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      • SCOPUSKCI등재

        신 이식 후 Parvovirus B19 감염에 의한 적혈구무형성증 1 예

        이정익(Jeong Ik Lee),강태영(Tae Young Kang),조한표(Han Pyo Cho),윤창옥(Chang Ok Yoon),정청일(Chung Il Jung),이숙진(Sook Jin Lee),강문수(Mun Su Kang),이창화(Chang Hwa Lee),강경원(Kyoung Won Kahng),박찬현(Chan Hyun Park),강종명(Chong M 대한신장학회 2001 Kidney Research and Clinical Practice Vol.20 No.4

        Parvovirus B19 infection is known to cause chronic anemia in immunocompromised hosts, including organ transplant recipients. We report a case of pure red cell aplasia caused by parvovirus B19 in renal transplants. The patient was 16-year-old male who was diagnosed as chronic renal failure 7 years ago and had been on hemodialysis twice a week. He got renal transplantation in June 1999. But anemia was not improved in first postoperative period. On admission hemoglobin was 43.0 g/L, hematocrit was 12.7%. The bone marrow biopsy revealed severe erythroid hypoplasia with giant pronormoblasts. The pronormoblasts showed prominent intranuclear inclusions, characteristic of parvovirus B19 infection. The parvovirus H19 PCR and anti-parvovirus B19 IgM were positive. The patient was treated with intravenous immunoglobulin and then reticulocyte count was in- creased 5 days later. Hemoglobin level restored to 104 g/L two months later.

      • 심근경색후 발생한 좌심실 가성동맥류 환자 1예

        조한표,이숙진,신대희,최성일,한 호,이 상,김순길,김경수,임헌길,김정현,이방헌,이정균 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

        Left ventricular pseudoaneurysm is defined as a rupture of the myocardium that is contained by pericardial adhesion or the epicardial wall. The etiology of pseudoaneurysm are mainly transmural myocardial infarction, various type of cardiac surgery, blunt or penetrating chest trauma, infection (endocarditis, myocarditis, tuberculosis, syphilis). Although LV pseudoaneurysm is clinically uncommon, diagnosis is difficult and rupture often leads to death. Therefore, a surgical repair is necessary in most cases of left ventricular pseudoaneurysm. It is important to have a high clinical index of suspicion, because the symptoms, signs, electrocardiographic abnormalities and radiographic findings seen in LV psuedoaneurysm can be indistinguishable from those in patients with coronary disease alone. We report a case of 64-year-old male with coronary artery disease of 3 vessel and symptomatic left ventricular pseudoaneurysm after myocardial infarction.

      • 수술 전 심장기능 평가에 있어 심근관류 SPECT의 유용성

        신대희,조한표,최성일,이숙진,이 상,이재웅,김경수,김순길,김정현,임헌길,이방헌,이정균,최윤영 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

        Background/Aims: The preoperative cardiac evaluation is important to predict perioperative cardiac event in patients who planned for non-cardiac operation. However, the usefulness of cardiac SPECT and/or evaluation of patient with clinical criteria is not clear. Therefore we evaluate the prognostic value of cardiac SPECT in surgical patients. And also compare the result of clinical risk stratification using the ACC/AHA guidelines with those of cardiac SPECT. Methods: 75 patients(M:F=31:44, 62.8±9.2 years), who have chest pain, EKG abnormality or history of ischemic heart disease were enrolled to the study. According to the result of cardiac SPECT, they were divided to 3 groups: normal perfusion(n=51), reversible perfusion defect(n=31), irreversible perfusion defect(n=3). Also we divided 3 groups according to clinical predictors of the ACC/AHA guidelines: minor risk group(n=51), intermediate risk group(n=21), and major risk group(n=3). I compare predictive power of perioperative cardiac event between cardiac SPECT and clinical predictors of the ACC/AHA guidelines. Results: Cardiac event occurred in 9.2% of patient. Prevalence of cardiac event in reversible cardiac perfusion group(19.0%) and irreversible cardiac perfusion group(33.3%) was higher than normal group(3.8%)(p〈0.05). By clinical predictors according to the ACC/AHA guidelines, I could not predict the postoperative cardiac event. Conclusion: Cardiac SPECT is more useful than clinical predictors according to the ACC/AHA guidelines in preoperative cardiac evaluation in patients with chest pain, EKG abnormality or history of ischemic heart disease.

