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      • SCOPUSKCI등재

        황기(黃?) (Astragalus membranaceus Bunge.) 뿌리의 성분연구(I)

        김진숙,김연태,김정숙,Kim, Jin-Sook,Kim, Yun-Tai,Kim, Chung-Sook 한국생약학회 1996 생약학회지 Vol.27 No.4

        The roots of Korean Astragalus membranaceus Bunge. (Leguminosae), Astragali Radix, were extracted following general methods. During these extractions, first of all, 1,2-benzendicarboxylic acid diisononylester(compound A), ${\beta}-sitosterol(compound\;B)$, $3-0-{\beta}-D-galactopyranosyl-{\beta}-sitosterol(compound\;C)$ and $stigmast-4-en-6{\beta}-ol-3-one(compound\;D)$ were isolated. Three of these compounds were identified the first time isolation from the genus of Astragalus.

      • KCI등재후보

        도뇨관 삽입 전 소독제 또는 물의 사용이 요로감염 발생에 미치는 효과에 대한 체계적 문헌고찰과 메타분석

        김진숙,김미정,김국화,임다해,Kim, Jin-Sook,Kim, Mi-Jung,Kim, Kuk-Hwa,Lim, Da-Hae 한국의료질향상학회 2017 한국의료질향상학회지 Vol.23 No.2

        Purpose:The purpose of this study was to evaluate the effects of periurethral cleaning with water or antiseptics in preventing catheter-associated urinary tract infections through systemic review Methods:The randomized clinical trials published between 2000 and 2016 were searched using domestic and international databases, and five randomized studies were selected for this study. The quality of study was assessed by assessment tool from the cochrane's Risk of Bias and meta-analysis was performed using the Cochrane Review Manager software Version 5.3 (RevMan) Results: The two groups of antiinfectants used in this study include povidone-iodine and chlorhexidine, water and chlorhexidine vs water and chlorhexidine. there was no significant difference in urinary tract infection rate between the two groups. Conclusion: Based on the findings, periurethral cleaning with water is safer and cost-efficient than using antiseptics. and it can make reduce a patient's discomfort.

      • KCI등재

        고위험병원체 결핵균의 신속진단을 위한 액체배양시스템 평가

        김진숙,김승철,전보영,박승규,Kim, Jin-Sook,Kim, Seung-Cheol,Jeon, Bo-Young,Park, Seung-Kyu 한국미생물학회 2009 미생물학회지 Vol.45 No.3

        본 연구에서는 객담 내 결핵균의 배양시험과 약제 감수성 시험 방법으로서 BacT/Alert 액체 배지, Ogawa 배지 및 $L\ddot{o}wenstein$-Jensen 배지 배양법을 비교하였다. 신속 액체배양시스템은 기존의 Egg-based media (Ogawa, $L\ddot{o}wenstein$-Jensen 배지)에 비해 높은 민감도와 빠른 배양으로 결핵환자의 초기 객담 검사와 약제 감수성 시험에 널리 사용되어 왔다. 객담은 N-Acetyl-L-cystine과 4% NaOH로 처리한 후 BacT/Alert 액체 배지 시스템과 Ogawa 배지에 접종하고 배양하여 비교하였다. 결핵환자 객담 검체 135개 중 도말검사결과 양성은 95개였고, Ogawa 배지 배양결과 양성으로 확인된 수는 89개(65.9%)였으며, BacT/Alert 액체 배지에서는 97개(71.9%)가 양성으로 확인되었다. 결핵균 배양 양성 검체의 평균배양일은 Ogawa 배지에서 22.4일, BacT/Alert 액체 배지는 11.3일로 단축되는 것을 확인하였다. 약제 감수성 시험에는 32개 결핵균주를 이용하였으며, isoniazid를 첨가한 BacT/Alert 액체 배지와 $L\ddot{o}wenstein$-Jensen 배지에서의 약제 감수성 시험 검사결과 일치률은 87.5%를 보였고, rifampicin에서의 일치률은 90.6%로 나타났다. In this study, we compared the BacT/Alert liquid culture system with Ogawa and $L\ddot{o}wenstein$-Jensen (L-J) media for sputum culture and drug susceptibility test (DST) of Mycobacterium tuberculosis. Rapid liquid culture systems have been widely employed both for primary cultures of M. tuberculosis from clinical specimens and for drug susceptibility test because of its greater sensitivity and faster turn-around time than the conventional egg-based culture methods (Ogawa, $L\ddot{o}wenstein$-Jensen media). Sputum specimens were decontaminated with N-acetyl-L-cysteine (NALC)-4% NaOH and inoculated into the BacT/Alert culture bottles and Ogawa media. 95 from among 135 sputa were smear-positive, 97 (71.9%) were culture-positive by the BacT/Alert culture system, while 89 (65.9%) were positive by Ogawa media. The mean time to culture-positive by the BacT/Alert process system was about 11.3 days, which was significantly shorter than that by Ogawa media (22.4 days). Of 32 M. tuberculosis cultures examined for drug sensitivity, the concordant rate between the two methods (BacT/ Alert liquid culture system, $L\ddot{o}wenstein$-Jensen media) ranged from 87.5% for isoniazid and 90.6% for rifampicin.

