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      • KCI등재

        LSC 진행자와의 상호작용성과 플로우가 구매 의도에 미치는 영향: 코로나 불안의 조절된 매개효과를 중심으로

        손진 ( Zhen Sun ),서교원 ( Kyowon Seo ),정보희 ( Bohee Jung ) 한국유통경영학회 2023 유통경영학회지 Vol.26 No.6

        Purpose: This study explores factors influencing the Live Streaming Commerce (LSC) market, focusing on the expanding landscape of social network service platforms. We investigate how host characteristics on TikTok, a Chinese social network service, affect viewer interactivity, flow, and purchase intentions. Additionally, we examine the impact of the COVID-19 pandemic on the rapid growth of the SNS-based LSC market. Research design, data, and methodology: Exclusively targeting Chinese consumers with TikTok experience, an online survey was conducted using the WenJuanXing survey program in China from July 27 to September 16, 2023. After a frequency analysis to assess sample characteristics, reliability was confirmed through Cronbach’s α coefficient. Substantive hypothesis testing involved the application of Hayes’ (2013) PROCESS macro models 4 and 7 to identify the mediating effect of flow and examine the moderated mediating effect of COVID-19. Results: In the case of live streaming commerce based on social network service platforms, it was confirmed that the interactivity with hosts significantly influences consumers’ flow and purchase intentions. In addition, flow exerts a positive influence on purchase intentions. We additionally confirm how the interactivity with LSC hosts influences consumer purchase intentions by validating the mediating effect of flow. Finally, we confirm that the greater the anxiety related to COVID-19, the more the mediating effect of flow is expected to increase. Implications: Our findings recommend that companies aiming for sales increase through LSC should prioritize enhancing interactivity between hosts and consumers. This research extends existing literature by uncovering the underlying mechanisms through which LSC characteristics affect purchase intentions. Our empirical investigation also verifies the impact of COVID-19 on society from the perspective of LSC.

      • SCIESCOPUSKCI등재

        포도주스 침지 제조 흑삼의 Ginsenoside Rg<sub>3</sub> 함량 변화와 Acetylcholinesterase 억제효과

        이미라,윤범식,백신,류뢰,장동량,왕춘년,왕젠,이선영,모은경,성창근,Lee, Mi-Ra,Yun, Beom-Sik,Sun, Bai-Shen,Liu, Lei,Zhang, Dong-Liang,Wang, Chun-Yan,Wang, Zhen,Ly, Sun-Young,Mo, Eun-Kyung,Sung, Chang-Keun 고려인삼학회 2009 Journal of Ginseng Research Vol.33 No.4

        흑삼의 속성제조와 ginsenoside $Rg_3$ 함량을 극대화하고자 흑삼 제조시 포도주스에 24시간 침지한 후 $120^{\circ}C$에서 30분간 3회 반복 증숙하여 흑삼을 제조한 후 HPLC 방법을 이용하여 ginsenosides를 분석하였다. 포도주스에 침지하여 제조한 흑삼의 ginsenoside $Rg_3$ 함량은 10.91 mg/g으로 구증구포 방법으로 제조한 흑삼보다 약 2배 가량 함량이 증가되었다. 총 사포닌 함량은 14.97 mg/g으로 전통적인 구증구포 방식으로 제조한 흑삼 (12.79 mg)보다 그 함량이 높았다. 흑삼의 단회투여 (200 mg/kg, p.o.)에 의한 뇌조직 AChE 활성은 투여 24시간 후에 유의적으로 억제되는 효과를 보여주었다. 따라서 본 연구에 적용한 새로운 제조방법은 ginsenoside $Rg_3$를 강화하는 흑삼의 속성제조에 효과적인 방법으로 판단된다. 또한, AChE 활성억제를 통해 흑삼이 뇌기능 개선에 대한 잠재적인 효능을 가지고 있는 것으로 사료된다. This study was conducted to develop a new method for enhancing ginsenoside $Rg_3$, which is abundant in black ginseng. The cognition-enhancing effect of black ginseng extract was investigated via the assay of acetylcholinesterase (AChE) activity. Black ginseng I was prepared through the traditional method (by steaming and drying nine times repetitions). Black ginseng II, on the other hand, was prepared by steaming the ginseng three times at $120^{\circ}C$ for 30 min after soaking it in grape juice for 24 h. The ginsenosides of white, red, and black ginseng I, and II were investigated using the HPLC method, respectively. In black ginseng II, the ginsenoside $Rg_3$ contents, which cannot be found in white ginseng, amounted to 10.91 mg/g, approximately 18 times more than that in red ginseng. In the in-vivo study, black ginseng extract (200 mg/kg, p.o.) inhibited the AChE activity after 24 h by a single administration in the brain. Thus, the new manufacturing method for black ginseng was found to more effective in the conversion of ginsenoside $Rg_3$ compared to the traditional method. Black ginseng may also have the effect of preventing the cognitive impairment induced by cholinergic dysfunction.

