대분청음(大分淸飮)이 Cisplatin으로 유발(誘發) 된 흰쥐의 급성신부전(急性腎不全)에 미치는 영향(影響)

이연경,윤경민,장수영,강석봉,Lee, Yeon-Keong,Yoon, Kyeong-Min,Jang, Su-Yeong,Kang, Seok-Bong 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.4

Purpose : This study was to observe the nephroprotective effects of the traditional prescription, Daebuncheong-eum (DBCE). DBCE has generally been used for treating various renal diseases, including renal failure. Methods : Three different dosages of DBCE extract were orally administered once a day for 28 days. At the 23rd day after DBCE extract treatment, cisplatin was also treated. Then, 5 days after cisplatin treatment, all rats (6 groups of 8 rats each) were sacrificed. Changes on the body weight, kidney weight, serum BUN and creatinine levels were observed, along with changes to the kidney MDA and GSH contents. The results were compared with captopril 100mg/kg, from which the effects on cisplatin-induced acute renal failures have already been confirmed. Results : Cisplatin induced ARF are induced by oxidative stress and related lipid peroxidation in the present study. However, these ARFs and inhibition of antioxidant effects induced by cisplatin were dose-dependently reduced by treatment of all three different dosages of DBCE extracts. Conclusion : This study suggests that DBCE extracts show favorable effects on cisplatin-induced rat ARF.

당뇨병 및 소갈(消渴)의 최신 연구 동향 -2003년에서 2007년까지 한의학술논문을 중심으로-

이연경,최규호,신현철,강석봉,Lee, Yeon-Kyeong,Choi, Geu-Ho,Shin, Hyun-Cheol,Kang, Seok-Bong 대한한의학방제학회 2007 大韓韓醫學方劑學會誌 Vol.15 No.2

At this moment, because there're lots of necessity to have an attention on diabetus mellitus (DM), in this article searched over all the Korean oriental medical academic journals about DM from 2003 to 2007, Method: Through data base system that Daegu Haany University affiliated information center & Korean Studies Information Center manage, selected 60 articles worthy to look up that are searched by the keyword 'DM' & '消渴'. Result and Conclusion: 5 articles of observing 'DM' & '消渴' itself academically, 29 articles of experimental study, 8 articles of clinical research study and 18 articles of case report. For experimental study, mostly it were concerning type II DM modeled rat medicated herb and its effect, so there were only a few type I experimental study. For observing articles, generally the causes, pathology, treatments, acupuncture methods and medication et al., variable studies were done. In clinical research, diverse categories were subject, which is to prove the efficacy of medication, acupuncture, physical therapy and diet supplements. And in case reports, focused not only on improvement in blood sugar level but also its complications.

부평의 노무자주택을 통해 본 전시체제기 주택의 특징과 산업유산으로서의 가치

이연경,Lee, Yeon-Kyung 한국건축역사학회 2021 건축역사연구 Vol.30 No.3

Since 1939, Bupeyong was rapidly urbanized and industrialized for the purpose of constructing military logistics base of the empire of Japan. Based on Kyungin urban planning of 1940 and industrial land development plan of Kyeonggido, many military factories and arsenal were constructed, and great amount of housing were also built for their workers from 1939 to 1944. Although the initial urban planning was unfinished, urban change from rural area to military industrial city in the late Japanese colonial era, made identity of city of Bupyeong. Workers houses which built during five years vary in different size and type, and somewhat reflects discussions about housing attempts to solve the housing shortage. This study aims to analyze architectural characteristics of workers housing related with discussions of housing, and to evaluate its value as an industrial heritage which constitute the urban landscape of the industrial city of Bupyeong. Workers houses in Bupyeong were constructed by military factories, construction company, and Chosun housing administration, with land readjustment planning. As the war became serious, workers housing became smaller and simpler. Construction of workers housing was essential part of modern military industrial city, bupyeong, and many of workers housing are still remained whereas most of factories were demolished, thus workers housing of bupyeong has significant meaning as industrial heritage of Bupyeong.

