도시형생활주택 밀집지역의 주거환경분석: 부산광역시를 사례로

양동원,윤갑식 한국환경정책학회 2017 環境政策 Vol.25 No.4

본 논문은 부산광역시를 대상으로 도시형생활주택 밀집지역의 주거환경 수준을 분석하였다. 도시형생활주택 밀집지역의 주거환경 수준은 안전성, 편리성, 건강성 등 세 가지 측면에서 분석하였다. 분석결과, 도시형생활주택 밀집지역의 주거환경은 편리성 측면에서 비밀집지역보다 우수하지만, 안전성과 건강성 측면에서는 비밀집지역보다 주거환경 수준이 낮은 것으로 나타났다. 따라서 향후에는 편리성에 중점을 둔 도시형생활주택의 공급확대 정책뿐만 아니라 안전성과 건강성을 함께 확보하여 주거환경의 질을 제고할 수있는 방안마련이 필요함을 제시하였다 This study analyzes the residential environment in areas of high-density urban housing in the city of Busan. The quality of the residential environment for areas of high-density urban housing was analyzed in the three important aspects of safety, convenience, and health. As a result, areas of high-density urban housing showed a higher level of convenience, but the level of safety and health was shown to be lower than that in low-density areas. Therefore, the results of this study suggest a need to improve the quality of the residential environment in areas of high-density urban housing by securing safety and health as well as expanding the supply of such housing focused on convenience.

배양된 기관형적 해마 절편에서 TrkA와 p75NTR의 발현이 신경세포의 생존에 미치는 영향

양동원,권오주,김영인,김범생 대한신경과학회 2006 대한신경과학회지 Vol.24 No.6

Background: Nerve growth factor (NGF) promotes the survival and differentiation of vertebrate neurons, and their actions are mediated by two classes of cell surface receptors: tyrosine kinase A receptor (TrkA) and p75 neurotrophic receptor (p75NTR). We evaluated the role of NGF receptors in neuronal survival and the physical interactions between them. Methods: Organotypic hippocampal slices were obtained from 5 to 7-day-old rat pups and were grown for 14 days in vitro. The expression of the TrkA and p75NTR was evaluated by the western blot and immunohistochemical methods. The neuroprotective effect of NGF on the blocking of antibody-induced neuronal cell death was tested by the application of NGF (0, 50 and 150 ng/ml) to the culture media in the presence of 200 ng/ml of blocking antibodies against TrkA and p75NTR. Functional interactions between the two receptors were examined using the immunoprecipitation method. Results: TrkA and p75NTR were co-expressed in the principal neurons of the hippocampal slice culture, and the expression level was increased time dependently until 14 days of culture. The blocking antibody against each receptor induced neuronal damage in time and dose-dependent manners. NFG delayed or prevented the blocking antibody from inducing neuronal damage. Results from the immunoprecipitation experiment showed physical interactions between the two NGF receptors. Conclusions: Our results indicate that the co-expressed NGF receptors, TrkA and p75NTR, might have protective roles in the survival of neuronal cells through the cooperative interactions between them.

레이저 다이오드를 이용한 이진 신호누적 방식의 거리측정기 기술

양동원,Yang, Dong-Won 한국군사과학기술학회 2007 한국군사과학기술학회지 Vol.10 No.4

In this paper, a new design technique on the LRF which is useful for low power laser and a CBDA(Cummulative Binary Detection Algorithm) is proposed. The LD(Laser Diode) and Si-APD(Silicon Avalanche Photo Diode) are used for saving a power. In order to prove the detection range, the Si-APD binary data are accumulated before the range computation and the range finding algorithm. A prototype of the proposed DLRF(Diode Laser Range Finder) system was made and tested. An experimental result shows that the DLRF system have the same detection range using a less power(almost 1/32) than an usual military LRF. The proposed DLRF can be applied to the Unmanned Vehicles, Robot and Future Combat System of a tiny size and a low power LRF.

