농촌지역 노인들의 우울 및 인지기능장애에 관한 연구

이정애,정향균,Rhee, Jung-Ae,Jung, Hyang-Gyun 대한예방의학회 1993 Journal of Preventive Medicine and Public Health Vol.26 No.3

For the purpose of promotion of mental health in the rural elderly, the author surveyed 558 elderlies aged 60 years or more, and assessed the prevalence rates of depression and cognitive impairment by using self-rating depression scale of Zung (SDS) and the Korean version of mini-mental state examination (MMSEK). Also the association between depression or cognitive function and socio-environmental factors were investigated. The major findings were as follows ; 1. The prevalence rates of severe depression and cognitive impairment were 20.9% and 14.9% in all the elderly of both sexes, respectively. 2. The rates of depression and cognitive impairment increased with increasing age in both sex groups. The mean scores of SDS increased and the mean scores of MMSEK decreased significantly among them (p<0.01). 3. Those being female, widows or widowers, and those having low levels of physical activity, showed significantly high the mean scores of depression and had significantly low the mean scores of cognitive impairment (p<0.01). 4. The depression scores relating to decreased libido, confusion, psychomotor retardation, hopelessness and indecisiveness were relatively high in both sexes. 5. All the items of mini-mental state examination were significantly correlated with depression. 6. In stepwise multiple regression analysis on depression, MMSEK, level of physical activity, chronic disease, marital status and family income were selected as highly correlated variables, and the $R^2$-value for these variables was 33.7%. 7. In stepwise multiple regression analysis on cognitive function, level of physical activity, age, depression, sex and marital status were selected as highly correlated variables, and the $R^2$-value for these variables was 62.6%. The depression and cognitive impairment of the elderly were positively correlated with nearly all sociodemographic variables.

농촌지역 노인들의 인지기능 장애와 사망과의 관련성

선병환,박경수,나백주,박요섭,남해성,신준호,손석준,이정애,Sun, Byeong-Hwan,Park, Kyeong-Soo,Na, Baeg-Ju,Park, Yo-Seop,Nam, Hae-Sung,Shin, Jun-Ho,Sohn, Seok-Joon,Rhee, Jung-Ae 대한예방의학회 1997 예방의학회지 Vol.30 No.3

