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      • KCI등재

        인삼패독산(人蔘敗毒散) 및 발효인삼패독산의 급성독성 연구

        임가영,황윤환,이지혜,오유창,조원경,마진열,Im, Ga-Young,Hwang, Yoon-Hwan,Lee, Ji-Hye,Oh, You-Chang,Cho, Won-Kyung,Ma, Jin-Yeul 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.3

        Objective : This study was carried out to investigate the acute toxicity and safety of Insampaedok-san and Fermented Insampaedok-san. Methods : SPF ICR male and female mice were administered orally with Insampaedok-san and Fermented Insampaedok-san. of 0(control group), 1,250, 2,500 and 5,000 mg/kg. After single administration, we daily examined number of deaths, clinical signs, gross findings and changes of body weight for 14 days. Hematological parameters and isolated organ weights were determined after 14 days of administration. Results : No dead animal and no significant changes of body weights were found during experimental period. In addition, no differences were found between control and all of treated groups in clinical signs, organ weights, hematology, and other findings. Conclusions : Insampaedok-san and Fermented Insampaedok-san. did not show any toxic effects and oral $LD_{50}$ values of the extracts was over 5,000 mg/kg in ICR mice.

      • KCI등재

        중학생의 가족응집력, 분노표현 및 인터넷 사용

        임가영 ( Ga Young Im ),강인순 ( In Soon Kang ),정희진 ( Hee Jin Jeong ) 부산대학교 간호과학연구소 2011 글로벌 건강과 간호 Vol.1 No.1

        Purpose: The purpose of this study was to identify the impact of family cohesion and anger level, anger expression mode on internet addiction of middle school student. Methods: The subjects of this study were 924 middle school students. The data were collected by structured questionnaire from December 5 to December25 of 2007 and analyzed by SPSSNVIN 12.0 program, Results: Male Participants tended to be more addictive to internet than female, and the higher grade and longer they used internet, the severer they tended to be addicted to internet, The group with high anger lever showed high anger-in level and anger-out level, unsuitable anger expression, modes, and its mental health status was bad. The higher anger-in level and anger-out level group showed, the worse their mental health status was. For middle school student`s mental health, therefore, it is needed to provide programs which can decrease anger level and dissolve anger and educate middle school student to express anger at an acceptable level according to situation. Conclusion: Based on these findings, it is needed that enhancing communication between adolescents and their parents, particularly for male and those in the lower grades. Implication for social work practice and policy were discussed.

      • KCI등재

        증숙 및 습식분쇄 조건에 따른 인삼의 품질 특성

        임가영(Ga-Young Im),장세영(Se-Young Jang),정용진(Yong-Jin Jeong) 한국식품영양과학회 2010 한국식품영양과학회지 Vol.39 No.7

        본 연구에서는 인삼의 유용성분 강화 및 인삼 전근 활용을 위한 증숙 및 습식분쇄 조건을 조사하였다. 그 결과 무처리 (A), 95℃/3 hr(B) 및 121℃/15 min(C)의 증숙조건에 의해 각각의 당도는 7.7, 10.7 및 11.2°Brix, 갈색도 0.37, 1.97 및 1.50로 증숙구간에서 당도 및 갈색도가 높게 나타났다. 조사 포닌 함량은 7.19(A), 6.99(B) 및 8.83 ㎎/g(C)으로 C 조건에서 가장 높게 나타났다. 관능검사를 실시한 결과 C 조건에서 쓴맛 감소, 단맛 강도 및 전반적 기호도가 가장 높게 나타나 증숙처리 조건에서 관능적인 특성을 향상시킬 수 있었다. 가수량에 따른 습식분쇄 조건을 조사한 결과 가수량 300%에서 입자가 가장 작게 나타났다. 인삼의 습식분쇄조건은 분쇄 30분 및 3회에서 분쇄효율이 높았으며 평균입자크기는 67.66 ㎛로 미세화되었다. 분쇄시간 및 횟수에 따른 유효성분 함량은 큰 차이가 없었다. 이상의 결과 증숙처리(121℃/15 min) 및 습식분쇄는 인삼의 전근 활용 및 유효성분 강화에 효과적인 것으로 확인되었다. This study was carried out to investigate the steaming and wet grinding conditions to save effective compositions and to utilize whole roots of ginseng. The sweetness at the 3 different steaming conditions of non steaming group (A), 95℃/3 hr group (B) and 121℃/15 min group (C) resulted in 7.7, 10.7 and 11.2°Brix, and the browning intensity of 0.37, 1.97 and 1.50, respectively. The contents of crude saponin at the different steam heat treatments were 7.19 (A), 6.99 (B) and 8.83 ㎎/g (C). When sensory evaluation was conducted, the ginseng products processed at C condition showed the highest scores in the evaluation categories of bitter taste reduction, sweetness and overall acceptance. These results suggest that sensory characteristics of ginseng could be enhanced by the steam heat treatments. When the wet grinding with water addition volume to the steamed ginseng treated at 121℃ for 15 min was also investigated, the smallest particle size resulted from the water addition volume of 300%. The grinding efficiency of ginseng was found to be high at 30 min of grinding time and 3 times of grinding frequency with the mean particle size of 67.66 ㎛. The content of effective component did not show significant differences by grinding time and grinding frequency. Based on the results, the steam heat treatments (121℃/15 min) and wet grinding procedures were found to be effective in utilizing whole roots and saving the effective compositions of ginseng.

