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이한비,정명자,김수현,김성희,김지영,김재형 대한초음파의학회 2008 ULTRASONOGRAPHY Vol.27 No.1
A schwannoma of the gallbladder is an extremely rare tumor. We report a case of a 45-year-old woman with a polypoid mass in her gallbladder. The mass was discovered incidentally as a heterogeneous enhancing mass in the infundibulum of the gallbladder on an abdominal CT scan performed during an evaluation of a reported nonspecific left lower abdominal pain. An ultrasonography revealed that the overlying mucosa of gallbladder was intact. Moreover, a laparoscopic cholecystectomy was performed and the mass was confirmed as a gallbladder schwannoma. A schwannoma of the gallbladder is an extremely rare tumor. We report a case of a 45-year-old woman with a polypoid mass in her gallbladder. The mass was discovered incidentally as a heterogeneous enhancing mass in the infundibulum of the gallbladder on an abdominal CT scan performed during an evaluation of a reported nonspecific left lower abdominal pain. An ultrasonography revealed that the overlying mucosa of gallbladder was intact. Moreover, a laparoscopic cholecystectomy was performed and the mass was confirmed as a gallbladder schwannoma.
유방의 촉진성 종괴로 나타난 해면형 혈관종: 증례 보고
이한비,김성희,김재형,김지영,정명자,김수현,전우선 대한영상의학회 2009 대한영상의학회지 Vol.60 No.3
Vascular tumors of the breast are uncommon and include angiosarcomas and hemangiomas. Most vascular tumors of the breast are angiosarcomas, and benign hemangiomas of the breast are rare. We report a case of a cavernous hemangioma of 51-year-old woman, which was located in the subcutaneous layer of a palpable site in the right breast and was a probable benign lesion. 유방의 혈관성 종양은 흔하지 않고 혈관육종(angiosarcoma)과 혈관종(hemangioma)을 포함한다. 이중 대부분은 혈관육종이고 양성 혈관종은 드물지만, 종괴가 피하층에 위치하는 경우 대체로 양성 병변이라고 알려져 있다. 저자들은 우측 유방에 만져지는 종괴로 내원한 51세 여성에서 만져지는 부위의 피하층에 위치하는 양성추정 종괴로 보였던 해면형 혈관종(cavernous hemangioma)을 경험하였기에 이의 영상의학적 소견을 보고하고자 한다.
이한비,정태용,최창수 한국비교정부학회 2018 한국비교정부학보 Vol.22 No.3
The goal of this paper is to find out how climate change governance of China, Japan, and Korea transformed between 1997 and 2015. From a comparative perspective, this study examines the role of three key sectors – the government, the private sector, and civil society – and their interactions around the adoption of the Kyoto Protocol in 1997 and the Paris Agreement in 2015. Climate change governance of China is led by the government with unwavering support from the highest leadership pursuing national rejuvenation based on low-carbon development. The number and diversity of the non- governmental sectors in China have significantly increased, but they fall short of exerting significant influence on the government. Japan’s governance resulted in a proactive 6% reduction target with support from civil society in 1997, but the government has backslid thanks to the economic stagnation and the Fukushima accident since the Kyoto Protocol. Thereafter, policy decisions have been made in favor of the private sector with little input from the NGOs. It is uncertain to assert whether there existed climate change governance in Korea at the time of the Kyoto Protocol. However, the private sector and the civil society had gained more leverage regarding climate change governance in the advent of the Paris Agreement. Despite the differences, the three countries seem to share one in common, that is, the growing influence of the private sector and civil society in climate change governance.
이한비,Yin-Chuan Ji,김승우,김일두,이혜경,이자경 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
Osteopontin (OPN) is a phosphorylated glycoprotein secreted into body fluids by various cell types. OPN contains arginine-glycineaspartate (RGD) and serine-leucine-alanine-tyrosine (SLAY) motifs that bind to several integrins and mediate a wide range of cellular processes. In the present study, the proangiogenic effects of a 20-amino-acid OPN peptide (OPNpt20) containing RGD and SLAY motifs were examined in human umbilical vein endothelial cells (HUVECs) and in a rat focal cerebral ischemia model. OPNpt20 exerted robust proangiogenic effects in HUVECs by promoting proliferation, migration and tube formation. These effects were significantly reduced in OPNpt20-RAA (RGD-4RAA)-treated cells, but only slightly reduced in OPNpt20-SLAA (SLAY-4SLAA)- treated cells. Interestingly, a mutant peptide without both motifs failed to induce these proangiogenic processes, indicating that the RGD motif is crucial and that SLAY also has a role. In OPNpt20-treated HUVEC cultures, AKT and ERK signaling pathways were activated, but activation of these pathways and tube formation were suppressed by anti-αvβ3 antibody, indicating that OPNpt20 stimulates angiogenesis via the αvβ3-integrin/AKT and ERK pathways. The proangiogenic function of OPNpt20 was further confirmed in a rat middle cerebral artery occlusion model. Total vessel length and vessel densities were markedly greater in OPNpt20-treated ischemic brains, accompanied by induction of proangiogenic markers. Together, these results demonstrate that the 20-amino-acid OPN peptide containing RGD and SLAY motifs exerts proangiogenic effects, wherein both motifs have important roles, and these effects appear to contribute to the neuroprotective effects of this peptide in the postischemic brain.
토픽 모델링을 활용한 국내외 정의로운 전환 연구동향 비교분석
이한비 한국기후변화학회 2022 한국기후변화학회지 Vol.13 No.6
Just transition originates from the labor movement urging to protect fossil fuel workers from the impact of low-carbon transition policies. It has evolved to address an integrated framework of climate, energy, and environmental justice during the transition to a low/zero-carbon society. Recent years have seen a rapid boom surrounding the theorization of just transition. However, relatively few studies have examined how the concept of just transition is applied to research across academic disciplines or under what research agenda just transition would encompass different concerns addressed by environmental, climate, and energy justice scholarship. Against this backdrop, this article sets out to investigate the main topics being discussed in just transition and climate-energy-environmental justice literature, and the similarities and differences between the global and Korean scholarship using topic modeling. The results demonstrate that city and local transitions have emerged as key topics while the focus of scholarly debates has shifted from regional pollution to global sustainability issues in the foreign literature after the Paris Agreement. In the Korean literature, institution-related topics rapidly increased after 2008, wherein green growth strategies were introduced. Yet, local issues, industry and jobs replaced these topics after the Paris Agreement. By comparing the results, the article draws implications for Korean scholarship to better understand just transition as an integrated framework of climate, energy, and environmental justice.