60세이상 노인인구를 대상으로 '농촌지역 노인들의 우울 및 인지기능 장애에 관한 연구'를 한 이정애와 정향균의 연구대상 558명에 대해 농촌지역 노인들의 인지기능 장애와 사망과의 관련성을 살펴본 결과는 다음과 같다. 1) 3년동안 동안 전체 대상자의 사망률은 558명중 57명인 10.2%이었으며 353명의 정상 인지기능군 중 사망자는 30명으로 사망률 8.5%, 126명 의 경도 인지장애군중 사망자는 14명으로 사망률 11.1%, 79명의 중증 인지장애군중 사망자는 13명으로 사망률 16.5% 이었다(표 3). 2) 3년동안 전체 연구 대상자의 생존율은 0.91이었으며 정상, 경도, 중증 인지기능 장애군의 3년 생존율은 각각 0.92, 0.90, 0.86이었다. 로그 순위 검정법으로 인지기능 정상군과 경도 및 중증의 각 인지기능 장애군의 생존곡선을 비교한 결과 통계적으로 유의하지 않았다. 또한 인지기능 정상군과 경도 이상의 인지기능 장애군간 생존곡선을 비교한 결과도 유의한 차이는 없었다. 3) 혼란변인을 보정하지 않는 Cox의 비례위험 회귀 모형의 단변량분석의 결과 95% 신뢰구간(C.I. : Confidence Interval)에서 사망위험도가 유의한 변인은 연령, 월수입, 흡연습관, 신체장애 등이었으며, 인지기능 장애정도를 정상 그리고 경도 및 중증으로 분류한 분석에서는 정상군에 비해 경도 및 중증의 사망위험도가 유의하게 높지 않았으나, 인지기능 점수(MMSEK score)의 증가에 따른 분석 결과 사망위험도가 0.94로 유의하게 낮게 나타났다(표 4). 4) 잠재적 혼란변인들의 영향을 보정한 Cox의 비례위험 회귀모형의 다변량 분석의 결과 인지기능 장애정도 및 MMSEK 점수증가에 따른 사망위험도는 어느 모형에서도 인지기능 장애정도가 사망에 미치는 위험도는 통계적으로 유의하지 않았다(표 5). 5) 남녀별로 각각 인지기능 장애와 사망위험도와의 관계를 알아보기 위해 다변량 분석을 시행한 결과 인지기능 장애정도 및 MMSEK 점수 증가에 따른 사망위험도는 어느 모형에서도 인지기능 장애정도가 사망에 미치는 위험도는 통계적으로 유의하지 않았다(표 6, 표 7). 이상 본 연구는 농촌지역 노인들에서 인지기능 장애정도가 사망에 미치는 영향을 알아보고자 하였지만, 인지기능 장애정도가 사망에 미치는 영향을 통계적으로 유의하게 고찰하지 못하였다. The purpose of this study was to examine the mortality risk associated with cognitive impairment among the rural elderly. The subjective of study was 558 of 'A Study on the Depression and Cognitive Impairment in the Rural Elderly' of Jung Ae Rhee and Hyang Gyun Jung's study(1993). Cognitive impairment and other social and health factors were assessed in 558 elderly rural community residents. For this study, a Korean version of the Mini-Mental State Examination(MMSEK) was used as a global indicator of cognitive functioning. And mortality risk factors for each cognitive impairment subgroup were identified by univariate and multivariate Cox regression analysis. At baseline 22.6% of the sample were mildly impaired and 14.2% were severely impaired. As the age increased, the cognitive function was more impaired. Sexual difference was existed in the cognitive function level. Also the variables such as smoking habits, physical disorders had the significant relationship with cognitive function impairment. Across a 3-year observation period the mortality rate was 8.5% for the cognitively unimpaired, 11.1% for the mildly impaired, and 16.5% for the severly impaired respendents. And the survival probability was .92 for the cognitively unimpaired, .90 for the mildly impaired, and .86 for the severly impaired respondents. Compared to survival curve for the cognitively unimpaired group, each survival curve for the mildly and the severely impaired group was not significantly different. When adjustments models were not made for the effects of other health and social covariates, each hazard ratio of death of mildly and severely impaired persons was not significantly different as compared with the cognitively unimpaired. But, as MMSEK score increased, significantly hazard ratio of death decreased. Employing Cox univariate proportional hazards model, statistically other significant variables were age, monthly income, smoking habits, physical disorders. Also when adjustments were made for the effects of other health and social covariates, there was no difference in hazard ratio of death between those with severe or mild impairment and unimpaired persons. And as MMSEK score increased, significantly hazard ratio of death did not decrease. Employing Cox multivariate proportional hazards model, statistically other significant variables were age, monthly income, physical disorders. Employing Cox multivariate proportional hazards model by sex, at men and women statistically significant variable was only age. For both men and women, also cognitive impairment was not a significant risk factor. Other investigators have found that cognitive impairment is a significant predictor of mortality. But we didn't find that it is a significant predictor of mortality. Even though the conclusions of our study were not related to cognitive impairment and mortality, early detection of impaired cognition and attention to associated health problems could improve the quality of life of these older adults and perhaps extend their survival.

건일로딘 정(미결정에토돌락 200 mg)에 대한 에토돌 정의 생물학적동등성

이정애,이윤영,조태섭,박영준,문병석,김호현,이예리,이희주,이경률,Lee, Jung-Ae,Lee, Yun-Young,Cho, Tae-Seob,Park, Young-Joon,Moon, Byoung-Seok,Kim, Ho-Hyun,Lee, Ye-Rie,Lee, Hee-Joo,Lee, Kyung-Ryul 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.4

A bioequivalence of $Etodol^{TM}$ tablets (Yuhan corporation) and $Kuhnillodine^{TM}$ tablets (Kuhnil Pharm. Co., Ltd.) was evaluated according to the guideline of Korea Food and Drug Administration (KFDA). Single 200 mg dose of etodolac of each medicine was administered orally to 24 healthy male volunteers. This study was performed in a $2{\times}2$ crossover design. Concentrations of etodolac in human plasma were monitored by a high-performance liquid chromatography. $AUC_t$ (the area under the plasma concentration-time curve from time zero to 24 hr) was calculated by the linear trapezoidal rule method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was performed using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for $Etodol^{TM}/Kuhnillodine^{TM}$ were 1.01-1.10 and 0.87-1.06, respectively. This study demonstrated a bioequivalence of $Etodol^{TM}$ and $Kuhnillodine^{TM}$ with respect to the rate and extent of absorption.

