진료를 받는 고혈압 환자의 혈압 조절과 관련된 의사 요인

김소영,조인숙,이재호,김지현,이은정,박종혁,이진석,김윤,Kim, So-Young,Cho, In-Sook,Lee, Jae-Ho,Kim, Ji-Hyun,Lee, Eun-Jung,Park, Jong-Hyock,Lee, Jin-Seok,Kim, Yoon 대한예방의학회 2007 예방의학회지 Vol.40 No.6

Objectives : Little is known about the physician-related factors that are associated with the management of Hypertension. The purpose of this study was to determine the physician-related factors associated with blood pressure control in hypertensive patients. Methods : We surveyed 154 physicians at 117 public health (subhealth) centers in Gyeonggi-do, Forty-one physicians completed the survey (response rates : 26.6%) and 31 physicians were finally included as the study subjects. Using the information obtained from the self-reported survey, we measured the physician-related factors associated with hypertension control, including their perception of hypertension, prescription patterns (combination prescription rates, specific antihypertensives prescription rates among patients with diabetes mellitus), and sociodemographic factors. We then collected data on blood pressure and medication use in patients seen by these physicians from the health center#s information system. We compared the physicians# perceived hypertension control rates with the actual rates, and then evaluated the rate of high overestimation (overestimation by more than 25% of the median degree of hypertension control rate overestimation) among the physicians. The physicians# antihypertensive prescription patterns were also evaluated. Multiple logistic regression analysis was used to evaluate the independent association between hypertension control and physician-related factors. Results : The physicians tended to overestimate the proportion of their patients with controlled blood pressure (79.5% perceived vs. 57.8% actual). The percentage of physicians with high overestimation was 35.5% (11 physicians). The physicians with lower control rates were more likely to highly overestimate their patients# control rates. Physicians with below-median actual control rates tended to prescribe fewer combination treatments for patients with uncontrolled blood pressure and angiotensin-converting enzyme inhibitors or fewer angiotensin receptor blockers for patients with diabetes mellitus. The rate of high overestimation by physicians was 1.31 times higher in patients with uncontrolled blood pressure than in patients with other conditions (OR=1.31, 95% CI : 1.17-1.48). Conclusions : Physicians have a tendency to overestimate the rates of hypertension control in their patients. Because physicians have a direct role in treatment outcomes, physicians# overestimation about hypertension management contributes to inadequate blood pressure control. Thus, interventions for improving physician# awareness regarding the management of patients with hypertension are needed.

다가불포화지방산의 공역이중결합 유도체가 흰쥐의 혈청 지질 성분에 미치는 영향

김소영,김성희,김경업,Kim, So-Young,Kim, Sung-Hee,Kim, Gyeong-Eup 한국식품영양과학회 2007 한국식품영양과학회지 Vol.36 No.9

n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid의 함량이 높은 들깨유와 함유된 다가불포화지방산을 공역이중결합 유도체화 처리한 옥수수유 및 들깨유가 흰쥐의 혈청 지질개선에 미치는 영향을 비교 검토하기 위하여 S.D.계 숫 흰쥐에게 돈지 식이를 대조군으로 하고 옥수수유 10%, 들깨유 10%, 유도체화 처리한 옥수수유 10% 및 유도체화 처리한 들깨유 10%을 급여하여 4주간 실험 사육한 후 혈청 지질성분을 분석하였다. 유도체화 처리한 옥수수유(TCO)는 가스 크로마토그래피에 의해 3개의 linoleic acid의 유도체가 확인되었고 유도체화 처리한 들깨유(TPO)에서는 5개의 linolenic acid의 유도체가 확인되었다. 체중증가량 및 식이섭취량은 유도체화 처리한 옥수수유 및 들깨유 급여군에서 유의성 있게 낮았다. 혈청 총콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮았다. HDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의적으로 높았다. 혈청 LDL 및 LDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮은 경향을 보였고, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. VLDL 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, chylomicron 농도는 유도체화 처리한 유지 급여군에서 유의성 있게 낮았고 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 혈청 유리콜레스테롤 농도는 대조군에 비해 전 실험군간에 유의적인 차이는 없는 반면 유도체화 처리한 옥수수유 및 들깨유 급여군에서 약간 낮았다. 혈청 중성지질 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 인지질 농도는 옥수수유 급여군이 대조군에 비해 약간 높게 나타난 반면 유도체화 처리한 유지 급여군은 약간 낮은 수준이었다. 이상의 결과 n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid 함량이 높은 들깨유의 공역이중결합유도체의 섭취는 혈중 총콜레스테롤, LDL-콜레스테롤, chylomicron 및 중성지질 농도를 감소시킴으로써 혈청 지질 개선효과가 있는 것으로 나타났으며, 특히 n-3계 들깨유의 공역이중결합 유도체 급여군이 혈청 지질 개선효과가 가장 큰 것으로 나타났다. This study was designed to examine the effects of n-6 PUFA rich corn oil, n-3 PUFA rich perilla oil and their conjugated double bond derivatives on serum lipids status in rats. Experimental diets containing lard (control), corn oil (CO), perilla oil (PO), conjugated double bond derivatives of n-6 PUFA rich corn oil (TCO) and n-3 PUFA rich perilla oil (TPO) at the level of 10% (w/w) were fed to male Sprague Dawley rats for 4 weeks. TCO was found to have three derivatives of linoleic acid and TPO had five derivatives of linolenic acid by GC. Serum total cholesterol levels were significantly lower in the all experimental groups than in the control group, and particularly, the lowest in TCO and TPO groups. HDL-cholesterol concentrations were a little higher in the all experimental groups than in the control group, and TCO and TPO groups were not significantly different from CO and PO groups. Serum LDL, LDL-cholesterol, chylomicron and triglyceride concentrations were significantly lower in the all experimental groups than in the control group, remarkably lower in TCO group and particularly, the lowest in the TPO group. Serum free cholesterol and cholesteryl ester concentrations were lower in TCO and TPO groups than in CO and PO groups. From the above research, TCO and TPO groups were effective on the improvement of the lipid compositions in serum and particularly, TPO group was the most effective on the improvement of serum lipids.