      • KCI등재

        A Review of Contemporary Teleaudiology: Literature Review, Technology, and Considerations for Practicing

        김진숙,Jeon Seungik,Kim Dokyun,Shin Yerim 대한청각학회 2021 Journal of Audiology & Otology Vol.25 No.1

        The scope of teleaudiology has been noted with telehealth due to Coronavirus disease (COVID-19) recently. As the notion has been around us for more than 20 years ever since 1999, it is necessary to perceive the knowledge accurately and prepare for the successful implementation of it. Therefore, the literature review including screening and diagnostic audiometry, cochlear implants and hearing aids, and aural rehabilitation, telecommunications technology regarding several fields of teleaudiology, and considerations for practicing were identified. Although overall internet-based audiological services showed benefits in terms of outcome and accessibility, uncertainties of cost-effectiveness, the optimal level of support, and a need for further studies of many aspects for teleaudiology has arisen. In the view of technology, the store-and-forward (asynchronous/hybrid) and a real-time (synchronous) methods were introduced with one applied and nine registered patents recorded from 2004 to 2020 for the invention of teleaudiology in the United States. Also, 10 checklists were suggested for planning teleaudiology practice from prior experience in hosting the teleaudiology program. Conclusively, it is hoped that this review sheds light on recognizing and improving the existing teleaudiology services and helps overcome the challenges faced in the era of pandemic and untact world to come.

      • SCOPUSKCI등재

        황기(Astragalus membranaceus Bunge) 뿌리의 성분 연구 (II)

        김진숙,김정숙,Kim, Jin-Sook,Kim, Chung-Sook 한국생약학회 1997 생약학회지 Vol.28 No.2

        Two compounds were isolated from roots of Astragalus membranaceus Bunge. On the basis of chemical spectro scopic evidence, they were identified as Formononetin (compound E) and Linoleic acid (9Z,12Z-Octadecadienoic acid) (compound F). Linoleic acid (9Z,12Z-Octadecadienoic acid) was reported the first time from the genus Astragalus.

      • SCIESCOPUSKCI등재

        성견 치주질환 이환 발치와에 즉시 임플란트 매식술시 Titanium plasma sprayed 임프란트와 Hydroxyapatite coated 임프란트의 계면조직에 관한 연구

        김진숙,김종관,Kim, Jin-Sook,Kim, Chong-Kwan 대한치주과학회 1993 Journal of Periodontal & Implant Science Vol.23 No.3

        Dental implants have been widely used in the treatment of esthetic and functional problems of the mouth due to alveolar bone loss, after tooth extraction. The success of implantation strongly depends on osseointegration. For osseointegration, implant material, methodology, and design have been investigated. For materials, two popular materials at present are titanium and hydroxyapatite. For methods, immediate implantation is being used recently. The purpose of this study is to evaluate osseointegration between the unthreaded cylindrical TPS implant and the HA-coated implant by a histomorphometric analysis. For this analysis, experimental periodontits was induced on the 3, 4 premolars of adult dogs by the ligation of orthodontic threads. Thereafter, each tooth was extracted. TPS. Implants and HA-coated implants were immediately inserted in the extraction socket. In control group, TPS implants were immediately inserted, and In experimental group, HA implants were immediately inserted. The dogs were sacrificed after 12 weeks, then the specimens were prepared for LM and histomorphometric analysis. The conclusion of this study is as follows l. In both control and experimental group, no inflammatory cells were observed. 2. The results of the histomorphometric analysis showed that the total osseointegration was 48.5% in control group, and 68.8% in expermental group. The experimental group was higher than the control group, and the difference was not statistically significant (p<0.05). 3. The results of the histomorphometric analysis showed that the osseointegration in the hole was 40.6% in control group, and 70.2% in experimental group. The experimental group was higher than the control group, and the difference was statistically significant (p<0.05). In both control and experinental group, no inflammatory cells were observed. 4. The results of the histomorphometric analysis showed that the osseointegration in the lower part was 52.1% in control group, and 73.3% in experimental group. The experimental group was higher than the control group, and the difference was statistically significant (p<0.05). 5. In experimental group, the bone to HA interface seemed to be mixed of bone and HA. We could not distinguish HA from the bone. The HA coating was detached from the titanium surface.

