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      • KCI등재

        운동 스트레스와 면역반응

        이한,김완수,안응남,손태열,안의수 한국운동영양학회 1998 Physical Activity and Nutrition (Phys Act Nutr) Vol.2 No.2

        Immune functions are claimed to be affected by psychological stressors and physiological mechanism, which involves the close interaction between nervous system, endocrine system, and immune system. In particular, acute intensive exercise causes much larger changes in the concentration of circulating immune cells mid hormones than does psychological stress. Continuous exercises as physical stress are known to affect immune function through three specific pathways. In the first pathway, the secretion of ACTH is promoted by stimulating the HPA axis, and catecholamines secreted in adrenal medulla and glucocorticoirds secreted in adrenal cortex affect immune functions. In the second pathway, immune function are affected by increasing the level of ACTH, β-endorphin, growth hormone (GH), and prolactin through the interaction of nervous system and endocrine system. In the third pathway, immune functions are affected through direct influence of lymphoid organ or sympathetic nervous system Besides, immune functions may be affected by the immune parameters like cytoldnes and external environment. Previous researchers reported that continuous exercise with moderate intensity is an important factor in the change of immune response. Although recently a great number of researches have been carried out about the correlation of nervous system, endocrine system and immune system, their exact mechanism is yet to be worked out, requiring further researches in the future. It may not be an exaggeration to say that life in the modern world is life under stress. It is generally approved that one of the most efficient ways to resolve stress is exercise. However, since exercise itself can act as distress weakening immune functions, it is very important to carry out continuous researches to find out the influence of exercise on immune functions in the light of exercise immunology.

      • KCI등재

        요추간판 탈출증에 동반된 편측 족하수 환자 치험 2례 - 장비골근 침치료 중심으로

        이한,조재희,이효은,정호석,김은석,한경완,양동호,유인식,Lee, Han,Cho, Jae-Hee,Lee, Hyo-Eun,Jung, Ho-Suk,Kim, Eun-Seok,Han, Kyung-Wan,Yang, Dong-Ho,Yoo, In-Sik 척추신경추나의학회 2009 척추신경추나의학회지 Vol.4 No.2

        Objectives : The purpose of this study is to report clinical effects of oriental medical treatments with acupuncture treatment on peroneus longus muscle for two patients with foot drop by Herniated Intervertebral Lumbar Disc(HIVD). Method : The patients were diagnosed as HIVD, and were treated by oriental medical treatments including acupuncture treatment on peroneus longus muscle. And we measured Visual Analogue Scale(VAS), Range of Motion (ROM) of ankle joint, Manual Muscle testing(MMT) and checked the subject power of ankle joint. Result : After acupuncture treatment on peroneus longus muscle, the movement and power of ankle joint were improved in two cases. Conclusion : Acupuncture treatment on peroneus longus muscle showed significant effect on two patients with foot drop patients by HIVD.

      • KCI등재

        요통환자의 Lumbar Lordotic Angle, Ferguson’s Angle과 골밀도에 대한 상관성

        이한,차윤엽 대한침구의학회 2009 대한침구의학회지 Vol.26 No.4

        Objectives : The purpose of this study is to investigate correlations between lumbar lordotic angle(LLA), Ferguson’s angle(FA) and bone mineral density(BMD) in patients with low back pain. Methods : We measured LLA, FA and BMD of 199 patients with low back pain. Then we analyzed correlations between LLA, FA and BMD using statistical program. Results : There was significant correlation between LLA and FA, and also between age, height and BMD. There was no significant correlations between LLA, FA and BMD. BMD of paitients also showed no significant correlations with LLA and FA according to age and sex. Conclusions : BMD had no significant effect on LLA and FA. On the other hand, there was significant correlation between LLA and FA.