      • On some properties of Fuzzy congruence relations

        Sung, Yeoul Ouk,Cho, Han Pyo 公州大學校 基礎科學硏究所 1999 自然科學硏究 Vol.8 No.-

        본 논문에서는 반군에서의 크리스합동관계와 퍼지합동관계에 관한 하반근사 및 상반근사의 일부 성질을 조사하였고, 또한 퍼지합동관계와 fuzzy difunctional relation사이의 관계를 특성화하였다. In this thesis, we investigate some properties of the lower and upper approximation with respect to the congruences and the fuzzy congruences on a Semigroup. Also, we study a relation between fuzzy congruences and fuzzy difunctional relations.

      • ^201Thallium SPECT에서 ^201Thallium 제거율과 좌심실 이완 기능과의 관련성

        최성일,김정현,신대희,조한표,이숙진,이 상,이재웅,김경수,김순길,임헌길,이방헌,이정균,최윤영 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.1

        배경/목적: 관동맥 협착에 의한 관동맥혈류예비능의 감소는 급사의 위험 인자로 잘 알려져 있다. 최근에 정상 관동맥에서도 이완기 장애에 의한 관동맥 혈류 장애의 위험성이 있다는 보고가 있는 후, 좌심실이완 기능 장애의 임상적인 중요성을 찾으려는 노력이 있다. 한편, 201^Thallium 심근 관류 SPECT은 관동맥질환의 진단에 유용하지만, 아직까지 좌심실의 이완 기능을 평가하는 방법은 알려져 있지 않고 있다. 그래서, 201^Thallium 심근 관류 SPECT에서 201^Thallim의 제거율 감소가 이완기 장애 (diastolic dysfunction)를 평가할 수 있는 지표로 사용될 수 있는지 알아보고자 하였다. 방법: 심장초음파 검사에서 구혈률이 정상이고 판막질환과 좌심실비대가 없는 135명의 환자에서 201^Thallium 심근 관류 spect를 시행하였다. 도플러심초음파를 이용한 승모판의 inflow study로 이완 장애군과 정상군으로 구분하였는데, 이완장애군은 E/A비가 1미만이거나, 이완시간이 240ms이상인 경우로 정의하였고, 정상 대조군은 E/A비가 1이상 2미만이고 이완시간이 160ms이상 240ms 미만인 경우로 정의하였다. 결과: 좌심실 이완기 장애시 201^Thallium의 제거율은 38.1%이였고, 정상군에서는 46.6%로 이완 장애군에서 의미있게 낮은 결과를 나타냈다. 결론: 201^Thallium 심근 관류 SPECT에서 201^Thallium의 제거율은 좌심실의 이완기 장애를 나타내는 유용한 지표로 사료된다. Background and Objectives : Reduced coronary flow reserve due to coronary artery stenosis is well known as a risk factor for sudden cardiac death. Recently, as it has been also reported that reduced coronary flow reserve caused by diastolic coronary flow disturbance in normal coronary angiogram is at fisk, much effort is in progression to study clinical significance of left ventricular diastolic dysfunction. By the way, 201^Thallium cardiac perfusion SPECT is useful for the detection of coronary artery disease, but to date, hasn't been yet known for assessment method of left ventricular diastolic dysfunction. Therefore, the aim of this study is to investigate whether the 201^Thallium washout rate in 201^Thallium cardiac perfusion SPECT is considered as a novel marker of evaluation of left ventricular diastolic function. Materials and Method : We selected 135 persons who had heart funcion with normal ejection fraction and normal valvular state and no concentric left ventricular hypertrophy on echocardiography examination, then performed 201^Thallium cardiac perfusion SPECT. They were grouped as normal group and abnormal relaxation group by the definition of echocardiographic mitral valve inflow study, that is, abnormal relaxation is defined as reversed E/A ratio or prolonged deceleration time and normal diastolic function is defined as 1≤E/A ratio〈2 and 160ms≤ deceleration time 〈 240ms. Results : 201^Thallium washout rate of left ventricular diastolic dysfunction group (abnormal relaxation group) in 201^Thallium cardiac SPECT is significantly lower than normal group(38.1%; 46.6%, p〈0.01). Conclusion : 201^Thallium washout rate in 201^Thallium cardiac SPECT is considered as a useful marker of evaluation of left ventricular diastolic function.

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