다형광발진의 실험적 재현 - 강력 UVA조사기구인 Metal Halide Mercury Lamp의 사용 -

김태홍(Tae Heung Kim),윤재일(Jai Il Youn),이유신(Yoo Shin Lee) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.1

We report a case of experimental reproduction of the skin lesion of polymorphous light eruption by potent UVA irradiating instrument, metal halide mercury lamp. A 20-year-old female had complained skin lesion at sun-exposed area since childhood. The skin lesion was reproduced after repetitive exposure of high dose of UVA, and the histologic feaure of the lesion was consistent with polymorphous light eruption. Metal halide mercury lamp used in this patient has hight irradiance and exclusive of UVB and UVC. It can be convenient and precise one in phototest using high doses of UVA. (Kor J Dermatol 28(l): 62 66, 1990)

Candida albicans test를 이용한 항히스타민 제제들의 광독성 반응에 관한 연구

김태홍 (Tae Heung Kim) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.2

Backgrouhd : Antihistamine drugs are used widely in many conditions. Although some antihistamines may cause a photosensitive reaction,many physicians are not awae of it. Objective: For examination of the phototoxic potential of antihistamines, we performed the Candida albiecrns test which is simple, cheap, and good for the screening of many drugs. Methods : Thirty microliters of each solute of various antihistamines were applied to the Sabraud dextrose agar plate in which Candida albicans were applied diffusly. Four hours after the application, 60J/cm fo UVA was irradiated for two days. The irradiated. plates and nonirradiated control ones were incubated in a dark room for 48 hours, and examined for lear zones arround the drug, which means a positive results for the phototoxic potential of the drugs. Results : Mequitazine, thiethylperazine, perphenazine and cllorromazine showed positive results, whereas others did not. An additional Candida albicans test using 0.1%, 0.01%, and 0.001% of the positive drugs revealed tht chlorpromazine, thiethylperazine aderphenazine showed positive results at 0.1%, but negative at 0.01 and 0.001%. Mequitazine was niegative at 0.1, 0.01, and 0,001%, Additional studies of the Candida albicans test using 5% and 10% of the diphenhydramine and dimenhydrinate, those were known photosensitizers but they slowed negative results at this study and revealed very weak posit,ive result in 10% diphenhydramine. Conclusion : A photosensitive reaction such as photoallergy and persistent light react,ion may be triggered by the phenothiazine antihistamines. Negative result in 1%, and very weak positive results in 10% diphenhydramine may be due to different mechanism of phototoxicity, or the low phototoxic potential of diphenhydrainine. (Kor J Dermatol 1993; 31(2): 191-190)

심리적 효과의 적용이 근력발휘에 미치는 영향

김태홍(Tae-Hong Kim),이종우(Jong-Woo Lee),김태흥(Tae-Heung Kim) 한국체육과학회 1994 한국체육과학회지 Vol.3 No.2

소아 악성종양 환자에서의 대상포진

김태홍(Tae Heung Kim),박경찬(Kyung Chan Park),김정애(Jeong Aee Kim),김선훈(Seon Hoon Kim),이유신(Yoo Shin Lee),안효섭(Hyo Seop Ahn) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.4

We described the clinical manifestation of herpes zoster in thirteen children with underlying malignancies. Among the associated malignancies, hematologic malignancy including acute lymphotytic leukemia was the commonest and CNS tumors were also frequently associated. Pain was mild, and some showed high fever and abnormal liver function test results. Recurrent attacks were observed in 3 cases(23%). Thoracic segment and trigeminal nerve were commonly affected. In most cases, herpes zoster developed within two years after the diagnosis of the malignancy. (Kor J Dermatol 28(4): 441 444, 1990)

Hydrochlorthiazide에 의한 광 알레르기 반응

강진수,김태홍 ( Jin Soo Kang,Tae Heung Kim ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.6

We report a case of a photoallergic reaction induced by hydrochlorthiazide ingestion in 56-year-old male. the patient had an erythematous pruritic eruptions on the face, neck, and dorsum of the hands. After phototesting, there was a decrease in the minimal erythemal dose(UVA:5J/㎠). A photopatch test with 5% hydrochlorthiazide ointment was positive. A rapid improvement of the lesions occured after the cessation of hydrochlorthiazide adminitration.

기관지 천식과 동반된 속발성 피부 홍통증

강진수(Jin Soo Kang),김태홍(Tae Heung Kim),박기범(Ki Beom Park) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.4

Erythromelalgia is a rare disorder characterized by intense hun ing pain in the distal extremities associated with erythema and increased skin temperature. The patient was a 42- year-old woman with a 5 year history of burning pain, erythema, and warmth of the skin on both hands and feet. She had been suffering from bronchiali astalima since childhood. The onset of the symptoms were temporally related to the attacks of hei bronchial asthma. Physical examination revealed mottled dusky red patches on her both ha ids and feet, and purplish acrocyanosis on the finger and toe tips. We present a case of secondary erythromelalgia associated with bronchial asthma and acrocyanosis. (Kor J Dermatol 1992;30(4):519-523)

The Pseudoscorpion Family Chthoniidae (Arachnida: Pseudoscorpionida) in Korea, with Two New Specics from the Genus Tyrannochthonius