갈색거저리(Tenebrio molitor) 유충의 냉장 저장 중 산화 안정성에 관한 연구

김소영,손양주,김수희,김안나,이금양,황인경,Kim, So-Young,Son, Yang-Ju,Kim, Soo-Hee,Kim, An-Na,Lee, Geum-Yang,Hwang, In-Kyeong 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.1

The purpose of this study was to evaluate the changes on the characteristics of the oxidative stability of Tenebrio molitor larvae during cold storage at $4^{\circ}C$. Pretreatment for T. molitor larvae was designed into three methods: raw (R), freeze-dried (F.D.), and pan-fried (P.F.). The water content of the raw sample (61.46%) was higher than those of other samples (F.D.: 5.02%, P.F.: 3.67%) and its high water content was expected to facilitate the oxidation of the raw sample. In our results, the peroxide value and the carbonyl value of all of the samples increased and the raw sample, after storage for 18 day, showed the highest value. The pan-fried sample had no significant increase in its lactic acid content, acid value, and thiobarbituric acid value; whereas those values were increased in the raw sample and the freeze-dried sample (p<0.05). The browning reaction was more progressed in the pan-fried sample than other samples at 0 day, but there was no significant change during the storage. The raw sample and the freeze-dried sample had their browning indexes increase with the increasing storage period (p<0.05). The pan-fried sample produced less oxidation products than the freeze-dried sample, indicating that the unheated sample was more susceptible to oxidation than the heated samples. In conclusion, heating treatment and low water content would be effective for improving the safety and stability of T. molitor larvae during cold storage.

태양광 물 분해를 통한 수소 생산용 Cu₂O/CuO 이종접합 광전극의 제작 및 광전기화학적 특성

김소영,김효진,홍순구,김도진,Kim, Soyoung,Kim, Hyojin,Hong, Soon-Ku,Kim, Dojin 한국재료학회 2016 한국재료학회지 Vol.26 No.11

We report on the fabrication and characterization of a novel $Cu_2O/CuO$ heterojunction structure with CuO nanorods embedded in $Cu_2O$ thin film as an efficient photocathode for photoelectrochemical (PEC) solar water splitting. A CuO nanorod array was first prepared on an indium-tin-oxide-coated glass substrate via a seed-mediated hydrothermal synthesis method; then, a $Cu_2O$ thin film was electrodeposited onto the CuO nanorod array to form an oxide semiconductor heterostructure. The crystalline phases and morphologies of the heterojunction materials were examined using X-ray diffraction and scanning electron microscopy, as well as Raman scattering. The PEC properties of the fabricated $Cu_2O/CuO$ heterojunction photocathode were evaluated by photocurrent conversion efficiency measurements under white light illumination. From the observed PEC current density versus voltage (J-V) behavior, the $Cu_2O/CuO$ photocathode was found to exhibit negligible dark current and high photocurrent density, e.g. $-1.05mA/cm^2$ at -0.6 V vs. $Hg/HgCl_2$ in $1mM\;Na_2SO_4$ electrolyte, revealing the effective operation of the oxide heterostructure. The photocurrent conversion efficiency of the $Cu_2O/CuO$ photocathode was estimated to be 1.27% at -0.6 V vs. $Hg/HgCl_2$. Moreover, the PEC current density versus time (J-T) profile measured at -0.5 V vs. $Hg/HgCl_2$ on the $Cu_2O/CuO$ photocathode indicated a 3-fold increase in the photocurrent density compared to that of a simple $Cu_2O$ thin film photocathode. The improved PEC performance was attributed to a certain synergistic effect of the bilayer heterostructure on the light absorption and electron-hole recombination processes.

