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Kim, Hye-Ran,Oh, In-Jae,Shin, Myung-Geun,Park, Joon-Seok,Choi, Hyun-Jung,Ban, Hee-Jung,Kim, Kyu-Sik,Kim, Young-Chul,Shin, Jong-Hee,Ryang, Dong-Wook,Suh, Soon-Pal The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.5
<P>To date, most clinical data on pro-gastrin-releasing peptide (proGRP) have been based on serum concentrations. This study evaluated the agreement between proGRP levels in fresh serum and plasma in patients with various lung diseases. Pairs of serum and EDTA plasma were collected from 49 healthy individuals. At the same time, EDTA plasma of 118 lung cancer patients and 23 patients with benign pulmonary diseases were prospectively collected. Compared to serum, plasma proGRP concentrations were higher by an average of 103.3%. Plasma proGRP was higher in malignancy (336.4 ± 925.4 pg/mL) than in benign conditions (40.1 ± 11.5 pg/mL). Small cell lung cancer (SCLC) patients showed higher levels of proGRP (1,256.3 ± 1,605.6 pg/mL) compared to other types of lung cancer. Based on the ROC curve analyses at a specificity of 95%, the diagnostic sensitivity of plasma proGRP was estimated to be 83.8% in distinguishing SCLC from all the other conditions, and 86.5% for discriminating SCLC from the nonmalignant cases. Among the SCLC cases, limited stage disease had lower levels of plasma proGRP than extensive disease. When measuring circulating levels of proGRP, the use of plasma is preferred over serum. Plasma proGRP has a potential marker for discriminating SCLC from nonmalignant conditions or non-small cell lung cancer.</P>
반혜란 ( Hye Ran Ban ),이진아 ( Jin A Lee ),박경미 ( Kyung Mi Park ),조성희 ( Seong Hee Cho ) 대한한방부인과학회 2005 大韓韓方婦人科學會誌 Vol.18 No.3
Purpose: This study was designed to evaluate the effects of oriental medicine therapy on a patient of metrorrhagia and metrostaxis with endometrial polyp. Methods: The clinical data was analyzed on a patient of metrorrhagia and metrostaxis with endometrial polyp whose main symptoms were dysfunctional uterine bleeding. A 27-year-old female who had been treated hormone replacement therapy for dysfunctional uterine bleeding at a obstetrics and gynecology became worse, so refused any more hormone replacement therapy and visited Dongsin university oriental hospital. The patient was admitted to the obstetrics and gynecology department of Dongsin university Oriental Medical Hospital, on Febrary 23, 2004 and remained until Apri 11, 2005. we treated the patient with a herb-medication, acupunture therapy, moxa therapy and etc. Results: After treatment, improvement was seen in dysfunctional uterine bleeding, generalized weakness. Conclusion: The study suggests that oriental medicine therapy is significantly effective in the treatment of metrorrhagia and metrostaxis with endometrial polyp.
조성희,반혜란,Cho Seong-Hee,Ban Hye-Ran 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.2
Background: We had treatment for two cases of Hyperemesis Gravidarum . they had difficulty in taking herbal medcine(Gamibosengtang), because of bitter taste and increased nausea and vomiting. So We used acupuncture treatment for increasing of taking herbal medicine and reduction of nausea and vomiting. Methods: The patients estimated their dgree of chief complain on a visual analogue scale and change of oral intake and change of frequency of vomiting. Result: Herbal treatment andacupuncture treatment was efficacious for Hyperemesis Gravidarum. Conclusion: More study fo herbal medicine is needed because of bitter taste.