http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
혈구탐식성 조직구증식증 환아에서 동종골수이식 치험 1례
조빈,정대철,김학기 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1
Hemophagocytic lymphohistiocytosis (HLH) is rare disease characterized by fever, hepatos-plenomegaly and cytopenia. The histological findings consist of a nonmalignant accumulation of histiocytes in the reticuloendothelial system. The natural course of HLH is usually fatal. Chemotherapy, including etoposide (VP-16) combined with steroid has markedly prolonged the survival of affected children, but has not resulted in a cure. As a new therapeutic strategy, bone marrow transplantation has been reported in children with HLH with promising results. Here we present the first case of allogeneic bone marrow transplantation for HLH in Korea with successful outcome.
Fanconi 빈혈 환아에서 전처치로서 저용량의 cyclophosphamide와 총림프절 방사선 조사를 시행한 동종 골수이식 치험 1례
조빈,정대철,김학기,국훈,황태주 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1
Fanconi anemia is a genetic disorder associated with diverse congenital abnormalities, progressive bone marrow failure, and increased risk of malignancies. Fanconi anemia cells show a high level of chromosomal breakage, both spontaneously or when induced by cross-linking agents such as mitomycin C, nitrogen mustard, diepoxybutane or photoactivated psorarens. Bone marrow transplantation is an effective therapy for Fanconi anemia. Because Fanconi anemia patients may have increased sensitivity to cyclophosphamide and radiation in doses commonly used for pretransplant conditioning, most centers use lower doses to decrease transplantrelated mortality. In this report we describe a case of allogeneic matched sibling donor bone marrow transplantation in a 14-year-old boy with Fanconi anemia, using a low-dose cyclophosphamide and TNI as a conditioning regimen.
동종골수이식 후 세포유전학적으로 재발된 Philadelphia 염색체-양성 급성 림프구성 백혈병 환아에서 공여자 백혈구 주입에 의해 성공적으로 세포유전학적 재관해를 유도한 1례
조빈,정낙균,정대철,김학기 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.1
화확요법의 발달과 고위험군에서의 성공적인 조혈모세포 이식으로 소아 급성림프구성 백혈별의 예후는 현저히 개선되었으나, Ph^(+)ALL의 경우는 예후가 좋지 않다. Ph^(+)ALL의 치료로서 현재 알려진 가장 효과적인 방법은 조혈모세포 이식이나 이식후의 재발율이 매우 높은 실정이다. 최근 골수이식 후 재발한 급성 백혈병에 있어서 공여자 림프구를 주입함으로서 이식편대백혈병 효과를 유발하려는 시도들이 있다. 저자들은 국내에서는 처음으로 골수이식 직후 RT-PCR 검사로 세포유적학적 재발이 증명된 Ph^(+)ALL 환아에서 혈액학적으로 재발하기 전에 공여 백혈구를 주입하여 이식편대숙주병을 유발함으로서 성공적으로 세포유전학적 재관해를 유도한 1례를 보고한다. Donor laukocyte infusion(DLI) was carried out on a 10-year-old boy with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph^(+)ALL) who received allogeneic bone marrow transplantation from an HLA-identical sibling. In Korea, this is the first report of DLI use before the onset of hematological relapse monitored by the results of reverse transcriptase-polymerase chain reaction (RT-PCR). Life threatening grade Ⅲ GVHD was appeared after the second DLI and it was successfully controlled with methylprednisolone. This patient has been in complete remission for 133 days after BMT, suggesting this alternative treatment is promising for Ph+ALL with positive RT-PCR following BMT.
조빈,엄영욱 한국중국문화학회 2020 中國學論叢 Vol.0 No.66
After the "spatial turn" space narrative has become the hottest "doctrine". However, the current space narrative to a bottleneck stage, a variety of reasons. "Spatial turn" of the modern trend of thought has a unshirkable responsibility. Has been, scholars turned to "empty" the complex relationship between space narrative and, type of narrative space narrative theory problem also not too clear by the noun, the term textual research, narrative of space studies provide some of the necessary theoretical support, to promote the healthy development of the research on novel narrative space. 在"空间转向"之后,空间叙事成为最热的"理论"。 然而,目前的空间叙事进入瓶颈期,原因多种多样。 现代思潮的"空间转向"有着不可推卸的责任。 学者们转向"空"了空间叙事与空间叙事理论问题的复杂关系,类型叙事空间叙事理论问题也不为名词所太清楚,空间研究这一术语提供了必要的理论支持,以促进新奇叙事研究的健康发展。
曹斌 동양고전학회 2015 東洋古典硏究 Vol.0 No.58
The popular age of Bronze Zhi across the two bronze prosperous stages of late Shang and prior period of Western Zhou, which is a kind of very important bronze drinking vessels of the Shang and Western Zhou Dynasties. In view of the importance of bronze Zhi for relevant academic issues discussed, this paper, based on a comprehensive collection of excavated and handed down bronze Zhi, to classify the type of bronze Zhi with archaeological typology method, summarize the development evolution, periodize bronze Zhi according to shape, ornamentation, combination and inscriptions, and judge the absolute date of each phrase and sub-phrase according to typical units and coexistence pottery. In this paper, the earliest slender-body Zhi appear in Ji'nan Daxinzhuang tombs of the Yin RuinsⅠculture, the earliest bold Zhi find in Anyang tombs of the Yin Ruins Ⅱ culture, Zhi achieve the bloom period in Yin Ruins Ⅳ culture after the development of the Yin Ruins Ⅲ culture, which sharp increase the amount and shapes, and expand distribution range beyond the region of Shang Dynasty ruled. Zhi reach a new boom period in the early Western Zhou Dynasty, the distribution range extend to the new occupied area of Western Zhou Dynasty in addition to the amount significantly more than Yin Ruins Ⅳ culture. And then, Zhi change from consolidation to decline in the early sub-phase of the mid Western Zhou Dynasty, which obviously reduce the amount and make rough, and completely vanish in the late sub-phase of the mid Western Zhou Dynasty.