Fluent 모형을 이용한 대심도 배수터널 유입부의 통수능력 분석

김소영,김정수,윤세의,Kim,So Young,Kim,Jung Soo,Yoon,Sei Eui 한국방재학회 2014 한국방재학회논문집 Vol.14 No.2

최근 도심지역의 내수침수로 인한 침수피해를 저감시킬 수 있는 방안으로 대심도 배수터널의 설계 및 시공을 실시하고 있으나, 국내도시유역의 특성을 반영한 설계 및 시공기술에 관한 연구가 부족하다. 특히 유입유량의 흐름형상과 배제효율을 결정하는 낙차공의 중요 구조인 유입부에 대한 연구결과가 미흡한 실정이다. 그러므로 유입부의 형태 변화에 따른 흐름특성 및 통수능력의 분석 연구가 필요하다. 본 연구에서 3차원 수치모형인 Fluent 6.3 모형을 이용하여 대심도 배수터널 유입부 형태 변화에 따른 흐름특성을 비교 및 분석하였다. 또한 실험결과와 수치모의 결과를 비교 및 분석하여 유입부의 흐름특성 분석에 Fluent 6.3 모형의 적용성을 확인하였다. 유입부의 형태 변화(소용돌이형, 나선식, 접선식) 및 유입구의 경사 증가에 따른 흐름특성 분석 결과 유량배제효율은 접선식 유입부와 나선식 유입부가 거의 비슷하게 모의되었으나, 접선식 유입부가 나선식 유입부 보다 유입구의 경사 변화에 관계없이 안정적인 유입부의 통수능력을 나타내고 있다. 그러므로 국내 도시유역의 협소한 지하공간을 고려한 대심도 배수터널 유입부로는 접선식 유입부가 적합하다고 판단된다. Recently, the deep underground storm water tunnel for inundation reduction has been designed and constructed in urban areas. However, practical studies considering characteristics of domestic urban areas are insufficient. Especially, flow pattern and drainage capacity of intake structures are influenced by intake types of a drop shaft. Therefore, it is necessary to analyse flow characteristics and discharge capacity of the intake structure with change of intake types. The computational fluid dynamics (CFD) model, Fluent 6.3, was applied to investigate the flow characteristics of the drop shaft structure for various of intake types (scroll, spiral, and tangential). The Fluent model was carefully assessed by comparing simulated results with the experiment, and there was good agreement between them. The numerical simulation was carried out according to change in intake types and inlet slopes. The simulated results were showed that spiral and tangential-inlet were stably drained the rate of inflow into the drop shaft. However, the tangential-inlet was showed steady discharge capacity at intake regardless of variation of inlet slopes compared with the spiral-inlet. Therefore, the tangential-inlet was appropriate as inlet of the deep underground storm water tunnel that be able to install on narrowish underground space of urban areas.

남매에서 비슷한 시기에 발생한 Henoch-$Sch{\ddot{o}}nlein$ 자반증 2례

김소영,임인석,유병훈,Kim, So-Young,Lim, In-Seok,Yoo, Byoung-Hoon 대한소아신장학회 2000 Childhood kidney diseases Vol.4 No.2

저자들은 남매에서 3주 정도의 차이를 둔 비슷한 시기에 피부의 자반성 구진, 관절의 부종 및 관절통을 주소로 내원하여 HS 자반증으로 진단받은 두명의 환아를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) frequently follows upper respiratory infection, and one of the causes of this discase is inferred to $\beta$-hemolytic streptococcal infection, but the relationship is still unclear. familial tendency of this disease is unclear, too. Also genetic relationship of this disease has been in a controversy yet. We experienced two cases of HSP in brother and sister at similar period, and report this case with review of related literatures.