가미오령산(加味五?散)이 Streptozotocin으로 유발된 흰쥐의 당뇨병성(糖尿病性) 신증(腎症)에 미치는 영향

이연경,강석봉,Lee, Yeon-Kyeong,Kang, Seok-Bong 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.4

Objectives : The object of this study was to observe the effects of Gamioryung-san (GOS), which consists of 22 types of herbs, on streptozotocin (STZ)-induced diabetic nephropathy rats. Methods : Three different dosages of GOS were orally administered once a day for 28 days from 3 weeks after STZ treatment. Six groups, each of 8 rats per group were used. Changes on the body weights, blood glucose levels, serum BUN and creatinine levels, urine volumes, and UAER were observed with changes on the kidney malondialdehyde contents and glutathione, dismutase and catalase contents. In addition, histopathology of kidney, pancreas, thymus and spleen were observed. The results were compared with antioxidant silymarin 100 mg/kg, of which the effects on STZ -induced diabetes and related complications are already confirmed. Results : As a result of treatment of GOS 800, 400 or 200 mg/kg for 28 days, STZ-induced decreases of body weights, hyperglycemia, atrophic changes of pancreatic islets with decreases of insulin-immunoreactive cells and decreases of glucagon -immunoreactive cells were inhibited dose-dependently. Increases in kidney weight, serum BUN and creatinine levels, urine volumes, UAER, vasodilated atrophic glomerulus and abnormal tubules were inhibited dose-dependently. Also increases of kidney MDA contents and decreases of GSH contents, SOD and CAT activities, decreases of thymus and spleen weights, and atrophic changes at histopathological observation were also inhibited. The effects of GOS 400 mg/kg showed similar effects to silymarin 100 mg/kg. Conclusions : These results suggest that 400 mg/kg of GOS retarded the STZ-induced diabetic nephropathies as similarly to silymarin 100 mg/kg, through modulations of oxidative stress and immune systems.

1차원 Cu(II)배위 고분자의 합성 및 구조: [Cu(bdcH)₂(bipyen)] (bdc=1,3-benzenedicarboxylate; bipyen=trans-1,2-bis (4-pyridyl)ethylene)

이연경,이순원,Lee, Yeon Gyeong,Lee, Sun Won 대한화학회 2002 대한화학회지 Vol.46 No.5

서울 상업용도지역 내 주거 기능 회복의 필요성과 방향 -서울 역사도심과 뉴욕 맨해튼을 중심으로-

이연경,이경민,최원우,신중호,김도년,Lee, Youn-Kyung,Lee, Kyung-Min,Choi, Won-Woo,Shin, Jung Ho,Kim, Do-Nyun 국제문화기술진흥원 2022 The Journal of the Convergence on Culture Technolo Vol.8 No.6

The purpose of this study is to present the problems of urban ecosystem imbalance in Seoul and the need to restore housing functions through comparison with Manhattan, New York, which grew earlier than Seoul and has been striving to solve urban problems and restore urban ecosystems. The residential status in urban commercial use areas was investigated through analysis of the total amount of residential space, characteristics of each type of residential building, and distribution of residential buildings. Through this, it can be seen that most of the space in Seoul's historic city center is biased toward commercial roads, and there are significantly insufficient high- and high-density mixed-use buildings suitable for urban dwellings compared to Manhattan's. In addition, it can be seen that the complex building in the historical city center of Seoul is located adjacent to the outskirts of the target site. In conclusion, Seoul's historical city center does not provide an appropriate residential space for creating an urban ecosystem, and it is necessary to come up with measures to restore housing functions.

새로운 소비자, 새로운 시장, 할랄 보충제

이연경,Lee, Yeon Kyung 한국식품과학회 2015 식품과학과 산업 Vol.48 No.2

목방기약침(木防己藥鍼)이 관절염(關節炎)에 미치는 영향(影響)