환기(換氣)가 불량(不良)한 실내(室內)에서의 간접흡연(間接吸煙)에 관(關)하여

이정애,Rhee, Jung-Ae 대한예방의학회 1981 예방의학회지 Vol.14 No.1

This study was conducted to investigate the effects of passive inhalation of cigarette smoke and the correlation between change of flicker value and active or passive smoking in poorly ventilated room. Forty five male students were tested by divided into four experimental groups composed of active and passive smokers and three control groups. Each four experimental groups were exposed to smoke for Two hours in enclosed room. Vital capacities, flicker values, blood carboxyhemoglobin levels and carbon monoxide concentration in room air were estimated before, during and after the exposure, and amounts of smoking or smoke exposure during two hours were also noted. The results obtained were as follows; 1. Concentration of carbon monoxide in air and increase of blood carboxyhemoglobin level (% COHb) were positively correlated with smoking amount. 2. Increase of blood carboxyhemoglobin in passive smokeres, in average, were about seventy six percent of that in smokers, as 2.2% vs. 2.9%. 3. Comparison with published data showed that Peterson's equation gave most similar result to this study in estimation of increase of blood carboxyhemoglobin level. 4. During the exposure, flicker values fell steadily in both experimental groups and control groups as time passed. Flicker values were, however, elevated again in experimental groups after exposure, despite the fact that values still fell in control groups. 5. Blood carboxyhemoglobin and flicker value were negatively correlated and this correlationship was stronger in passive smoker than in active smoker. 6. Multiple regression equation between flicker value and exposure time and blood carboxyhemoglobin level was expressed as: Flicker value=41.6-0.2 COHb%-0.9Hour, 7. In general, it is suggested that biological criteria would be more preferrable than chemical criteria in establishment of statutory limitation of smoking in enclosed spaces.

예방의학회지를 중심으로 한 예방의학 연구의 동향과 연관련 논문의 질적 메타분석

이정애,박종구,손석준,김춘배,Rhee, Jung-Ae,Park, Jong-Ku,Sohn, Seok-Joon,Kim, Chun-Bae 대한예방의학회 1999 예방의학회지 Vol.32 No.2

Objectives: The purpose of this study was to describe the trends of original research in the Korean Journal of Preventive Medicine, and to evaluate the quality of original articles about lead poisoning. Method: The data for the analysis of trends in preventive medicine research was taker from a total of 829 original articles published in the Korean Journal of Preventive Medicine from 1968 to 1997, The qualitative meta-analysis was measured against a checklist of evaluation criteria, which were divided into 10 categories, with 46 articles on lead poisoning. The evaluation process was performed independently by two evaluators, Results: The number of articles per 100 members over the study period increased by almost 4 pieces in the early 1980s, and by more than 9 pieces in the mid-1990s. In the major classifications of subjects, environmental and industrial health, epidemiology and health statistics, and health policy and management published 370 pieces (44.0%), 137 pisces (16.5%), 322 pieces (38.9%) respectively. In the order of the number of articles, five themes about health significance, including metal exposure (73 pieces), diseases associated with exposure to organic solvents (45 pieces), air pollution (36 pieces), maternal and child health (32 pieces), and occupational health (3D pieces) received consistent attention throughout the years $1968\sim1997$. The overall mean score of article qualify about lead poisoning was 37.8 out of 50. Of the articles any information on the purpose and hypothesis described well, Of those the originality of the subjects, the form of article's (including tables and figures), and the number of inappropriate words of abstracts showed very low score. For multiple regression analyses, the number of joint research institutes and the acceptance of research grants about the article quality were statistically significant. Conclusions: The number of original research reports in the Korean J Prev Med has recently increased and their subjects bave diversified. Of the basis of this study, the articles need improvement in the areas of abstracts, tables and illustrations (figures), etc. The Korean Society for Preventive Medicine will revise contribution regulations for manuscripts submitted to the Korean J Prev Med. Future studies should address these issues and perform the quantitative mata-analysis about the specific subjects including the quality of articles.