      • KCI등재

        4년근 인삼의 효소적 가수분해 조건에 따른 품질특성

        임가영(Ga-Young Im),마진열(Jin-Yeul Ma),김건우(Kun-Woo Kim),최진국(Jin-Kook Choi),강동균(Dong-Kyoon Kang),권태룡(Tae-Ryoung Kwon),장세영(Se-Young Jang),정용진(Yong-Jin Jeong) 한국식품영양과학회 2011 한국식품영양과학회지 Vol.40 No.2

        본 연구에서는 4년근 인삼의 활용도를 높이기 위하여 효소적 가수분해 조건에 따른 품질 특성을 조사하였다. 인삼은 증숙 후 분쇄하여 가수분해 효소제 A, B, C 및 D 4종에 처리에 따른 품질특성을 조사한 결과 pH 5.5~5.6, 당도 4.0~4.33으로 큰 차이가 없었다. 조사포닌 함량은 D 효소제에서 가장 높았으며, B, C 및 A 순으로 나타났다. D 효소제의 농도 0.3%(w/w)까지 조사포닌, 환원당 및 총당 함량이 증가하였으며 이후에는 농도에 따른 차이는 없었다. 가수분해시간이 경과함에 따라 유효성분이 증가하였으나 3시간 이후 큰 변화는 없었으며, 60℃로 처리하였을 때 조사포닌 함량이 높게 나타났다. 이상의 실험결과 D 효소제, 효소제 농도 0.3% (w/w)로 60℃에서 3시간의 조건이 가장 적합한 나타났으며 이때 환원당, 총당 및 조사포닌 함량은 각각 18.11, 36.21 및 4.23 ㎎/g으로 확인되었다. 따라서 효소적 가수분해 방법은 4년근 인삼의 유효성분 증가에 효과적으로 다양한 활용 방법이 기대되었다. This study investigated quality characteristics of 4 year-old ginseng by enzymatic hydrolysis conditions to increase utilization. Ginseng was ground after steaming and was each treated with hydrolase A, B, C and D. When quality characteristics by the enzymes were examined, no significant difference was observed with pH of 5.5~5.6 and the sugar content of 4.0~4.33. The crude saponin content was the highest in ginseng treated with D, followed by B, C and A. The crude saponin, the reducing sugar and the total sugar contents increased until 0.3% (w/w) concentration in enzyme D with no significant difference by its concentration. Although active ingredients increased with time passage of hydrolysis, no significant change was found after three hours and the crude saponin content was the highest when ginseng was treated at 60℃. From these results, optimum conditions for 4 year-old ginseng were 60℃ for 3 hours with 0.3% (w/w) enzyme D, and under these conditions the reducing sugar, the total sugar and the crude saponin contents recorded 18.11, 36.21 and 4.23 ㎎/g, respectively. Therefore, enzymatic hydrolysis was found to be effective in increasing active ingredients of 4 year-old ginseng with various usages expected.

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      • KCI등재

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