Yong Hong(홍용),Tae Heung Kim(김태홍),Won Koo Lee(이원구) 한국동물분류학회 1996 Animal Systematics, Evolution and Diversity Vol.12 No.2

나노급 극세 금속선 다발의 압출 해석에 관한 연구

김태홍,이용신 국민대학교 생산기술연구소 2002 공학기술논문집 Vol.25 No.-

A combined process, extrusion of bimetal wire and then drawing of the bundle of those wires, is introduced to manufacture the nano-class filament wires. This new process is devised to significantly reduce the amount of work compared to the current way of manufacturing the nano-class filament wires, which uses drawing processes as many as approximately one hundred twenty times. Each filament wire is composed of two metals, outer copper ring and inner aluminum wire. As a beginning to examine the possibility of the proposed process with a bimetal wire, the first extrusion of copper-clad aluminum wire is carefully simulated. Several process parameters such as die angle, extrusion ratio and thickness ratio of clad materials are chosen to examine the deformation characteristics as well as damage evolution during extrusion.

3 차 의료기관을 내원한 서부 경남지역의 표재성 피부 진균증 환자에 대한 임상적 및 균학적 인구학적 특성별 분포

오지원,김갑형,김태홍 대한보건협회 1998 대한보건연구 Vol.24 No.1

저자들은 1994년 6월부터 1995년 5월까지 1년간 본원 피부과에 내원하여 표재성 피부 진균증으로 진단 받은 환자 295명에 대한 임상적 및 균학적 관찰을 시행하였으며, 그들의 인구학적 특성별 분포에 대해서 살펴보았다. 결과는 다음과 같다.: 1. 표재성 피부 진균증의 환자는 총 3356명의 신환자중 295명으로 8.8%를 차지하였다. 남녀별 발생빈도는 1.17 : 1로 남자에서 더 많이 발생하였고, 연령별 분포는 30대가 21.7%로 가장 많았으며, 20대에서 50대가 전체의 72.6%를 차지하였다 계절별 분포는 여름이 44.4%, 가을이 22.7%, 봄이 18.0%, 겨울이 14.9%로 주로 여름철에 발생하였다. 2. 병형별 분포는 조갑진균증이 52.2%로 가장 높았으며, 다음으로 족부백선(20.3%), 체부백선(8.5%), 완선(7.1%) 순이었다. 병형별 계절별 분포는 족부백선, 완선, 조갑진균증의 경우 모두 여름철에서 최고치를 보였다. 병형별 연령 분포에서는 조갑진균증은 30대에서 족부백선은 50대에서 높은 분포를 보였다. 병형별 지역 분포는 조갑진균증의 경우 진양군에서, 족부백선의 경우 진주시에서 다른 질환에 비해 높은 비율로 발생하였으며, 직업분포는 조갑진균증의 경우 농부, 족부백선의 경우 가사를 담당하는 환자에서 높은 비율로 나타났다. 병형별 유병기간 분포는 1년이상 10년 이하의 기간에서 조갑진균증이, 1달 이하의 기간에서는 안면백선과 두부백선이 상대적으로 높은 비율을 보였다. 3. 중복 감염은 100명(33.9%)에서 관찰할 수 있었으며, 이중 조갑진균증과 족부백선의 중복 감염이 가장 많았다. 4. KOH 검사상 양성율은 88.5%였으며, 균주의 배양 양성율은 41.7%였다. 원인 균주의 발생 분포는 Trichophyton rubrum이 45.5%로 가장 많았으며, Yeast가 37.4%(Candida albicans; 7.3%), T. mentagrophytes가 13.0%, Microsporum canis가 4.1%였다. We performed clinical, mycologic and epidemiologic studies on 295 cases of dermatomycosis in Department of Dermatology of Gyeongsang National University Hospital from June 1994 to May 1995. The results are summarized as follows : 1. The incidence of dermatomycosis was 8.8% of total out-patients. The ratio of male to female was 1.17 : 1. The incidence rate was highest in the fourth decade(21.7%). The seasonal prevalence was high in summer(44.4%), and then followed by autumn(22.7%), spring(18.0%), and winter(14.9%) in decreasing frequency. 2. The incidence of dermatomycosis in order of frequency were onychomycosis(52.2%), tinea pedis(20.3%), tinea corporis(8.5%), and tinea cruris(7.1%). Relative high frequency of tinea pedis, tinea cruris, onychomycosis was seen in summer. Onychomycosis was relative frequent in the fourth decade and tinea pedis in the sixth decade. Relative high frequency of onychomycosis was seen in patients from Chin-yang gun and tinea pedis in patients from Chin-ju si. Onychomycosis was relatively frequent in farmers and tinea pedis was relatively frequent in housewives. Most patients with onychomycosis showed long duration, and tinea faciei and tinea capitis showed relatively short duration. 3. Coexisting fungal infections were found in 100 patients(33.9%), and onychomycosis with tinea pedis was most common. 4. The positive rate for KOH mount examination was 88.5%, and the positive rate of culture on the Sabouraud's dextrose agar media was 41.7%. Trichophyton rubrum was the most common causative organism of dermatomycosis(45.5%), and then followed by Yeast(37.4%, Candida albican; 7.3%), T. mentagrophytes(13.0%), and M. conis(4.1%) in decreasing frequency.