Korean Dementia Screeing Questionnaire (KDSQ)의 개발과 타당도 및 신뢰도의 평가

양동원,김상윤,조비룡,최진영,김범생 대한신경과학회 2002 대한신경과학회지 Vol.20 No.2

뇌혈관 장애 환자에 대한 Idebenone(CV-2619)의 임상 연구

양동원,정성우,이광수,김범생 최신의학사 1993 最新醫學 Vol.36 No.2

치매환자에서 보이는 이상 행동의 치료

양동원 대한뇌졸중학회 2000 Journal of stroke Vol.2 No.2

치매는 인지기능의 저하뿐 아니라 행동 장애를 동반한다. 그러나 치매에서의 행동장애는 인지기능의 장애만큼 사람들의 관심을 끌지 못하고, 체계적인 연구가 이루어지지 못하고 있으나 최근 들어 관심이 증가되고있다. 실제로 치매 환자를 돌보는 사람들은 환자들이 기억력이나 계산능력 등의 인지능력이 떨어져 고통을 당하는 것보다, 환자들의 공격적이고, 조절이 않되는 이상 행동 때문에 더 심한 정신적 고통, 좌절과 신체적인 고통을 당한다. 실제로 미국에서는 환자 도움이들의 50% 이상이 정신적인 고통을 호소하는 것으로 알려져 있다. 치매에서 발생하는 행동장애는 환자를 돌보는 가족이나 간병인에게 고통을 주고, 환자 자신의 신체건강을 더욱 악화 시키고, 상해를 입게 되며, 신경인지 기능의 재활치료에 방해가되며, 치매 환자들이 수용시설에 들어가게 되는 주요 원인이 되고있다. Korean Journal of Stroke 2000;2(2): 146~153

피질하 혈관성 치매 환자에서 단광자방출단층촬영과 Statistical Parametric Mapping을 이용한 뇌혈류 흐름의 분석 : Adaptation of Statistical Parametric Mapping

양동원,김범생,김의녕,손형선,김상윤 대한치매학회 2002 Dementia and Neurocognitive Disorders Vol.1 No.1

Background: Subcortical vascular dementia(SVaD) is relatively homogeneous subtype of VaD, but the mechanisms of cognitive dysfunction of subcortical VaD are not completely understood yet This study investigated the changes of cerebral blood flow(CBF) in patients with SVaD and the contribution of the white matter hyperintensity(WMHI) and clinical severity to CBF changes. Methods: 99mTc-ethyl cysteinate dimer single photon emission computed tomography(SPECT) was performed to measure the regional CBF and statistical parametric mapping(SPM)99 software was applicated to automated and objective analysis of the SPECT image data Twenty three patients (male 12, female 11) of mild to moderate dementia who met both the criteria of the DSM-IV and probable or possible NINDS-AIREN for VaD and have subcortical white matter changes and lacunar infarction on brain MRI and seventeen normal control subjects (male 7, female 10) were evaluated The severity of the WMHI was measured by semi-quantitative scale method proposed by Mantyla. The seventy of dementia was measured by clinical dementia rating (CDR) scale Results: SPM analysis of SPECT image revealed significantly reduced regional CBF in the right thalamus, left caudatd nucleus, cingulate, bilateral superior temporal, and left ventral subcallosal gyri in SVaD patients when it compared to normal controls (corrected p<0 001). Among four WMHIs, only the WMHI was associated with the small CBF reduction in the left superior temporal gyrus (uncorrected p<0 01) The reduction of CBF according to the severity of dementia was noted in the anterior and posterior association areas (uncorrected p<0 01). Conclusions: our study suggests that cognitive dysfunction of SVaD may be related with CBF reduction in the above mentioned brain areas, which probable are not associated with the severity of periventncular WMHI and dementia.

한국어판 하세가와 치매척도 개정본의 신뢰도 및 타당도의 평가

양동원,김범생,심동석,정성우,이광수,한설희,김상윤,정슬기 대한신경과학회 2004 대한신경과학회지 Vol.22 No.4

Background: The revised version of the Hasegawa Dementia Scale (HDS-R) is a useful dementia screening tool with a test for frontal lobe function and is relatively less influenced by education level and linguistic ability. We developed a Korean version of HDS-R (K-HDS) by translating the HDS-R to screen dementia patients in the Korean elderly. Methods: The basic structure of the HDS-R was preserved but some questions were modified for lingual and cultural difference. It was administrated along with the Korean version of the MMSE, Korean Dementia Screening Questionnaire, Short form Samsung Dementia Questionnaire and Clinical Dementia Rating (CDR) scales, to 151 patients (55 Alzheimer's disease, 73 vascular dementia, 23 others) with mild to moderate dementia and to 225 elderly control subjects. To screen dementia, the optimal cut-off score was estimated by receiver operating characteristic (ROC) curve analysis. By comparing the Area Under the Curve, the diagnostic efficiency of K-HDS was compared with that of K-MMSE. Results: The K-HDS had good internal consistency (Crohnbach's alpha coefficient=0.66), inter-rater reliability (r=0.95), and test-retest reliability (r=0.92). K-HDS was well correlated with the K-MMSE (r=0.84) and CDR (r=-0.67), which confirms the validity of this test. The optimal cut-off score was different according to educational level. In patients with an educational level less than 10 years, the cut-off score was 20 with the sensitivity of 87.0% and the specificity of 83%. With an educational level of 10 years or more, the cut-off score was 22 with the sensitivity of 93.0% and the specificity of 89.6%. The overall diagnostic efficiency of K-HDS was superior to that of K-MMSE especially in patients with an educational level of less than 10 years. Conclusions: The K-HDS is a reliable, valid and useful tool to screen dementia in the Korean elderly. J Korean Neurol Assoc 22(4):315~321, 2004