      • KCI등재

        녹용 추출물이 치매 동물모델의 기억력 개선과 관련효소 활성에 미치는 효과

        이미라(Mi-Ra Lee),백신(Bai-Shen Sun),고리주안(Li-Juan Gu),왕춘년(Chun-Yan Wang),방철명(Zhe-Ming Fang),왕젠(Zhen Wang),모은경(Eun-Kyoung Mo),이선영(Sun-Young Ly),성창근(Chang-Keun Sung) 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.4

        본 연구는 녹용 추출물이 scopolamine으로 기억손상을 유발한 실험동물의 기억력 개선과 AChE, MAO-B의 활성억제, 신경전달 물질인 ACh 함량을 치매 치료제인 tacrine과 비교하여 분석하였다. 공간인지력을 평가하는 Morris water maze test에서 scopolamine(2 ㎎/㎏, i.p.)으로 기억손상을 유발한 경우 4일간의 인지훈련에도 불구하고 platform을 찾아가는 escape latency 시간이 증가되었으며, tacrine과 녹용추출물 투여군은 훈련 2일째부터 유의적으로 escape latency 시간이 감소하였다. 실험 5일째 platform을 제거한 probe test에서도 녹용 추출물 처리군은 scopolamine 처리군보다도 escape latency 시간이 유의적으로 감소하여 장기기억 개선효과가 있음을 보여주었다. 뇌의 신경전달물질인 ACh 생성은 대조군 대비 scopolamine 투여군은 84.7% 감소하였으나, 녹용 추출물 투여군(97.5%)은 치매 치료제인 tacrine(97.8%)과 비슷하게 정상적인 수치로 ACh 생성량을 증가시켰다. Tacrine 처리군은 scopolamine 투여로 상승한 뇌조직과 혈청의 AChE 활성을 유의적으로 감소시켰고, 녹용 추출물 처리군은 뇌조직의 AChE 활성을 유의적으로 감소시켰다. 뇌조직의 MAO-B 활성은 그룹 간 유의적인 차이는 없었으나, tacrine과 녹용 추출물 처리군이 scopolamine 투여군보다 MAO-B 활성을 감소시키는 경향을 보였다. 따라서 녹용 추출물은 scopolamine으로 기억손상을 유발한 치매 동물모델에서 신경전달물질을 분해하는 효소의 활성을 저해함으로써 장기기억 활성을 촉진하고 콜린성 신경계를 자극하여 기억 및 학습 증진에 효과적으로 작용하는 천연물 유래 기능성 물질로 사료된다. The aim of this study was to investigate the ameliorating effects of deer antler extract on the learning and memory impairments induced by the administration of scopolamine (2 ㎎/㎏, i.p.) in rats. Tacrine was used as a positive control agent for evaluating the cognition enhancing activity of deer antler extract in scopolamine- induced amnesia models. The results showed that the deer antler extract-treated group (200 ㎎/㎏, p.o.) and the tacrine-treated group (10 ㎎/㎏, p.o.) significantly ameliorated scopolamine-induced amnesia based on the Morris water maze test. Although there was no statistical significance of brain ACh contents among the experimental groups, the brain ACh contents of the deer antler extract-treated group was slightly higher than that of the scopolamine-treated group. The inhibitory effect of deer antler extract on the acetylcholinesterase activity in the brain was significantly lower than that of scopolamine-treated group. The tacrine- and the deer antler-treated groups reduced the MAO-B activity compared to the scopolamine-treated group, but not significantly. These results suggest that the deer antler extract could be an effective agent for the prevention of the cognitive impairment induced by cholinergic dysfunction.

