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      • KCI등재

        A Case of Acute Hemorrhagic Edema of Infancy

        노미령,정혜진,이주희 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.SUP

        Acute hemorrhagic edema of infancy is an unusual form of leukocytoclastic vasculitis occuring in children from the age 4 months to 2 years. The etiology remains unknown. Numerous studies, however, suggest acute hemorrhagic edema of infancy as an immune-mediated vasculitis in response to a variety of antigenic stimuli. We report a case of an acute hemorrhagic edema of infancy; 11-month-old boy with a history of fever for 3 days and a history of purpuric rash on the extremities, trunk, buttock and oral mucosa for 2 days.

      • KCI등재

        Treatment and Outcomes of Melanoma in Acral Location in Korean Patients

        노미령,김지현,정기양 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.4

        Purpose: A retrospective study was conducted to review the treatment and outcomes of mainly melanomas in acral location in a single institution in Korea, and to evaluate the prognostic significance of anatomic locations of the tumor. Materials and Methods: A retrospective review was completed on 40 patients between 2001 and 2006 to obtain pertinent demographic data, tumor data, treatment characteristics,and follow-up data. Results: Forty melanoma patients were identified and analyzed. Of these, 18 were male and 22 were female patients and the mean age at the time of diagnosis was 55.9 years. Of the tumors, 65% were located on the hands and feet with acral lentiginous melanoma being the most common histological subtype. Univariate analysis for the overall melanoma survival revealed that the thickness of the tumor and the clinical stage have prognostic significances. The most significant factor as analyzed by a multivariate analysis was shown to be the advanced clinical stage. Acral melanomas did not show statistically significant differences in the age at diagnosis, thickness of the tumor, stage, ulceration, and survival rates compared to non-acral melanomas. There was also no significant difference in the survival rate between the patients treated by amputation versus wide local excision in acral melanomas. Conclusion: In Korean melanoma patients, thickness and advanced stages are significant factors for poorer prognosis. However, the location of melanoma did not have a significant prognostic value. In treating the melanomas in acral location, local wide excisions resulted in a similar prognosis compared to amputations.

      • KCI등재

        지역 독립서점 현황 및 활성화 방안 : 광주지역을 중심으로

        노미령,정경운 한국지역문화학회 2020 지역과 문화 Vol.7 No.2

        국내에서 1990년대 중반 등장하기 시작한 독립출판물 시장의 성장과 함께, 2008년에는 이 출판물들을 전문적으로 판매하는 독립서점이 문을 열었다. 2019년 말 기준, 국내 독립서 점은 총 466개로, 지난 10년 동안 급격한 성장세를 보이고 있다. 그러나 이러한 성장세만큼, 폐점하고 있는 비율도 가파르게 상승하고 있다. 이는 광주지역 독립서점 또한 유사한 상황 이다. 뒤늦게 출발해 활발한 활동으로 주목을 받았던 광주 독립서점들의 폐점비율은 전국 평균의 2배를 상회한다. 이에 본 연구는, 광주 독립서점의 현황을 파악한 후, 이들이 안고 있는 문제를 분석해 그 해법들을 찾아보고자 했다. 현재 광주 독립서점들은 북큐레이션, 다양한 부대프로그램, 북마켓 등 다양한 노력을 기 울이고 있다. 그러나 특정 분야에 집중하는 큐레이션과 프로그램, 20,30대 특정 연령층에 대한 집중, 수도권의 출판물에 대한 의존성 등의 문제를 안고 있다. 본 연구는 이에 대한 해법으로, 지역콘텐츠 기획·개발을 통한 출판물의 다양화, 취향 기반의 살롱 성격 강화, 독 립서점 네트워크 조직화, 독립서점의 체계적 인큐베이팅 등을 제시하였다. 더불어 제도적 측면에서, 지역서점인증제, 완전한 도서정가제 시행, 공급률의 공정성 등이 필요함을 제안 하였다.