Perceptions of nurses as a profession in Korea

이정애,염영희,Yee, Jung-Ae,Yom, Young-Hee Korean Academy of Nursing Administration 2001 간호행정학회지 Vol.7 No.3

연구목적 : 전문직으로서 간호사에 대한 인식을 집단별로 파악하고 이들에 대한 인식을 비교한다. 연구방법 : 설문지를 이용한 비교조사연구로서 조사대상은 간호사, 간호학교수, 의사, 약사, 간호조무사, 병원행정직원, 행정관료, 정당활동가, 일반시민 등을 포함한 총 584명이었으며, 설문지는 12개 하부항목으로 범주화된 36개 문항으로 구성되었다. 연구결과 : 간호사에 대한 인식은 의사가 가장 긍적적이었으며, 병원직원이 가장 부정적이었다. 모든 집단에서 가장 긍정적인 인식을 갖고 있는 항목은 '사회적 요구'였으며, 그 다음은 '직무기술', '사회적 인식' 등의 순으로 나타났다. 가장 부정적인 것은 '간호교육'이었고, 그 다음은 '간호조직체 활동', '직무환경' 순으로 나타났다. 결론 : 본 연구를 기초로 하여 간호사들은 다른 집단들을 대상으로 전문직으로서의 간호사에 대한 인식을 높이기 위한 전략을 마련하여야 한다.

인상채득 후 경화시 트레이의 위치에 따른 주모형의 변화

이정애 ( Jung Ae Lee ) 한국치위생학회 2008 한국치위생학회지 Vol.8 No.2

가정외보호 퇴소아동의 자존감과 사회적 지지가 자립생활기술에 미치는 영향 : 공동체 의식의 매개효과

이정애 ( Lee Jung-ae ),이화조 ( Lee Hwa-jo ),정익중 ( Chung Ick-joong ) 전북대학교 사회과학연구소 2017 지역과 세계 Vol.41 No.1

본 연구는 가정외보호 퇴소아동의 자립생활기술에 영향을 미치는 요인에서 자존감, 사회적 지지와 자립생활기술 간의 관계를 규명하고자 한다. 특히, 기존 선행연구에서 다루었던 위험요인과 문제 중심적인 시각에서 벗어나, 이들을 긍정적 관점에서 지지할 수 있는 보호요인에 주목하였다. 구체적으로 퇴소아동의 자존감과 사회적 지지가 자립생활기술에 영향을 미치는지, 그 관계에서 공동체 의식이 매개하는지 살펴보았다. 이를 위해 아동양육시설 퇴소아동을 대상으로 진행된 보건복지인력개발원 아동자립지원단의 설문 자료를 활용하였고, 총 656명의 퇴소아동을 통계분석에 활용하였다. 분석 결과, 자존감과 사회적 지지는 자립생활기술에 직접적인 영향을 미치고, 공동체 의식은 부분매개효과를 통해 이 관계들에 간접적인 영향을 미치는 것으로 나타났다. 이를 바탕으로 가정외보호 퇴소아동의 자립과 건강한 성인으로 성장할 수 있도록 사회복지 실천적·정책적 함의를 제언하였다. The purpose of this study was to identify the factors influencing the independent living skills of youth discharged from out-of-home care. In particular, we focused on protective factors from a positive point of view, apart from the risk factors and problem-focused perspective in previous studies. We examined whether self-esteem and social support affect the independent living skills and whether sense of community mediates these relationships. We used data from Youth Support Center for Independence Living which conducted a survey for youth discharged from out-of-home care. A total of 656 youth were used for statistical analyses. The results showed that self-esteem and social support had positive effects on the independent living skills of youth discharged from out-of-home care; and the sense of community had the partial mediation effects. Based on the results, we suggested social welfare practice and policy implications so that youth discharged from out-of-home care can be self-reliant and grow into healthy adults in the future.

일부 대학생들에 있어서 생활습관과 신체 및 정신건강도와의 관련성

이정애(Jung Ae-Rhee),이윤지(Youn Ji Lee) 한국농촌의학 지역보건학회 1993 농촌의학·지역보건 Vol.18 No.2

국내 육성 사과 신품종 ‘썸머킹’, ‘그린볼’, ‘아리수’의 경북 영주지역에서의 생육 특성

이정애(Jung-Ae Lee),우병용(Byong-Yong Woo),전우영(Woo-Yeong Jeon),김병각(Byeong-Gak Kim),이갑수(Kab-Soo Lee),권순일(Soon-Il Kwon) 한국원예학회 2013 한국원예학회 학술발표요지 Vol.2013 No.5