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반혜란 ( Hye Ran Ban ),이진아 ( Jin A Lee ),박경미 ( Kyung Mi Park ),조성희 ( Seong Hee Cho ) 대한한방부인과학회 2005 大韓韓方婦人科學會誌 Vol.18 No.3
Purpose: This study was designed to evaluate the effects of oriental medicine therapy on a patient of metrorrhagia and metrostaxis with endometrial polyp. Methods: The clinical data was analyzed on a patient of metrorrhagia and metrostaxis with endometrial polyp whose main symptoms were dysfunctional uterine bleeding. A 27-year-old female who had been treated hormone replacement therapy for dysfunctional uterine bleeding at a obstetrics and gynecology became worse, so refused any more hormone replacement therapy and visited Dongsin university oriental hospital. The patient was admitted to the obstetrics and gynecology department of Dongsin university Oriental Medical Hospital, on Febrary 23, 2004 and remained until Apri 11, 2005. we treated the patient with a herb-medication, acupunture therapy, moxa therapy and etc. Results: After treatment, improvement was seen in dysfunctional uterine bleeding, generalized weakness. Conclusion: The study suggests that oriental medicine therapy is significantly effective in the treatment of metrorrhagia and metrostaxis with endometrial polyp.
조성희,반혜란,Cho Seong-Hee,Ban Hye-Ran 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.2
Background: We had treatment for two cases of Hyperemesis Gravidarum . they had difficulty in taking herbal medcine(Gamibosengtang), because of bitter taste and increased nausea and vomiting. So We used acupuncture treatment for increasing of taking herbal medicine and reduction of nausea and vomiting. Methods: The patients estimated their dgree of chief complain on a visual analogue scale and change of oral intake and change of frequency of vomiting. Result: Herbal treatment andacupuncture treatment was efficacious for Hyperemesis Gravidarum. Conclusion: More study fo herbal medicine is needed because of bitter taste.
자궁절제술 후유증을 동반한 갱년기증후군 환자 치험 1례
이진아,반혜란,양승정,박경미,조성희,Lee Jin-A,Ban Hye-Ran,Yang Seung-Joung,Park Kyung-Mi,Cho Seong-Hee 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.1
Clinical study on one case of climacteric syndrome induced hysterectomy climacteric syndrome is symptoms of physical, mental, physiological in menopausal period. Importance of treatment of climacteric symptoms was on the rise recently. I have treated one patient who has mental depression, anxiety, impatience, impotence, palpitations, facial flushing, abdominal pain in the menopausal period in Dongshin University Oriental Hospital. I took acupunture, moxibustion, cupping, and also I made herbal medicine-gamiguibitang(加味歸脾湯). As a result, I got a good effect through above methods. So I came to write this case report.
가미보허탕(加味補虛湯)으로 치료한 산후우울증 1예에 대한 임상보고
이진아,반혜란,조성희,Lee, Jin-A,Ban, Hye-Ran,Cho, Seong-Hee 대한한의학방제학회 2005 大韓韓醫學方劑學會誌 Vol.13 No.1
As woman receive many stress during pregnancy and delivery, they happen to contract to psychopathy like a postpartum depression. Postpartum depression is a serious problem if they are not treated early enough the unhappy seriousness can be resulted. A 32-yeared-old female patient with postpartum depression was taken to Dongshin University oriental medical hospital on April, 28, 2003. We diagnosed this patient as postpartum depression, which originated from and efficiency of vital energy and blood. We treated this postpartum depression patient with herb medicine(Cami-Boheo-tang),acupuncture, moxibustion, and psychical therapy. After the oriental medical treatments, the patient was improved in all complains of the postpartum disease. After this, further study and approach will be needed about the disease of the postpartum depression.
Anti-proliferative effect of Guichulpajing-Tang extract on MCF-7 cells
조성희,박경미,반혜란,Cho, Seong-Hee,Pak, Keung-Mi,Ban, Hye-Ran The Society of Korean Medicine Obstetrics and Gyne 2006 大韓韓方婦人科學會誌 Vol.19 No.1
이 연구는 MCF-7 인간 유방암 세포주에 대한 귀출파징탕(歸朮破?湯) 추출물의 증식억제효과 세포독성효과 세포사 유발효과를 확인하기 위하여 이루어졌다. MCF-7 인간 유방암 세포주는 Dulbecco's modified Eagle's medium/F12 (DMEM/F12)에 10% fetal bovine serum(FBS;Gibco) 와 항생제를 가하여 만든 배지를 이용하여 배양하였고, MCPF-7 세포를 96- well plate에 접종한 후 다양한 농도(0~2000g/ml)의 귀출파징탕(歸朮破?湯)이 든 배지로 처리하고 다양한 시간(48, 96, 192)동안 배양하여 현미경으로 관찰하고 각각 MTS assay kit를 이용하여 세포생존율을 측정하였다. 세포독성은 Sulforhodamine B assay 방법을 이용해 측정하였고 세포사 과정에서 MCF-7세포에서의 caspase 활성화를 측정하기 위해 Western blotting을 수행하여 poly ADP ribose polymerase(PARP)의 절단을 확인하였다. 실험결과 귀출파징탕(歸朮破?湯) 추출물에 의한 세포성장 및 독성효과는 시간 및 농도에 비례하는 것으로 나타났고 세포고사과정에서 작용하는 caspase의 전 기질인 PARP 절단량이 귀출파징탕(歸朮破?湯) 처리 농도와 시간에 비례하여 증가하였다. 이것은 caspase-3가 MCF-7 세포의 성장을 억제하는데 중요한 역할을 수행함을 의미한다. 따라서 귀출파징탕(歸朮破?湯)은 다양한 기전에 의해서 유방암 세포에 대한 억제효과를 가진다는 것을 인식할 수 있다.
고호연,정승민,반혜란,임영남,박정섭,전찬용,Go, Ho-Yeon,Jung, Seng-Min,Ban, Hye-Ran,Im, Young-Nam,Park, Jeung-Sup,Jun, Chan-Yong 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.1
Objective : This study was designed to evaluate the effects of oriental medicine therapy on a hyperthyroid patient. Methods : The clinical data was analyzed on a patient with hyperthyroidism whose main symptoms were burning sensation, sweaty hands, fatigue, and palpitation etc. The patient was admitted from November 16, 2003 and remained until December 6, 2003. She was treated with herbal medicine, acupuncture and moxa therapy. Results : After treatment, improvement was seen in burning sensation, sweaty hands, fatigue and palpitation etc. Conclusion: The study suggests that oriental medicine therapy is effective on the treatment of hyperthyroidism.