      • KCI등재후보

        BCAA 섭취가 중추피로변인 및 지구성 운동수행 능력에 미치는 효과

        이한,홍미경,신선애,손태열,안의수,김완수,홍용 한국운동과학회 2002 운동과학 Vol.11 No.1

        이 한, 홍미경, 신선애, 손태열, 안의수, 김완수, 홍 용. BCAA섭취가 중추피로변인 및 지구성 운동수행 능력에 미치는 효과. 운동과학, 제11권 제1호, 25-34, 2002. 본 연구는 탈진적인 지구성 운동시 BCAA (Branched-chain amino acid)섭취가 중추피로의 주 요인인 세로토닌 및 암모니아 농도와 지구성 운동수행능력에 미치는 효과를 실험적으로 구명하는데 목적을 두었다. 실험대상자는 고등학교 싸이클 선수 9명으로 각 피험자의 70%VO_2max의 강도로 자전거 에르고메터를 이용하여 탈진시까지 운동을 실시하였으며, BCAA는 피험자의 체중당 78㎎을 역삼투수 500㎖에 용해시켜 구강 섭취하였다. BCAA와 위약섭취시기의 실험조건을 동일하게 하였으며, BCAA와 위약을 교차하여 섭취하는 무작위처치를 이용하였다. 채혈은 카테터를 전완정맥에 삽입하여 제재섭취전, 제재섭취 50분 후, 운동중 30분, 운동직후(탈진) 및 회복기 30분에 각각 10㎖씩 채혈하였다. 혈장 BCAA 및 BCKA치 농도는 BCAA섭취시 유의하게 증가한 것으로 나타났으며, 혈장 암모니아농도는 운동시 BCAA섭취에서 증가하였지만 유의한 차이를 나타내지는 않았다. 혈중 젖산 및 혈장 트립토판의 농도는 BCAA섭취 시 감소하였으나 유의한 차이는 없었으며, 혈장 세로토닌 농도는 BCAA섭취 시 유의하게 감소한 것으로 나타났다. 또한, 주관적 운동강도(RPE) 및 지구성 운동수행시간은 BCAA섭취 시 증가하였으나 유의한 차이는 나타나지 않았다. Lee, K, Hong M.K., Shin, S.A, Son, T.Y., Ann, ES., Kim, W.S., Hong, Y. The Effect of BCAA Administration on the Central Fatigue and Endurance Exercise Capacity. Exercise Science, 11(1): 25-34, 2002. The purpose of this study was to estimate the effect of the BCAA(branched-chain amino acid) administration on serotonin and ammonia concentrations that were central fatigue main factors, and endurance exercise capacity during exhaustive endurance exercise. 9 male cycle players of high school were chosen as subjects of this study, and BCAA(78㎎/㎏·w) solved in distilled water 500㎖ were administrated to them and exhaustive endurance exercise was executed by using 70%VO_2max intensity to cycle ergometer. Experimental conditions of BCAA and placebo administration were the same and randomized ingestion were used. The time of inserting catheter was earlier agents administration and the blood sampling time were just before agents administration, 50minutes after agents administration, exercise 30 minutes, exhaustion, recovery 30 minutes, 10㎖ blood was taken. Plasma BCAA and BCKA concentrations were significantly increased (p<.05) when BCAA administration, plasma ammonia concentration was increased when BCAA administration but there was not significant. Blood lactate and plasma trytophan concentrations were decreased when BCAA administration but there was not significant, plasma serotonin was significantly decreased(p<.05) when BCAA administration. RPE and exercise time were decreased when BCAA administration but there was not significant.

      • 지구성 운동 시 Branched-chain amino acids와 Ornithine α-Ketoglutarate 혼합섭취가 중추피로에 미치는 영향

        이한 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

        The purpose of this study was to estimate the effect of Compound with trenched-chain amino acid and ornithine a-ketoglutarate administration on plasma serotonin and amino acids concentration that was central fatigue factors during endurance exercise with exhausted, 9 male high school cycling players were participated as subjects of this study and BCAA+OKG 78㎎/㎏·w solved in distilled water 500㎖ were administrated to them and exhaustive endurance exercise was executed by using 70%VO₂max intensity to cycle ergometer. Experimental conditions of BCAA+OKG and placebo administration were the same and randomized ingestion were used, The time of inserting catheter was earlier agents administration and the blood sampling time were just before agents administration, 50minutes after agents administration, exercise 30 minutes, exhaustion, recovery 30 minutes and at every five each time, 10㎖ blood was taken. The results are as follows after analysing plasma ammonia, glutamate, glutamine, ornithine. Tryptophan, alanine, serotonin, BCAA, BCKA, blood lactate concentration in blood and changes of exercise time according to BCAA+OKG administration, When BCAA+OKG administration was carried out, compared with placebo administration, there was significant decrease in plasma ammonia, serotonin, trytophan blood lactate concentration(P<.05). Plasma glutamate, glutamine, ornithine, alanine, BCAA, and BCKA concentration were increased significantly(P<.05) when BCAA+OKG administration was carried out. And exercise time was also increased average 8 minuets above when BCAA+OKG administration. In conclusion, it was certain that the simulaneous administration of BCAA+OKG intake and could be inhibited the serotonin of concenfration and the ammonia of concenfration and improve endurance performance.

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