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장동원,박철훈,조병헌,조규철 中央醫學社 1976 中央醫學 Vol.30 No.2
It is generally known that Akebiae Lignum, Pachymae Fungus, Plantaginis Semen and Polygoni aviculareae Herba have been conventionally used as the diuretics by the Chinese medicinal herb doctors and a number of laymen. However, their pharmacological researches concerning the characteristics and active ingredients have not been fully conducted yet. The changes of urine volume and pH as well as urinary electrolytes (Na+, K+ and Cl-) were measured at 15 minutes interval for 2 hours after the admini?stration of ALWE (Akebiae Lignum water extract), PFEE (Pachymae Fungus ethyl alcohol extract), PSEE(Plantaginis Semen ethyl alcohol extract) and PHEE (Polygoni aviculareae Herba ethyl alcohol extract) in rabbits. The results were as follows: 1) Urine volume as well as excretion rate of urinary electrolytes (Na+, K+ and Cl-) in ALWE-treated group was significantly higher than that of saline-treated control group. Urinary pH of ALWE-treated group was lower than that of saline-treated control group. 2) No significant changes of urine volume, pH and urinary electrolytes Na+, K+ and Cl-) excretion were observed in the PFEE-treated group, compared with those of saline-treated control group throughout the experiments. 3) Urinary pH of PSEE-treated group was significantly lower than that of saline-treated control group. No significant changes of urine volume and urinary electrolytes (Na+, K+ and Cl-) excretion were observed in PSEE-treated group, compared with those of saline-treated control group. 4) Cl- excretion of PHEE-treated group was significantly higher than that of saline-treated control group. No significant changes of urine volume, pH and
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장동원,송석재,Jang, Dong-Won,Song, Seok-Jae 한국전자통신연구원 1993 전자통신동향분석 Vol.8 No.1
본 고는 전화망에서 가입자가 적정 수준의 서비스를 받고 있는지의 여부를 수치로 나타내서, 이 수치가 항상 가입자에게 만족스런 상태로 서비스가 제공되고 있음을 나타내도록 하는 기준값을 얻기 위한 방법을 제시하였다. 이를 위하여 먼저 국내의 전화망의 특성을 파악하고, 이에 따른 품질척도에 대한 실측이 수행되었으며, 또한 가입자가 느끼는 서비스에 대한 만족도를 조사하였다. 측정된 각각의 품질척도와 이에 대한 가입자의 만족도를 바탕으로 다이얼톤지연, 다이얼후지연, 그리고 블로킹률에 대한 기준값을 구하였다.
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장동원,조평동 한국정보통신학회 2001 한국정보통신학회논문지 Vol.5 No.6
본 고에서는 웹 서버 팜(farm)의 성능을 향상시키기 위해서 사용되는 로드 발란서(load balancer)의 성능을 측정하고 분석하였다. 로드 발란서는 입력되는 트래픽을 서버 팜의 각 서버에 고르게 분산시켜서 클라이언트의 접속 요구를 최대한 수용해서 전체적인 서비스 품질을 향상시킨다. 본 고에서는 로드 발란서가 초당 최대 수용할 수 있는 접속 요구를 측정하고 이때 로드 발란싱(load balancing)이 서버 팜의 각 서버로 고르게 이루어 졌는지 측정한다. In this paper, we tested and analysed the performance of the load balancer which advances the performance of web server farm. Load balancer distributes the traffic that is inputting from internet and accepts client's connection requests to its maximum capacity. Then we test the maximum connection requests per second that load balancer processed and the load balancing that established with the load balancer.
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실 해상모형시험을 이용한 고속 활주정의 선형시험기법 기초연구
장동원,박충환,진송한 한국항해항만학회 2010 한국항해항만학회지 Vol.34 No.8
High speed marine vehicle, such as semi-planing, planing craft have been developed recently. These ships paid attention to the resistance characteristics, especially in high speed region. Model test method is divided to two equipment greatly, first 'Towing tank', second 'C.W.C.'. It is difficult to estimate a resistance characteristics for high speed boat. because these are made for low speed ship. This paper suggests a new model test method and system. This is real sea model test and it's comprised of eight part. Firstly, This method is tested at C.W.C that is possible to using in real sea model tes using low speed boat modelt. And then, Real sea model test and CFD calculation are performed and compared with tow way used high speed boat model. It can be a good way to estimate a performance for high speed boat. 현재 모형선을 이용한 선형성능 검증설비는 예인수조와 회류수조 두설비가 주로 이용된다. 이들 설비는 주로 저속 대형선박을 위해 기법들로 소형 고속어선 및 고속레저선박의 저항성능 평가를 수행하기에 전차의 속도와 유속이 목표속도에 미치지 못해 어려움이 존재한다. 따라서 고속 선박의 저항성능 평가를 위해 새로운 기법 정립 연구가 필요하다. 이에 고속선의 저항성능 시험을 위해 실제 해상에서 선박을 이용한 모형시험을 고안하고 측정시스템을 구성하였다. 시스템구성은 총 8개의 파트로 구성되어 있으며, 시스템 검증을 위해 C.W.C에서 저속선의 모형을 이용하여 시험을 수행하여 시스템 적용 가능성을 검증하였다. 또한 실제 해상에서 고속선 모형선을 이용하여 시험을 수행하였으며, 이 결과를 CFD해석 결과와 비교하여 실해상 모형시험 방법의 가능성을 확인 하였다.
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Acetazolamide 의 Carbonic Anhydrase 활성 억제 작용에 대한 Testosterone 의 영향
장동원,이상복,조규철,Chang, Dong-Won,Lee, Sang-Bok,Cho, Kyu-Chul 대한약리학회 1975 대한약리학잡지 Vol.11 No.2
This study was carried out to observe the effect of testosterone on carbonic anhydrase inhibiting action of acetazolamide. Carbonic anhydrase activities in the kidneys of mice were measured by Philpot and Philpot method(1936) at 30, 90 and 150 minutes after intravenous administration of saline(0.5 ml/10 g) or acetazolamide (0.25 mg/10 g) in mice pretreated with testosterone (0.1 mg/10 g). The changes in volume and pH of urine as well as those in urinary electrolytes, such as $Na^+,\;K^+\;and\;Cl^-$ were measured at 15 minutes interval for 150 minutes in the rabbit pretreated with double administrations of testosterone(10 mg/kg), 1 hour and 18 hours, prior to the administration of acetazolamide (10 mg/kg). The results were as follows: 1. Carbonic anhydrase activities in the kidneys of mice of testosterone-pretreated groups were significantly higher than those of acetazolamide-treated group at 30 minutes. No significant changes of carbonic anhydrase activities were observed in testosterone-pretreated groups compared with saline-treated groups. 2. Combined administrations of acetazolamide and testosterone exhibited higher carbonic anhydrase activity than those group of acetazolamide alone in the kidney of mice through observed period of 150 minutes. 3. There were no significant changes in the excretion rate of urine and urinary electrolytes in the group of rabbits with testosterone administerone alone. Urine volume as well as $Na^+\;and\;Cl^-$ excretion rates in the combined treated group of acetazolamide and testosterone were significantly lower than that of acetazolamide group throughout experimental period except 15 minutes after drug administration at the time transient increase was shown. 4. Generally lower $K^+$ excretion rate was observed in the combined treated group of acetazolamide and testosterone compared with the single acetazolamide-treated group and the testosterone-pretreated group shows lowest excretion rate of potassium.
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