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김주형,윤여안,이충만,유경화,Kim, Joo Hyoung,Youn, Yeoan,Lee, Choongman,Yoo, Kyung-Hwa 한국진공학회 2015 진공 이야기 Vol.2 No.1
A nanopore is a very small hole that can be used as single-molecule detector. The detection principle is based on monitoring the ionic current reduced by passage of a molecule through the nanopore as a voltage is applied across the nanopore. Here, we introduce biological nanopores and solid-state nanopores. Then, research and current trend about nanopore-based DNA biosensor and protein analysis are reviewed.