeat biopsy. By ROC curve, only PSAD had a significant role as a screening test of repeat prostate biopsy. Conclusions: Based on our study, only PSAD is an effective test for screening prostate cancer on repeat prostate biopsy. We suggest that the ideal cutoff value of PSAD is 0.20 instead of 0.15.