Financial Panic and Exchange Rate Overshooting during Currency Crises

김소영,Sunghyun Henry Kim 한국국제경제학회 2007 International Economic Journal Vol.21 No.1

During currency crises, some currencies depreciate more than the post-crisis exchange rate level, which can be described as exchange rate overshooting. Previous studies have claimed that a tight monetary policy, represented by an increase in the interest rate, stabilizes an exchange rate by causing currency appreciation, thereby explaining overshooting. This paper tests the hypothesis that overshooting simply reflects the overreaction of investors due to financial panic during currency crises, regardless of subsequent domestic policies. Empirical results suggest that: (1) the positive relationship between monetary tightening and the overshooting measure is very sensitive to sample selection; and (2) the measure of financial panic has a significant and positive relationship with the measure of overshooting in non-European countries.

집단적 놀이치료가 발달장애아동의 사회성 기술 향상에 미치는 효과

김소영,김민지,노효련,Kim, So-Young,Kim, Min-Ji,Ro, Hyo-Lyun 한국임상보건과학회 2014 한국임상보건과학회지 Vol.2 No.1

Purpose. The purpose of this study is to investigate effects of group play therapy program on improvement of social skills of children with developmental disabilities. Methods. With 4-year children with developmental disabilities with developmental problems, group play therapy program with 16 sections, 40minutes for each section for 16 weeks was conducted, and by using Korean infant social skills test (K-SSRSP), social skills index (SSQ) between before and after applying group play therapy program on children with developmental disabilities were compared. Results. When group play therapy are applied on children with developmental disabilities, it was found that there was improvement of social skills including problem solving, emotional expression, sense of order and self-confidence. Conclusions. According to the result of this study, if more specific studies regarding group play therapy program are conducted and they can reflect on other integrated programs, then it is expected that there will be greater synergy effects on improving not only children with developmental disabilities but also social skills of them.

디지털 X-ray 장치 제작 및 영상 처리 알고리즘 구현

김소영,박승우,이동훈,Kim, So-young,Park, Seung-woo,Lee, Dong-hoon 한국융합신호처리학회 2020 융합신호처리학회 논문지 (JISPS) Vol.21 No.4

본 연구에서 하루 종일 컴퓨터 앞에 앉아 있는 직장인들과 스마트폰을 자주 사용하는 현대인들의 생활 패턴으로 인해 발생하는 대표적인 현대 질병인 척추측만증에 대해 연구했다. 척추측만증은 우리나라 전체 인구의 80% 이상이 한 번 이상 걸리는 전형적인 합병증이다. X-ray는 이러한 합병증을 검사하는 데 사용된다. 조영제나 다른 기구 없이도 흉부, 복부, 뼈 등 다양한 부위에서 척추측만증을 쉽게 수행하고 촬영할 수 있는 비파괴검사법 X-선 발생 장치와 NI DAQ를 이용해 디지털 X-선 영상 장치를 소형화하고, X-선 차폐함 안에 영상 증배관과 Vision Assistant를 활용해 X-선 영상을 획득해 척추 상하부에 선을 그려 실시간으로 각도, 즉 곡률 등을 측정한다. 이와 같이 척추측만증 환자의 상태를 쉽게 볼 수 있도록 돕고, 현대인의 자세교정 문제를 해결하고 신속한 치료를 돕기 위해 연구를 수행되었다. This study studied scoliosis, one of the most common modern diseases caused by lifestyle patterns of office workers sitting in front of computers all day and modern people who use smart phones frequently. Scoliosis is a typical complication that takes more than 80% of the nation's total population at least once. X-ray are used to test for these complications. X-ray, a non-destructive testing method that allows scoliosis to be easily performed and filmed in various areas such as the chest, abdomen and bone without contrast agents or other instruments. We uses NI DAQ to miniaturize digital X-ray imaging devices and image intensifier in self-shielding housing with Vision Assistant for drawing lines to the top and the bottom of the spine to acquire angles, i.e. curvature in real-time. In this way, the research was conducted to see scoliosis patients and their condition easily and to help rapid treatment for solving the problem of posture correction in modern people.

빈랑자(Arecae Semen)로부터 arecoline의 분리 및 함량분석

김소영,손건호,강신정,장승엽,박정일,이경순,이승호,Kim, So-Young,Son, Kun-Ho,Kang, Shin-Jung,Chang, Seung-Yeup,Park, Jeong-Hill,Lee, Kyong-Soon,Lee, Seung-Ho 한국생약학회 2001 생약학회지 Vol.32 No.1

The seeds of Areca catechu L. has been used for the treatment of the diseases caused by parasites in East Asia. As a part of a research for standardization of crude drugs, we have determined the content of arecoline in the seeds of Arecae Semen purchased from various regions of Korea. The HPLC method for quantitative analysis of arecoline in Arecae Semen was established and reproducible results and chromatographic isolation of arecoline was accomplished successively. It suggested that the content of arecoline in Arecae Semen was $0.2726\;{\pm}\;0.05532%$.