이연경,이병렬,Lee, Yeun-kyung,Lee, Byung-ryul 대한침구의학회 2001 대한침구의학회지 Vol.18 No.4

Objective : The purpose of this study is to observe the effect of Aqua-acupuncture with Stephania Tetrandra Solution (ST-AS) on arthritis. Methods : The author performde several experimental items : that isgene expression and secretion of IL-$1{\beta}$, IL-6, TNF-${\alpha}$, MMP-2, production of ROS, paw thickness, DTH, weight of spleen, expression of CD4+, CD8+, CD19+ in the spleen, production of IL-6, TNF-${\alpha}$, examination of histology. Results : The obstain results are summarized as follows. 1. IL-$1{\beta}$, IL-6, TNF-${\alpha}$ gene expression of hFLS were significantly inhibited in treatmentgroup, and gene expression of MMP-2 was not inhibited in treatmentgroup. 2. The secretion amount of IL-$1{\beta}$, IL-6, TNF-${\alpha}$ were significantly inhibited in treatmentgroup. 3. Expression of P-38 MAP kinase and production of ROS were inhibited in treatmentgroup. 4. Treatmentgroup were significantly inhibited the incidence of arthritis, hind paw edema, the index of arthritis and DTH of CIA (collagen II-induced arthritis) mice. 5. Treatmentgroup were significantly decreased splenetic weight and the number of CD4+, CD8+, CD19+ activated cells and secretion aroout of IL-6, TNF-${\alpha}$ of CIA (collagen II-induced arthritis) mice.. 6. Treatmentgroup were expressed form of new bone, synoviumin, new margine in histology imperison to controlgroup. Conclusions : Taking all these observations into account, ST-AS injection is considered to be effective in treating arthritis and put to practical use in future arthritis clinic.

이중 문턱 값과 적분영상을 이용한 2차원 바코드 영상의 적응적 이진화

이연경,유훈,Lee, Yeon-Kyung,Yoo, Hoon 한국정보통신학회 2012 한국정보통신학회논문지 Vol.16 No.11

본 논문에서는 2차원 바코드 영상을 위한 적응적 이진화 방법을 제안한다. 적응형 이진화 방법은 조명의 영향을 최소화하여 이진화를 수행하는 기술이다. 적응적 이진화 방법은 주로 문서 영상에 맞게 발전되어 왔다. 기존 방법들은 적응적 이진화에서 사용되는 박스에 대한 크기 설정 문제를 가지고 있다. 이 문제로 기존 방법들은 이차원 바코드 영상 인식에 적용하기에 부적절하다. 문제점을 극복하기 위해 먼저 박스크기와 기존 방법들의 문제점을 분석하고, 이를 기반으로 적분영상을 사용한 새로운 적응형 이진화 방법을 소개한다. 제안한 방법의 성능 입증을 위해 기존의 방법과 속도, 성능 비교 실험을 수행하였고 실험 결과는 기존 방법보다 우수함을 입증하였다. In this paper, we propose an adaptive thresholding method to binarize two-dimensional barcode images. Adaptive thresholding methods that minimize light effects convert an original image into a binary image. The methods are applied to document image binarization. The methods, however, have problems of determining box size used in adaptive thresholding. thus, they inappropriate to use in recognition of two-dimensional barcode images. To overcome the problem, we analysis the problem and propose a new adaptive threshold method using the integral image. To show the effectiveness of our method, we compared our method with the well-known existing methods in terms of visual quality and processing time. The experimental result indicates that the proposed method is superior to the existing method.

네 방향 스캔 방법을 이용한 QR코드 파인더 인식

이연경,유훈,Lee, Yeon-Kyung,Yoo, Hoon 한국정보통신학회 2012 한국정보통신학회논문지 Vol.16 No.6

본 논문에서는 네 방향으로 스캔 방향을 늘려 QR코드 파인더를 인식하는 방법을 제안한다. QR코드 인식의 첫 과정은 파인더 인식이다. 만약 파인더를 인식하지 못한다면 QR코드를 인식 할 수 없다. 기존의 QR코드 인식방법은 정면에서 촬영하지 않으면 QR코드를 인식하지 못한다는 문제점을 가지고 있다. 이러한 문제점을 극복하기 위해서 네 방향으로의 스캔과 후보군 영상을 사용하여 정확하게 파인더의 위치를 찾는다. 또한 모폴로지 연산을 이용하여 파인더의 위치를 다시 추려낸다. 제안된 방법을 입증하기 위해 기존의 인식 방법과 비교 실험을 수행하였고 그 결과 제안한 방법이 기존 방법보다 QR코드 파인더 인식률에서 우수함을 입증하였다. This paper describes a method to detect QR-code finders by four-direction scanning. The finder recognition is the first step in the QR-code recognition. If the finder is missing, QR-code recognition fails. The existing QR-code recognition method has a problem that the recognition performance decreases for perspectively distored images. To overcome the problem, we introduce four-direction scanning and a candidate set image to accurately detect QR-code finders. Using morphological operations detect the QR-code finder in the candidate set image robustly. To show the effectiveness of our method, we compared our method with the well-known existing method. The experimental result indicates that the proposed method is superior to the existing method in terms of the finder recognition performance.