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Benign and malignant tumor of epidermis
정보영 ( Bo Young Chung ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
Following topics will be discussed in this lecture. 1. Benign epithelial tumors - Seborrheic keratosis - Epidermal nevus - Epidermal nevus syndrome - Epidermoid cyst - Millium - Dermoid cyst 2. Epithelial precancerous lesions - Actinic keratosis - Viral-associated epithelial precancerous lesions - Bowen disease 3. Malignant epithelial tumors - Basal cell carcinoma - Squamous cell carcinoma
정보영 ( Bo Young Chung ),조수익 ( Soo Ick Cho ),안인수 ( In Su Ahn ),이희봉 ( Hee Bong Lee ),김혜원 ( Hye One Kim ),김광호 ( Kwang Ho Kim ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.3
Nodular hidradenocarcinoma was first reported as a clear-cell papillary carcinoma by Liu et al. in 1949. With a potential for uncontrollable local recurrence, it tends to metastasize and often causes death. We report a case of a 68-year-old man with nodular hidradenocarcinoma on the left preauricular area. Histopathology of the tumor showed a multilobulated intradermal mass. In the tumor nodule, there were many cystic spaces of various sizes, resulting from tumor necrosis. The tumor consisted of large, atypical, polygonal cells with eosinophilic cytoplasm, and clear cells with clear cytoplasm. Numerous mitoses were evident. We obtained positive results from an immunohistochemical study with antibodies to cytokeratins, epithelial membrane antigen, and PAS. The patient was treated with a wide local excision. However, we observed a recurrence one month later and performed a wide excision and local skin flap. There has been no evidence of recurrence or metastasis for six months after the second excision. (Korean J Dermatol 2011;49(3):250∼254)
Benign and malignant tumors of the skin
정보영 ( Bo Young Chung ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
This lecture covers following topics. 1. Epithelial precancerous lesions - Actinic keratosis - Bowen`s disease - Bowenoid papulosis - Erythroplasia of Queyrat 2. Benign epithelial tumors - Seborrheic keratosis - Epidermal nevus - Epidermal nevus syndrome - Epidermal cyst - Milium - Dermoid cyst - Trichoepithelioma - Pilomatricoma 3. Basal cell carcinoma 4. Squamous cell carcinoma 5. Keratoacanthoma 6. Kaposi`s sarcoma 7. Merkel cell carcinoma 8. Paget`s disease 9. Melanoma
Differential diagnosis and pathophysiology of red face: Focusing on the skin barrier
정보영 ( Bo Young Chung ) 한국피부장벽학회 2022 한국피부장벽학회지 Vol.24 No.1
Facial erythema (the red face) is a straightforward clinical finding; however, a red face does not represent a single cutaneous entity. In other words, in clinical practice, dermatologists do not encounter only one type of facial erythema but rather a number of different shades of red. Diagnosis is based on different data: date and mode of appearance, characteristics of the erythema, functional signs, and associated systemic manifestations. A case of red face can have an infectious origin, caused by vascular, congenital, or acquired lesions, or be caused by photodermatosis, or be the main location of inflammatory dermatosis or collagenosis, but depending on the clinical context, many other diagnoses can be suggested. This lecture presents the clinical spectrum of facial erythemas and addresses the question of what lies beneath a red face by discussing the key pathophysiologic characteristics focusing on skin barrier.
식육알레르기 발생 경향 및 잠재적 우육알레르겐에 관한 연구
정보영,김동엽,정현채,한기동,Jeong, Bo-Young,Kim, Dong-Yeop,Fan, Jiang Ping,Chung, Hyun-Chae,Han, Gi-Dong 한국축산식품학회 2009 한국축산식품학회지 Vol.29 No.2
The prevalence of food allergies was investigated using questionnaires with 300 subjects whose ages ranged from 19 to 24 years old and the causative food allergens was analyzed using immunological analysis with serum of the subjects who answered that they have/had food allergy. The questionnaire showed that 11.33% of subjects have/had experience of food hypersensitivity, where the main causative foods were fish, beef, chicken, milk, egg, and pork in order. The meat allergy shared 4.65% (2.33% for beef, 1.66% for chicken, 0.66% for pork) in the prevalence of food allergies. The causative beef allergens were investigated with the serum of 6 subjects who have had beef allergy. Western blots were carried out with the serum of P6 subject who showed a positive reaction to beef extract in ELISA. The two specific bands were detected in beef extract on the PVDF membrane, and no band was detected in extracts of pork and chicken. A calculation of the distance of migration by SDS-PAGE enabled the molecular masses of the two bands to be estimated as 67kDa and 31kDa, respectively. The 67kDa was revealed as bovine serum albumin (BSA) which is one of the important beef allergens as reported previously though an analysis of the N-terminal amino acid sequence. However we could not identify the sequence of 31kDa, probably because they comprised several subunits and were modified proteins such as glycoprotein that were unlikely to be easily degraded by the Edman method. The 31kDa band were dyed with the PAS (periodic acid-schiff reagent), suggesting that it might be a glycoprotein. These results suggested that the 31kDa might be considered as a novel potential beef allergen which is not reported previously, although further studies are needed.
정민재 ( Min Je Jung ),김혜원 ( Hye One Kim ),강석영 ( Seo Young Kang ),김진철 ( Jin Cheol Kim ),정보영 ( Bo Young Chung ),박천욱 ( Chun Woo Park ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.3
Verrucous carcinoma is a rare, low-grade, well-differentiated variant of squamous cell carcinoma. It occurs mainly on the soles, but has also been reported in other locations, including the buttocks, hand, anus, and genitalia. A 38-year-old woman presented with an asymptomatic skin lesion of the nipple. She first noticed the lesion three months prior. A solitary, cauliflower-shaped, black polypoid mass was observed on her right nipple. Histopathological examination revealed a superficial lesion resembling verruca vulgaris. It was composed of relatively well-differentiated cells with severe epidermal proliferation, and some tumor cells were observed in the dermis. The final diagnosis was verrucous carcinoma. Complete excision of all the lesions was performed. The patient had no recurrence. We report an interesting case of verrucous carcinoma that occurred at a relatively rare site; only one previous report of verrucous carcinoma associated with the breast or nipple was found. (Korean J Dermatol 2021;59(3):234∼236)
정보영 ( Bo Young Chung ),조수익 ( Soo Ick Cho ),안인수 ( In Su Ahn ),김혜원 ( Hye One Kim ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ) 대한피부과학회 2011 大韓皮膚科學會誌 Vol.49 No.8
Eccrine poroma is a benign neoplasm that originates from an eccrine sweat duct. Although it is most commonly found on the soles of the feet, it has also been unusually observed on many other areas of the skin, such as the nose, neck, chest, and scalp. We report two cases of eccrine poroma occurring on the scalp, which is an unusual location. (Korean J Dermatol 2011;49(8):768∼771)