      • KCI등재

        Analysis of Risk Factors to Predict Occurrence and Prognosis of Postsurgical Hypertrophic Scar Development: A Review of 4238 Cases

        노미령,조미연,이상균,김지은,이용상,장항석 연세대학교의과대학 2023 Yonsei medical journal Vol.64 No.11

        Purpose: This study aimed to identify the risk factors associated with the occurrence and prognosis of hypertrophic scarring fol lowing thyroidectomy. Materials and Methods: A total of 4238 patients who underwent thyroidectomy were included in this study. A multivariable lo gistic regression model was developed to identify the risk factors for hypertrophic scar development and its prognosis. Results: Our analysis revealed that hypertrophic scar development was associated with younger age [odds ratio (OR)=0.949, p<0.0001], male sex (OR=0.562, p<0.0001), higher body mass index (OR=1.137, p<0.0001), prominent sternocleidomastoid mus cles (OR=2.522, p<0.0001), scarring located within 1 cm of the sternal notch (OR=4.345, p<0.0001), and a history of keloid devel opment (OR=2.789, p=0.0031). Additionally, scar location within 1 cm of the sternal notch (beta=4.326, p=0.0429) and a history of keloid development (beta=23.082, p<0.0001) were found to be associated with the prognosis of hypertrophic scarring. Conclusion: The findings of this study provide valuable insights into the risk factors associated with hypertrophic scarring following thyroidectomy. Clinicians can use this information to predict the occurrence of hypertrophic scarring and its prognosis, and take preventative measures accordingly.

      • KCI등재

        Docetaxel-Induced Onycholysis: The Role of Subungual Hemorrhage and Suppuration

        노미령,조재용,유욱 연세대학교의과대학 2007 Yonsei medical journal Vol.48 No.1

        Nail changes are common side effects of taxane chemotherapeutic agents. Docetaxel (TaxotereⓇ) is known to cause a great incidence of nail change. Various types of nail changes have previously been reported as a result of treatment with taxanes. We describe 2 cases of severe nail changes induced by docetaxel. The patients had previously been diagnosed with breast cancer and advanced gastric cancer, respectively. During the course of treatment with docetaxel, nail changes became apparent in both patients. Initially, they complained of nail bed purpura. Subungual hematomas with hemopurulent discharge were later observed in several fingers. Drainage of the hemopurulent material occurred spontaneously in our cases, leading to onycholysis. Following drainage, the pain in the nail with subungual hemoprulent material was relieved immediately and spontaneous healing of the patients' nails was noticed after few months. Subungual hemorrhage and suppuration therefore are considered causes of onycholysis and the pain in these patients. Although systemic or topical antibiotics were not used to treat these patients, antibiotics may be also worthwhile to hasten the drainage of the subungual hematomas and suppuration in patients for quick relief of pain.

      • Melanocytic Nevus: 수술 vs. 시술

        노미령 ( Mi Ryung Roh ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

        Objectives: For small to medium sized congenital melanocytic nevi (CMN), the treatment of choice is staged surgical excision. Ablative lasers or pigment-specific lasers have also been recommended for lesions difficult for surgical removal or to avoid surgery. In this study, we retrospectively analyzed the results of several treatment options for CMN to find out the optimal treatment method. Methods: Patients with small to medium sized CMN were retrospectively reviewed. Treatment options were categorized into four groups: (i) Excision only; (ii) Excision followed by scar laser; (iii) Excision followed by pigment specific laser; and (iv) Laser only. Treatment response was assessed by investigator’s global assessment (IGA) score on a seven-point scale. Results: A total of 119 cases were included. Lesions were most commonly located on the face (59/119, 49.6%), measured 210cm in size (72/119, 60.5%), and treated with excision only (50/119, 42.0%). Among treatment options, excision followed by scar laser showed the highest IGA score of 6.38. Options including surgical methods showed higher IGA scores compared to laser-only treatment (P<0.01). Staged excisions and single excisions showed no difference in IGA scores. Patient satisfaction scores increased after scar laser treatment of the staged excision scar. Conclusions: For the treatment of small to medium sized CMN, treatment strategies including surgical methods are cosmetically superior to laser-only treatment. Also, the combination of surgical excision with scar laser has the potential for better clinical outcomes and patient satisfaction.

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