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Natural Standard Methodology를 이용한 암 보완대체의학의 근거 및 권고수준에 대한 연구
김정선,유화승,조종관,손창규,조정효,이연월,Kim, Jung-Sun,Yoo, Hwa-Seung,Cho, Chong-Kwan,Son, Chang-Gue,Cho, Jung-Hyo,Lee, Yeon-Weol 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.1
Objective : We designed this study to analyse the Natural Standard methodology and apply the results to new study and evaluation methods. Methods : We investigated the main stream of complementary and alternative medicine (CAM), the methodology of Natural Standard, guideline in CAM, and concrete 35 cancer-related herbs and dietary supplements in 98 ones. Results : There are 35 graded herbs and supplements associated with cancer in natural standard contents: 9 foods, 17 herbs, 7 amino acids, enzymes and vitamins, and 2 herbal mixture formulas. Most of them get a grade of C: unclear or conflicting scientific evidence. Conclusion : Natural Standard aims to provide high-quality, reliable information about CAM therapies to clinicians, patients, and healthcare institutions. The more demands for and use of CAM grows, the more the needs for related studies increases. According to this international and multidisciplinary collaborative effort, we have to develop how to study and evaluate the results. We need guidelines in association with the evidence and recommendations of CAM.
김정선,남규,심경희,김규원,임광식,정해영,Kim, Jung-Sun,Nam, Kyu,Shim, Kyung-Hee,Kim, Kyu-Won,Im, Kwang-Sik,Chung, Hae-Young 한국생명과학회 1996 생명과학회지 Vol.6 No.1
Oxygen free radicals are highly reactive molecules with unpaired electrons, which are produced with in aerobic cells in the course of normal metabolic events. Normally, aerobic cells are protected from the damage of free radicals by antioxidative enzymes such as superoxide dismutase (SOD), catalase, glutathione (GSH) peroxidase, GSH S-transferase and GSH reductase which scabvenge free radicals as well as nonenzymatic antioxidants such as ceruloplasmin, albumin and nontioxidants in order to elucidate antioxidative mechanisms of red ginseng. The treatment with total saponin of red ginseng significantly devreased the contents of malondialdehyde and total free radicals in the liver. On the other hand, total saponin of red ginseng significantly increased the activities of SOD, catalase and GSH reductase and nonprotein-SH level. These results suggest that total saponin of red ginseng exerts an antioxidative effect by increasing endogenous antioxidants.
Al(III) 응집제에 의한 하수처리수 중의 유기물 성상 변화
김정선,한승우,김수현,강임석,Kim, Jungsun,Han, Seungwoo,Kim, Suhyun,Kang, Limseok 대한상하수도학회 2016 상하수도학회지 Vol.30 No.3
Control degree and property changes of dissolved organic matter (DOM) were conducted by coagulation of chemical treatment for 2 sewage treatment plants with different technical methods. As the result, SUVA value of the second treated water (supernatant of the second settling pond after biological treatment) was increased and DOC was reduced in comparison with supplied raw water. And, SUVA value and DOC were reduced by coagulation after coagulation treatment of the second treated water. Properties of dissolved organic matter for 2 sewage treatment plants's DOC were divided. As the result, there was lots of hydrophilic component with hydrophilicity in case of plant A. In case of the second treated water, Plant A showed fulvic acid with little molecular weight was reduced among the hydrophobic component with hydrophobicity, but numic acide with lots of molecular weight was increased. However, in case of plant B, both fulvic acid with little molecular weight and humic acid with lots of molecular weight were increased among the hydrophobic components with hydrophilicity. Before the operation of phosphorus facility, properties of dissolved organic matter after biodegradation with effluent water showed hydrophilic components were reduced and hydrophobic components were increased. However, after coagulation treatment of the second treated water, hydrophilic components and hydrophobic components were outstandingly decreased or increased. During the biodegradation after coagulation treatment, hydrophilic components were significantly decreased and hydrophobic components were increased.
