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마이크로어레이 자료를 이용한 유전자 선택 및 분류 방법 비교
박미주,이재원 한국자료분석학회 2015 Journal of the Korean Data Analysis Society Vol.17 No.1
For classification analysis using gene expression microarray data, gene selection is necessary to discover genomic biomarkers for diagnosis and prognosis. It is important to select smaller classifier, but it is difficult to explain by biologically when the larger class size is, the larger selected genes increase. In this study, we introduced the classification methods which are nearest shrunken centroids (NSC), random forest (RF), Bayesian model averaging (BMA), eigengene-based linear discriminant analysis (ELDA), and compared these method using the real data in various situation. The evaluation of the quality was performed using number of selected genes, incorrectly grouped points and Brier score. 마이크로어레이 자료에서의 분류 분석의 목적은 중요한 소수의 유전자를 선별하여 새로운 표본에서의 선별된 유전자 정보로부터 반응범주를 정확하게 분류하고 예측하는데 있다. 생물학적 현상을 입증하기 위해서는 분류 분석에 좋은 성능을 보이는 소수의 유전자를 선별하는 것이 중요하지만 분류 집단 수가 증가할수록 선택된 유전자 수가 증가하여 생물학적 현상을 증명하기에 어려움이 있다. 본 논문에서는 최근에 많이 사용되고 있는 마이크로어레이 자료의 분류 분석 방법인 Nearest Shrunken Centroids(NSC), Random Forest(RF), Bayesian Model Averaging(BMA), Eigengene-based Linear Discriminant Analysis(ELDA)를 소개하고, 다양한 집단 수를 가진 실제 마이크로어레이 자료를 이용하여 그 방법들의 분류 성능을 비교하였다. 분류 방법의 질적 평가는 선택 유전자 수, 오분류율, Brier score를 이용하여 수행하였다.
ZnO 박막을 TCO로 사용한 염료감응형 태양전지의 제작
박미주,공대영,황문식,마재평 호남대학교 정보통신연구소 2006 정보통신연구 Vol.16 No.-
Dye-Sensitized Solar Cell was fabricated at general lab. with common and chief matters: TiO_(2) powder as semiconductor, Eosin-Y as dye, I^(-)/I_(3)^(-) as liquidus electrolyte, and Ag as bottom-electrode. And ZnO thin film as TCO was sputtered on the glass substrate. As a result, open-circuit voltage was generated in these samples. It was found that this cell that is fabricated under common conditions is commercially available.
박미주,변진석,정재광,최재갑 대한안면통증∙구강내과학회 2019 Journal of Oral Medicine and Pain Vol.44 No.2
Synovial chondromatosis (SC) is an uncommon progressive cartilaginous metaplasia of residual mesenchymal cells in synovial tissue. This disorder usually affects large joints and is rarely observed in the temporomandibular joint (TMJ). SC in TMJ is difficult to diagnose early owing to non-specific clinical symptoms. In this article, we report a patient with SC on the right TMJ, who presented with pain in the right TMJ and progressive occlusal changes, not responsive to conventional conservative temporomandibular disorder treatment for several months. This case emphasizes the importance of an accurate specific diagnosis for TMJ problems before the delivery of any treatment.
자유학기제 도입에 따른 영양교육의 현황 및 영양교사의 인식에 관한 예비조사연구
박미주,최정화,허영란 대한지역사회영양학회 2023 대한지역사회영양학회지 Vol.28 No.1
Objectives: This study aimed to investigate the current status of nutrition education via a free learning semester program (NE). The understanding of the program, the potential difficulties, and future initiatives for NE improvement were also investigated. Methods: A total number of 161 nutrition teachers from Gwangju and Jeonnam filled in a questionnaire and participated in this survey, which was performed from July to August 2019. Results: Our results showed that 8.1% of the nutrition teachers had taught nutrition education in free learning semester programs. The most frequently implemented model was subject selection, followed by club activities. Most of the nutrition teachers comprehended the purpose of NE. The attitude of nutrition teachers to NE differed by the understanding of its purpose. Positive attitude was evident due to a better understanding of the purpose by nutrition teachers. Nutrition teachers reported the most common difficulties of NE were the lack of preparation due to the heavy workload and the lack of a standard running program. The most effective method of NE was the activity classes. The experience of practicing NE influenced the choice of contents for each operating model. Nutrition teachers that were experienced in NE conducted via free learning semester programs preferred the selected topics model, but those without experience chose the career search model. Conclusions: Although some obstacles exist, nutrition teachers had a positive attitude and perceived well the importance of NE. Therefore, the awareness for the significance of NE of nutrition teachers needs to be improved. For better NE practice, it is necessary to reduce/ manage the workload of general food service. Furthermore, the development of standard running and promotion programs, and teacher training programs should be ensured.