수열합성을 이용한 ZnO 마이크로 구조의 성장 및 전사

양동원,이원우,박원일 한국마이크로전자및패키징학회 2017 마이크로전자 및 패키징학회지 Vol.24 No.4

Recently, there has been substantial interest in flexible and wearable devices whose properties and performances are close to conventional devices on hard substrates. Despite the advancement on flexible devices with organic semiconductors or carbon nanotube films, their performances are limited by the carrier scattering at the molecular to molecular or nanotube-to-nanotube junctions. Here in this study, we demonstrate on the vertical semiconductor crystal array embedded in flexible polymer matrix. Such structures can relieve the strain effectively, thereby accommodating large flexural deformation. To achieve such structure, we first established a low-temperature solution-phase synthesis of single crystalline 3D architectures consisting of epitaxially grown ZnO constituent crystals by position and growth direction controlled growth strategy. The ZnO vertical crystal array was integrated into a piece of polydimethylsiloxane (PDMS) substrate, which was then mechanically detached from the hard substrate to achieve the freestanding ZnO-polymer composite. In addition, the characteristics of transferred ZnO were confirmed by additional structural and photoluminescent measurements. The ZnO vertical crystal array embedded in PDMS was further employed as pressure sensor that exhibited an active response to the external pressure, by piezoelectric effect of ZnO crystal. 최근, 유연하며 몸에 부착 가능한 소자들에 대한 관심이 늘어나고 있다. 이런 관심을 뒷받침 하여 이와 관련된다양한 연구들이 진행되고 있는데, 기존 딱딱한 성질을 가진 소자에 사용되던 무기물 기반의 재료의 경우 유연 소자로 만들기에 여러 가지 제약이 있어 유연하게 제작할 수 있는 유기물 반도체나 탄소 나노튜브 필름 등을 이용한 소자들이 주로연구되고 개발되어 왔다. 하지만 이런 재료들을 이용한 소자의 경우 유기물 분자와 분자 사이 또는 탄소 나노튜브와 나노튜브 사이에서 전하들이 산란되는 등 재료 자체의 한계로 인해 기존의 재료를 사용한 소자들보다 전기적 성능이 떨어지는단점을 가지고 있다. 이런 단점들을 해결하기 위하여 이 연구에서는 수직 정렬된 반도체 결정 어레이를 투명 유연한 폴리머와 결합하는 방법을 이용, 고품질 나노/마이크로 반도체 결정을 유연한 기판으로 전사 시킬 수 있는 방법을 제시한다. 위와 같은 구조는 재료에 가해지는 힘을 완화 시켜줄 수 있으며, 이로 인해 큰 변형에도 재료의 손상이 없는 소자 제작이 가능하다. 이런 구조를 구현하기 위해 위치 및 크기가 정교하게 제어된 ZnO 나노막대 단결정을 저온에서 용액공정을 통하여합성시킨다. 이후 성장시킨 ZnO 단결정 어레이와 polydimethylsiloxane (PDMS) 폴리머를 결합시킨 후 단단한 기판에서기계적으로 박리시켜 ZnO/폴리머 복합체를 분리해 낸다. 추가적으로 전사된 ZnO의 결정성을 확인하기 위하여 photoluminescent 분석을 진행하였으며, ZnO/폴리머 복합체를 이용한 외부 힘에 반응하는 압력 센서를 제작하였다.

A Fast and Efficient Image Registration Algorithm using Outlier Rejection Technique based on Subimage

양동원,김도종 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.4

Image registration is a process of overlaying two or more images of the same scene taken at different times, from different viewpoints, and by different sensors. It geometrically aligns two images, the reference and sensed image. In this paper, a fast and efficient image registration algorithm is proposed for IDS (Intruder Detection System). To reduce a calculation time, outlier rejection method based on uniformity, entropy and subimage is used. An edge tapering method is applied to alleviate a boundary effect of a subimage. And it is shown that the proposed algorithm improves the accuracy and calculation time effectively.