기능적 전기자극 치료기를 이용한 중풍구두가 편마비 환자의 보행에 미치는 영향
김정선,박지환,Kim, Jeong-Seon,Park, Ji-Whan 대한정형도수물리치료학회 2007 대한정형도수물리치료학회지 Vol.13 No.1
Purpose: An objective analysis and observations were to be done on hemiplegia patients that are wearing a walking support device, Stroke shoes. Their improvements in walking pace, the reduction of distance between the two knee joint, the increase of curve angle of the knee joint and their steps and the reduction of ankle joint upon swing phase were analyzed using a 20 walking analyzer. Methods: An examination was carried out to see the patients' communication skill and independent walking and then let them walk with the Stroke shoes on to get results before and after wearing it. Simi Reality Motion Systems GmbH (Germany, 2007) was used to analyze the results regarding knee joint and ankle joint angle changes of sagitta plane and coronal plane, stepping distances, distances between the knees and walking pace. Results: 1. The articulation angle of ankle joint during swing phase decreased and knee joint has shown a statistically significant increase in such value(p<0.05). 2. Only knee joint showed a significant increase in articulation angle during heel strike(p<0.05). 3. Knee joint showed a significant increase in articulation angle during toe off(p<0.05). 4. The distance between the two knees as well as their foot steps significantly decreased compared with when Stroke shoes were not worn(p<0.05). 5. Stroke shoes with FES have shown positive effects on the patients in improving their walking styles overall. (p<0.05). Conclusion: There was an improvement in rotation walking pattern by a reduction in the distance between the knees after wearing Stroke shoes with FES. Plantar flexion reduced that occurred in ankle joint during walking and flexion angle increased in knee joint, both of which improved foot drop which was a major problem in hemiplegia patients. Also it is believed that the device will have some positive influences on knee joint stiffening paralysis to aid in improving inefficient walking phases.
곤쟁이 , Archaeomysis kokuboi 에 미치는 phenol 의 급성 및 만성독성
김정선,진평 ( Jeong Seon Kim,Pyung Chin ) 한국수산과학회 1995 한국수산과학회지 Vol.28 No.1
Acute and chronic toxicity of phenol on the mortality, long-term survival and respiration rates of the mysid, Archaeomysis kokuboi adult and juvenile were examined. This experiment was conducted by static bioassay procedure with the different salinity at 25℃. In lethal test, the test animals were exposed to 6 different phenol concentrations to determine LC_(50) and LT_(50) (median lethal concentration and time) values. The LC_(50) values with the exposure time for the mysid adult ranged from 31.31ppm to 1.49ppm phenol and for the mysid juvenile ranged from 6.90ppm to 0.26ppm in all experimental groups. Mortality was increased with the decrease of salinity. The 96hr-LC_(50) values at 16, 24 and 32‰ salinity for the mysid adult were 1.49, 2.71 and 4.53ppm phenol, while the values for the mysid juvenile were 0.26, 0.56 and 0.71ppm, respectively. The ratios of 96hr-LC_(50) values for the mysid adult to those for the mysid juvenile at 16, 24 and 32‰ salinity were 5.73, 4.84 and 6.38, respectively. The mysid juveniles were more sensitive to phenol than the mysid adults. Compared LT_(50) values for the mysid adult with those for the mysid juvenile, the LT_(50) values for the mysid adult ranged from 384.7 to 29.0 hours at 1.7∼12.7ppm phenol concentrations and for the mysid juvenile ranged from 132.2 to 18.7 hours at 0.5∼6.0ppm phenol concentrations. The lowest LT_(50) values for the mysid adult and juvenile were showed at the combination of the highest experimental concentration of phenol and the lowest experimental salinity. The mysid juveniles showed lower LT_(50) values than those of adults. The chronic effects of phenol on the mysid at the sublethal effective concentration of phenol were lower in the 32‰ salinity group than 16 or 24‰ salinity groups. Oxygen consumption rates of the mysid adult were decreased with the increase of phenol concentration and exposure time, and decreased significantly in lower salinity at the same concentration of phenol.