      • KCI등재
      • KCI등재

        특징벡터를 사용한 얼굴 영상 인식 연구

        김진숙,강진숙,차의영,Kim Jin-Sook,Kang Jin-Sook,Cha Eui-Young 한국정보통신학회 2005 한국정보통신학회논문지 Vol.9 No.4

        Face Recognition has been an active research area because it is not difficult to acquire face image data and it is applicable in wide range area in real world. Due to the high dimensionality of a face image space, however, it is not easy to process the face images. In this paper, we propose a method to reduce the dimension of the facial data and extract the features from them. It will be solved using the method which extracts the features from holistic face images. The proposed algorithm consists of two parts. The first is the using of principal component analysis (PCA) to transform three dimensional color facial images to one dimensional gray facial images. The second is integrated linear discriminant analusis (PCA+LDA) to prevent the loss of informations in case of performing separated steps. Integrated LDA is integrated algorithm of PCA for reduction of dimension and LDA for discrimination of facial vectors. First, in case of transformation from color image to gray image, PCA(Principal Component Analysis) is performed to enhance the image contrast to raise the recognition rate. Second, integrated LDA(Linear Discriminant Analysis) combines the two steps, namely PCA for dimensionality reduction and LDA for discrimination. It makes possible to describe concise algorithm expression and to prevent the information loss in separate steps. To validate the proposed method, the algorithm is implemented and tested on well controlled face databases. 영상 인식은 영상획득이 용이하다는 것과 실생활에서 광범위하게 사용될 수 있다는 것으로 인해 활발하게 연구되고 있는 분야이다. 그러나 얼굴영상은 높은 차원의 영상공간으로 인해 이미지 처리가 쉽지 않다. 본 논문은 얼굴 영상 데이터의 차원을 특징적인 벡터로 표현하고 이러한 특징벡터를 통해 얼굴 영상을 인식하는 방법은 제안한다. 제안되는 알고리즘은 두 부분으로 나뉜다. 첫째로는 칼라 영상을 그레이 영상으로 변환할 때 RGB 세 개의 플레인의 평균이 아닌 세 플레인의 주성분을 사용하는 PCA(Principal Component Analysis)를 적용한다. PCA는 칼라 영상을 그레이 영상으로 변환하는 과정과 인식률을 높이기 위한 영상 대비 개선 과정이 동시에 수행한다. 두 번째로는 PCA와 LDA(Linear Discriminant Analysis) 방식을 하나의 과정으로 통합하는 개선된 통합 LDA 방법이다. 두 과정을 통합함으로서 간결한 알고리즘 표현이 가능하며 분리된 단계에서 있을 수 있는 정보 손실을 방지할 수 있다. 제안된 알고리즘은 잘 제어된 대용량 얼굴 데이터베이스에서 개인을 확인하는 분야에 적용되어 성능을 향상시키고 있음을 보여주었고, 추후에는 실시간 상황에서 특정 개인을 확인하는 분야의 기초 알고리즘으로 적용될 수 있다.

      • KCI등재

        방울토마토 첨가량을 달리한 당화 방울토마토죽의 항산화 및 ACE 저해 효과

        김진숙,김자영,장영은,Kim, Jin Sook,Kim, Ja Young,Chang, Young Eun 한국식품조리과학회 2012 한국식품조리과학회지 Vol.28 No.6

        This study was conducted to investigate the physiological activities of saccharified cherry tomato gruel containing different levels(0, 15, 30, and 45%) of cherry tomato puree. The total phenolic compound and flavonoids contents of saccharified cherry tomato gruel with cherry tomato puree were 1.73-5.09 mg/g and 0.28-7.01 mg/g, respectively. DPPH radical scavenging activities of saccharified cherry tomato gruel with cherry tomato puree were 8.67-92.58%, respectively. The ABTS radical scavenging activities of saccharified cherry tomato gruel with cherry tomato puree ranged from 6.02 to 61.59%. The ACE inhibitory activity of cherry tomato rice gruel increased with cherry tomato puree showed a range of 38.85-62.15%, respectively. With increasing additions of cherry tomato puree, the total phenolic compound and flavonoid contents, DPPH and ABTS radical scavenging activities and, ACE inhibitory activities were increased significantly (p<0.05). In conclusion, saccharified cherry tomato gruel could be used as a gruel processing method to in order to increase the functional values of gruels.

      • 한약재 수치에 관한 연구 (VII) -천남성의 수치방법에 의한 uracil의 함량분석-

        김진숙,Kim, Jin-Sook 한국한의학연구원 2003 한국한의학연구원논문집 Vol.9 No.2

        Arisaematis Rhizoma was processed by many methods from old literatures. The content of uracil was significantly decreased after preparation.

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