      • KCI등재

        홍경천(紅景天)추출물(KH101)이 강제유영 흰쥐의 피로회복에 미치는 영향

        정혁상,김은영,심은섭,이현삼,문은정,김진화,김선여,영주,낙원,Jung, Hyuk-Sang,Kim, Eun-Young,Shim, Eun-Sheb,Lee, Hyun-Sam,Moon, Eun-Jung,Jin, Zhen-Hua,Kim, Sun-Yeou,Sohn, Young-Joo,Sohn, Nak-Won 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.4

        Objectives : Rhodiola rosea has been used in herbal medicine to treat various conditions, such as antimelancholia, antifatigue, improvement of work competence and prevention of altitude sickness. In this study, we investigated effects of Rhodiola rosea extract (KH101) on fatigue in forced swimming rats. Methods : Sprague-Dawley rats were induced with fatigue by forced swimming, then rats in each group were treated with KH101. We observed changes of glucose, LDH and cortisol in serum and LDH, glycogen, hexokinase, citrate synthase MDH, SDH and CK in muscle. Results : Obtained results were as follows: 1. Continuance times of exercise significantly increased in all groups at day 1, in the 50 mg/kg concentration group at day 2, in all groups at day 3 and in the 50 mg/kg conc. group at day 4. 2. In serum, glucose significantly decreased in all concentration groups. 3. In the soleus muscle, LDH significantly decreased in the 50 mg/kg concentration group. HK significantly decreased in the 100 mg/kg conc. group. SDH significantly increased in the 100 mg/kg conc. MDH were significantly decreased in all conc. groups. 4. In the gastrocnemius muscle, HK significantly decreased in all concentration groups, while MDH significantly increased all conc. groups. Conclusions : It is concluded that the KH101 has and anti-fatigue effect in rats. Additional studies are needed to find the mechanism of the association between each single herb.

      • SCIESCOPUSKCI등재

        포도주스 침지 제조 흑삼의 Ginsenoside Rg₃ 함량 변화와 Acetylcholinesterase 억제효과

        이미라(Mi-Ra Lee),윤범식(Beom-Sik Yun),백신(Bai-Shen Sun),류뢰(Lei Liu),장동량(Dong-Liang Zhang),왕춘년(Chun-Yan Wang),왕젠(Zhen Wang),이선영(Sun-young Ly),모은경(Eun-Kyung Mo),성창근(Chang-keun Sung) 고려인삼학회 2009 Journal of Ginseng Research Vol.33 No.4

        흑삼의 속성제조와 ginsenoside Rg₃ 함량을 극대화하고자 흑삼 제조시 포도주스에 24시간 침지한 후 120℃에서 30분간 3회 반복 증숙하여 흑삼을 제조한 후 HPLC 방법을 이용하여 ginsenosides를 분석하였다. 포도주스에 침지하여 제조한 흑삼의 ginsenoside Rg3 함량은 10.91 ㎎/g으로 구증구포 방법으로 제조한 흑삼보다 약 2배 가량 함량이 증가되었다. 총 사포닌 함량은 14.97 ㎎/g으로 전통적인 구증구포 방식으로 제조한 흑삼 (12.79 ㎎)보다 그 함량이 높았다. 흑삼의 단회투여 (200 ㎎/㎏, p.o.)에 의한 뇌조직 AChE 활성은 투여 24시간 후에 유의적으로 억제되는 효과를 보여주었다. 따라서 본 연구에 적용한 새로운 제조방법은 ginsenoside Rg₃를 강화하는 흑삼의 속성제조에 효과적인 방법으로 판단된다. 또한, AChE 활성억제를 통해 흑삼이 뇌기능 개선에 대한 잠재적인 효능을 가지고 있는 것으로 사료된다. This study was conducted to develop a new method for enhancing ginsenoside Rg₃, which is abundant in black ginseng. The cognition-enhancing effect of black ginseng extract was investigated via the assay of acetylcholinesterase (AChE) activity. Black ginseng I was prepared through the traditional method (by steaming and drying nine times repetitions). Black ginseng Ⅱ, on the other hand, was prepared by steaming the ginseng three times at 120℃ for 30 min after soaking it in grape juice for 24 h. The ginsenosides of white, red, and black ginseng Ⅰ, and Ⅱ were investigated using the HPLC method, respectively. In black ginseng Ⅱ, the ginsenoside Rg₃ contents, which cannot be found in white ginseng, amounted to 10.91 ㎎/g, approximately 18 times more than that in red ginseng. In the in-vivo study, black ginseng extract (200 ㎎/㎏, p.o.) inhibited the AChE activity after 24 h by a single administration in the brain. Thus, the new manufacturing method for black ginseng was found to more effective in the conversion of ginsenoside Rg₃ compared to the traditional method. Black ginseng may also have the effect of preventing the cognitive impairment induced by cholinergic dysfunction.

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